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Cell Culture: The World Market for Media, Sera and Reagents, 2nd Edition


Attention: There is an updated edition available for this report.

Cell culture is a major foundation of biopharmaceutical development, bioprocessing and manufacturing. As the biopharmaceutical market grows, so should interest in the cell culture products market. Biopharmaceutical products are developed from large, complex protein molecules, which require equally complex manufacturing methods and an array of analytical techniques. As growing cells for biopharmaceutical production is slow, expensive and complicated, optimizing cell culture development is of paramount concern to companies developing biopharmaceuticals.

This report, Cell Culture represents the second time that Kalorama has focused on culture used in the research and production of biopharmaceuticals, analyzing the world cell culture market and the major trends driving this market in three specific segments:

  • Media,
  • Sera, and
  • Reagents

In addition to a thorough discussion of the technologies and techniques currently employed and emerging in the cell culture area, the Kalorama's exhaustive report provides specific information on:

  • Market Size, growth, and forecasts of the segments through 2013
  • Competitive Market Share by leading supplier as of 2008.
  • Estimated Market Share by Region (North America, Europe, U.S.)
  • Key Market Drivers and Restraints for suppliers, including discussions of biopharmaceutical pipelines, biomedical R&D directions, and the future of transgenic plant and animal production.
  • Review of the various expression systems (Bacteria, Yeast, Insect, and Mammal) and the biopharmaceutical product manufactured by these systems
  • Discussion of the preferences in media types vying for dominance in the market, including the following:
    • ADCF - animal derived component free media
    • CD - chemically defined media
    • CSFM - complete serum free medium
    • PF - protein free media
    • SF - serum free media
    • SFM - serum free medium
  • Major Trends Impacting the Market stem cell research (including plans of major companies)cell culture-based vaccine Production and generic bipharmaceuticals
  • Profiles of 27 Leading Suppliers and information about M&A activities in recent years

The information for this report was gathered using both primary and secondary research including comprehensive research of secondary sources such as company literature, databases, investment reports, and medical and business journals. Telephone interviews and email correspondence were the primary method of gathering information. For the purpose of this study Kalorama Information conducted interviews with key industry officials, consultants, and government personnel. These sources were the primary basis in gathering information specifically relating to revenue and market share data presented in this report. Specific interviews with pharmaceutical company and cell culture supply company representatives included marketing directors, division managers, and product representatives.

All Kalorama reports advertise the single user price, which limits access to one user. We also feature department and global pricing for reports that will be utilized by more than one user at your company. Please ask your sales representative or select the correct license on our website.

For Kalorama's take on the healthcare news of the week, based on our analysis of healthcare markets, follow Kalorama Information's Key Point Blog at http://kaloramakeypoint.blogspot.com/


