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The Global Exosome Market – Market Size, Forecast, Trials and Trends, 2024

Published Sep 01, 2024
Length 351 Pages
SKU # BFM19153720

Description

The Global Exosome Market – Market Size, Forecast, Trials and Trends, 2024


EXECUTIVE SUMMARY

Exosomes are extracellular vesicles (EVs) originating from endosomes, with sizes ranging from 30 to 150 nanometers. Secreted by nearly all cell types, exosomes play a key role in cell communication by carrying cell-specific proteins, lipids, and nucleic acids that are selectively absorbed by recipient cells.

Recent advancements in exosome technology are driving growth in their application across liquid biopsy, precision medicine, and regenerative medicine. Cancer-derived exosomes, in particular, are valuable for their ability to regulate angiogenesis, metastasis, and immunity, making them crucial for cancer detection, diagnosis, and treatment selection.

Exosome cargos offer prognostic insights for various diseases, including cardiovascular, renal, neurodegenerative, and metabolic disorders, as well as cancer. The discovery of numerous biomolecules within exosomes has spurred extensive research into their use as cancer biomarkers for detection, monitoring, and treatment.

Exosomes are present in many biofluids such as serum, plasma, urine, and saliva, making them ideal for minimally invasive diagnostics. They also serve as prognostic indicators and predictors of treatment responses. Furthermore, exosomes are being investigated for therapeutic use. For instance, exosomes can be engineered to carry therapeutic siRNA or proteins for targeted treatment of diseases caused by defective or missing molecules. Mesenchymal stem cell (MSC) derived exosomes have shown potential in reducing inflammation, preventing scar tissue formation, and modulating immune responses.

The exosome field, once underappreciated, is now rapidly evolving. Recent publications highlight the significant contributions of U.S. authors and Chinese researchers, with Dr. Susanne Gabrielsson from the Karolinska Institutet and Unicyte AG leading in relevant scientific literature.

BioInformant's global strategic report details the burgeoning exosome market, including trends in patents, grants, publications, and clinical trials. It covers industry partnerships, M&A activities, and financing, with insights into the competitive landscape and market forecasts through 2030.

Exosome-based diagnostics and therapeutics are expanding, with 388 clinical trials currently underway. Although no exosome therapeutics have received marketing approval yet, the first five products are anticipated by 2029. Exosomes offer promising advantages over traditional therapies, including targeted delivery, reduced side effects, and avoidance of immune detection.

In addition to medical applications, exosomes are also being used within cosmetics to promote skin rejuvenation, wound healing, scar revision, and hair restoration. Two exosome-based diagnostics have already received Fast Track approval from the U.S. FDA.

This comprehensive report provides:

Market analysis for exosome therapeutics, diagnostics, product/services, manufacturing technologies, and cosmetic applications
The clinical trial pipeline for exosome therapeutics, including both naïve and engineered exosomes
Approved and forthcoming products leveraging exosome diagnostics
Clinical trial activity by type, region, phase, and sponsor
Analysis of key industry metrics, including scientific publications, patents, grants, and clinical trials
Key funding events, including M&A, financing events, co-development agreements, and IPOs
Strategic partnerships and competitive insights
Market size figures, broken down by market segment and geography, with forecasts through 2030
Industry trends and future directions

This report is designed to inform market competitors who are developing exosome therapeutics, diagnostics, research products, manufacturing technologies, cosmeceuticals, and of course, ready-to-use exosomes. With the competitive nature of the exosome market, this report offers a valuable resource to stay informed and seize opportunities, without spending countless hours on research.

