Ion Chromatography Market - Segmented by Technology, Application, and Geography - Growth, Trends, and Forecast (2018 - 2023)
The global ion chromatography market was valued at USD 2133.64 million in 2017 and is expected to register a CAGR of 5.76% % over the forecast period. Ion chromatography is a well-established technique for the analysis of anions and cations in liquid, gaseous, and solid samples. Organizations, such as the ISO, US EPA, ASTM, and AOAC have established their standards on regulatory methods of analysis using this technique. Currently, electrochemical and spectrometric methods are two detection methods applied in ion chromatography.
Increasing Use of Ion Chromatography Technique in Purifying Monoclonal Antibodies (mAbs) will boost the Growth of Ion Chromatography Market
Monoclonal antibodies use has increased tremendously over the last decade, and estimates suggest that mAbs and their derivatives account for close to one-third of the biopharmaceuticals under development, including vaccines and gene therapy. Biopharmaceutical products must be pure, as any impurity can significantly affect the body’s response to that particular product and can lead to various unnecessary complications. Typically, this stringent purification is accomplished using a three-column chromatography process. It consists of protein A affinity chromatography process, cation exchange, and anion exchange chromatography. Protein A affinity chromatography is used as an initial capture step due to its high affinity for mAbs. However, protein A affinity chromatography costs higher, and hence, the overall process becomes cost-intensive. Various attempts are being made to make the process cost-effective, and one of the most effective ways of reducing cost significantly is using two-column ion exchange (cation and anion exchange) chromatography. In this, cation-exchange is used as the capture step, and anion exchange as the polishing step. The increasing use of ion exchange chromatography for purification, along with the growing demand for monoclonal antibodies is a primary driver for the ion chromatography market.The other factors, such as increasing academic and commercial R&D spending on pharmaceuticals, increasing use of ion chromatography technique in food, beverage, and water industry, and the technological advancement in ion chromatography are driving this market.
High Cost of Instrument will hinder the Growth of Ion Chromatography Market
High TCO (total cost of ownership) is one of the major restraints the ion chromatography market faces. On an average, any chromatography instrument or system is expected to cost an estimated USD 4000. The cost will increase when the system needs to be customized as per the working environment. The customization includes accessories that need to be purchased with it or customizing its sample handling settings or addition of any other features. The cost of the equipment also depends on the level of accuracy that the organization requires for processing, detection, and analyzing. Dionex ion chromatography systems range between USD 6000 — 10000. New investors and companies looking to expand always consider cost as a crucial factor in taking technology decisions. A new ion chromatography system is a large capital expenditure. It is often considered difficult to obtain budget approvals for large capital expenses. The high cost of the instrument is expected to restrain the ion chromatography market. The other factor, such as lack of skilled personnel to handle the equipment is hindering the market.
Market Segmentation Insights for the Ion Chromatography Market
On the basis of technology it is further divided into Ion-Exchange, Ion-Exclusion and Ion-Pair Chromatography. Ion-exchange Chromatography has the largest share in the market which is about 68% due to the factors like it is cost effective, efficient technique and has a quick separation. Also, Ion exchange is widely used for water treatment in both industrial and municipal water treatment systems that is resulting in the growth of the ion-exchange chromatography segment. However, Ion-exclusion Chromatography is experiencing a rapid growth because of it several advantages such as usage of aqueous acid or base or water with little to no organic modifiers, which is environmentally as well as economically beneficial, and is compatible with aqueous sample matrices. Thus has the highest CAGR during the forecast period.
Insights in the application segment it is further divided into Environmental Testing, Pharmaceutical Industry, Food Industry, Chemicals Industry and others. Environmental Testing has the largest share in the market which is about 29 in the 2017. Factors like ion chromatography is widely used in air purification processes and they also aid in the soil testing process, by accurately determining different elements that are available in soil. It is also used in the field of water pollution. Also, Pharmaceutical industry has the highest CAGR during the forecast period as there is a growing adoption of Ion Chromatography in metabolomics and during the process of drug discovery.
North America is dominating the Ion Chromatography Market
The market is dominated by North America, followed by Europe and Asia-pacific. North America is dominating the market in 2017 which is attributed due to the increasing R&D activities by pharmaceutical and biotechnology companies, growing government initiatives like in the USA many organizations such as USEPA (United States Environmental Protection Agency), ASTM (American Society for Testing and Materials), and AOAC (Association of Official Analytical Chemists) also develop standards or regulatory methods of analysis for applications of ion chromatography. In Canada Ion chromatography is used by ECCC’s (Environment and Climate Change Canada) Laboratory for the analysis of aqueous samples in parts-per-million (ppm) and parts-per-billion (ppb) quantities for anions (chloride, nitrite, nitrate, and sulfate) and cations (sodium, ammonium, and potassium) along with organic acids (oxalate and methanesulfonic acid). Thus all these factors are major factors for the growth of the market in that region.
Key Developments in the Market
- February 2018- New high pressure Ion chromatography system designed to deliver heightened performance by Thermo Fisher.
- December 2017- Thermo Fisher Scientific acquired the Phenom-World.
Major Players -Waters Corporation, Thermo Fisher Scientific, Agilent Technologies, Shimadzu Corporation, GE Healthcare, Tosoh Corporation, Perkin Elmer, Metrohm AG, Mitsubishi Chemical Corporation, and Bio-Rad Laboratories, Inc., among others.
Reasons to Purchase the Report
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