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In Vitro Toxicology Market

In Vitro Toxicology

In Vitro Toxicology analyses global in vitro toxicity testing markets and various market segments with the objective to identify the important market trends that will bring further growth in this market. The study aims to derive crucial insights that will benefit all the major stakeholders of the industry in developing strategic business plans based on these emerging trends. The report provides market size and growth trends for various toxicity endpoint segments for 2018-2023, including ADME-Tox; cytotoxicity; genotoxicity; ocular toxicity; skin irritation, corrosion, and sensitization; dermal toxicity; carcinogenicity; phototoxicity; neurotoxicity; organ toxicity; and other endpoints and tests.

This report identifies key regional market trends in developed as well as emerging markets, which offer valuable insights to market players including technology companies and contract research organizations who are currently exploring expansion strategies to new geographic markets. The regional market insights are also beneficial for companies in various end-use industry segments to develop market entry strategies as well as outsourcing strategies by understanding the regional market and regulatory trends. In Vitro Toxicology provides market sizing and growth trends for 2018-2023 in North America, Europe, Asia Pacific and rest of world, breaking out this information by technology, by industry, by method and by products and services.

This report also identifies market drivers and restraints to assess how they are shaping the market and its future prospects. In addition, the study identifies major stakeholders and analyses their business strategies with respect to the market segments in which they are active. The report also profiles many leading and niche players of the market, including Charles River Laboratories (CRL), Eurofins Scientific and Thermo Fisher.

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  • Executive Summary
    • Table Market Shares of Regional Market Segments of the In Vitro Toxicity Testing Markets, 2018
    • Table Market Size and Growth Trends of Various Toxicity Endpoint Segments of the Global In Vitro Toxicity Testing Markets (2018-2023) ($ Million)
    • Table Market Shares of Industry Segments of the Global In Vitro Toxicity Testing Markets, 2018
  • Introduction
    • OBJECTIVES OF THE STUDY
    • Market Definition and Scope
      • Markets Covered
    • Research Methodology
  • Market Overview
    • Introduction to In Vitro Toxicity Testing
      • The Concept of 3Rs
        • Table Selected Centers of 3Rs Worldwide
      • The ToxCast and Tox21 Programs, USA
      • AXLR8 Project, Europe
      • DB-ALM, Europe
      • OECD
      • ICH
      • International Cooperation on Cosmetics Regulation (ICCR)
      • International Cooperation on Alternative Test Methods (ICATM)
      • Regulatory Landscape, USA
      • Regulatory Landscape, European Union (EU)
      • Regulatory Landscape, Japan
      • Regulatory Landscape, China
      • Regulatory Landscape, India
        • Table Regulatory Systems and Legislation in India Relevant for In Vitro Toxicity Testing Market
      • Regulatory Landscape, South Korea
        • Table Major Events That Have Shaped the Global In Vitro Toxicity Testing Markets
        • Table In Vitro Toxicity Testing Methods Validated by Regulatory Agencies
    • Industry Trends
      • Rising Innovation Leading to In Vitro Models Closer to Human Systems
      • Emergence of Advanced Technology Platform Companies and Long-Term Partnership Business Models
      • Consolidation of CRO segment in Response to Rising Outsourcing Trends in Pharma Sector
        • Table Examples of Recent M&A Deals in CRO Segment Relevant for In Vitro Toxicity Testing Markets
    • Market Drivers
      • Rising Focus on Alternative Models for Toxicity Testing
      • Increasing Demand for Early Toxicology Testing
      • Ban on Animal Testing in the Cosmetics Industry
      • Regulations and Large-Scale Initiatives by Governments
      • Innovation in Cell Culture Technologies
    • Market Restraints
      • Reluctance of Regulatory Agencies to Consider Alternative Methods
      • Technical Challenges to Develop In Vitro Models That Can Mimic In Vivo Complexities
      • Human Resource Challenges
  • In Vitro Toxicology Testing Market, by Toxicity Endpoints and Tests
    • Introduction
      • Table Global In Vitro Toxicity Testing Market, by Toxicity Endpoints and Tests (2018-2023) ($, Million)
