Bone Void Fillers Market by Material Type (Composite Bone Grafts, Natural Bone Grafts, Synthetic Bone Grafts), Product Type (Granules/Powder, Paste, Putty), Application, End User, Distribution Channels - Global Forecast 2025-2032
Description
The Bone Void Fillers Market was valued at USD 3.88 billion in 2024 and is projected to grow to USD 4.19 billion in 2025, with a CAGR of 8.51%, reaching USD 7.46 billion by 2032.
Unveiling the Critical Role of Bone Void Fillers in Modern Orthopedic and Dental Procedures Shaping Patient Outcomes and Clinical Strategies
The landscape of musculoskeletal repair has witnessed a profound evolution with the emergence of bone void fillers as indispensable tools in both trauma and elective procedures. These specialized biomaterials serve to fill osseous defects created by injury or surgical intervention enhancing the body’s natural healing processes. By integrating osteoconductive scaffolds with osteoinductive factors and in certain cases osteogenic cells the latest generation of bone void fillers fosters a controlled environment for new bone formation. Clinicians now routinely rely on these products to address voids arising from fracture management joint reconstruction spinal fusion and dental bone grafting enriching patient outcomes and reducing recovery times.
Beyond their core therapeutic benefits bone void fillers have also sparked innovation in surgical workflows and supply chain models. In response to increasing procedural volumes and rising demand for minimally invasive approaches manufacturers have introduced materials in a variety of formats including granules putties and moldable pastes to simplify handling and contouring. Moreover as healthcare systems worldwide emphasize cost containment and value-based reimbursement these advanced formulations must demonstrate clear clinical advantages. Consequently understanding the fundamental properties mechanisms of action and practical applications of different material types is now crucial for decision makers across hospitals clinics and ambulatory surgical centers.
Navigating Transformative Shifts in the Bone Void Filler Landscape Driven by Technological Advances and Emerging Clinical Practices Impacting Care
Recent developments in biomaterials science and surgical technology have driven transformative shifts in how bone defects are managed. Innovations such as bioactive glass composites and next-generation calcium phosphate ceramics have improved osteoconductivity while reducing resorption rates, enabling more predictable fusion and regeneration. Meanwhile advances in 3D printing allow patient-specific scaffold geometries that conform precisely to complex defect morphologies. In parallel digital surgical planning platforms and navigation systems are streamlining preoperative workflows and facilitating minimally invasive delivery of bone void fillers, thereby reducing operative time and potential complications.
Regulatory harmonization and evolving reimbursement frameworks are also reshaping the competitive landscape. As more markets adopt value-based procurement policies, suppliers must furnish robust clinical evidence demonstrating superiority over traditional bone grafts. In addition to materials innovation, strategic partnerships between biomaterial developers and medical device companies are accelerating product launches and enhancing global distribution networks. Consequently, the dynamic interplay of technological advancement, policy reform, and collaborative alliances underscores the new era of bone void filler applications.
Assessing the Comprehensive Impact of United States Tariffs Introduced in 2025 on the Supply Chain and Cost Dynamics of Bone Void Fillers
The imposition of new tariffs by the United States in early 2025 has created ripples throughout the bone void filler supply chain, notably affecting cost structures for raw materials such as calcium phosphate and bioactive glass. Manufacturers reliant on overseas suppliers have faced elevated import duties, compelling finance and procurement teams to reassess their sourcing strategies. As a result, some providers have accelerated the localization of manufacturing operations in North America to mitigate tariff exposure and stabilize pricing for end users.
Beyond reshaping supply-side economics, the tariff environment is prompting innovation in alternative sourcing and material development. Forward-looking R&D groups are exploring domestic bioactive glass synthesis while forging partnerships with quarry operators for native calcium sulfate extraction. Concurrently, distributors are revising inventory models to buffer against potential duty escalations and currency fluctuations. These adaptive measures not only enhance resilience but also position certain market participants to capitalize on the shifting trade landscape and deliver uninterrupted clinical supply.
Uncovering Segmentation Insights Revealing How Material Types Product Forms Applications End Users and Distribution Channels Shape the Bone Void Filler Market
An in-depth understanding of market segmentation illuminates how patient needs surgical preferences and distribution pathways converge to shape demand for different bone void filler offerings. Material type remains a key axis of variation with composite bone grafts integrating multiple bioactive substances to optimize mechanical strength and biological performance. Within natural bone grafts clinicians choose from allografts that leverage donor bone matrix alongside bioactive glass granules prized for their controlled ion release or xenografts derived from bovine or porcine sources to accommodate specific surgical applications. Synthetic bone grafts present another dimension featuring bioactive glass engineered in particulate form alongside calcium phosphate ceramics that mimic mineral phase properties and calcium sulfate pastes that provide rapid resorption for certain cases.