Table of Contents

351 Pages
    • Statement of the Report
    • Target Demographic
    • Report Sources
    • Purpose of the Report
    • Executive Summary
    • Introduction
    • Structure of an Exosome
    • Differences between Cell Therapy and Gene Therapy
    • The Shift from Cell Therapy to Exosome Therapy
    • Exosomes in the Next Ten Years
    • Interior Modification
    • Surface Modifications
    • Interior Modification
    • An Exosome Showing Modified Surface and Modified Interior
    • Publication Trends of Exosome Diagnostics and Therapeutics
    • PubMed Publications on Therapeutic Exosomes by Loading Technology
    • PubMed Papers on Exosome Isolation & Purification by Technology
    • PubMed Papers on Lipid Nanoparticles and Exosomes as Drug Carriers
    • Distribution of Exosome Publications by Disease Type
    • Exosome Publications by Cancer Type
    • Exosome Patent Publications over Time
    • Exosome Patents: Therapeutic vs. Diagnostics
    • Exosome Patent Applications by Exosome Source
    • Patents/Patent Applications by Isolation/Purification Technologies
    • Patents/Patent Applications by Type of Cargo
    • Patents/Patent Applications by Cargo Loading Methods
    • Patents/Patent Applications by Therapy Area
    • Leading Assignees of Exosome Patents
    • Exosome Patent Applications by Jurisdiction
    • Exosome Patent Applicants
    • Exosome Patent Inventors
    • Exosome Patent Owners
    • Legal Status of Exosome Patents
    • Exosome Clinical Trials by Phase of Study
    • Exosome Clinical Trials by Funder Type
    • Exosome Clinical Trials by Technology
    • Current Status of Clinical Trials using Exosomes in Treating Diseases
    • Clinical Trials using Exosomes for Diagnostic Studies
    • Major Exosome R&D Companies
    • Exosome Therapeutics in Preclinical Development
    • Ultracentrifugation (UC)
    • Ultrafiltration (UF)
    • Size Exclusion Chromatography (SEC)
    • Polymer Precipitation Method
    • Immunoaffinity Capture Method
    • Aptamer-Based Method
    • Microfluidic Technique
    • Exosome Technology Platforms Developed by Commercial Companies
    • Description of Select Exosome Technology Platforms
    • Incubation Method
    • Transfection Method
    • Sonication Method
    • Electroporation Method
    • Extrusion Method
    • Freeze/Thaw Method
    • Genetic Engineering Method
    • Key Players in the Exosome Therapeutic Space
    • Advantages in Diagnostic Applications
    • Major Indications Focused for Diagnosis
    • Most Common Targeted Exosome Biomarkers
    • Diagnostic Exosome Research
    • Key Players in the Development of Exosome Diagnostics
    • Aesthetic Exosome Treatments
    • Sources of Exosomes for Aesthetic Use
    • Science behind Dermatologically Relevant Exosomes
    • Key Players & Products
    • Popular Exosome-Based Aesthetics
    • Venture Capital Funding for Exosome companies
    • Partnership Deals in Exosome Space
    • Acquisition Deals
    • Licensing Deals
    • IPO
    • Market for Exosome Therapeutics
    • The Global Market for Ready-to-Use Purified Exosomes by Type
    • Market for Exosome Diagnostics
    • Global Exosome Technologies Market by Product Type
    • Global Exosome-Based Aesthetics (Cosmeceuticals) Market
    • The Overall Market for Exosomes
    • The Market Driver of Exosome Therapies
    • 101 Bio
    • Abbexa, Ltd.
    • AcouSort AB
    • Aegle Therapeutics
    • Aethlon Medical, Inc.
    • Akrivis Health Care Pvt., Ltd.
    • AM BioTech
    • AMS Biotechnology, Ltd. (AMSBIO)
    • AnteAGE
    • Aposcience AG
    • Aruna Bio
    • BENEV Company, Inc. (ExoCoBio)
    • BioCat GmbH
    • BioFluidica
    • Biological Dynamics, Inc.
    • Biorbyt, Ltd.
    • Bioscience Institute
    • Biosynth International, Inc.
    • BreStem Therapeutics, Inc.
    • Capricor Therapeutics
    • Carmine Therapeutics
    • Cellarcus Biosciences, Inc.
    • Cell Care Therapeutics
    • Cells for Cells
    • Cell Guidance Systems, Ltd.
    • Ciloa
    • ConvEyXO
    • Craif, Inc.
    • Creative Bioarray
    • Creative Biostructure
    • Creative Biolabs
    • Creative Medical Technology Holdings, Inc.
    • Creative Proteomics
    • CUSABIO Technology LLC
    • Diadem Biotherapeutics
    • Direct Biologics
    • Elevai Labs, Inc.
    • Entelexo Biotherapeutics
    • EriVan Bio
    • EVerZom
    • Evolutionary Biologics, Inc.
    • Evomic Science LLC
    • Evox Therapeutics, Ltd.
    • EXO Biologics
    • ExoCan Healthcare Technologies Pvt., Ltd.
    • Exocel Bio
    • Exogenus Therapeutics
    • Exokeryx, Inc.
    • ExoProTher Medical
    • ExoQure
    • EXORPHIA, Inc.
    • ExosomeDx (biotechne)
    • ExosomePlus
    • Exosome Sciences
    • ExoStemTech Co., Ltd.
    • ExoVectory
    • ExSURE Pvt. Ltd.
    • Florica Therapeutics
    • HansaBioMed Life Sciences, Ltd.
    • ILIAS Biologics, Inc.
    • INEXOPLAT, Inc.
    • Innocan Pharma
    • Innovex Therapeutics, SL
    • INOVIQ, Ltd.
    • Irazu Oncology
    • Izon Science, Ltd.
    • Kimera Labs, Inc.
    • Leading Biology, Inc.
    • LifeSpan Biosciences, Inc.
    • Lonza Group, Ltd.
    • Mantra Bio
    • Mercury Bio
    • Mercy Bioanalytics
    • Micregen, Ltd.
    • Microgentas
    • miR Scientific
    • Mursla Bio
    • MyBioSource, Inc.
    • Nano 24 (OBCDCT24)
    • NanoSomiX, Inc.
    • Nanovex Biotechnologies
    • NeurExo Sciences
    • NeuroDex, Inc.
    • Norgen Biotek Corporation
    • Novaxomx GmbH
    • Novus Biologicals
    • NurExone Biologic, Inc.
    • Oasis Diagnostics Corporation
    • NX Prenatal, Inc.
    • OmniSpirant Therapeutics
    • OncoXome, Inc.
    • Paracrine Therapeutics Pte, Ltd.
    • QIAGEN
    • Reactive Medical Labs
    • ReNeuron
    • RION Aesthetics, Inc.
    • Rivela Diagnostics
    • RoosterBio, Inc.
    • ShiftBIO
    • SOL Bio Corporation
    • SomesTech
    • Stem Cell Medicine, Ltd.
    • System Biosciences
    • Theoria Science, Inc.
    • TheraXyte
    • Thermo Fisher Scientific
    • TheraXyte Bioscience
    • The Tiny Cargo Company
    • TransGen Biotech, Co., Ltd.
    • Tymora Analytical
    • Unicyte AG
    • Urvogelbio Pvt, Ltd.
    • Versatope Therapeutics
    • VesiCURE Therapeutics
    • Vesigen Therapeutics, Inc.
    • VivaZome Therapeutics
    • ZEO ScientifiX, Inc.
    • Xosomix
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