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Global Opioid Induced Constipation Market Research Report 2025(Status and Outlook)

Publisher Bosson Research
Published Aug 03, 2025
Length 151 Pages
SKU # BOSS20299739

Description

Report Overview

Opioid-induced constipation (OIC) is a common and often debilitating side effect of opioid therapy, characterized by reduced bowel movement frequency, hard stools, and straining due to opioids' effects on the gastrointestinal tract. Unlike functional constipation, OIC is directly linked to opioid use, which binds to mu-opioid receptors in the gut, slowing motility and fluid secretion. It affects patients across chronic pain management, palliative care, and post-surgical recovery, with prevalence rates estimated between 40-80% of opioid users, depending on dosage and duration of therapy. The condition significantly impacts quality of life, often leading to reduced adherence to pain management regimens. The market for OIC treatments includes peripherally acting mu-opioid receptor antagonists (PAMORAs) like naloxegol and methylnaltrexone, laxatives, and emerging therapies targeting gut microbiota or novel mechanisms. Growth is driven by rising opioid prescriptions, increased awareness of OIC, and demand for non-laxative solutions, though reimbursement challenges and underdiagnosis remain barriers. Key players include AstraZeneca, Bausch Health, and Shionogi, with innovation focusing on efficacy and tolerability improvements. Regulatory scrutiny on opioid use and shifting prescribing patterns may influence future demand.

The global Opioid Induced Constipation market size was estimated at USD 2770.53 million in 2024 and is projected to grow at a compound annual growth rate (CAGR) of 4.65% during the forecast period.

This report provides a deep insight into the global Opioid Induced Constipation market covering all its essential aspects. This ranges from a macro overview of the market to micro details of the market size, competitive landscape, development trend, niche market, key market drivers and challenges, SWOT analysis, value chain analysis, etc.

The analysis helps the reader to shape the competition within the industries and strategies for the competitive environment to enhance the potential profit. Furthermore, it provides a simple framework for evaluating and accessing the position of the business organization. The report structure also focuses on the competitive landscape of the Global Opioid Induced Constipation Market, this report introduces in detail the market share, market performance, product situation, operation situation, etc. of the main players, which helps the readers in the industry to identify the main competitors and deeply understand the competition pattern of the market.

In a word, this report is a must-read for industry players, investors, researchers, consultants, business strategists, and all those who have any kind of stake or are planning to foray into the Opioid Induced Constipation market in any manner.

Global Opioid Induced Constipation Market: Market Segmentation Analysis

The research report includes specific segments by region (country), manufacturers, Type, and Application. Market segmentation creates subsets of a market based on product type, end-user or application, Geographic, and other factors. By understanding the market segments, the decision-maker can leverage this targeting in the product, sales, and marketing strategies. Market segments can power your product development cycles by informing how you create product offerings for different segments.

Key Company

Takeda Pharmaceuticals

Bayer

Sanofi

Mallinckrodt

Salix (Bausch Health)

AstraZeneca

Progenics Pharmaceuticals

Purdue Pharm

Nektar Therapeutics

Daiichi Sankyo

Prestige

GSK

Shionogi

Market Segmentation (by Type)

Methylnaltrexone Bromide

Lubiprostone

Naloxegol

Others

Market Segmentation (by Application)

Hospital

Pharmacy

Other

Geographic Segmentation

North America (USA, Canada, Mexico)

Europe (Germany, UK, France, Russia, Italy, Rest of Europe)

Asia-Pacific (China, Japan, South Korea, India, Southeast Asia, Rest of Asia-Pacific)

South America (Brazil, Argentina, Columbia, Rest of South America)

The Middle East and Africa (Saudi Arabia, UAE, Egypt, Nigeria, South Africa, Rest of MEA)

Key Benefits of This Market Research:

Industry drivers, restraints, and opportunities covered in the study

Neutral perspective on the market performance

Recent industry trends and developments

Competitive landscape & strategies of key players

Potential & niche segments and regions exhibiting promising growth covered

Historical, current, and projected market size, in terms of value

In-depth analysis of the Opioid Induced Constipation Market

Overview of the regional outlook of the Opioid Induced Constipation Market:

Chapter Outline

Chapter 1 mainly introduces the statistical scope of the report, market division standards, and market research methods.