Product type further refines market dynamics as surgeons select between granular or powder formulations when void geometry varies, paste and putty grades when handling and site conformity are priorities, and strip configurations for linear defects. Application segments offer additional nuance with adoption rates influenced by procedural complexity and reimbursement; for instance dental bone grafting employs small granule sizes and specialized barrier membranes, craniofacial surgeons demand finely milled or injectable formats, joint reconstruction spans hip knee and shoulder interventions, orthopedic trauma presents irregular defect patterns, and spinal fusion procedures target cervical lumbar or thoracic regions. End users from ambulatory surgical centers to hospitals shape procurement decisions through differing budget cycles and volume expectations, while clinics such as dental and oral surgery practices or orthopedic specialty centers drive demand for products tailored to outpatient workflows. Finally distribution channels range from traditional offline hospital supply agreements to growing direct-to-clinician online models.
Illuminating Critical Regional Dynamics in the Bone Void Filler Market Across the Americas Europe Middle East Africa and Asia Pacific to Guide Expansion Strategies
Geographic diversity exerts a profound influence on market growth trajectories and competitive dynamics. In the Americas robust healthcare infrastructure, coupled with high procedural volumes in the United States, underpins adoption of premium bone void filler products. Investment in ambulatory surgery centers further accelerates adoption of advanced paste and putty formulations favored for simplified instrumentation workflows. Meanwhile Canada and Brazil prioritize clinical guidelines that drive selection of allograft and bioactive glass solutions in both spinal fusion and orthopedic trauma cases.
Within Europe Middle East and Africa reimbursement variability and regulatory harmonization efforts create pockets of accelerated uptake alongside more cautious markets. Western European nations maintain established preferences for synthetic ceramics and composite grafts supported by rigorous clinical data, whereas emerging GCC and North African markets are characterized by rapid infrastructure development, increased surgical volumes and heightened interest in cost-effective natural graft alternatives. In Asia Pacific aging demographics coupled with expanding hospital networks in China India and Southeast Asia are fueling demand for injectable calcium phosphate paste and xenograft powders. Local manufacturing partnerships and government incentives for domestic production further contribute to market momentum across the region.
Examining the Competitive Landscape of Leading Providers in the Bone Void Filler Market Highlighting Innovations Partnerships and Strategic Advances
A handful of established players command significant influence through expansive product portfolios and deep channels of distribution. These companies continuously refine material science capabilities to introduce next-generation composites and resorbable ceramics designed for improved handling and faster osteointegration. Strategic collaborations between leading medical device manufacturers and biomaterial specialists have accelerated the roll-out of injectable formulations tailored for minimally invasive spine and trauma procedures.
Simultaneously innovative start-ups and regionally focused enterprises are disrupting traditional value chains with proprietary bioactive glass variants and advanced scaffold architectures engineered via additive manufacturing. These emerging competitors often leverage partnerships with academic institutions and clinical research centers to co-develop cutting-edge platforms and secure early adopters. Alongside targeted acquisitions and licensing agreements established providers balance innovation with scale, ensuring a dynamic competitive landscape that fosters continuous product evolution and improved patient outcomes.
Delivering Actionable Recommendations for Industry Leaders to Capitalize on Emerging Opportunities and Mitigate Challenges in the Bone Void Filler Sector
To maintain competitive advantage industry leaders must prioritize material innovation by expanding R&D investments in bioactive composites and next-generation synthetic ceramics that offer tunable resorption and enhanced osteoinduction. Pursuing strategic partnerships with academic centers and startups specializing in biomolecules or 3D printing will accelerate product pipelines and diversify intellectual property portfolios. Moreover strengthening local manufacturing capabilities near key markets can mitigate geopolitical risks while optimizing supply chain resilience against tariff fluctuations.
Engagement with healthcare payers and policy makers to align clinical evidence with favorable reimbursement pathways is also essential. By demonstrating clear value through real-world outcomes and health economic studies, manufacturers can differentiate their offerings and justify premium pricing. Finally advancing digital marketing and e-commerce platforms will unlock direct channels to ambulatory surgical centers clinicians and specialty clinics, enhancing market penetration and gathering real-time practitioner feedback for iterative product refinement.
