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The World Market for Anti-Infectives, Volume III: Antivirals

This volume of Kalorama Information’s World Market for Anti-Infectives series focuses on three general product segments of antiviral treatment:

  • Nucleoside Analogs
  • Protease Inhibitors
  • Other Misc. Antivirals

The report covers both currently marketed and late stage development antiviral products in detail. For each segment, the report provides an

  • An overview
  • Description of products on the market
  • Description of products in development
  • Market estimates and forecasts through 2009
  • Market segmentation by infection type
  • Market segmentation by geographic region
  • Market share of leading suppliers
  • Market share of leading products

The report also includes statistical (epidemiologic and demographic) information for viral infections by type worldwide, with special emphasis on the United States and describes the major clinical, business, and regulatory trends shaping the global and domestic markets.

The information for this report was gathered using both primary and secondary research including comprehensive research of secondary sources such as company literature, databases, investment reports, and medical and business journals. Telephone interviews and email correspondence were the primary method of gathering information. For the purpose of this study Kalorama Information conducted interviews with key industry officials, consultants, health care providers, and government personnel. These sources were the primary basis in gathering information specifically relating to revenue and market share data presented in this report. Specific interviews with pharmaceutical company representatives included marketing directors, division managers, and product representatives.

All market data pertains to the world market at the manufacturers’ level. The base year for data was 2004. Historical data are provided for the years 2002 and 2003, with forecast data provided for 2005 through 2009. Compound annual growth rates (CAGRs) are provided for the 2002-2004, 2004-2009 and 2002-2009 periods for each industry segment covered. Competitive analysis is provided for the year 2004. The forecasted market analysis for 2005-2009 was based on probability of approval and sales of products in late stage development, product marketing, and demographic trends.