Chapter 2 is an executive summary of different market segments (by region, product type, application, etc), including the market size of each market segment, future development potential, and so on. It offers a high-level view of the current state of the Opioid Induced Constipation Market and its likely evolution in the short to mid-term, and long term.

Chapter 3 makes a detailed analysis of the market's competitive landscape of the market and provides the market share, capacity, output, price, latest development plan, merger, and acquisition information of the main manufacturers in the market.

Chapter 4 is the analysis of the whole market industrial chain, including the upstream and downstream of the industry, as well as Porter's five forces analysis.

Chapter 5 introduces the latest developments of the market, the driving factors and restrictive factors of the market, the challenges and risks faced by manufacturers in the industry, and the analysis of relevant policies in the industry.

Chapter 6 provides the analysis of various market segments according to product types, covering the market size and development potential of each market segment, to help readers find the blue ocean market in different market segments.

Chapter 7 provides the analysis of various market segments according to application, covering the market size and development potential of each market segment, to help readers find the blue ocean market in different downstream markets.

Chapter 8 provides a quantitative analysis of the market size and development potential of each region and its main countries and introduces the market development, future development prospects, market space, and capacity of each country in the world.

Chapter 9 shares the main producing countries of Opioid Induced Constipation, their output value, profit level, regional supply, production capacity layout, etc. from the supply side.

Chapter 10 introduces the basic situation of the main companies in the market in detail, including product sales revenue, sales volume, price, gross profit margin, market share, product introduction, recent development, etc.

Chapter 11 provides a quantitative analysis of the market size and development potential of each region in the next five years.

Chapter 12 provides a quantitative analysis of the market size and development potential of each market segment in the next five years.

Chapter 13 is the main points and conclusions of the report.

Key Reasons to Buy this Report:

Access to date statistics compiled by our researchers. These provide you with historical and forecast data, which is analyzed to tell you why your market is set to change

This enables you to anticipate market changes to remain ahead of your competitors

You will be able to copy data from the Excel spreadsheet straight into your marketing plans, business presentations, or other strategic documents

The concise analysis, clear graph, and table format will enable you to pinpoint the information you require quickly

Provision of market value data for each segment and sub-segment

Indicates the region and segment that is expected to witness the fastest growth as well as to dominate the market

Analysis by geography highlighting the consumption of the product/service in the region as well as indicating the factors that are affecting the market within each region

Competitive landscape which incorporates the market ranking of the major players, along with new service/product launches, partnerships, business expansions, and acquisitions in the past five years of companies profiled

Extensive company profiles comprising of company overview, company insights, product benchmarking, and SWOT analysis for the major market players

The current as well as the future market outlook of the industry concerning recent developments which involve growth opportunities and drivers as well as challenges and restraints of both emerging as well as developed regions

Includes in-depth analysis of the market from various perspectives through Porter’s five forces analysis

Provides insight into the market through Value Chain

Market dynamics scenario, along with growth opportunities of the market in the years to come