Outlining a Robust Research Methodology Supporting the Bone Void Filler Market Study Incorporating Primary Interviews Secondary Data Analysis and Validation
This report’s findings are grounded in a rigorous mixed-methodology approach integrating qualitative and quantitative research techniques. Primary insights derive from structured interviews with orthopedic and dental surgeons procurement managers and distribution executives across major regions. These discussions were supplemented by site visits to leading hospitals and ambulatory centers to observe handling preferences and clinical workflows firsthand.
Secondary research encompassed an extensive review of peer-reviewed journals regulatory filings manufacturer technical specifications and industry conference proceedings. Data triangulation and statistical validation protocols were applied to ensure consistency and accuracy. Market segmentation frameworks were developed iteratively based on material composition product form application area end-user type and distribution pathway. This layered approach guarantees that the conclusions reflect current realities and emerging trends in the bone void filler arena.
Summarizing Key Takeaways and Strategic Implications for Stakeholders Navigating the Evolving Bone Void Filler Market Ecosystem
The evolution of bone void fillers from traditional graft substitutes to sophisticated biomaterial constructs underscores a pivotal transformation in regenerative medicine. Stakeholders must navigate a complex interplay of innovation cycles supply-chain risks regulatory landscapes and regional adoption patterns to succeed. Key takeaways include the critical role of advanced synthetic composites and bioactive glass, the necessity of adaptive sourcing strategies in response to trade policies, and the growing influence of outpatient care settings on product design.
Moving forward, industry participants who harness segmentation insights to tailor offerings across material types product formats applications and distribution channels will be best positioned to capture value. Similarly, aligning regional expansion with local clinical practices and reimbursement frameworks will unlock new growth corridors. Ultimately, this report equips decision makers with the strategic foresight needed to drive innovation adoption and secure sustainable leadership in the rapidly advancing bone void filler field.
Note: PDF & Excel + Online Access - 1 Year
Unveiling the Critical Role of Bone Void Fillers in Modern Orthopedic and Dental Procedures Shaping Patient Outcomes and Clinical Strategies
The landscape of musculoskeletal repair has witnessed a profound evolution with the emergence of bone void fillers as indispensable tools in both trauma and elective procedures. These specialized biomaterials serve to fill osseous defects created by injury or surgical intervention enhancing the body’s natural healing processes. By integrating osteoconductive scaffolds with osteoinductive factors and in certain cases osteogenic cells the latest generation of bone void fillers fosters a controlled environment for new bone formation. Clinicians now routinely rely on these products to address voids arising from fracture management joint reconstruction spinal fusion and dental bone grafting enriching patient outcomes and reducing recovery times.
Beyond their core therapeutic benefits bone void fillers have also sparked innovation in surgical workflows and supply chain models. In response to increasing procedural volumes and rising demand for minimally invasive approaches manufacturers have introduced materials in a variety of formats including granules putties and moldable pastes to simplify handling and contouring. Moreover as healthcare systems worldwide emphasize cost containment and value-based reimbursement these advanced formulations must demonstrate clear clinical advantages. Consequently understanding the fundamental properties mechanisms of action and practical applications of different material types is now crucial for decision makers across hospitals clinics and ambulatory surgical centers.
Navigating Transformative Shifts in the Bone Void Filler Landscape Driven by Technological Advances and Emerging Clinical Practices Impacting Care
Recent developments in biomaterials science and surgical technology have driven transformative shifts in how bone defects are managed. Innovations such as bioactive glass composites and next-generation calcium phosphate ceramics have improved osteoconductivity while reducing resorption rates, enabling more predictable fusion and regeneration. Meanwhile advances in 3D printing allow patient-specific scaffold geometries that conform precisely to complex defect morphologies. In parallel digital surgical planning platforms and navigation systems are streamlining preoperative workflows and facilitating minimally invasive delivery of bone void fillers, thereby reducing operative time and potential complications.
Regulatory harmonization and evolving reimbursement frameworks are also reshaping the competitive landscape. As more markets adopt value-based procurement policies, suppliers must furnish robust clinical evidence demonstrating superiority over traditional bone grafts. In addition to materials innovation, strategic partnerships between biomaterial developers and medical device companies are accelerating product launches and enhancing global distribution networks. Consequently, the dynamic interplay of technological advancement, policy reform, and collaborative alliances underscores the new era of bone void filler applications.
