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The Worldwide Market for Bioreactors: Forecasts to 2019


Attention: There is an updated edition available for this report.

The Worldwide Market for Bioreactors

The essential equipment needed for bioprocessing is the fermenter or bioreactor. Bioreactors are manufactured vessels or systems that support a biologically active environment, as cells require a very specific environment in which to grow. These bioreactors usually range in size from liters to cubic meters, and are often made of stainless steel for the large scale production of therapeutics. In the biopharmaceutical arena, smaller glass bioreactors usually are intended for research work and process development scale-up. Meanwhile, single use bioreactors, also known as disposable bioreactors, have been finding more extensive research and manufacturing use. Bioreactors can operate as batch, fed batch, or continuous stirred-tank reactor systems.

The Worldwide Market for Bioreactors analyzes the current and potential world markets for bioreactors used generally for research and preclinical development applications, and for the manufacture of biopharmaceuticals.

The cost of production can take on a significant role in the pricing of a biologic. Often, the selection of a bioreactor is a critical manufacturing decision. Selection is often done on a case-by-case basis and depends on production requirements. The industry’s turn to single use bioreactors and related technology comes at a time when bioprocessors look to be flexible with production and to minimize costs. The report looks at significant trends in single use bioreactors.

This report offers market forecasts of future growth to 2019. Both single use and stainless steel bioreactor markets are analyzed, with worldwide and geographic forecasts, including the U.S., Europe, Asia, Latin America, and rest of world. The report takes an in-depth look at the market, providing data on the size and growth of the total market as well as of market segments:

  • Single Use Bioreactor Market Share by Type of Molecule, 2014 (monoclonal antibodies, vaccines, gene therapy, recombinant proteins, stem cells, others)
  • World Market for Bioreactors – Single Use Technology, 2014-2019
  • World Market for Bioreactors – Single Use Technology, 2014-2019, by Geographic Segment
  • World Market for Bioreactors – Single Use Technology, 2015, by Geographic Segment
  • Percentage of Marketed Therapeutics by System, 2014
  • Single Use Bioreactor Market Share by Vendor, 2014
  • Single Use Bioreactor Usage by Process, 2014
  • World Market for Bioreactors – Stainless Steel, 2014-2019
  • World Market for Bioreactors – Stainless Steel, 2014-2019, by Geographic Segment
  • World Market for Bioreactors – Stainless Steel, 2015, by Geographic Segment
The Worldwide Market for Bioreactors also reviews the nature and direction of research and trends, and gives insight into some issues facing the industry. The report profiles companies involved in developing and marketing these bioreactors, including:
  • Applikon
  • Danaher-Pall
  • Eppendorf
  • GE Healthcare
  • Thermo Fisher
  • Sartorius
Market forecasts are based on an examination of current market conditions and on investigations into the development of new products by key companies. The market data are generated into multiple year forecasts for different product segments covered in the report. The information presented in this report is the result of data gathered from company product literature and other corporate brochures and documents, as well as information found in the scientific and trade press. In addition, interviews were conducted with company executives and researchers.


