Market Research Logo

Global Cell Culture Markets (Media, Sera, Reagents)

Global Cell Culture Markets (Media, Sera, Reagents)

Growth in the use of cell culture for biological research, vaccine production, the production of therapeutic proteins, and emerging regenerative medicine applications are driving the global cell culture market. As second generation biologics such as monoclonal antibodies replace first generation therapeutic proteins, there is also an increased demand for more advanced in vitro cell culture techniques with greater growing capacities. This report is focused on cell culture used in the research and production of biopharmaceuticals, which includes stem cell therapeutics. Worldwide demand for cell culture products for use in the research, development, and production of biotherapeutic drugs is forecast to expand during the forecast period. Market data provided in Global Cell Culture Markets include:

  • Global Cell Culture Market, 2012-2022 (mil US$)
  • Global Cell Culture Market by Segment, 2012–2022 (mil US$) (Media, Sera, Reagents, Total)
  • Global Cell Culture Market by Region/Country, 2017 (North America, Europe, UK/Ireland, Singapore/Malaysia, Japan, Korea, China, Rest of World)
  • Global Cell Culture Market by Region/Country, 2022 (North America, Europe, UK/Ireland, Singapore/Malaysia, Japan, Korea, China, Rest of World)
  • Cell Culture Market Share by Company, 2017
Media Market

The most significant recent trend in media is a shift from serum- and animal-component-containing media to serum-free and chemically defined media. Prior to 2000, cell culture media usually contained serum, which includes undefined growth promoting factors. The report provides the following media market data:
  • Global Cell Culture Media Market, 2012 – 2022 (mil US$)
  • Global Cell Culture Media Market by Type, 2017 (%) (Serum-Free, Chemically Defined, Animal-Free)
  • Global Cell Culture Media Market by Type, 2022 (%) (Serum-Free, Chemically Defined, Animal-Free)
Sera Market

Serum has traditionally been used as the major supplement to cell culture media. Serum is a complex mix of albumins, growth factors, and growth inhibitors. Serum is one of the most important components of cell culture media and serves as a source for amino acids, proteins, vitamins (particularly fat-soluble vitamins such as A, D, E, and K), carbohydrates, lipids, hormones, growth factors, minerals, and trace elements. The most commonly used types are from fetal and calf bovine sources. The report provides the following sera market data:
  • Global Cell Culture Sera Market, 2012–2022 (mil US$)
  • Global Cell Culture Sera by Type, 2017 (%) (Serum-Free, Chemically Defined, Animal-Free)
  • Global Cell Culture Sera by Type, 2022 (%) (Serum-Free, Chemically Defined, Animal-Free)
Reagent Market

The reagents segment of the cell culture market is driven by their increasing use in biotherapeutics research and production. Companies and research laboratories that work with cell culture want to grow cells cost efficiently and at the same levels as is possible with serum supplementation. Typically, this requires the addition of growth factors, lipids, substitutes for transferrin and albumin, compounds capable of detoxification, and specific attachment factors. The report provides the following reagent market data:
  • Global Cell Culture Reagent Market, 2012 – 2022 (mil US$)
  • Global Cell Culture Reagent Market by Type, 2017 (%) (Cytokines & Growth Factors, Cell Dissociation Reagents, Buffers and Salt Solutions, Other Reagents)
  • Global Cell Culture Reagent Market by Type, 2022 (%) (Cytokines & Growth Factors, Cell Dissociation Reagents, Buffers and Salt Solutions, Other Reagents)
Biopharmaceuticals

Biopharmaceuticals may increase life expectancy, decrease disability, and reduce the need for health services. The approved drugs include hormones, blood factors, thrombolytics, vaccines, interferons, mAbs, and therapeutic enzymes. In the pharmaceutical industry, cell culture is a major foundation of biopharmaceutical development, bioprocessing, and manufacturing. As growing cells for biopharmaceutical production is slow, expensive, and complicated, optimizing cell culture development is of paramount concern to companies developing biopharmaceuticals. Global Cell Culture Markets notes the top selling biopharmaceuticals in 2015, 2016, and 2017; FDA-approved biopharmaceuticals in 2015, 2016, and 2017; and biosimilars approved for human use in the US.