Assessing the Comprehensive Impact of United States Tariffs Introduced in 2025 on the Supply Chain and Cost Dynamics of Bone Void Fillers
The imposition of new tariffs by the United States in early 2025 has created ripples throughout the bone void filler supply chain, notably affecting cost structures for raw materials such as calcium phosphate and bioactive glass. Manufacturers reliant on overseas suppliers have faced elevated import duties, compelling finance and procurement teams to reassess their sourcing strategies. As a result, some providers have accelerated the localization of manufacturing operations in North America to mitigate tariff exposure and stabilize pricing for end users.
Beyond reshaping supply-side economics, the tariff environment is prompting innovation in alternative sourcing and material development. Forward-looking R&D groups are exploring domestic bioactive glass synthesis while forging partnerships with quarry operators for native calcium sulfate extraction. Concurrently, distributors are revising inventory models to buffer against potential duty escalations and currency fluctuations. These adaptive measures not only enhance resilience but also position certain market participants to capitalize on the shifting trade landscape and deliver uninterrupted clinical supply.
Uncovering Segmentation Insights Revealing How Material Types Product Forms Applications End Users and Distribution Channels Shape the Bone Void Filler Market
An in-depth understanding of market segmentation illuminates how patient needs surgical preferences and distribution pathways converge to shape demand for different bone void filler offerings. Material type remains a key axis of variation with composite bone grafts integrating multiple bioactive substances to optimize mechanical strength and biological performance. Within natural bone grafts clinicians choose from allografts that leverage donor bone matrix alongside bioactive glass granules prized for their controlled ion release or xenografts derived from bovine or porcine sources to accommodate specific surgical applications. Synthetic bone grafts present another dimension featuring bioactive glass engineered in particulate form alongside calcium phosphate ceramics that mimic mineral phase properties and calcium sulfate pastes that provide rapid resorption for certain cases.
Product type further refines market dynamics as surgeons select between granular or powder formulations when void geometry varies, paste and putty grades when handling and site conformity are priorities, and strip configurations for linear defects. Application segments offer additional nuance with adoption rates influenced by procedural complexity and reimbursement; for instance dental bone grafting employs small granule sizes and specialized barrier membranes, craniofacial surgeons demand finely milled or injectable formats, joint reconstruction spans hip knee and shoulder interventions, orthopedic trauma presents irregular defect patterns, and spinal fusion procedures target cervical lumbar or thoracic regions. End users from ambulatory surgical centers to hospitals shape procurement decisions through differing budget cycles and volume expectations, while clinics such as dental and oral surgery practices or orthopedic specialty centers drive demand for products tailored to outpatient workflows. Finally distribution channels range from traditional offline hospital supply agreements to growing direct-to-clinician online models.
Illuminating Critical Regional Dynamics in the Bone Void Filler Market Across the Americas Europe Middle East Africa and Asia Pacific to Guide Expansion Strategies
Geographic diversity exerts a profound influence on market growth trajectories and competitive dynamics. In the Americas robust healthcare infrastructure, coupled with high procedural volumes in the United States, underpins adoption of premium bone void filler products. Investment in ambulatory surgery centers further accelerates adoption of advanced paste and putty formulations favored for simplified instrumentation workflows. Meanwhile Canada and Brazil prioritize clinical guidelines that drive selection of allograft and bioactive glass solutions in both spinal fusion and orthopedic trauma cases.
Within Europe Middle East and Africa reimbursement variability and regulatory harmonization efforts create pockets of accelerated uptake alongside more cautious markets. Western European nations maintain established preferences for synthetic ceramics and composite grafts supported by rigorous clinical data, whereas emerging GCC and North African markets are characterized by rapid infrastructure development, increased surgical volumes and heightened interest in cost-effective natural graft alternatives. In Asia Pacific aging demographics coupled with expanding hospital networks in China India and Southeast Asia are fueling demand for injectable calcium phosphate paste and xenograft powders. Local manufacturing partnerships and government incentives for domestic production further contribute to market momentum across the region.
Examining the Competitive Landscape of Leading Providers in the Bone Void Filler Market Highlighting Innovations Partnerships and Strategic Advances
A handful of established players command significant influence through expansive product portfolios and deep channels of distribution. These companies continuously refine material science capabilities to introduce next-generation composites and resorbable ceramics designed for improved handling and faster osteointegration. Strategic collaborations between leading medical device manufacturers and biomaterial specialists have accelerated the roll-out of injectable formulations tailored for minimally invasive spine and trauma procedures.