    • ADME-Tox
      • Table Types of Measurements Conducted during In Vitro ADME Screening
      • Solution Properties
      • Absorption and Transport
      • Metabolism
      • Drug-Drug Interactions (DDI)
      • High Throughput ADME Screening
        • Table Selected Companies Active in ADME-Tox Testing and Their Activities
        • Table Markets for In Vitro ADME-Tox Toxicity Testing, by Region (2018-2023) ($, Million)
    • Skin Irritation, Corrosion and Sensitization
      • Skin Irritation
      • Skin Corrosion
      • Skin Sensitization
        • Table Selected Companies Offering In Vitro Skin Irritation, Corrosion and Sensitization Toxicity Testing Products and Services
        • Table Markets for In Vitro Skin Irritation, Corrosion and Sensitization Toxicity Testing, by Region (2018-2023) ($, Million)
    • Genotoxicity
      • Table Regulatory Overview for In Vitro Genotoxicity Testing by US FDA and EMA
      • Table Selected Companies Offering In Vitro Genotoxicity Testing Products and Services
      • Table Markets for In Vitro Genotoxicity Testing, by Region (2018-2023) ($, Million)
    • Cytotoxicity
      • Table Selected Companies Offering In Vitro Cytotoxicity Testing Products and Services
      • Table Markets for In Vitro Cytotoxicity Toxicity Testing, by Region (2018-2023) ($, Million)
    • Ocular Toxicity
      • Ex Vivo Tests
      • In Vitro tests
        • Table 2D and 3D In Vitro Assays Used for Ocular Toxicity Testing
        • Table Selected Companies Offering In Vitro Ocular Toxicity Testing Products and Services
        • Table Markets for In Vitro Ocular Toxicity Testing, by Region (2018-2023) ($, Million)
    • Organ Toxicity
      • Hepatotoxicity
      • Cardiotoxicity
      • Nephrotoxicity
        • Table Selected Companies Offering In Vitro Organ Toxicity Testing Products and Services
        • Table Markets for In Vitro Organ Toxicity Testing, by Region (2018-2023) ($, Million)
    • Phototoxicity
      • Table Selected Companies Offering In Vitro Phototoxicity Testing Products and Services
      • Table Markets for In Vitro Phototoxicity Testing, by Region (2018-2023) ($, Million)
    • Dermal Toxicity
      • Table Selected Companies Offering Products and Services Relevant for In Vitro Dermal Toxicity Testing
      • Table Markets for In Vitro Dermal Toxicity Testing, by Region (2018-2023) ($, Million)
    • Carcinogenicity
      • Table Selected Companies Offering In Vitro Carcinogenicity Testing Products and Services
      • Table Markets for In Vitro Carcinogenicity Toxicity Testing, by Region (2018-2023) ($, Million)
    • Neurotoxicity
      • Table Selected Companies Offering In Vitro Neurotoxicity Testing Products and Services
      • Table Markets for In Vitro Neurotoxicity Testing, by Region (2018-2023) ($, Million)
    • Other Toxicity Endpoints and Tests
      • Endocrine Disruptors
        • Table Laws and Activities Relevant to Endocrine Testing Worldwide
      • Developmental and Reproductive Toxicity (DART)
      • Ecotoxicity
        • Table Selected In Vitro Assays Used for Ecotoxicity Testing
      • Respiratory Toxicity
        • Table In Vitro Models Used in Respiratory Toxicity Testing
        • Table Selected Companies Offering In Vitro Ecotoxicity, Endocrine disruptors, DART and Respiratory Toxicity Testing Products and Services
        • Table Global Demand for Other Toxicity Endpoints and Tests within In Vitro Toxicity Testing Markets, by Region (2018-2023) ($, Million)
  • In Vitro Toxicology Testing Market, by Technology
    • Introduction
      • Table Global In Vitro Toxicity Testing Market, by Technology (2018-2023) ($, Million)
    • Cell Culture Technologies
      • Primary Cells
      • Cell Lines
      • Choosing between Primary and Continuous Cells
        • Table Major Differences between Primary Cells and Continuous Cell Lines
      • Stem Cells
      • Rising Popularity of 3D Cell Cultures
        • Table Major differences between 2D Cell Culture and 3D Cell Culture
        • Table A Comparison of Various 3D Cell Culture Technologies
        • Table 3D Cell Culture Systems on the Market
        • Table Selected Companies Offering Cells and Cell Culture Technologies
      • Recent Innovations in the Cell Culture Technology Segment
        • Table Markets for Cell Culture Technologies for In Vitro Toxicity Testing, by Region (2018-2023) ($, Million)
    • High Throughput Technologies
      • Table Selected Companies Offering High Throughput Technology Based Products and Services for In Vitro Toxicity Testing
