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Global Opioid-Induced Constipation Market 2015-2019

  • Executive Summary
  • List of Abbreviations
  • Scope of the Report
    • Market Overview
    • Product Offerings
  • Product Profiles
    • Amitiza
      • Movantik/Moventig
      • Relistor
  • Market Research Methodology
    • Market Research Process
    • Research Methodology
      • Table Market Research Methodology
  • Introduction
  • Disease Overview
    • Understanding Opioid-induced Constipation
    • Symptoms
    • Pathophysiology
    • Epidemiology
    • Diagnosis
      • Patient History
      • Bristol Stool Form Scale
      • Physical Examination
      • Laboratory Tests
      • Further Investigational Procedures
    • Treatment and Management
      • Pharmacotherapeutic Approach
      • Non-pharmacotherapeutic Approach
  • Pipeline Portfolio
    • Table Pipeline Drugs: Opioid-induced Constipation
    • Key Information of Pipeline Molecules
      • Naldemedine
      • Linaclotide
      • Axelopran/TD-1211
      • SP-333
      • Oral Naloxone
  • Market Landscape
    • Market Overview
      • Table Snapshot of Global Opioid-induced Constipation Market
    • Market Size and Forecast
      • Table Global Opioid-induced Constipation Market 2014-2019 ($ millions)
    • Five Forces Analysis
  • Market Segmentation by Mechanism of Action
    • Table Segmentation of Global Opioid-induced Constipation Market by Mechanism of Action
    • Peripherally Acting Mu-opioid Receptor Antagonist
    • Locally Acting Chloride Channel Activator
    • Others
  • Market Segmentation by Route of Administration
    • Table Segmentation of Global Opioid-induced Constipation Market by Route of Administration
    • Oral
    • Parenteral
  • Market Segmentation by Dosage Form
    • Table Segmentation of Global Opioid-induced Constipation Market by Dosage Form
    • Solid
    • Liquid
  • Geographical Segmentation
    • Table Segmentation of Global Opioid-induced Constipation Market by Geography 2014
  • Buying Criteria
  • Market Growth Drivers
    • Table Drivers of Global Opioid-induced Constipation Market
  • Drivers and their Impact
  • Market Challenges
    • Table Challenges in the Global Opioid-induced Constipation Market
  • Impact of Drivers and Challenges
  • Market Trends
    • Table Trends of Global Opioid-induced Constipation Market
  • Trends and their Impact
  • Vendor Landscape
    • Competitive Scenario
      • Key News
      • Mergers and Acquisitions
    • Market Share Analysis 2014
      • Takeda Pharmaceutical
        • Table Takeda Pharmaceuticals: Key Takeaways
      • Valeant Pharmaceuticals International
        • Table Valeant Pharmaceuticals International: Key Takeaways
      • AstraZeneca
        • Table AstraZeneca: Key Takeaways
    • Other and Future Prominent Vendors
  • Key Vendor Analysis
    • AstraZeneca plc
      • Key Facts
      • Business Overview
      • Business Segmentation by Revenue 2013
        • Table AstraZeneca plc: Business Segmentation by Revenue 2013
      • Business Segmentation by Revenue 2011-2013
        • Table AstraZeneca plc: Business Segmentation by Revenue 2011-2013 (US$ million)
      • Sales by Geography
        • Table AstraZeneca plc: Sales by Geography 2013
      • Business Strategy
      • Key Developments
      • SWOT Analysis
    • Takeda Pharmaceuticals
      • Key Facts
      • Business Overview
      • Business Segmentation by Revenue 2013
        • Table Takeda Pharmaceuticals: Business Segmentation by Revenue 2013
      • Business Segmentation by Revenue 2013
        • Table Takeda Pharmaceuticals: Business Segmentation by Revenue 2013 (US$ million)
      • Geographical Segmentation by Revenue 2013
        • Table Takeda Pharmaceuticals: Geographical Segmentation by Revenue 2013
      • Business Strategy
      • Recent Developments
      • SWOT Analysis
    • Valeant Pharmaceuticals International
      • Key Facts
      • Business Overview
      • Business Segmentation by Revenue 2013
        • Table Valeant Pharmaceuticals International: Business Segmentation by Revenue 2013
      • Business Segmentation by Revenue 2012 and 2013
        • Table Valeant Pharmaceuticals International: Business Segmentation by Revenue 2012 and 2013 (US$ million)
      • Sales by Geography
        • Table Valeant Pharmaceuticals International: Sales by Geography 2013
      • Business Strategy
      • Key Developments
      • SWOT Analysis
  • Other Reports in this Series

Global Opioid-Induced Constipation Market 2015-2019

About Opioid-induced Constipation

Opioids are administered to the patients with acute and non-cancer chronic pain. They have several adverse gastrointestinal effects, one of which is opioid-induced constipation. The opioid analgesics produce analgesia by the activation of the mu receptors found in the CNS and PNS. These drugs affect the motility, tone, and contractility of the bowel functions, which results in the delay in the transit of fecal contents. The opioids also cause a reduction in the secretion of digestive enzymes and also cause partial gastroparesis. Some of the common symptoms of opioid-induced constipation are hard and dry stools, painful defecation, bloating, distention and bulged abdomen, feeling lethargic, and loss of appetite. Opioid-induced constipation can be managed by changing lifestyle along with the use of targeted therapies and other OTC and off-label drugs.