Simultaneously innovative start-ups and regionally focused enterprises are disrupting traditional value chains with proprietary bioactive glass variants and advanced scaffold architectures engineered via additive manufacturing. These emerging competitors often leverage partnerships with academic institutions and clinical research centers to co-develop cutting-edge platforms and secure early adopters. Alongside targeted acquisitions and licensing agreements established providers balance innovation with scale, ensuring a dynamic competitive landscape that fosters continuous product evolution and improved patient outcomes.
Delivering Actionable Recommendations for Industry Leaders to Capitalize on Emerging Opportunities and Mitigate Challenges in the Bone Void Filler Sector
To maintain competitive advantage industry leaders must prioritize material innovation by expanding R&D investments in bioactive composites and next-generation synthetic ceramics that offer tunable resorption and enhanced osteoinduction. Pursuing strategic partnerships with academic centers and startups specializing in biomolecules or 3D printing will accelerate product pipelines and diversify intellectual property portfolios. Moreover strengthening local manufacturing capabilities near key markets can mitigate geopolitical risks while optimizing supply chain resilience against tariff fluctuations.
Engagement with healthcare payers and policy makers to align clinical evidence with favorable reimbursement pathways is also essential. By demonstrating clear value through real-world outcomes and health economic studies, manufacturers can differentiate their offerings and justify premium pricing. Finally advancing digital marketing and e-commerce platforms will unlock direct channels to ambulatory surgical centers clinicians and specialty clinics, enhancing market penetration and gathering real-time practitioner feedback for iterative product refinement.
Outlining a Robust Research Methodology Supporting the Bone Void Filler Market Study Incorporating Primary Interviews Secondary Data Analysis and Validation
This report’s findings are grounded in a rigorous mixed-methodology approach integrating qualitative and quantitative research techniques. Primary insights derive from structured interviews with orthopedic and dental surgeons procurement managers and distribution executives across major regions. These discussions were supplemented by site visits to leading hospitals and ambulatory centers to observe handling preferences and clinical workflows firsthand.
Secondary research encompassed an extensive review of peer-reviewed journals regulatory filings manufacturer technical specifications and industry conference proceedings. Data triangulation and statistical validation protocols were applied to ensure consistency and accuracy. Market segmentation frameworks were developed iteratively based on material composition product form application area end-user type and distribution pathway. This layered approach guarantees that the conclusions reflect current realities and emerging trends in the bone void filler arena.
Summarizing Key Takeaways and Strategic Implications for Stakeholders Navigating the Evolving Bone Void Filler Market Ecosystem
The evolution of bone void fillers from traditional graft substitutes to sophisticated biomaterial constructs underscores a pivotal transformation in regenerative medicine. Stakeholders must navigate a complex interplay of innovation cycles supply-chain risks regulatory landscapes and regional adoption patterns to succeed. Key takeaways include the critical role of advanced synthetic composites and bioactive glass, the necessity of adaptive sourcing strategies in response to trade policies, and the growing influence of outpatient care settings on product design.
Moving forward, industry participants who harness segmentation insights to tailor offerings across material types product formats applications and distribution channels will be best positioned to capture value. Similarly, aligning regional expansion with local clinical practices and reimbursement frameworks will unlock new growth corridors. Ultimately, this report equips decision makers with the strategic foresight needed to drive innovation adoption and secure sustainable leadership in the rapidly advancing bone void filler field.