Company Profiles

In a market characterized by a high level of concentration, cell culture product suppliers can increase market share and sustain margins by partnering with pharmaceutical companies, or by acquiring smaller producers or companies that manufacture specialty products. The report profiles the major concerns in the cell culture market, including:
  • Analytical Biological Services Incorporated
  • Athena Enzyme Systems
  • Avantor Incorporated
  • BD Biosciences
  • Bio-Techne Corporation
  • BioreclamationIVT LLC
  • Cell Essentials Incorporated
  • CellGenix GmbH
  • Corning Life Sciences
  • GE Healthcare Life Sciences
  • Gemini Bio-Products
  • InVitria
  • Irvine Scientific Sales Company Incorporated
  • Kohjin Bio Company Limited
  • Lonza Group Limited
  • MilliporeSigma
  • MP Biomedicals LLC
  • Nissui Pharmaceutical Company Limited
  • PromoCell GmbH
  • Quality Biological Incorporated
  • SBH Sciences Incorporated
  • ScienCell Research Laboratories Incorporated
  • Selexis SA
  • Serana Europe GmbH
  • STEMCELL Technologies Incorporated
  • Takara Bio Incorporated
  • Thermo Fisher Scientific Incorporated
  • Wisent Incorporated
Cell culture products used in diagnostics are excluded from the scope of this study. The information for this report was gathered using both primary and secondary research, including comprehensive research of secondary sources such as company literature, databases, investment reports, and medical and business journals. Telephone interviews and email correspondence were the primary methods of gaining information. For the purpose of this study, Kalorama Information conducted interviews with key industry officials, consultants, and government personnel. These sources were the primary basis in gathering information specifically relating to revenue and market share data presented in this report. Pharmaceutical company and cell culture supply company representatives interviewed included marketing directors, division managers, and product representatives.


