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The World Market for Neurotherapeutic Drugs

Management of both acute and chronic neurologic diseases can be challenging for both the patient and the health care provider. Many neurologic disorders involve progressive deterioration in physical and mental capabilities, which can be devastating to the patient and the patient’s family. In many respects, neurotherapeutics represent the largest as-yet untapped market in medicine.

This Kalorama Information report focuses on several key product segments of neurotherapeutic treatment:

  • Alzheimer’s Disease and Other Dementias
  • Brain and Neurologic Cancers
  • Brain Trauma and Stroke
  • Movement Disorders
  • Seizure Disorders and Epilepsy
  • Spinal Cord and Peripheral Nerve Disorders
  • Other Neurological Conditions and Disorders

The report covers both currently marketed and late-stage development neurotherapeutic products in detail. Revenues for each segment were generated using dollar and unit sales for each product.

The report includes statistical information for selected neurological conditions and diseases by type worldwide, with special emphasis on the U.S. market. The market segments provide an overview, description of products on the market, description of products in development, market estimates and forecasts, and competitive analysis of leading providers. The report also includes current issues and trends affecting the industry.

The information for this report was gathered using both primary and secondary research including comprehensive research of secondary sources such as company literature, databases, investment reports, and medical and business journals. Telephone interviews and email correspondence were the primary method of gathering information. For the purpose of this study Kalorama Information conducted interviews with key industry officials, consultants, health care providers, and government personnel. These sources were the primary basis in gathering information specifically relating to revenue and market share data presented in this report. Specific interviews with pharmaceutical company representatives included marketing directors, division managers, and product representatives.

All market data pertain to the world market at the manufacturers’ level. The base year for data was 2004. Historical data are provided for the years 2002 and 2003, with forecast data provided for 2005 through 2009. Compound annual growth rates (CAGRs) are provided for the 2002-2004, 2004-2009 and 2002-2009 periods for each industry segment covered. Competitive analysis is provided for the year 2004. The forecasted market analysis for 2005-2009 was based on probability of approval and sales of products in late stage development, product marketing, and demographic trends.

Diseases addressed in this study include:

  • Alzheimer’s Disease
  • Amyotrophic Lateral Sclerosis
  • Bell’s Palsy
  • Traumatic Brain Injury (TBI)
  • Brain and Spinal Tumors
  • Carpal Tunnel Syndrome
  • Cerebral Palsy
  • Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
  • Creutzfeldt-Jakob Disease
  • Epilepsy
  • Guillain-Barre Syndrome
  • Huntington’s Disease
  • Migraine Headaches
  • Motor Neuron Diseases
  • Multi-Infarct Dementia
  • Multiple Sclerosis
  • Myasthenia Gravis
  • Neurofibromatosis
  • Parkinson’s Disease
  • Spinal Cord Injury
  • Stroke


