Market Research Logo

US Market Report for Orthopedic Growth Factor 2017 - MedCore

US Market Report for Orthopedic Growth Factor 2017 - MedCore

Growth factors are a group of small, soluble proteins that bind onto cell surface receptors, triggering a series of signals that regulate the body’s ability to grow, renew and heal. Due to the regenerative properties of growth factors, they have been exploited for bone healing in orthopedic applications. Since September 1, 2015, there are two main growth factor products offered in the U.S. market: INFUSE® by Medtronic and AUGMENT® by Wright Medical. Stryker’s OP-1™ which had been sold to Olympus Biotech is no longer available as Olympus Biotech ceased sales May 31, 2014. Stryker’s OP-1™ is a different form of bone morphogenic proteins (BMPs) that belong to a larger family of proteins called transforming growth factors.

General Report Contents

  • Market Analyses include: Unit Sales, ASPs, Market Value & Growth Trends
  • Market Drivers & Limiters for each chapter segment
  • Competitive Analysis for each chapter segment
  • Section on recent mergers & acquisitions
The U.S. market reacted strongly to public opinion on the backlash of product INFUSE® for its performance. Initially approved for spinal fusion in 2001, INFUSE® was subsequently approved for tibial fractures in 2004, then for dental operations in 2007. Lawsuits have accused Medtronic of hiding side effects and promoting unapproved use. The decline seen in unit sales in 2013 can be attributed to the controversy and lawsuits surrounding the misuse of INFUSE® for unapproved indications in the spine.


EXECUTIVE SUMMARY
U.S. ORTHOPEDIC BIOMATERIALS MARKET OVERVIEW
COMPETITIVE ANALYSIS
MARKET TRENDS
MARKET DEVELOPMENTS
PROCEDURE NUMBERS
MARKETS INCLUDED
KEY REPORT UPDATES
VERSION HISTORY
RESEARCH METHODOLOGY
1.1 RESEARCH SCOPE
1.2 IDATA’S 9-STEP METHODOLOGY
Step 1: Project Initiation & Team Selection
Step 2: Prepare Data Systems and Perform Secondary Research
Step 3: Preparation for Interviews & Questionnaire Design
Step 4: Performing Primary Research
Step 5: Research Analysis: Establishing Baseline Estimates
Step 6: Market Forecast and Analysis
Step 7: Identify Strategic Opportunities
Step 8: Final Review and Market Release
Step 9: Customer Feedback and Market Monitoring
DISEASE OVERVIEW
2.1 BASIC ANATOMY
2.1.1 Osteology and Musculoskeletal System
2.2 DISEASE PATHOLOGY AND DISORDERS
2.2.1 General Diagnostic
2.2.2 Osteoporosis
2.2.3 Osteoarthritis
2.2.4 Indication for Bone Graft Procedure
2.2.5 Indication for Cartilage Repair
2.2.6 Degenerative Disc Disease
2.3 PATIENT DEMOGRAPHICS
2.3.1 General Statistics
PRODUCT ASSESSMENT
3.1 PRODUCT PORTFOLIOS
3.1.1 Growth Factors
3.1.1.1 Other products
3.2 REGULATORY ISSUES AND RECALLS
3.2.1 Growth Factors
3.3 CLINICAL TRIALS
3.3.1 Growth Factors
ORTHOPEDIC GROWTH FACTOR MARKET
4.1 INTRODUCTION
4.1.1 BMP-2 (Medtronic)
4.1.2 PDGF-BB (Wright Medical)
4.1.3 BMP-7 (Olympus Biomaterials)
4.3 MARKET ANALYSIS AND FORECAST
4.4 DRIVERS AND LIMITERS
4.4.1 Market Drivers
4.4.2 Market Limiters
4.5 COMPETITIVE MARKET SHARE ANALYSIS
ABBREVIATIONS
APPENDIX II: COMPANY PRESS RELEASES
List of Charts
Chart 1 1: Orthopedic Biomaterials Market by Segment, U.S., 2013 – 2023
Chart 1 2: Orthopedic Biomaterials Market Overview, U.S., 2016 & 2023
Chart 4 1: Orthopedic Growth Factor Market, U.S., 2013 – 2023
Chart 4 2: Leading Competitors, Orthopedic Growth Factor Market, U.S., 2016
List of Figures
Figure 1 1: Orthopedic Biomaterials Market Share Ranking by Segment, U.S., 2016 (1 of 2)
Figure 1 2: Orthopedic Biomaterials Market Share Ranking by Segment, U.S., 2016 (2 of 2)
Figure 1 3: Companies Researched in this Report, U.S., 2016
Figure 1 4: Factors Impacting the Orthopedic Biomaterials Market by Segment, U.S. (1 of 2)
Figure 1 5: Factors Impacting the Orthopedic Biomaterials Market by Segment, U.S. (2 of 2)
Figure 1 6: Recent Events in the Orthopedic Biomaterials Market, U.S., 2013 – 2016
Figure 1 7: Orthopedic Biomaterials Markets Covered, U.S., 2016 (1 of 2)
Figure 1 8: Orthopedic Biomaterials Markets Covered, U.S., 2016 (2 of 2)
Figure 1 9: Orthopedic Biomaterials Markets Covered, U.S., 2016(1 of 3)
Figure 3 1: Growth Factors Products by Company
Figure 3 2: Class 2 Device Recall INFUSE(R) Bone Graft
Figure 3 3: Class 2 Device Recall Stryker Biotech
Figure 3 4: A Study of INFUSE Bone Graft (BMP-2) in the Treatment of Tibial Pseudarthrosis in Neurofibromatosis Type 1
Figure 3 5: A Prospective Study of Instrumented, Posterolateral Lumbar Fusions (PLF) With OsteoAMP®
Figure 3 6: The Clinical Effect of i-FACTOR® Versus Allograft in Non-instrumented Posterolateral Spondylodesis Operation
Figure 3 7: Clinical Study of INFUSE® Bone Graft Compared to Autogenous Bone Graft for Vertical Ridge Augmentation
Figure 3 8: RCT of AttraX® Putty vs. Autograft in Instrumented Posterolateral Spinal Fusion (AxA)
Figure 3 9: Clinical Study of Injectable Ceramics Bone Graft Substitute Containing rhBMP-2
Figure 3 10: Prospective Study of Safety and Efficacy of InQu® Bone Graft Extender in Lumbar Interbody Fusion Surgery (Intebody)
Figure 3 11: Long-term Safety and Effectiveness of AUGMENT® Bone Graft Compared to Autologous Bone Graft
Figure 3 12: rhBMP-2 vs Autologous Bone Grafting for the Treatment of Non-union of the Docking Site in Tibial Bone Transport
Figure 3 13: Evaluation of Radiculitis Following Use of Bone Morphogenetic Protein-2 for Interbody Arthrodesis in Spinal Surgery
Figure 4 1: Orthopedic Growth Factor Market, U.S., 2013 – 2023
Figure 4 2: Drivers and Limiters, Orthopedic Growth Factor Market, U.S., 2016
Figure 4 3: Leading Competitors, Orthopedic Growth Factor Market, U.S., 2016
Figure 6 1: Press Release Summary

Download our eBook: How to Succeed Using Market Research

Learn how to effectively navigate the market research process to help guide your organization on the journey to success.

Download eBook

Share this report