  • Executive Summary
    • Biopharmaceuticals Primary Driver of Cell Culture Market
    • Cell Culture Reagents Will Offer the Best Opportunities Through 2022
    • The Asia/Pacific Region Is Expected to Post the Fastest Growth
    • Scope and Methodology
  • Biopharmaceuticals
    • Growth in Biopharmaceutical Production Boosts Demand for Cell Culture Products
    • Introduction to Biopharmaceuticals
      • Table Selected Biopharmaceuticals Produced from Bacteria, Yeast, and Mammalian Cells
    • Global Biopharmaceutical Market
    • Top Selling Biopharmaceuticals in 2015, 2016, and 2017
      • Table Top Selling Biological Drugs in 2015
      • Table Top Selling Biological Drugs in 2016
      • Table Top Selling Biological Drugs in 2017
    • FDA-Approved Biopharmaceuticals
      • Table FDA Biopharmaceutical Product Approvals, 2015
      • Table FDA Biopharmaceutical Product Approvals, 2016
      • Table FDA Biopharmaceutical Product Approvals, 2017
    • Biosimilars
      • Table Biosimilars Approved for Human Use in the US
    • Stem Cells in Research and as Biotherapeutics
    • Biopharmaceutical Production Considerations
      • Posttranslational Modifications
      • Upstream Processing vs Downstream Processing
      • Cell Culture Practices and Regulatory Guidelines
      • Validation of Facilities
      • Maintaining Sterilization Standards
  • Cell Culture Technologies
    • Introduction and Overview
    • Milestones in Cell Culture Development
    • Cells for Biopharmaceutical Production
      • Bacteria and Yeast Systems
      • Animal Cell Systems
      • Insect Cell Systems
    • Advantages/Disadvantages of Cell Culture Systems
      • Table Approximate Times from Introduced Gene to Protein Production at Useable Levels
      • Table Advantages and Disadvantages of Selected Cell Culture Systems
    • Genetically Modified Cells for Biopharmaceutical Development
      • A Brief History of Biotechnology
      • Science of Genetic Manipulation
    • Dominant Cell Lines Utilized in Biopharmaceutical Production
      • Chinese Hamster Ovary (CHO)
      • SP2/0 and NS0
      • HEK293 and PER.C6
    • Cell Lines and Cell Banks
    • Fermentors and Bioreactors
      • Stirred-tank Reactors
      • Airlift Fermentors
      • Packed Bed Reactors
      • Hollow-fiber Reactors
      • Single-use/Disposable Systems
      • Perfusion Bioreactors
    • Fermentation Processes
      • Batch and Fed-Batch Fermentation
      • Suspended versus Adherent Cells
      • Microencapsulation
    • Advances in Cell Culture Technologies: 3D Cell Culture
      • Table Selected Currently Applied 3D Cell Culture Methods
  • Cell Culture Consumables
    • Cell Culture Environment
    • Functions and Components of Basal Media
      • pH and Osmotic Pressure
      • Energy Sources
      • Nutrients
    • Cell Culture Media
      • Lysogeny Broth (LB)
      • Classical Media
      • Serum-Free Media
      • Protein-Free Media
      • Chemically Defined Media
      • Specialty Media
    • Sera
    • Sources of Sera
    • Bovine Serum Safety Issues and Regulations
    • Shift to Serum-Free Media
      • Table Selected Alternatives to Animal Sera Products for Hybridoma, Myeloma, and CHO Cell Lines
    • Reagents
    • Major Types of Biological Reagents
      • Amino Acids
      • Growth Factors and Cytokines
      • Albumin
      • Transferrin
      • Thrombin
      • Growth Supplements
      • Protease Inhibitors
      • Attachment Factors
    • Shifting Toward Non-Animal Derived Reagents
    • Addressing Reagent Safety Issues
  • Cell Culture Market
    • Overview
    • Market Drivers
      • Current and Future Trends
      • Cell Culture-Based Vaccine Production
      • Impact of Biosimilars on the Cell Culture Market
      • Stem Cell Research Also Drives the Cell Culture Market
    • Cell Culture Market Forecast
      • Table Global Cell Culture Market, 2012-2022 (mil US$)
    • Global Cell Culture Market Share by Region
      • Global Cell Culture Market Share by Region, 2017 and 2022
        • Table Global Cell Culture Market by Region/Country, 2017 (%)
        • Table Global Cell Culture Market by Region/Country, 2022 (%)
        • Table Global Cell Culture Market by Region/Country, 2017 and 2022 (mil US$)
      • Asia Pacific Region Will Continue to Gain Market Share
      • China Expected to Become a Leading Biopharmaceuticals Market, Supporting Demand for Cell Culture
    • Cell Culture Product Market by Type
      • Table Global Cell Culture Market by Segment, 2012 – 2022 (mil US$)
    • Media
      • Table Global Cell Culture Media Market, 2012 – 2022 (mil US$)
      • Market Share by Media Type
        • Table Global Cell Culture Media Market by Type, 2017 (%)
        • Table Global Cell Culture Media Market by Type, 2022 (%)
      • Comparison of Serum versus Serum-Free Media
        • Table Advantages and Disadvantages of Using Serum in Cell Culture Media
      • Liquid versus Powdered Media
    • Sera
      • Table Global Cell Culture Sera Market, 2012 – 2022 (mil US$)
      • Table Global Cell Culture Sera by Type, 2017 (%)
      • Table Global Cell Culture Sera by Type, 2022 (%)
    • Reagents
      • Table Global Cell Culture Reagent Market, 2012 – 2022 (mil US$)
    • Reagent Types
      • Cytokines and Growth Factors
      • Cell Dissociation Reagents
      • Buffers and Salt Solutions
      • Other Reagents
        • Table Global Cell Culture Reagent Market by Type, 2017 (%)
        • Table Global Cell Culture Reagent Market by Type, 2022 (%)
    • Cell Culture Supplier Market Share
    • Market Leaders in Cell Culture, 2017
      • Table Cell Culture Market Share by Company, 2017
    • Acquisitions & Divestitures
      • Table Selected Acquisitions & Divestitures
    • Cooperative Agreements
      • Table Selected Cooperative Agreements
  • Company Profiles