  • Executive Summary
    • INTRODUCTION
    • SCOPE AND METHODOLOGY
    • SIZE AND GROWTH OF THE MARKET
      • Table The World Market for Neurotherapeutic Drugs 2002-2009
      • Table Compound Annual Growth Rate
    • ISSUES AND TRENDS AFFECTING MARKET
    • LEADING COMPETITORS
  • Introduction
    • STRUCTURAL ORGANIZATION OF THE NEUROLOGICAL SYSTEM
      • Central Nervous System
      • Peripheral Nervous System
      • Autonomic Nervous System
      • Neurons and Supportive Cells
      • Neurotransmitters
    • AGING
    • TYPES OF NEUROLOGICAL DISEASES AND DISORDERS
      • Table Neurologic Conditions and Diseases by Chapter in This Study
    • DEMOGRAPHICS AND STATISTICS
      • Table Estimated World Prevalence, Incidence and Mortality of Selected Neurological Conditions and Diseases
      • Table World Population by Selected Geographical Region (Africa, Asia, Europe, North America, Oceania, South America) 2004–2050
      • Table Estimated World Population by Age and Geographical Region, 2004
  • Alzheimer's Disease and Other Dementias
    • OVERVIEW
    • DESCRIPTION OF PRODUCTS
      • Acetylcholinesterase Inhibitors
      • N-Methyl-D-aspartate (NMDA)
      • Nootropic Drugs
        • Table Currently Available Alzheimer's's Disease and Dementia Treatments (Type, Brand, and Manufacturer)
    • RESEARCH AND DEVELOPMENT
      • Table Alzheimer's Disease and Other Dementia Therapies in Development
    • MARKET SIZE AND GROWTH
      • Table The World Market for Alzheimer's Disease and Other Dementias 2002-2009
      • Table Compound Annual Growth Rate
      • Table Alzheimer's Disease and Other Dementias Market Estimated Products Sales by Geographic Region, 2004
      • COMPETITIVE ANALYSIS
        • Table Alzheimer's Disease and Other Dementias Market Estimated Revenues and Market Share of Leading Suppliers 2004
        • Table Alzheimer's Disease and Other Dementias Market Estimated Sales and Market Share of Top Products 2004
  • Brain and Neurologic Cancers
    • OVERVIEW
    • DESCRIPTION OF PRODUCTS
      • Table Currently Available Brain and Neurologic Cancer Treatments (Type, Brand, and Manufacturer)
    • RESEARCH AND DEVELOPMENT
      • Table Brain and Neurologic Cancer Treatments in Development
    • MARKET SIZE AND GROWTH
      • Table The Market for Brain and Neurologic Cancer Treatments 2002-2009
      • Table Compound Annual Growth Rate
      • Table Brain and Neurologic Cancer Treatments Market Estimated Products Sales by Geographic Region, 2004
    • COMPETITIVE ANALYSIS
      • Table Brain and Neurologic Cancer Treatments Market Estimated Revenues and Market Share of Leading Suppliers 2004
      • Table Brain and Neurologic Cancer Treatments Market Estimated Sales and Market Share of Top Products 2004
  • Brain Trauma and Stroke
    • OVERVIEW
      • Traumatic Brain Injury
      • Cerebrovascular Disease and Stroke
    • DESCRIPTION OF PRODUCTS
      • Table Currently Available Brain Trauma and Stroke Treatments (Type, Brand, and Manufacturer)
    • RESEARCH AND DEVELOPMENT
      • Table Brain Trauma and Stroke Treatments in Development
    • MARKET SIZE AND GROWTH
      • Table The Market for Brain Trauma and Stroke Treatments 2002-2009
      • Table Compound Annual Growth Rate
      • Table Brain Trauma and Stroke Treatments Market Estimated Products Sales by Geographic Region, 2004
    • COMPETITIVE ANALYSIS
      • Table Brain Trauma and Stroke Treatments Market Estimated Revenues and Market Share of Leading Suppliers 2004
  • Movement Disorders
    • OVERVIEW
      • Parkinson's Disease
      • Huntington's Disease
      • Myasthenia Gravis
      • Tic and Tourette's Syndrome
      • Periodic Limb Movement Disorder and Restless Leg Syndrome
    • DESCRIPTION OF PRODUCTS
      • Anticholinergic Agents
      • Catechol-O-Methyltransferase Inhibitors
      • Dopaminergic Agents
      • Monoamine Oxidase Inhibitor
    • Others
      • Table Currently Available Movement Disorder Treatments (Type, Brand, and Manufacturer)
    • RESEARCH AND DEVELOPMENT
      • Table Movement Disorder Treatments in Development
    • MARKET SIZE AND GROWTH
      • Table The Market for Movement Disorders 2002-2009
      • Table MARKET SIZE AND GROWTH
      • Table Movement Disorder Market Estimated Products Sales by Geographic Region, 2004
    • COMPETITIVE ANALYSIS
      • Table Movement Disorder Market Estimated Revenues and Market Share of Leading Suppliers 2004