Technavio's analysts forecast the global opioid-induced constipation market to grow at a CAGR of 30.18% over the period 2014-2019.

Covered in this Report

This report covers the present scenario and the growth prospects of the global opioid-induced constipation market for 2015-2019. To calculate the market size, the report considers revenue generated from sales of various drugs used in the treatment of opioid-induced constipation, which includes branded drugs, off-label products, and OTC drugs. On the basis of the mechanism of action of drugs, the market is grouped into the following categories:

  • Peripherally Acting Mu-opioid Receptor Antagonist
  • Locally Acting Chloride Channel Activator
  • Others
  • On the basis of the route of administration of drugs, the market is grouped into the following categories:
    • Oral
    • Parenteral
    • On the basis of the dosage form of drugs, the market is grouped into the following categories:
      • Solid
      • Liquid
      Technavio's report, Global Opioid-induced Constipation Market 2015-2019, has been prepared based on an in-depth market analysis with inputs from industry experts. The report covers the market landscape and its growth prospects in the coming years. The report also includes a discussion of the key vendors operating in this market.
    Key Regions
    • Americas
    • APAC
    • EMEA
    Key Vendors
    • AstraZeneca
    • Takeda Pharmaceutical
    • Valeant Pharmaceuticals International
    Other Prominent Vendors
    • Abbott
    • Bayer
    • Boehringer Ingelheim
    • C.B. Fleet
    • Cosmo Pharmaceuticals
    • Daewoong
    • Daiichi Sankyo
    • GlaxoSmithKline
    • Ironwood Pharmaceuticals
    • Johnson & Johnson
    • Merck
    • Mundipharma
    • Nektar Therapeutics
    • Pfizer
    • Progenics Pharmaceuticals
    • Shionogi
    • SLA Pharma
    • Sucampo
    • Synergy Pharmaceuticals
    • Theravance
    Market Driver
    • Unmet Medical Needs
    • For a full, detailed list, view our report
    Market Challenge
    • Availability of OTC and Off-label Drugs
    • For a full, detailed list, view our report
    Market Trend
    • Shift to Targeted Therapy
    • For a full, detailed list, view our report
    Key Questions Answered in this Report
    • What will the market size be in 2019 and what will the growth rate be?
    • What are the key market trends?
    • What is driving this market?
    • What are the challenges to market growth?
    • Who are the key vendors in this market space?
    • What are the market opportunities and threats faced by the key vendors?
    • What are the strengths and weaknesses of the key vendors?


    Press Release

    Technavio Announces the Publication of its Research Report – Global Opioid-Induced Constipation Market 2015-2019

    Technavio recognizes the following companies as the key players in the Global Opioid-Induced Constipation Market: AstraZeneca, Takeda Pharmaceutical and Valeant Pharmaceuticals International

    Other Prominent Vendors in the market are: Abbott, Bayer, Boehringer Ingelheim, C.B. Fleet, Cosmo Pharmaceuticals, Daewoong, Daiichi Sankyo, GlaxoSmithKline, Ironwood Pharmaceuticals, Johnson & Johnson, Merck, Mundipharma, Nektar Therapeutics, Pfizer, Progenics Pharmaceuticals, Shionogi, SLA Pharma, Sucampo, Synergy Pharmaceuticals and Theravance

    Commenting on the report, an analyst from Technavio’s team said: “The market was served by various off-label and OTC therapies to treat the condition. However, in 2008, Relistor, a targeted therapy for treating opioid-induced constipation, was approved by the US FDA and the EMA. This drug is a peripherally acting mu-opioid receptor antagonist and was the first targeted therapy to obtain approval for this indication. Movantik/Moventig, also a peripherally acting mu-opioid receptor antagonist, was approved by the US FDA and the EMA in 2014 and is a targeted therapy for this indication. These drugs reduce the undesirable effects of the opioid analgesics without affecting its analgesic effects. Therefore, these drugs are increasingly becoming the preferred medication to treat opioid-induced constipation.”

    According to the report, the low levels of awareness about opioid-induced constipation among patients and the medical fraternity have resulted in the usage of off-label and OTC medications as the treatment options. However, these drugs are only partially successful in treating this condition. The entry of peripherally acting mu-opioid receptor antagonists such as Movantik/Moventig has driven the market significantly. The drug targets the underlying cause of opioid-induced constipation without affecting the analgesic action of the opioid drugs. Therefore, this is increasingly becoming the preferred treatment option for opioid-induced constipation.

    Further, the report states that the availability of OTC and off-label drugs restricts the market growth.

    Companies Mentioned

    AstraZeneca, Takeda Pharmaceutical, Valeant Pharmaceuticals International, Abbott, Bayer, Boehringer Ingelheim, C.B. Fleet, Cosmo Pharmaceuticals, Daewoong, Daiichi Sankyo, GlaxoSmithKline, Ironwood Pharmaceuticals, Johnson & Johnson, Merck, Mundipharma, Nektar Therapeutics, Pfizer, Progenics Pharmaceuticals, Shionogi, SLA Pharma, Sucampo, Synergy Pharmaceuticals, Theravance

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