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Growth Factors: Indications, Products, and Markets

Growth factors are gene products that play important roles in the regulation of cell division and tissue proliferation. Generally, the binding of a growth factor to its receptor initiates or, in some cases, blocks the ability of cells to divide and multiply. The nature and mode of action of these substances have made them of great interest in various therapeutic areas for which efficacy and specificity must go hand in hand.

This report analyzes the world markets for growth factors, focusing on the current and future markets for drugs used to promote the growth of tissue, organs, and blood vessels as well as those used in adjunctive cancer therapy, hepatitis C, and other indications.

Market forecasts are based on an examination of current market conditions and on investigations into the development of new products by key companies. This information is also weighted with the projected timing and the probability of receiving FDA and other regulatory approval to market products. Data points include estimates of global market size and growth for blood and tissue growth factors; competitive market share for categories such as erythropoietins, colony-stimulating factors, interleukins, interferons, wound growth factors, and neurotrophic growth factors; and geographic breakdown for four world regions.

In addition, the report generally reviews the nature and direction of research and profiles several companies involved in marketing or developing such products in the field, including Amgen, Chiron, Genentech, Johnson and Johnson, Stryker Biotech, and Wyeth, among others.

Interviews conducted with company executives, clinicians, researchers, and public health officials form the basis of the conclusions. In addition, information was gathered from company product literature and other corporate brochures and documents, as well as information found in the scientific literature, trade press, government databases, and regulatory filings.


  • Executive Summary
    • Growth Factor Types
      • Blood Growth Factors
      • Tissue Growth Factors
    • Key Established Indications
      • Blood Growth Factors
      • Tissue Growth Factors
    • Key Emerging Indications For Growth Factors
      • Tissue Growth Factors
    • Major Market Players
      • Blood Growth Factors
      • Tissue Growth Factors
    • Issues Driving The Market
    • Worldwide Market Forecast Summary
      • Blood Growth Factors
        • Table World Market For Blood Growth Factors By Segment 2003 & 2007
      • Tissue Growth Factors
        • Table World Market For Tissue Growth Factors 2003, 2004, 2007
    • Scope And Methodology
  • Introduction
    • The Need For Growth Factors
    • Growth Factors Defined
    • Blood Growth Factors
      • Erythropoietins
      • Colony Stimulating Growth Factors
      • The Interleukins
      • The Interferons
    • Tissue Growth Factors
      • Wound Healing Growth Factors
      • Platelet Derived Growth Factor
      • Keratocyte Growth Factor
      • Epidermal Growth Factor
      • Vascular Endothelial Growth Factor
      • Neurotrophic Growth Factors
      • Fibroblast Growth Factors
      • Insulin-Like Growth Factor
      • Musculoskeletal And Connective Tissue Growth Factors
    • Market Drivers
      • Population Growing
      • Potential For Serious Disease Increases
        • Table World Population Distribution By General Age Group 1996, 2001, 2006, 2025, 2050
      • Epidemiologic Data And Demand Analysis
        • Table Cancer Incidence And Deaths As a Percentage To Population By Selected Country/Region, 2001
        • Table Global And U.S. Yearly Incidence Of Skin Ulcers By Type
      • Tissue Engineering
    • Challenges Facing Developers
      • Biologics Issues Hurdle
      • Importance Of Process Control
  • Research Trends
    • In The Pipeline
      • Table Selected Developmental Growth Factor-Based Therapies - Part 1
      • Table Selected Developmental Growth Factor-Based Therapies - Part 2
    • Specific Research Highlights
      • Blood Vessel Growth
      • Blood Vessel Cells
      • Cartilage Formation
      • Disease-Fighting Cells
      • Skin Treatment
      • Stroke Therapy
      • Sarcopenia
      • Parkinson's Disease
  • The Market
    • Overall Forecasts And Trends
      • Table World Market For Growth Factor Therapeutics Blood Growth Factors 2003-2007
      • Table World Market For Growth Factor Therapeutics Tissue Growth Factors 2003-2007
    • Products On The Market
      • Table Growth Factor-Based Therapies On The Market - Part 1
      • Table Growth Factor-Based Therapies On The Market - Part 2
      • Research Products
    • Market Players And Product Share
      • Erythropoietins
        • Table Market Share For Leading Growth Factor Therapeutics Erythropoietins 2003
      • Colony Stimulating Factors
        • Table Market Share For Leading Growth Factor Therapeutics Colony Stimulating Factors 2003
      • Interleukins
        • Table Market Share For Leading Growth Factor Therapeutics Interleukins 2003
      • Interferons
        • Table Market Share For Leading Growth Factor Therapeutics Interferons 2003
      • Wound Growth Factors
        • Table Market Share For Leading Growth Factor Therapeutics Wound Care Growth Factors 2005
      • Neurotrophic Growth Factors
        • Table Market Share For Leading Growth Factor Therapeutics Neurotrophic Growth Factors 2005
    • Worldwide Market Forecast For Growth Factors
      • Established Blood Growth Factor Markets
        • Table Total World Market For Blood Growth Factors 2003-2007
        • Table World Market For Blood Growth Factors Distribution Of Revenues By Factor Type 2003-2007
        • Table World Market For Erythropoietins 2003-2007
        • Table World Market For Colony Stimulating Factors 2003-2007
        • Table World Market For Interleukins 2003-2007
        • Table World Market For Interferons 2003-2007
      • Established Tissue Growth Factor Markets
        • Table Total World Market For Tissue Growth Factors 2003-2007
        • Table World Market For Tissue Growth Factors Distribution Of Revenues By Factor Type, 2003-2007
        • Table World Market For Wound Growth Factors 2003-2007
        • Table World Market For Neurotrophic Growth Factors 2003-2007
      • Geographical Forecasts
        • Table The Market For Erythropoietins By Geographical Region 2003-2007
        • Table The Market For Colony Stimulating Factors By Geographical Region 2003-2007
        • Table The Market For Interleukins By Geographical Region 2003-2007
        • Table The Market For Interferons By Geographical Region 2003-2007
        • Table The Market For Wound Growth Factors By Geographical Region 2003-2007
        • Table The Market For Neurotrophic Growth Factors By Geographical Region 2003-2007
  • Company Profiles
    • Table Advanced Tissue Sciences
    • Table Amgen Inc.
    • Table Anika Therapeutics Inc.
    • Table Biomimetic Pharmaceuticals Inc.
    • Table Biosurface Engineering Technologies Inc.
    • Table Boston Life Sciences Inc.
    • Table Ceregene Inc.
    • Table Chiron Corp.
    • Table Curagen Corp.
    • Table Curis Inc.
    • Table Eyetech Pharmaceuticals Inc
    • Table Fibrogen Inc.
    • Table Genentech Inc.
    • Table Gensci Regeneration Sciences Inc.
    • Table Genvec Inc.
    • Table Human Genome Sciences
    • Table Insmed Inc.
    • Table Johnson & Johnson
    • Table Orquest Inc.
    • Table Protein Polymer Technology Inc.
    • Table Regeneron Pharmaceuticals Inc.
    • Table Sangamo Biosciences Inc.
    • Table Selective Genetics Inc.
    • Table Spectrum Pharmaceuticals Inc.
    • Table Stryker Biotech
    • Table Theratechnologies
    • Table Transition Therapeutics Inc.
    • Table Wyeth
    • Table Zymogenetics Inc.
  • Company Directory

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