  • Executive Summary
    • SCOPE AND METHODOLOGY
    • CELLS FOR BIOPHARMACEUTICAL PRODUCTION
      • Bacteria and Yeasts Systems
      • Animal Cell Systems
      • Insect Cell Systems
      • Cell Lines and Cell Banks
    • FERMENTORS AND BIOREACTORS
      • Stirred-tank Reactors
      • Airlift Fermentors
      • Packed Bed Reactors
      • Hollow-fiber Reactor
      • Disposable Systems
    • FERMENTATION PROCESSES
      • Batch and Fed-Batch Fermentation
      • Suspended vs. Anchored Cells
      • Microencapsulation
    • CELL CULTURE ENVIRONMENT
      • Functions and Components of Basal Media
    • CELL CULTURE MEDIA
      • Lysogeny broth (LB)
      • Classical Media
      • Serum-free Media
      • Protein-free Media
      • Chemically Defined Media
      • Specialty Media
    • SERA
    • REAGENTS
      • Shifting Towards Non-animal Derived Reagents
      • Addressing Reagent Safety Issues
    • WORLD CELL CULTURE MARKET
      • Impact of Shift to Serum-free Products on Cell Culture Suppliers
      • Impact of Shift to Serum-free Products on Research
      • Impact of Shift Serum-free Products on Biopharmaceutical Manufacturers
      • Cell Culture Market and Forecast
        • Table Worldwide Cell Culture Market, 2003-2013
    • TRENDS IMPACTING THE CELL CULTURE MARKET
  • Genetically Modified Cells forBiopharmaceutical Development
    • GROWING DEMAND FOR BIOPHARMACEUTICALS
      • Table Biopharmaceuticals Approved in the USA and/or the EU in 2007
      • Demand Increasing for Cell Culture Products
    • A BRIEF HISTORY OF BIOTECHNOLOGY
      • Science of Genetic Manipulation
    • FROM PETRI DISH TO BIOPHARMACEUTICAL
      • Upstream Bioprocessing: Cell Culture Expression Systems
      • Cells for Biopharmaceutical Production
      • Advantages/Disadvantages of Cell Culture Systems
        • Table Approximate times from Introduced Gene to Protein Production at Useable Levels (Expression System, Approximate Time)
        • Table Disadvantages/Advantages of Cell Culture Systems
      • Cell Lines and Cell Banks
      • Biopharmaceuticals Produced from Cell Culture
        • Table Selected Biopharmaceuticals Produced from Bacteria, Yeast and Mammalian Cells (Product, Manufacturer, Indication)
    • CELL CULTURE PRACTICES AND REGULATORY GUIDELINES
      • Validation of Facilities
      • Maintaining Sterilization Standards
  • Cell Culture Technology
    • INTRODUCTION AND OVERVIEW
      • Milestones in Cell Culture Development
    • CELL LINES FOR BIOPRODUCTION
      • Predominant Cell Lines
      • Sources: Largest Collections of Cell Lines
    • FERMENTORS AND BIOREACTORS
    • TYPES OF BIOREACTORS/FERMENTORS
    • FERMENTATION PROCESSES
      • Batch and Fed-Batch Fermentation
      • Suspended vs. Anchored Cells
      • Microencapsulation
    • CELL CULTURE ENVIRONMENT
      • Functions and Components of Basal Media
    • CELL CULTURE MEDIA
      • Types of Media
    • SERA
      • Sources of Sera
      • Bovine Serum Safety Issues and Regulations
      • Shift to Serum-free Media
        • Table Selected Products/Companies Offering Alternatives to Animal Sera Products for Hybridoma, Myeloma and CHO cell lines
    • REAGENTS
      • Major Types of Biologic Reagents
      • Shifting Towards Non-animal Derived Reagents
      • Addressing Reagent Safety Issues
  • Cell Culture Market: Current and Future Trends
    • OVERVIEW
    • SHIFT AWAY FROM SERUM-BASED CELL CULTURE
      • Impact of Shift to Serum-free Products on Cell Culture Suppliers
        • Table Selected Brand Name Serum-Free Formulations of Cell Culture Products Currently on the Market
      • Impact of Shift to Serum-free Products on Research
      • Life Technologies' End Run Around the BSE Issue
    • CELL CULTURE MARKET
      • Market Drivers
      • Cell Culture Market and Forecast
        • Table Worldwide Cell Culture Market ($ billion)
      • Segment Analysis
        • Table World Cell Culture Market by Segment: Media, Sera and Reagents ($million)
      • Market Characteristics
      • Market Share: Cell Culture Suppliers
        • Table Cell Culture Company Revenues and Market Share, 2008 (Top Five Companies, Others)
    • TRENDS IMPACTING THE CELL CULTURE MARKET
      • Stem Cell Research
      • Cell Culture-based Vaccine Production
      • Generic Biopharmaceuticals
      • Transgenically Produced Biopharmaceuticals
  • Company Profiles
    • ADVANCED BIOTECHNOLOGIES, INC.
      • History and Lines of Business
      • Cell Culture Products and Services
    • AMRESCO, INC.
      • History and Lines of Business
      • Cell Culture Products
    • ANALYTICAL BIOLOGICAL SERVICES INC.
      • History and Lines of Business
      • Cell Culture Products
    • ATLANTA BIOLOGICALS, INC.
      • History and Lines of Business
      • Cell Culture Products
    • ATHENA ENZYME SERVICES
      • History and Lines of Business
      • Cell Culture Products
    • BD BIOSCIENCES
      • History and Lines of Business
      • Cell Culture Products
      • Financial Information
    • BIOCHROM AG
      • History and Lines of Business
      • Cell Culture Products
    • CELL ESSENTIALS, INC.
      • History and Lines of Business
      • Cell Culture Products
    • CELLGENIX TECHNOLOGIE TRANSFER GMBH
      • History and Lines of Business
      • Cell Culture Products and Services
    • IRVINE SCIENTIFIC
      • History and Lines of Business
      • Cell Culture Products
    • J R SCIENTIFIC, INC.
      • History and Development
      • Cell Culture Products
    • LIFE TECHNOLOGIES CORPORATION
      • History and Lines of Business
      • Cell Culture Products
      • Financial Information
    • LONZA BIOSCIENCE
      • History and Lines of Business
      • Cell Culture Products and Services
      • Financial Information
    • MEDIATECH, INC.
      • History and Lines of Business
      • Cell Culture Products
    • MILLIPORE CORPORATION
      • History and Lines of Business
      • Cell Culture Products
      • Financial Information
    • MP BIOMEDICALS
      • History and Lines of Business
      • Cell Culture Products
    • PAA LABORATORIES, INC.
      • History and Lines of Business
      • Cell Culture Products
    • PROMOCELL GMBH
      • History and Lines of Business
      • Cell Culture Products
    • QUALITY BIOLOGICAL, INC.
      • History and Lines of Business
      • Cell Culture Products
    • R&D SYSTEMS, INC.
      • History and Lines of Business
      • Cell Culture Products
    • SBH SCIENCES
      • History and Lines of Business
      • Cell Culture Products
    • SELEXIS SA
      • History and Lines of Business
      • Cell Culture Products
    • SERACARE LIFE SCIENCES, INC.
      • History and Lines of Business
      • Cell Culture Products
      • Financial Information
    • SIGMA-ALDRICH CORPORATION
      • History and Lines of Business
      • Cell Culture Products
      • Financial Information
    • THERMO FISHER SCIENTIFIC, INC.
      • History and Lines of Business
      • Cell Culture Products
      • Financial Information
    • USB CORPORATION
      • History and Lines of Business
      • Cell Culture Products
    • WISENT, INC.
      • History and Lines of Business
      • Cell Culture Products
  • Company Directory
  • Professional Organizations

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