      • Table Movement Disorder Market Estimated Sales of Top Products 2004
  • Seizure Disorders and Epilepsy
    • OVERVIEW
      • Generalized Seizures
      • Partial Seizures
      • Aura/Prodrome
    • DESCRIPTION OF PRODUCTS
      • Barbiturates
      • Benzodiazepines
      • GABA analogues
      • Hydantoins
      • Miscellaneous
      • Phenyltriazines
      • Succinimides
        • Table Currently Available Seizure Disorders and Epilepsy Treatments (Type, Brand, and Manufacturer)
    • RESEARCH AND DEVELOPMENT
      • Table Seizure Disorders and Epilepsy Treatments in Development
    • MARKET SIZE AND GROWTH
      • Table The Market for Seizure Disorders and Epilepsy 2002-2009
      • Table MARKET SIZE AND GROWTH
      • Table Seizure Disorders and Epilepsy Market Estimated Products Sales by Geographic Region, 2004
    • COMPETITIVE ANALYSIS
      • Table Seizure Disorders and Epilepsy Market Estimated Revenues and Market Share of Leading Suppliers 2004
      • Table Seizure Disorders and Epilepsy Market Estimated Sales of Top Products 2004
  • Spinal Cord and Peripheral Nerve Disorders
    • OVERVIEW
      • Multiple Sclerosis
      • Amyotrophic Lateral Sclerosis
      • Spinal Cord Injury
      • Guillian-Barre Syndrome
      • Bell's Palsy
    • DESCRIPTION OF PRODUCTS
      • Table Currently Available Spinal Cord and Peripheral Nerve Disorder Treatments (Type, Brand, and Manufacturer)
    • RESEARCH AND DEVELOPMENT
      • Table Spinal Cord and Peripheral Nerve Disorder Treatments in Development
    • MARKET SIZE AND GROWTH
      • Table The Market for Spinal Cord and Peripheral Nerve Disorders 2002-2009
      • Table MARKET SIZE AND GROWTH
      • Table Spinal Cord and Peripheral Nerve Disorder Market Estimated Products Sales by Geographic Region, 2004
    • COMPETITIVE ANALYSIS
      • Table Spinal Cord and Peripheral Nerve Disorder Market Estimated Revenues and Market Share of Leading Suppliers 2004
      • Table Spinal Cord and Peripheral Nerve Disorder Market Estimated Sales of Top Products 2004
  • Other Neurological Conditions and Diseases
    • OVERVIEW
      • Migraine Headaches
      • Neurofibromatosis
      • Neuropathies
      • Trigeminal Neuralgia
      • Postherpetic Neuralgia
    • DESCRIPTION OF PRODUCTS
      • Serotonin Receptor Agonists
      • Ergot Alkaloids
      • Beta Andrenergic Blocking Agents
      • Isometheptene & Others
        • Table Currently Available Other Neurological Conditions and Disorders Treatments (Type, Brand, and Manufacturer)
    • RESEARCH AND DEVELOPMENT
      • Table Other Neurological Conditions and Disorders Treatments in Development
    • MARKET SIZE AND GROWTH
      • Table The Market for Other Neurological Conditions and Disorders 2002-2009
      • Table MARKET SIZE AND GROWTH
      • Table Other Neurological Conditions and Disorders Market Estimated Products Sales by Geographic Region, 2004
    • COMPETITIVE ANALYSIS
      • Table Other Neurological Conditions and Disorders Market Estimated Revenues and Market Share of Leading Suppliers 2004
      • Table Other Neurological Conditions and Disorders Market Estimated Sales of Top Products 2004
  • Issues and Trends Affecting the Neurotherapeutic Drug Market
    • INTRODUCTION
    • DISEASE MODIFYING AGENTS
    • STEM CELL RESEARCH AND NEUROLOGICAL DISEASES
    • BIOMARKERS
    • EARLY DIAGNOSIS
    • ESTROGEN AND COGNITIVE FUNCTION
    • CHOLESTEROL AND ALZHEIMER'S DISEASE
    • NERVE GROWTH FACTOR GENE THERAPY
    • INDIVIDUALIZED TREATMENT
    • VITAMIN ROLE IN ALZHEIMER'S DISEASE
    • MANAGEMENT OF BRAIN TUMORS
    • GENETIC THERAPY
    • ALZHEIMER'S PREVENTION INITIATIVE
  • Market Summary
    • OVERVIEW
    • TOTAL MARKET SIZE AND FORECAST
      • Table The World Market for Neurotherapeutic Drugs 2002-2009
      • Table TOTAL MARKET SIZE AND FORECAST
      • Table Worldwide Neurotherapeutic Drug Market by Type 2002-2009
      • Table TOTAL MARKET SIZE AND FORECAST
  • Corporate Profiles
    • INTRODUCTION
    • ABBOTT LABORATORIES
    • ASTRAZENECA PLC
    • BIOGEN IDEC, INC.
    • BOEHRINGER INGELHEIM GMBH
    • BRISTOL-MYERS SQUIBB COMPANY
    • EISAI, INC
    • GLAXOSMITHKLINE
    • JOHNSON & JOHNSON GROUP
    • MERCK & COMPANY, INC.
    • NOVARTIS PHARMACEUTICALS CORPORATION
    • PFIZER, INC.
    • ROCHE
    • SANOFI-AVENTIS
    • SCHERING AG
    • SCHERING-PLOUGH CORPORATION
    • SERONO
    • TEVA
  • Company Directory

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