  • Executive Summary
    • MARKET OVERVIEW
      • Table Significant Trends in Single Use Bioreactors
      • Table World Market for Bioreactors - Single Use Technology, 2014, 2017, and-2019
      • Table World Market for Bioreactors - Stainless Steel, 2014, 2017, and 2019
    • METHODOLOGY
  • Introduction
    • APERSPECTIVE ON BIOREACTORS
      • The Traditional Model
      • Producing More Product
      • Biosimilar Production
    • BIOREACTOR VARIETY
      • Stainless Steel Units
      • Stirred-Tank Reactors
      • Airlift Fermentors
      • Packed Bed Reactors
      • Hollow-Fiber Reactors
    • SINGLE USE SYSTEMS
      • Single Use Types
      • Single Use Processes
    • ATTRIBUTES OF STAINLESS STEEL AND SINGLE USE BIOREACTORS
      • More Flexibility Needed
      • Mobile and Disposable
        • Table Traditional and Single Use Bioreactor Features
      • Single Use Seamless Transition
    • CHALLENGES FACING ADOPTION OF SINGLE USE BIOREACTORS
    • OPPORTUNITIES FOR SCALE UP
      • Biopharmaceutical Manufacture and Outsourcing
  • Single Use Trends
    • AN ENABLING STRATEGY
    • SINGLE USEMEETING DEMAND
    • GREATER USE IN MICROBIAL CULTURES
    • INCREASING PRODUCT TITER
    • NOVEL TECHNOLOGIES CONTINUE TO EMERGE
    • A CONTINUOUS SCENARIO
    • MODULARITY
  • Corporate Acquisitions
    • DANAHER-PALL-ATMI
    • THERMO FISHER-ADVANCED SCIENTIFICS
    • THERMO FISHER-LIFE TECHNOLOGIES
    • APPLIKON BIOTECHNOLOGY-HALOTEC
    • GE HEALTHCARE-XCELLEREX
    • SARTORIUS-TAP BIOSYSTEMS
    • SARTORIUS-ALLPURE
  • Market Developments
    • ENTRY LEVEL BIOREACTOR
    • NEW 2,000 LITER SINGLE USE BIOREACTOR RUNNING
    • SINGLE USE BIOREACTOR FOR MICROBIAL APPLICATIONS
    • SINGLE-USE FERMENTOR FOR MICROBIAL APPLICATIONS
    • FIRST 2,000 LITER DISPOSABLE BIOREACTOR RUN
    • BIOTECH PORTFOLIO ACQUISITION
    • SARTORIUS' NEW SYSTEMS
    • FUJIFILM INVESTMENTS
    • OPTIMIZE SINGLE USE FACILITIES
    • NEXT GENERATION FACILITY
    • 2,000 LITER INTRODUCTION
    • ACOUSTICWAVE SEPARATION TECHNOLOGY LICENSED
  • Market Perspective
    • FINDING ANICHE
    • IN AN INFLEXIBLE MARKET
      • Change in Product Demand
    • AVOIDING LARGE CAPITAL EXPENDITURES
    • SMALLER BIOPHARMACEUTICAL MARKETS
    • ADDING USERS AND MARKETS
      • Table Single Use Technology Utilization, 2014 and 2018
    • CHANGING MANUFACTURING PROCESSES
      • Market Complexity
      • Need for Commercial Demonstration
      • Impacting Business Strategy
      • Market Opportunities in Perfusion
        • Table Likelihood of Implementing Bioreactor, by Type (2014 data)
    • INNOVATION DRIVING THE MARKET
    • MARKET ANALYSIS AND FORECASTS
      • Single Use Systems
        • Table Drivers of Single Use Bioreactors
        • Table Usage of Disposables in Biopharmaceutical Manufacturing, Any Stage of R&D or Manufacture
        • Table Usage of Disposables in Biopharmaceutical Manufacturing by Stage of Manufacture (R&D through Commercial Manufacture)
        • Table Average Annual Growth Rate, Disposables, 2006-2015
        • Table Single Use Technology Usage, 2014, 2016, and 2018
        • Table Single Use Bioreactor Market Share by Type of Molecule, 2014
        • Table World Market for Bioreactors - Single Use Technology, 2014-2019
        • Table World Market for Bioreactors - Single Use Technology, 2014-2019, by Geographic Segment
        • Table Percentage of Marketed Therapeutics by System, 2014
        • Table Single Use Bioreactor Market Share by Vendor, 2014
        • Table Single Use Bioreactor Usage by Process, 2014
      • Stainless Steel Systems
        • Table World Market for Bioreactors - Stainless Steel, 2014-2019
        • Table World Market for Bioreactors - Stainless Steel, 2014-2019, by Geographic Segment
  • Corporate Profiles
    • APPLIKON BIOTECHNOLOGY
    • BIOENGINEERING AG
    • BROADLEY-JAMES CORP.
    • CELLEXUS LTD.
    • CELLTAINER BIOTECH BV
    • CERCELL APS
    • ELECTROLAB BIOTECH LTD.
    • EPPENDORF
    • FINESSE SOLUTIONS
    • GE HEALTHCARE'S LIFE SCIENCES BUSINESS
    • HEINRICH FRINGS GMBH&CO. KG
    • INFORS AG
    • LIFE TECHNOLOGIES
    • NEW MBR
    • MILLIPORE
    • PALL BIOPHARM
    • PBS BIOTECH INC.
    • PIERRE GUERIN TECHNOLOGIES USINE
    • PLURISTEM THERAPEUTICS INC.
    • SARTORIUS AG
    • TECHNISERV INC.
    • ZETA HOLDING GMBH

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