      • Table Markets for High Throughput Technologies for In Vitro Toxicity Testing, by Region (2018-2023) ($, Million)
    • Cellular Imaging Technologies
      • 3D Cellular Imaging
      • Current Developments in HCS Markets
        • Table Evolving Capabilities of HCS Systems Enabling New Applications
        • Table Selected Companies Offering Cellular Imaging Technologies for in Vitro Toxicity Testing
        • Table Markets for Cellular Imaging Technologies for In Vitro Toxicity Testing, by Region (2018-2023) ($, Million)
    • Toxicogenomics (TGx)
      • Table Selected Companies Offering Toxicogenomics Technologies for In Vitro Toxicity Testing
      • Table Markets for Toxicogenomics Technologies for In Vitro Toxicity Testing, by Region (2018-2023) ($, Million)
  • In Vitro Toxicology Testing Market, by Industry
    • Introduction
      • Table Global In Vitro Toxicity Testing Market, by Industry (2018-2023) ($, Million)
    • Pharmaceutical Industry
      • Table Markets for In Vitro Toxicity Testing in the Pharmaceutical Industry, by Region (2018-2023) ($, Million)
    • Cosmetics Industry
      • Table Common In Vitro Assays for Testing Various Toxicity Endpoints of Cosmetics Products
      • Table Markets for In Vitro Toxicity Testing in the Cosmetics Industry, by Region (2018-2023) ($, Million)
    • Chemical Industry
      • Table Markets for In Vitro Toxicity Testing in the Chemical Industry, by Region (2018-2023) ($, Million)
    • Others (Food, Medical Devices, etc)
      • Food industry
        • Table Common Toxicity Endpoints and In Vitro Assays Used for Testing Various Food Contact Materials (FCMs)
      • Medical Devices
        • Table In Vitro Toxicity Testing Markets in Other Industry Segments, by Region (2018-2023) ($, Million)
  • In Vitro Toxicology Testing Market, by Method
    • Introduction
      • Table Global In Vitro Toxicity Testing Market, by Method (2018-2023) ($, Million)
    • Biochemical Assays
      • Gene Expression and Protein Secretion Assays
        • Table Selected Companies Offering Biochemical Assays for In Vitro Toxicity Testing
        • Table Markets for Biochemical Assays in In Vitro Toxicity Testing Markets, by Region (2018-2023) ($, Million)
    • 2D Cell-Based Assays
      • Non-Mammalian Cell-based Assays
      • Ames Tests
      • 2D Mammalian Cell-based Assays
      • Sandwich Cultures and Micropatterning
      • Increasing Role of Stem Cell-based Assays in In Vitro Toxicity Testing
        • Table Key Vendors of Commercial iPSCs for In Vitro Toxicity Testing
      • Resurgence of Phenotypic Cell-based Assays in Early Toxicity Testing
        • Table Key Vendors of Phenotypic Cell-based Assays for Early Toxicity Testing
      • Insights on Cell-based Assay Procurement Practices
      • Impact of Regulation on Cell-based Assay Markets
        • Table Cell-based Assays Validated by Regulatory Agencies for Various Toxicity Endpoints
      • 2D Cell-based Assay Market Trends and Forecasts
        • Table Markets for 2D Cell-based Assays within In Vitro Toxicity Testing, by Region (2018-2023) ($, Million)
    • 3D Cell Culture Assays and Ex Vivo Systems
      • Assays Based on Organoids
      • Assays Based on 3D Bioprinting
      • Organ-on-a-Chip Models
        • Table Selected Companies Offering 3D Cell Culture Assays and Ex Vivo Systems for In Vitro Toxicity Testing
        • Table Markets for 3D Cell Culture Assays and Ex Vivo Systems within In Vitro Toxicity Testing, by Region (2018-2023) ($, Million)
  • In Vitro Toxicology Testing Market, by Products and Services
    • Introduction
      • Table Global In Vitro Toxicity Testing Market, by Products and Services (2018-2023) ($, Million)
    • Assays
      • Bacterial Toxicity Assays
        • Table Selected Companies Offering Bacterial Toxicity Testing Products and Services
      • Cell-based ELISA and Western Blots
        • Table Selected Companies Offering Cell-Based ELISAs and Western Blots for In Vitro Toxicity Testing
      • Enzyme Toxicity Assays
        • Table Selected Companies Offering Enzyme Toxicity Assays and Related Services
      • Receptor Binding Assays
        • Table Receptor Binding Assays Validated by Regulatory Agencies
      • Tissue Culture Assays
      • Other Assays
        • Table Selected Companies Offering Tissue Culture Assay Products and Services
        • Table Markets for Various Assays for In Vitro Toxicity Testing, by Region (2018-2023) ($, Million)
    • Reagents and Labware
      • Consumables for Cell Cultures
      • Microplates, Readers, etc.