Note: PDF & Excel + Online Access - 1 Year
Table of Contents
185 Pages
- 1. Preface
- 1.1. Objectives of the Study
- 1.2. Market Segmentation & Coverage
- 1.3. Years Considered for the Study
- 1.4. Currency
- 1.5. Language
- 1.6. Stakeholders
- 2. Research Methodology
- 3. Executive Summary
- 4. Market Overview
- 5. Market Insights
- 5.1. Advances in composite polymer-ceramic carriers providing controlled resorption rates matched to defect healing timelines
- 5.2. Emergence of stem cell embedded hydrogel carriers for enhanced osteoinduction and vascularization in large bone voids
- 5.3. Regulatory approvals driving market entry of resorbable magnesium-based scaffold materials for load-bearing applications
- 5.4. Expansion of antibiotic-loaded bone void fillers to prevent postoperative orthopedic infections and biofilm formation
- 5.5. Rising demand for injectable synthetic calcium phosphate formulations in minimally invasive spinal fusion procedures
- 5.6. Increasing integration of 3D printing technologies to create patient-specific bone void filler scaffolds
- 5.7. Growing adoption of bioactive glass composites for accelerated bone regeneration in complex defects
- 5.8. Surge in clinical trials evaluating growth factor enhanced bone void fillers for critical-size defect repair in long bones
- 6. Cumulative Impact of United States Tariffs 2025
- 7. Cumulative Impact of Artificial Intelligence 2025
- 8. Bone Void Fillers Market, by Material Type
- 8.1. Composite Bone Grafts
- 8.2. Natural Bone Grafts
- 8.2.1. Allografts
- 8.2.2. Bioactive Glass
- 8.2.3. Xenografts
- 8.3. Synthetic Bone Grafts
- 8.3.1. Bioactive Glass
- 8.3.2. Calcium Phosphate
- 8.3.3. Calcium Sulfate
- 9. Bone Void Fillers Market, by Product Type
- 9.1. Granules/Powder
- 9.2. Paste
- 9.3. Putty
- 9.4. Strips
- 10. Bone Void Fillers Market, by Application
- 10.1. Craniofacial Surgery
- 10.2. Dental Bone Grafting
- 10.3. Joint Reconstruction
- 10.3.1. Hip Reconstruction
- 10.3.2. Knee Reconstruction
- 10.3.3. Shoulder Reconstruction
- 10.4. Orthopedic Trauma
- 10.5. Spinal Fusion
- 10.5.1. Cervical Fusion
- 10.5.2. Lumbar Fusion
- 10.5.3. Thoracic Fusion
- 11. Bone Void Fillers Market, by End User
- 11.1. Ambulatory Surgical Centers
- 11.2. Clinics
- 11.2.1. Dental & Oral Surgery Clinics
- 11.2.2. Orthopedic Clinics
- 11.3. Hospitals
- 12. Bone Void Fillers Market, by Distribution Channels
- 12.1. Offline
- 12.2. Online
- 13. Bone Void Fillers Market, by Region
- 13.1. Americas
- 13.1.1. North America
- 13.1.2. Latin America
- 13.2. Europe, Middle East & Africa
- 13.2.1. Europe
- 13.2.2. Middle East
- 13.2.3. Africa
- 13.3. Asia-Pacific
- 14. Bone Void Fillers Market, by Group
- 14.1. ASEAN
- 14.2. GCC
- 14.3. European Union
- 14.4. BRICS
- 14.5. G7
- 14.6. NATO
- 15. Bone Void Fillers Market, by Country
- 15.1. United States
- 15.2. Canada
- 15.3. Mexico
- 15.4. Brazil
- 15.5. United Kingdom
- 15.6. Germany
- 15.7. France
- 15.8. Russia
- 15.9. Italy
- 15.10. Spain
- 15.11. China
- 15.12. India
- 15.13. Japan
- 15.14. Australia
- 15.15. South Korea
- 16. Competitive Landscape
- 16.1. Market Share Analysis, 2024
- 16.2. FPNV Positioning Matrix, 2024
- 16.3. Competitive Analysis
- 16.3.1. Acumed LLC by Colson Medical, LLC
- 16.3.2. Arthrex Inc.
- 16.3.3. B. Braun SE
- 16.3.4. Baxter International Inc.
- 16.3.5. BoneSupport AB
- 16.3.6. CaP Biomaterials, LLC
- 16.3.7. Cytophil, Inc.
- 16.3.8. Exactech, Inc.
- 16.3.9. Heraeus Group
- 16.3.10. Hoya Corporation
- 16.3.11. Integra LifeSciences Corporation
- 16.3.12. Johnson & Johnson Services, Inc.
- 16.3.13. KLS Martin Group
- 16.3.14. Medtronic PLC
- 16.3.15. Merz Pharma GmbH & Co. KGaA
- 16.3.16. NuVasive, Inc.
- 16.3.17. Orthofix Medical Inc.
- 16.3.18. Regenity Biosciences
- 16.3.19. Smith & Nephew PLC
- 16.3.20. Stryker Corporation
- 16.3.21. SYMATESE
- 16.3.22. Tecres S.p.A.
- 16.3.23. Zimmer Biomet Holdings
- 16.3.24. ZimVie Inc.
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