Table of Contents

151 Pages
1 Research Methodology And Statistical Scope
1.1 Market Definition And Statistical Scope Of Opioid Induced Constipation
1.2 Key Market Segments
1.2.1 Opioid Induced Constipation Segment By Type
1.2.2 Opioid Induced Constipation Segment By Application
1.3 Methodology & Sources Of Information
1.3.1 Research Methodology
1.3.2 Research Process
1.3.3 Market Breakdown And Data Triangulation
1.3.4 Base Year
1.3.5 Report Assumptions & Caveats
2 Opioid Induced Constipation Market Overview
2.1 Global Market Overview
2.1.1 Global Opioid Induced Constipation Market Size (M Usd) Estimates And Forecasts (2020-2033)
2.1.2 Global Opioid Induced Constipation Sales Estimates And Forecasts (2020-2033)
2.2 Market Segment Executive Summary
2.3 Global Market Size By Region
3 Opioid Induced Constipation Market Competitive Landscape
3.1 Company Assessment Quadrant
3.2 Global Opioid Induced Constipation Product Life Cycle
3.3 Global Opioid Induced Constipation Sales By Manufacturers (2020-2025)
3.4 Global Opioid Induced Constipation Revenue Market Share By Manufacturers (2020-2025)
3.5 Opioid Induced Constipation Market Share By Company Type (Tier 1, Tier 2, And Tier 3)
3.6 Global Opioid Induced Constipation Average Price By Manufacturers (2020-2025)
3.7 Manufacturers’ Manufacturing Sites, Areas Served, And Product Types
3.8 Opioid Induced Constipation Market Competitive Situation And Trends
3.8.1 Opioid Induced Constipation Market Concentration Rate
3.8.2 Global 5 And 10 Largest Opioid Induced Constipation Players Market Share By Revenue
3.8.3 Mergers & Acquisitions, Expansion
4 Opioid Induced Constipation Industry Chain Analysis
4.1 Opioid Induced Constipation Industry Chain Analysis
4.2 Market Overview Of Key Raw Materials
4.3 Midstream Market Analysis
4.4 Downstream Customer Analysis
5 The Development And Dynamics Of Opioid Induced Constipation Market
5.1 Key Development Trends
5.2 Driving Factors
5.3 Market Challenges
5.4 Industry News
5.4.1 New Product Developments
5.4.2 Mergers & Acquisitions
5.4.3 Expansions
5.4.4 Collaboration/Supply Contracts
5.5 Pest Analysis
5.5.1 Industry Policies Analysis
5.5.2 Economic Environment Analysis
5.5.3 Social Environment Analysis
5.5.4 Technological Environment Analysis
5.6 Global Opioid Induced Constipation Market Porter's Five Forces Analysis
5.6.1 Global Trade Frictions
5.6.2 U.S. Tariff Policy – April 2025
5.6.3 Global Trade Frictions And Their Impacts To Opioid Induced Constipation Market
5.7 Esg Ratings Of Leading Companies
6 Opioid Induced Constipation Market Segmentation By Type
6.1 Evaluation Matrix Of Segment Market Development Potential (Type)
6.2 Global Opioid Induced Constipation Sales Market Share By Type (2020-2025)
6.3 Global Opioid Induced Constipation Market Size Market Share By Type (2020-2025)
6.4 Global Opioid Induced Constipation Price By Type (2020-2025)
7 Opioid Induced Constipation Market Segmentation By Application
7.1 Evaluation Matrix Of Segment Market Development Potential (Application)
7.2 Global Opioid Induced Constipation Market Sales By Application (2020-2025)
7.3 Global Opioid Induced Constipation Market Size (M Usd) By Application (2020-2025)
7.4 Global Opioid Induced Constipation Sales Growth Rate By Application (2020-2025)
8 Opioid Induced Constipation Market Sales By Region
8.1 Global Opioid Induced Constipation Sales By Region
8.1.1 Global Opioid Induced Constipation Sales By Region
8.1.2 Global Opioid Induced Constipation Sales Market Share By Region
8.2 Global Opioid Induced Constipation Market Size By Region
8.2.1 Global Opioid Induced Constipation Market Size By Region
8.2.2 Global Opioid Induced Constipation Market Size Market Share By Region
8.3 North America
8.3.1 North America Opioid Induced Constipation Sales By Country