      • Labware, Instrumentation, and Reagents for HCS
        • Table Selected Companies Offering Reagents and Labware for In Vitro Toxicity Testing
        • Table Markets for Reagents and Labware for In Vitro Toxicity Testing, by Region (2018-2023) ($, Million)
    • Services
      • Table Selected CROs Offering In Vitro Toxicology Testing Services
      • Table Markets for In Vitro Toxicity Testing Services, by Region (2018-2023) ($, Million)
  • In Vitro Toxicology Testing Market, by Region
    • Table Global In Vitro Toxicity Testing Market, by Region (2018-2023) ($, Million)
    • Europe
      • Germany
        • Table Selected Laws Relevant for In Vitro Toxicity Testing Markets in Germany
        • Table Selected Companies Active in the Field of In Vitro Toxicity Testing in Germany
      • The United Kingdom (UK)
        • Table Selected Companies Active in the Field of In Vitro Toxicity Testing in the UK
      • France
        • Table Selected Companies Active in the Field of In Vitro Toxicity Testing in France
      • Italy
        • Table Selected Companies Active in the Field of In Vitro Toxicity Testing in Italy
      • Spain
        • Table Selected Companies Active in the Field of In Vitro Toxicity Testing in Spain
      • Rest of Europe (RoE)
        • Table Selected Companies Active in the Field of In Vitro Toxicity Testing in Rest of Europe
        • Table In Vitro Toxicity Testing Market in Europe, by Products and Services (2018-2023) ($, Million)
        • Table In Vitro Toxicity Testing Markets in Europe: By Toxicity Endpoints (2018-2023) ($, Million)
        • Table In Vitro Toxicity Testing Markets in Europe: By Technology (2018-2023) ($, Million)
        • Table In Vitro Toxicity Testing Markets in Europe: By Method (2018-2023) ($, Million)
        • Table In Vitro Toxicity Testing Markets in Europe: By Industry (2018-2023) ($, Million)
    • North America
      • USA
        • Table Selected Companies Active in the Field of In Vitro Toxicity Testing in the USA
      • Canada
        • Table Selected Companies Active in the Field of In Vitro Toxicity Testing in Canada
        • Table In Vitro Toxicity Testing Markets in North America: By Products and Services (2018-2023) ($, Million)
        • Table In Vitro Toxicity Testing Markets in North America: By Toxicity Endpoints (2018-2023) ($, Million)
        • Table In Vitro Toxicity Testing Markets in North America: By Technology (2018-2023) ($, Million)
        • Table In Vitro Toxicity Testing Markets in North America: By Method (2018-2023) ($, Million)
        • Table In Vitro Toxicity Testing Markets in North America: By Industry (2018-2023) ($, Million)
    • Asia Pacific
      • Japan
        • Table Selected Companies Active in the Field of In Vitro Toxicity Testing in Japan
      • China
        • Table Selected Companies Active in the Field of In Vitro Toxicity Testing in China
      • India
        • Table Selected Companies Active in the Field of In Vitro Toxicity Testing in India
      • Rest of APAC
        • Table In Vitro Toxicity Testing Markets in APAC: By Products and Services (2018-2023) ($, Million)
        • Table In Vitro Toxicity Testing Markets in APAC: By Toxicity Endpoints (2018-2023) ($, Million)
        • Table In Vitro Toxicity Testing Markets in APAC: By Technology (2018-2023) ($, Million)
        • Table In Vitro Toxicity Testing Markets in APAC: By Method (2018-2023) ($, Million)
        • Table In Vitro Toxicity Testing Markets in APAC: By Industry (2018-2023) ($, Million)
  • In Vitro Toxicology Testing Company Profiles
    • BioIVT Group
    • Cell Biolabs, Inc.
    • Charles River Laboratories International, Inc.
    • CiToxLAB Group
    • Covance Inc.
    • Creative Bioarray
    • Cyprotex Plc (currently under Evotec AG)
    • Enzo Life Sciences, Inc. (subsidiary of Enzo Biochem, Inc.)
    • Eurofins Scientific S.E.
    • Gentronix Limited
    • HemoGenix, Inc.
    • MatTek Corporation
    • MB Research Laboratories
    • MIMETAS B.V.
    • Organovo Holdings, Inc.
    • Thermo Fisher Scientific Inc.
