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Adrenal Insufficiency Market Report: 2016 Edition

Adrenal Insufficiency Market Report: 2016 Edition

Adrenal Insufficiency is a rare disease in which the adrenal glands are unable to produce sufficient amount of the hormones cortisone, aldosterone or Dehydroepiandrosterone, which are essential for vital functions of the human body. Cortisol in particular is very important for life and its deficiency can lead to the inability of the body to cope with intense stress. This condition can be life threatening, the sudden and severe worsening of which is called adrenal crisis. Common symptoms of adrenal insufficiency are fatigue, muscle weakness, loss of appetite, weight loss, and abdominal pain.

Adrenal insufficiency can be of two types, namely primary or secondary adrenal insufficiency. Primary adrenal insufficiency, also called Addison’s disease occurs when the adrenal glands cannot produce sufficient amount of the adrenal hormone cortisol or aldosterone. Secondary adrenal insufficiency occurs when the pituitary gland is unable to produce enough amount of adrenocorticotropic hormone (ACTH), the lack of which drops cortisol production resulting in the shrinkage of adrenal glands. The most common cause of adrenal insufficiency is autoimmune diseases like rheumatoid arthritis, pernicious anemia and lupus erythematosus etc., while infections like tuberculosis are also known to cause the disease. It can be diagnosed through tests like Hormonal Blood and Urine Tests.

The entire adrenal insufficiency market can be subdivided into the market for pediatric and adult insufficiency, the latter of which constitutes a massive share. Further, cortisol deficiency records higher prevalence and market among other adrenal hormones. The Adrenal Insufficiency market is characterized by few competitors, specialist providers and known patient groups which are driven by factors like escalating healthcare spending, increasing sales of prescription drugs, rising spending on medicines and growing market for orphan drugs. In recent years, treatment market of this disease has been witnessing increased medical research for alternative therapies like transplantation of adrenal glands. However, symptoms of the disease are often ignored, leaving the market largely underdiagnosed.

The report “Adrenal Insufficiency Market” analyzes the development of this market, with focus on the United States and Europe. Major trends, growth drivers as well as issues being faced by the industry are discussed in detail in the report along with the present and upcoming competition in the market.




























































































1. Market Overview
1.1 Introduction
1.1.1 Cortisol Insufficiency
1.1.2 Aldosterone Insufficiency
1.1.3 Dehydroepiandrosterone Insufficiency
1.2 Symptoms
1.2.1 Adrenal Insufficiency
1.2.2 Adrenal Crisis
1.3 Causes
1.3.1 Primary Adrenal Insufficiency
1.3.2 Secondary Adrenal Insufficiency
1.4 Prevention
1.5 Diagnosis
1.5.1 Hormonal Blood and Urine Tests
1.5.2 Test for Adrenal Crisis
1.6 Treatment Options
2. Global Adrenal Insufficiency Market
2.1 Global Adrenal Insufficiency Prevalence
Table 1: Global Adrenal Insufficiency Prevalence (2015)
2.2 Global Adrenal Insufficiency Market by Value
Table 2: Global Adrenal Insufficiency Market by Value (2015)
2.3 Global Adrenal Insufficiency Prevalence by Type
Table 3: Global Adrenal Insufficiency Prevalence by Type (2015)
2.4 Global Adrenal Insufficiency Market by Region
2.4.1 Global Adrenal Insufficiency Prevalence by Region
Table 4: Adrenal Insufficiency Prevalence by Region (2015)
2.4.2 Global Adrenal Insufficiency Market Value by Region
Table 5: Global Adrenal Insufficiency Market Value by Region (2015)
3. Regional Markets
3.1 The U.S. Cortisol Deficiency Market
3.1.1 Pediatric Cortisol Deficiency Prevalence
Table 6: The U.S. Pediatric Cortisol Deficiency Prevalence (2015)
3.1.2 Pediatric Cortisol Deficiency Market by Value
Table 7: The U.S. Pediatric Cortisol Deficiency Market by Value (2015)
3.1.3 Adult Cortisol Deficiency Prevalence
Table 8: The U.S. Adult Cortisol Deficiency Prevalence (2015)
3.1.4 Adult Cortisol Deficiency Market by Value
Table 9: The U.S. Adult Cortisol Deficiency Market by Value (2015)
3.2 EU5 Cortisol Deficiency Market
3.2.1 Pediatric Cortisol Deficiency Market by Prevalence
Table 10: The EU5 Pediatric Cortisol Deficiency by Prevalence (2015)
3.2.2 Pediatric Cortisol Deficiency Market by Value
Table 11: The EU5 Pediatric Cortisol Deficiency by Value (2015)
3.2.3 Adult Cortisol Deficiency Market by Prevalence
Table 12: The EU5 Adult Cortisol Deficiency by Prevalence (2015)
3.2.4 Adult Cortisol Deficiency Market by Value
Table 13: The EU5 Adult Cortisol Deficiency Market by Value (2015)
4. Market Dynamics
4.1 Growth Drivers
4.1.1 Escalating Healthcare Spending
Table 14: Global Healthcare Spending (2007-2015E)
4.1.2 Increasing Sales of Prescription Drugs
Table 15: Global Sales of Prescription Drugs (2010-2015E)
4.1.3 Rising Incidence of Autoimmune Disease
Table 16: Rheumatoid Arthritis Prevalence in the U.S. (2015-2020E)
4.1.4 Rising Spending on Medicines
Table 17: Global Spending on Medicines (2010-2020E)
4.1.5 Increasing Female Population
Table 18: Global Female Population (2009-2015)
4.1.6 Growing Market for Orphan Drugs
Table 19: Global Orphan Drugs Market (2010-2015E)
4.2 Trends
4.2.1 Oral Glucocorticoid Replacement
4.2.2 Transplantation of Adrenal Glands
4.2.3 Alternate Therapies
4.2.4 Chronic Heroin Dependence as a Cause
4.3 Challenges
4.3.1 Underdiagnosed Disease
4.3.2 Symptoms Often Ignored
5. Competitive Landscape
5.1 Adrenal Insufficiency Upcoming Competition by Sales
Table A: Adrenal Insufficiency Upcoming Competition Sales Comparison (2015)
5.2 Adrenal Insufficiency Market Cap Comparison
Table B: Adrenal Insufficiency Market Cap Comparison (2015)
6. Company Profiles
6.1 Bristol Myers Squibb
6.1.1 Business Overview
Table 20: Bristol Myers Revenue Share by Region (2015)
6.1.2 Financial Overview
Table 21: Bristol Myers Revenue and Net Income (2011-2015)
6.1.3 Business Strategies
6.2 Novartis
6.2.1 Business Overview
Table 22: Novartis Revenue by Business Segments (2015)
Table 23: Novartis Revenue and Net Income (2012-2015)
6.2.3 Business Strategies
6.3 Pfizer Inc.
6.3.1 Business Overview
Table 24: Pfizer Revenue Share by Business Segments (2015)
6.3.2 Financial Overview
Table 25: Pfizer Revenue and Net Income (2011-2015)
6.3.3 Business Strategies
6.4 StrongBridge Biopharma
6.4.1 Business Overview
Table C: StrongBridge Product Portfolio
6.4.2 Financial Overview
Table 26: StrongBridge BioPharma Revenue and Net Income (2018E-2025E)
6.4.3 Business Strategies

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