Global Chiral Chromatography Column Market 2017-2021
About Chiral Chromatography Column
Chromatography is a physical method used to separate compounds. The sample distributes itself into different extents in two different, immiscible phases. The two immiscible phases could be a solid and a liquid, a gas and a liquid, or two different liquids. One of the two phases is a stationary phase (a solid or a liquid supported on a solid), and the other is a mobile phase, which moves with respect to the stationary phase. The mobile phase may be a liquid (liquid chromatography) or a gas (gas chromatography). All chromatographic methods involve passing a mobile phase through a stationary phase.
Technavio’s analysts forecast the global chiral chromatography column market to grow at a CAGR of 5.48% during the period 2017-2021.
Covered in this report
The report covers the present scenario and the growth prospects of the global chiral chromatography column market for 2017-2021. To calculate the market size, the report considers the revenue generated from the sales of chiral chromatography column systems.
The market is divided into the following segments based on geography:
Technavio Announces the Publication of its Research Report – Global Chiral Chromatography Column Market 2017-2021
Technavio recognizes the following companies as the key players in the global chiral chromatography column market: Agilent Technologies, Thermo Fisher Scientific, Shimadzu, and Merck.
Other Prominent Vendors in the market are: BD, Daicel, GE Healthcare, PerkinElmer, Phenomenex, Regis Technologies, Repligen, Tosoh, VWR International, Waters, W.R Grace, and ZirChrom Separations.
Commenting on the report, an analyst from Technavio’s team said: “One trend in market is rising proteomics market and life science sector. The proteomics market has been showing significant growth over the last few years. It is expected to reach approximately$20 million by 2018 due to the increasing demand for proteomics for diagnosis, drug discovery, and other procedures. Chiral chromatography column has a major role in proteomics drug discovery. It separates enantiomers, which are further analyzed for its therapeutic effects. The life science industry is also growing due to fast-growing population, increase in chronic diseases, increase in life expectancy, and higher disposable income. These factors increase the healthcare expenditure. The subsequent rise in the need for drug approvals tests will increase the use of chiral chromatography column. Hence, the increase in proteomics and life science market will result in the growth of the global chiral chromatography column market.”
According to the report, one driver in market is chromatography tests for drug approvals. Separation of chiral compounds has increasing importance in the pharmaceutical industry. The chirality of molecules causes a biological system to exhibit different responses to each enantiomer in a drug. The body is selective in chiral compounds. It interacts with racemate drug differently and metabolizes each enantiomer into different end products. Thus, while one enantiomer may produce desired therapeutic effect, another may be inactive or harmful. The enantiomers in a racemate drug may have differences in biological activities such as pharmacology, toxicology, and metabolism. For instance, Thalidomide prescribed as a sedative for pregnant women contains chiral carbon, which is a racemic mixture of (+) (R)- thalidomide and (-) (S)- thalidomide. It has been found that the enantiomer (-) (S)- thalidomide present in thalidomide has an adverse effect on newly born babies causing missing or abnormal arms, legs, or feet.
Further, the report states that one challenge in market is strong alternative techniques. High-cost equipment with long product life needs frequent and periodic maintenance. Modern instruments are sensitive and vulnerable to changing environmental influences and aging of materials. Companies generate a sizeable part of their revenue from providing servicing and support. Companies can generate additional revenue and profit by offering maintenance service within the in-service phase of the product lifecycle. For example, in 2015, Waters Corporation generated over 30% of sales from its water division segment, which include chiral chromatography columns, that deal with service support, spare parts, and customer training. However, from the consumer perspective, this need for maintenance is a challenge, especially for price-sensitive end-users. Therefore, the emergence of any substitute with improved performance, lifespan, and low price can threaten the market for chiral chromatography columns. For instance, kinetic resolution works on the principal that two enantiomers in a sample mixture will interact with a chiral reagent or an enzyme at different rates. Also, many chiral drugs like chloroquine, thalidomide, and ketoprofen need to be separated to improve purity and reduce adverse effects on patients. However, if the emphasis on asymmetric synthesis increases in the future, it will eliminate the need for separation of compounds with the help of chiral chromatography column. This can challenge the global chiral chromatography column market in future.
Agilent Technologies, Thermo Fisher Scientific, Shimadzu, Merck, BD, Daicel, GE Healthcare, PerkinElmer, Phenomenex, Regis Technologies, Repligen, Tosoh, VWR International, Waters, W.R Grace, and ZirChrom Separations.
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