  • Executive Summary
    • INTRODUCTION
    • SCOPE AND METHODOLOGY
    • SIZE AND GROWTH OF THE MARKET
      • Table The World Market for Antiviral Drugs 2002-2009
      • Table SIZE AND GROWTH OF THE MARKET
    • ISSUES AND TRENDS AFFECTING MARKET
    • LEADING COMPETITORS
  • Introduction
    • INTRODUCTION TO VIRUSES
      • Examples of Pathogenic Viruses
    • VIRUS FUNCTION AND LIFE HISTORY
      • Replication in DNA Viruses
      • Replication of RNA Viruses
      • Replication in Retroviruses
        • Table Host Cell Receptors
    • HOST DEFENSES AGAINST VIRUSES
    • VIRAL PLOYS TO INVADE HOST CELLS AND CIRCUMVENT HOST RESPONSES
      • Invasion of Host Cells
      • Subversion of the Immune Response
      • Avoidance of Immune Detection and Attack by Killer Cells
    • HIV AND AIDS
    • DEMOGRAPHICS AND EPIDEMIOLOGY
      • Cytomegalovirus
      • Hepatitis B Virus
      • Hepatitis C Virus (HCV)
      • Herpes
      • Human Immunodeficiency Virus (HIV)
      • Human Papillomavirus (HPV)
      • Influenza
      • Respiratory Syncytial Virus (RSV)
        • Table Estimated World and U.S. Incidence of Viral Infections
      • Population Demographics
        • Table World Population by Selected Geographical Region, 2004–2050
        • Table Estimated World Population by Age and Geographical Region, 2004
  • Nucleoside Analogs, Transcriptase Inhibitors, and DNA Polymerase Inhibitors
    • OVERVIEW
    • DESCRIPTION OF PRODUCTS
      • Nucleoside Reverse Transcriptase Inhibitors
      • Nucleotide Analogue Reverse Transcriptase Inhibitors
      • Combination Nucleoside Reverse Transcriptase Inhibitors
        • Table Currently Available Nucleoside Reverse Transcriptase Inhibitors
      • Non-Nucleoside Reverse Transcriptase Inhibitors
        • Table Currently Available Non-Nucleoside Reverse Transcriptase Inhibitors
      • DNA Polymerase Inhibitors
        • Table Currently Available DNA Polymerase Inhibitors
    • RESEARCH AND DEVELOPMENT
      • Table Nucleoside Analogs, Transcriptase Inhibitors, and DNA Polymerase Inhibitors in Development (Product, Developer, Phase)
    • MARKET SIZE AND GROWTH
      • Table The Market for Nucleoside Analogs, Transcriptase Inhibitors and DNA Polymerase Inhibitors 2002-2009
      • Table MARKET SIZE AND GROWTH
      • Table Nucleoside Analog, Transcriptase Inhibitors and DNA Polymerase Inhibitor Market Estimated Products Sales by Infection Type, 2004
      • Table Nucleoside Analog, Transcriptase Inhibitors and DNA Polymerase Inhibitor Market Estimated Products Sales by Geographic Region, 2004
    • COMPETITIVE ANALYSIS
      • Table Nucleoside Analog, Transcriptase Inhibitors and DNA Polymerase Inhibitor Market Estimated Revenues and Market Share of Leading Suppliers 2004
      • Table Estimated Sales and Market Share of Top Nucleoside Analogs, Transcriptase Inhibitors and DNA Polymerase Inhibitors 2004
  • Protease Inhibitors
    • OVERVIEW
    • DESCRIPTION OF PRODUCTS
      • Single Agents
      • Combination Protease Inhibitors
        • Table Currently Available Protease Inhibitors (Type, Brand, and Manufacturer)
    • RESEARCH AND DEVELOPMENT
      • Table Protease Inhibitors in Development (Product, Developer, Phase, Earliest Approval Date)
    • MARKET SIZE AND GROWTH
      • Table The Market for Protease Inhibitors 2002-2009
      • Table Compound Annual Growth Rate
      • Table Protease Inhibitor Market Estimated Products Sales by Geographic Region, 2004
    • COMPETITIVE ANALYSIS
      • Table Protease Inhibitor Market Estimated Revenues and Market Share of Leading Suppliers 2004
      • Table Protease Inhibitor Market Estimated Sales of Top Protease Inhibitors 2004
  • Other Antivirals
    • OVERVIEW
    • DESCRIPTION OF PRODUCTS
      • Table Currently Available Other Antivirals (Type, Brand, and Manufacturer)
    • RESEARCH AND DEVELOPMENT
      • Table Other Antivirals in Development (Product, Developer, Phase, Earliest Approval Date)
    • MARKET SIZE AND GROWTH
      • Table The Market for Other Antivirals 2002-2009
      • Table MARKET SIZE AND GROWTH
      • Table The Market for Other Antivirals Estimated Products Sales by Infection Type, 2004
      • Table The Market for Other Antivirals Estimated Products Sales by Geographic Region, 2004
    • COMPETITIVE ANALYSIS
      • Table The Market for Other Antivirals Estimated Revenues and Market Share of Leading Suppliers 2004
      • Table Other Antiviral Market Estimated Sales of Other Antiviral Products 2004
  • Issues and Trends
    • INTRODUCTION
    • ANTIVIRAL DRUG RESISTANCE
    • HIV DRUG COST CONTROVERSY
    • ANTIRETROVIRAL TREATMENT REGIMENS
    • HIV AND WOMEN
      • Table Women (15 to 49) Living with HIV/AIDS by Region 2004
    • GLOBAL SURVEILLANCE
    • BIOCHEMICAL PREVENTION AND TREATMENT OF VIRAL INFECTIONS
    • NEW TREATMENT FOR HEPATITIS C
    • COSTS AND FUNDING OF HIV TREATMENT
      • Table Funding for HIV/AIDS
    • ACCESS TO HIV/AIDS TREATMENT
      • Table Access Needs of Adults and Children with HIV by Region 2004
      • Table Antiretroviral Access for HIV Infected Individuals by Region in the Developing World
  • Total Market Size and Forecast
    • OVERVIEW
    • TOTAL MARKET SIZE AND FORECAST
      • Table The World Market for Antiviral Drugs 2002-2009
      • Table TOTAL MARKET SIZE AND FORECAST
      • Table World Market for Antiviral Drugs by Type 2002-2009
      • Table TOTAL MARKET SIZE AND FORECAST
  • Corporate Profiles
    • INTRODUCTION
    • ABBOTT LABORATORIES
    • BOEHRINGER INGELHEIM GMBH
    • BRISTOL-MYERS SQUIBB COMPANY
    • GILEAD SCIENCES, INC.
    • GLAXOSMITHKLINE
    • MEDIMMUNE, INC.
    • MERCK & COMPANY, INC.
    • NOVARTIS PHARMACEUTICALS CORPORATION
    • ROCHE
    • SCHERING-PLOUGH CORPORATION
  • Company Names and Addresses

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