8.3.2 North America Opioid Induced Constipation Market Size By Country
8.3.3 U.S. Market Overview
8.3.4 Canada Market Overview
8.3.5 Mexico Market Overview
8.4 Europe
8.4.1 Europe Opioid Induced Constipation Sales By Country
8.4.2 Europe Opioid Induced Constipation Market Size By Country
8.4.3 Germany Market Overview
8.4.4 France Market Overview
8.4.5 U.K. Market Overview
8.4.6 Italy Market Overview
8.4.7 Spain Market Overview
8.5 Asia Pacific
8.5.1 Asia Pacific Opioid Induced Constipation Sales By Region
8.5.2 Asia Pacific Opioid Induced Constipation Market Size By Region
8.5.3 China Market Overview
8.5.4 Japan Market Overview
8.5.5 South Korea Market Overview
8.5.6 India Market Overview
8.5.7 Southeast Asia Market Overview
8.6 South America
8.6.1 South America Opioid Induced Constipation Sales By Country
8.6.2 South America Opioid Induced Constipation Market Size By Country
8.6.3 Brazil Market Overview
8.6.4 Argentina Market Overview
8.6.5 Columbia Market Overview
8.7 Middle East And Africa
8.7.1 Middle East And Africa Opioid Induced Constipation Sales By Region
8.7.2 Middle East And Africa Opioid Induced Constipation Market Size By Region
8.7.3 Saudi Arabia Market Overview
8.7.4 Uae Market Overview
8.7.5 Egypt Market Overview
8.7.6 Nigeria Market Overview
8.7.7 South Africa Market Overview
9 Opioid Induced Constipation Market Production By Region
9.1 Global Production Of Opioid Induced Constipation By Region(2020-2025)
9.2 Global Opioid Induced Constipation Revenue Market Share By Region (2020-2025)
9.3 Global Opioid Induced Constipation Production, Revenue, Price And Gross Margin (2020-2025)
9.4 North America Opioid Induced Constipation Production
9.4.1 North America Opioid Induced Constipation Production Growth Rate (2020-2025)
9.4.2 North America Opioid Induced Constipation Production, Revenue, Price And Gross Margin (2020-2025)
9.5 Europe Opioid Induced Constipation Production
9.5.1 Europe Opioid Induced Constipation Production Growth Rate (2020-2025)
9.5.2 Europe Opioid Induced Constipation Production, Revenue, Price And Gross Margin (2020-2025)
9.6 Japan Opioid Induced Constipation Production (2020-2025)
9.6.1 Japan Opioid Induced Constipation Production Growth Rate (2020-2025)
9.6.2 Japan Opioid Induced Constipation Production, Revenue, Price And Gross Margin (2020-2025)
9.7 China Opioid Induced Constipation Production (2020-2025)
9.7.1 China Opioid Induced Constipation Production Growth Rate (2020-2025)
9.7.2 China Opioid Induced Constipation Production, Revenue, Price And Gross Margin (2020-2025)
10 Key Companies Profile
10.1 Takeda Pharmaceuticals
10.1.1 Takeda Pharmaceuticals Basic Information
10.1.2 Takeda Pharmaceuticals Opioid Induced Constipation Product Overview
10.1.3 Takeda Pharmaceuticals Opioid Induced Constipation Product Market Performance
10.1.4 Takeda Pharmaceuticals Business Overview
10.1.5 Takeda Pharmaceuticals Swot Analysis
10.1.6 Takeda Pharmaceuticals Recent Developments
10.2 Bayer
10.2.1 Bayer Basic Information
10.2.2 Bayer Opioid Induced Constipation Product Overview
10.2.3 Bayer Opioid Induced Constipation Product Market Performance
10.2.4 Bayer Business Overview
10.2.5 Bayer Swot Analysis
10.2.6 Bayer Recent Developments
10.3 Sanofi
10.3.1 Sanofi Basic Information
10.3.2 Sanofi Opioid Induced Constipation Product Overview
10.3.3 Sanofi Opioid Induced Constipation Product Market Performance
10.3.4 Sanofi Business Overview
10.3.5 Sanofi Swot Analysis
10.3.6 Sanofi Recent Developments
10.4 Mallinckrodt
10.4.1 Mallinckrodt Basic Information
10.4.2 Mallinckrodt Opioid Induced Constipation Product Overview
10.4.3 Mallinckrodt Opioid Induced Constipation Product Market Performance
10.4.4 Mallinckrodt Business Overview
10.4.5 Mallinckrodt Recent Developments
10.5 Salix (Bausch Health)
10.5.1 Salix (Bausch Health) Basic Information