    • Analytical Biological Services Incorporated
      • Table Analytical Biological Services Corporate Summary
      • Company Overview
      • Cell Culture Products
      • Company Financials
    • Athena Enzyme Systems
      • Table Athena Enzyme Systems Corporate Summary
      • Company Overview
      • Cell Culture Products
      • Company Financials
    • Avantor Incorporated
      • Table Avantor Corporate Summary
      • Company Overview
      • Cell Culture Products
      • Company Financials
    • BD Biosciences
      • Table BD Biosciences Corporate Summary
      • Company Overview
      • Cell Culture Products
      • Company Financials
        • Table BD Biosciences Unit Revenue (FY2014-2017; mil US$)
    • Bio-Techne Corporation
      • Table Bio-Techne Corporate Summary
      • Company Overview
      • Cell Culture Products
      • Company Financials
        • Table Bio-Techne Sales (FY 2015-2018; mil US$)
    • BioreclamationIVT LLC
      • Table BioreclamationIVT Corporate Summary
      • Company Overview
      • Cell Culture Products
      • Company Financials
    • Cell Essentials Incorporated
      • Table Cell Essentials Corporate Summary
      • Company Overview
      • Cell Culture Products
      • Company Financials
    • CellGenix GmbH
      • Table CellGenix Corporate Summary
      • Company Overview
      • Cell Culture Products
      • Company Financials
    • Corning Life Sciences
      • Table Corning Life Sciences Corporate Summary
      • Company Overview
      • Cell Culture Products
      • Company Financials
        • Table Corning Life Sciences Revenues from Cell Culture Products: (2015-2017; mil US$)
    • GE Healthcare Life Sciences
      • Table GE Healthcare Life Sciences Corporate Summary
      • Company Overview
      • Cell Culture Products
      • Company Financials
        • Table General Electric Revenues from Cell Culture Products: (2016-2017; bil US$)
    • Gemini Bio-Products
      • Table Gemini Bio-Products Corporate Summary
      • Company Overview
      • Cell Culture Products
      • Company Financials
    • InVitria
      • Table InVitria Corporate Summary
      • Company Overview
      • Cell Culture Products
      • Company Financials
    • Irvine Scientific Sales Company Incorporated
      • Table Irvine Scientific Sales Summary
      • Company Overview
      • Cell Culture Products & Services
      • Company Financials
    • Kohjin Bio Company Limited
      • Table Kohjin Bio Company Limited Corporate Summary
      • Company Overview
      • Cell Culture Products
      • Company Financials
    • Lonza Group Limited
      • Table Lonza Group Limited Summary
      • Company Overview
      • Cell Culture Products
      • Cooperative Agreements
      • Acquisitions
      • Company Financials
        • Table Lonza Group Revenues from Cell Culture Products: (2015-2017; mil US$)
    • MilliporeSigma
      • Table MilliporeSigma Corporate Summary
      • Company Overview
      • Cell Culture Products
      • Company Financials
        • Table Merck Revenue (2014-2017; mil US$)
    • MP Biomedicals LLC
      • Table MP Biomedicals Corporate Summary
      • Company Overview
      • Cell Culture Products
      • Company Financials
    • Nissui Pharmaceutical Company Limited
      • Table Nissui Pharmaceutical Corporate Summary
      • Company Overview
      • Cell Culture Products
      • Company Financials
        • Table Nissui Pharmaceutical Revenue (FY 2015-FY 2018; mil US$)
    • PromoCell GmbH
      • Table PromoCell Corporate Summary
      • Company Overview
      • Cell Culture Products
      • Company Financials
    • Quality Biological Incorporated
      • Table Quality Biological Corporate Summary
      • Company Overview
      • Cell Culture Products
      • Company Financials
    • SBH Sciences Incorporated
      • Table SBH Sciences Corporate Summary
      • Company Overview
      • Cell Culture Products
      • Company Financials
    • ScienCell Research Laboratories Incorporated
      • Table ScienCell Research Laboratories Corporate Summary
      • Company Overview
      • Cell Culture Products
      • Company Financials
    • Selexis SA
      • Table Selexis Corporate Summary
      • Company Overview
      • Cell Culture Technology
      • Cooperative Agreements
      • Company Financials
    • Serana Europe GmbH
      • Table Serana Europe Corporate Summary
      • Company Overview
      • Cell Culture Products
      • Company Financials
    • STEMCELL Technologies Incorporated
      • Table STEMCELL Technologies Corporate Summary
      • Company Overview
      • Cell Culture Products
      • Basal Media
      • Semi-Solid Media
      • Specialized Media
      • Tissue & Cell Culture Dissociation Reagents
      • Cooperative Agreements
      • Company Financials
    • Takara Bio Incorporated
      • Table Takara Bio Incorporated Corporate Summary
      • Company Overview
      • Cell Culture Products
      • Company Financials
        • Table Takara Bio's Bioindustry Segment Sales: (FY2015-FY2018; mil US$)
    • Thermo Fisher Scientific Incorporated
      • Table Thermo Fisher Scientific Corporate Summary
      • Company Overview
      • Acquisitions
      • Cell Culture Products
      • Media
      • Reagents
      • Fetal Bovine Sera
      • Specialty Cell Culture Products
      • Other Cell Culture Products
      • Company Financials
        • Table Thermo Fisher Scientific Revenue (2014-2017; mil US$)
    • Wisent Incorporated
      • Table Wisent Corporate Summary
      • Company Overview
      • Cell Culture Products
      • Company Financials
  • Appendix: Company Directory

Download our eBook: How to Succeed Using Market Research

Learn how to effectively navigate the market research process to help guide your organization on the journey to success.

Download eBook

Share this report