Global Protein Fractionation Market - Growth, Trends and Forecasts (2017 - 2022)
Protein Fractionation Market The market is highly fragmented, with no major players; the fractionation methods are continuously evolving, and there is a continuous demand for better and cost-efficient techniques. Moreover, proteins are the key area of focus for the food, pharmaceutical and diagnostics industries. These industries use protein fractionation for their application in protein-protein interaction studies, drug screening, target identification, biomarker discovery, protein therapeutics, diagnostic tests, and disease monitoring.
Globally, the market for protein fractionation is expected to witness a CAGR of XX% from 2017 to 2022 (forecast period), to be valued at USD XX million in 2017 and reach USD XX million, by 2022.
The key factors driving the protein fractionation market are the increasing expenditure of the pharmaceutical & diagnostic industry and the growing demand for biotechnology-based medicines and protein titers. However, stringent approval policies related with protein therapeutics and high-costs involved with research and development of biotechnology products are restraining the growth of the protein fractionation market.
The protein fractionation market is segmented by the fractionation methodology and chromatographic techniques. Chromatographic techniques have been used since long for purifying, both, native and recombinant proteins. Companies are now investing heavily to improve the already available techniques. Qiagen, Applied Biosystems, and GE Healthcare made many changes to the existing protein fractionation methods, to improve purity, efficiency and ease-of-use. Qiagen has its Two-Step Affinity Purification System, which combines sequential affinity purification steps to yield proteins with more than 98% purity. Doubly tagged recombinant proteins carrying His and Strep tags can be purified by Qiagen's patented nickel-nitrilotriacetic acid (Ni-NTA) resin and Strep-Tactin (a modified streptavidin). BioChrom has also developed a polymeric material, Hydrocell, with polymer beads that are highly cross-linked to enable better and faster protein extraction in comparison to silica-based HPLC columns.
Nowadays, magnetic beads are quite popular for protein purification, due to their speed, ease-of-use and cost efficiency; their popularity can be attributed to the simple purification procedure that does not require any columns or centrifugation. Most of the beads can be used in automated liquid-handling systems. Some companies, such as Dynal Biotech, Polysciences, and Bioscience, have magnetic beads as their flagship product and have a huge capital due to their sales.
North America has the largest market for protein fractionation kits, followed by Europe, owing to the advancement in biotechnology-based therapeutics and the presence of a large number of pharmaceutical companies that are developing new protein molecules. In Asia-Pacific, China, and India are leading the market, due to a high-demand for botanical gene therapies used for making effective herbal medicines. The situation is similar in Brazil, South America.
Some of the major players capturing the protein fractionation market include –
Clontech Thermo Fisher Scientific, Inc. Merck KGaA GE Healthcare Segment-Wise Top Performers Type
Ni Sepharose, HisTrap FF/HP
TALON Metal Affinity
Thermo Fisher / Invitrogen
HisPur Cobalt Resin
Glutathione Sepharose 4B
FLAG M2 Affinity
New England Biolabs
Superdex / Superose / Sephacryl
Ion Exchange Anion
HiTrap Q GE Healthcare
DE52 Anion Exchange Resin
Mono S Column
Phenyl Sepharose CL-4B
Recent Industry Insights
Cancer regulating histone deacetylase proteins fished out using the anti-cancer drug as bait. Abbkine Scientific launched PurKine™ Antibody Purification Protein A Kit. Kamada Ltd., a plasma-derived protein therapeutics company announced a collaboration with Massachusetts General Hospital (MGH). Sanofi, Merck & Co. and downstream technology firm Natrix are working together to develop and enable a fully-integrated downstream platform. Abbkine Scientific launched exclusive Ni-Super Resin product for His-tag Protein Purification. Synthetic Genomics launched Vmax™ Express, a next-generation protein expression platform for the biotech industry. Future Spotlight
The increasing application of biomarker identification will boost the demand for protein fractionation techniques. Future innovations are expected to generate several opportunities for detecting targeted pain receptors, monitoring cellular response and determining genetic predisposition, thus, increasing the requirement for protein fractionation techniques.
Our report on the global protein fractionation market covers the following -
Market trends & dynamics Latest News & protein purification developments Porter’s five forces analysis Investment scope Deep-dive insights