10.5.2 Salix (Bausch Health) Opioid Induced Constipation Product Overview
10.5.3 Salix (Bausch Health) Opioid Induced Constipation Product Market Performance
10.5.4 Salix (Bausch Health) Business Overview
10.5.5 Salix (Bausch Health) Recent Developments
10.6 Astrazeneca
10.6.1 Astrazeneca Basic Information
10.6.2 Astrazeneca Opioid Induced Constipation Product Overview
10.6.3 Astrazeneca Opioid Induced Constipation Product Market Performance
10.6.4 Astrazeneca Business Overview
10.6.5 Astrazeneca Recent Developments
10.7 Progenics Pharmaceuticals
10.7.1 Progenics Pharmaceuticals Basic Information
10.7.2 Progenics Pharmaceuticals Opioid Induced Constipation Product Overview
10.7.3 Progenics Pharmaceuticals Opioid Induced Constipation Product Market Performance
10.7.4 Progenics Pharmaceuticals Business Overview
10.7.5 Progenics Pharmaceuticals Recent Developments
10.8 Purdue Pharm
10.8.1 Purdue Pharm Basic Information
10.8.2 Purdue Pharm Opioid Induced Constipation Product Overview
10.8.3 Purdue Pharm Opioid Induced Constipation Product Market Performance
10.8.4 Purdue Pharm Business Overview
10.8.5 Purdue Pharm Recent Developments
10.9 Nektar Therapeutics
10.9.1 Nektar Therapeutics Basic Information
10.9.2 Nektar Therapeutics Opioid Induced Constipation Product Overview
10.9.3 Nektar Therapeutics Opioid Induced Constipation Product Market Performance
10.9.4 Nektar Therapeutics Business Overview
10.9.5 Nektar Therapeutics Recent Developments
10.10 Daiichi Sankyo
10.10.1 Daiichi Sankyo Basic Information
10.10.2 Daiichi Sankyo Opioid Induced Constipation Product Overview
10.10.3 Daiichi Sankyo Opioid Induced Constipation Product Market Performance
10.10.4 Daiichi Sankyo Business Overview
10.10.5 Daiichi Sankyo Recent Developments
10.11 Prestige
10.11.1 Prestige Basic Information
10.11.2 Prestige Opioid Induced Constipation Product Overview
10.11.3 Prestige Opioid Induced Constipation Product Market Performance
10.11.4 Prestige Business Overview
10.11.5 Prestige Recent Developments
10.12 Gsk
10.12.1 Gsk Basic Information
10.12.2 Gsk Opioid Induced Constipation Product Overview
10.12.3 Gsk Opioid Induced Constipation Product Market Performance
10.12.4 Gsk Business Overview
10.12.5 Gsk Recent Developments
10.13 Shionogi
10.13.1 Shionogi Basic Information
10.13.2 Shionogi Opioid Induced Constipation Product Overview
10.13.3 Shionogi Opioid Induced Constipation Product Market Performance
10.13.4 Shionogi Business Overview
10.13.5 Shionogi Recent Developments
11 Opioid Induced Constipation Market Forecast By Region
11.1 Global Opioid Induced Constipation Market Size Forecast
11.2 Global Opioid Induced Constipation Market Forecast By Region
11.2.1 North America Market Size Forecast By Country
11.2.2 Europe Opioid Induced Constipation Market Size Forecast By Country
11.2.3 Asia Pacific Opioid Induced Constipation Market Size Forecast By Region
11.2.4 South America Opioid Induced Constipation Market Size Forecast By Country
11.2.5 Middle East And Africa Forecasted Sales Of Opioid Induced Constipation By Country
12 Forecast Market By Type And By Application (2026-2033)
12.1 Global Opioid Induced Constipation Market Forecast By Type (2026-2033)
12.1.1 Global Forecasted Sales Of Opioid Induced Constipation By Type (2026-2033)
12.1.2 Global Opioid Induced Constipation Market Size Forecast By Type (2026-2033)
12.1.3 Global Forecasted Price Of Opioid Induced Constipation By Type (2026-2033)
12.2 Global Opioid Induced Constipation Market Forecast By Application (2026-2033)
12.2.1 Global Opioid Induced Constipation Sales (K Mt) Forecast By Application
12.2.2 Global Opioid Induced Constipation Market Size (M Usd) Forecast By Application (2026-2033)
13 Conclusion And Key Findings
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