    • TissUse GmbH
    • Xenometrix AG
  • Company Names & Addresses
    • Company Names & Addresses
      • 3D Biotek, LLC
      • 3Dynamic Systems Ltd
      • Absorption Systems
      • Abzena
      • Across Barriers GmbH
      • Admescope Ltd
      • Agilent Technologies
      • Albany Molecular Research Inc. (AMRI)
      • Alcyomics Ltd
      • AllCells, LLC
      • Alternative Toxicity Services
      • American Type Culture Collection (ATCC)
      • An-eX analytical services ltd
      • Anthem BioSciences
      • Applied Genetics Laboratories, Inc.
      • APSciences
      • Ascendance Biotechnology (formerly Hepregen Corporation)
      • AseaCyte Sdn Bhd
      • Asinex Ltd
      • Aspect Biosystems
      • Aurigene Discovery Technologies Limited
      • AvantiCell
      • Bio TeSys GmbH
      • Bioalternatives SAS
      • BioIVT
      • Bioneeds India Private Limited
      • biopta (Group of Reprocell Europe)
      • Bio-Rad Laboratories, Inc.
      • BioReliance Corporation
      • Bioscience Laboratories
      • BioScreen Testing Services, Inc.
      • BioSeek Inc.
      • BioStatus
      • BioTalentum Ltd
      • BioTek Instruments, Inc.
      • Catalent Pharma Solutions
      • CellSystems Biotechnologie Vertrieb GmbH
      • Celther Poland
      • Charles River Laboratories International Inc.
      • ChemDiv
      • ChemPartner
      • ClinWorld (P) Ltd
      • CN Bio Innovations Limited
      • Concord Biosciences LLC
      • Corning
      • Covance, Inc. (a part of Laboratory Corporation of America Holdings)
      • Creative Animodel
      • Creative Bioarray
      • Creative Biolabs
      • Crown Bioscience Inc.
      • Cultex Laboratories GmbH
      • Cyfuse Biomedical K.K
      • Cyprotex PLC (a subsidiary of Evotec Ag)
      • Cytox
      • Dermal Technology Laboratory Ltd
      • ebpi (environmental bio-detection products inc)
      • Empiriko Corporation
      • Emulate, Inc.
      • Enmine LLC
      • Envigo RMS, Inc.
      • Epithelix Sàrl
      • Evercyte GmbH
      • GE Healthcare
      • Gentronix Limited
      • GLR Laboratories Pvt Ltd
      • GVK Biosciences Private Limited
      • Hìrel Corporation
      • HCS Pharma
      • HD Biosciences
      • Helix3inc
      • HemoGenix, Inc.
      • Hutchison Medi Pharma
      • ImQuest BioSciences
      • In Vitro International (IVRO)
      • INDIGO Biosciences, Inc.
      • InSphero AG
      • Institute for In Vitro Sciences, Inc. (IIVS)
      • Intertek
      • Invitrocue Limited
      • Jai Research Foundation
      • Joinn Laboratories
      • Jubilant Biosys Limited
      • Kirkstall, Ltd
      • KIYATEC
      • LAUS Corp
      • Life Chemicals USA, Inc.
      • Lonza Group Ltd
      • L'Oréal International
      • Marin Biologic Laboratories
      • MatTek Corporation
      • MB Research Laboratories
      • Medicilon
      • Merck KGaA
      • Microbac Laboratories, Inc.
      • Mimetas B.V.
      • MR Research Laboratory
      • Nano3D Biosciences, Inc.
      • NOF America Corp
      • Olympus
      • ORGANOGENIX, Inc.
      • Organovo Holdings Inc.
      • Oroxcell SAS
      • OxSyBio
      • Pacific BioLabs
      • PerkinElmer
      • Pharmaron Beijing Co., Ltd
      • Promega Corporation
      • Puracyp, Inc.
      • Qgel SA
      • regenHu Ltd
      • ReproCELL Europe Ltd
      • RTC - Research Toxicology Centre
      • Sai Life Science Ltd
      • Sanofi Pasteur VaxDesign Campus
      • Sekisui Xeno Tech, LLC
      • SenzaGen AB
      • SGS SA
      • STEMCELL Technologies
      • Sundia Meditech
      • Syngene International Ltd
      • Synthecon
      • TCG Life Science (Chembiotek)
      • Thermo Fisher Scientific
      • TissUse GmbH
      • Trevigen
      • Vanta Bioscience Limited
      • Vimta Labs
      • Vipragen Biosciences Private Limited
      • Vitro Biopharma
      • VitroScreen S.r.L.
      • Viva Biotech Ltd
      • Vivo Bio Tech Ltd
      • Vivotecnia Research
      • WuXi AppTec
      • Xenometrix AG
      • Zyleris Pharmatech, Inc.
  • Glossary
    • Table Glossary

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