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Hemoglobinopathies Market Size & Forecast By Type (Alpha Thalassemia, Beta thalassemia, Sickle Cell Disease, Hb Variants Diseases), By Therapy (Blood Transfusion, Iron Chelation Therapy, Bone Marrow Transplant, Hydroxyurea), By Diagnosis (Blood Testing, G

Hemoglobinopathies Market Size & Forecast By Type (Alpha Thalassemia, Beta thalassemia, Sickle Cell Disease, Hb Variants Diseases), By Therapy (Blood Transfusion, Iron Chelation Therapy, Bone Marrow Transplant, Hydroxyurea), By Diagnosis (Blood Testing, Genetic Testing, Prenatal Genetic Testing, Pre-implantation Genetic Diagnosis, Hemoglobin Electrophoresis) And Trend Analysis From 2012 To 2022

Global hemoglobinopathies market is expected to reach over USD 8.82 billion by 2022 according to a new report by Grand View Research Inc. Rising prevalence of hemoglobin disorders such as sickle cell anemia, thalassemia, Hb C, and Hb E is estimated to be the high impact rendering drivers of the market. According to the WHO, hemoglobin disorders are endemic in over 60% of 229 countries affecting over 70% of births. It is also reported that minimum 5% of the world population are carriers of significant variation.

Prevalence of hemoglobinopathies is high in low-income countries such as Sub Saharan region and South East Asia. 85% of the affected population in the U.S. and Europe has ancestral base in these regions.

Governments are collaborating with local institutes to undertake awareness programs for curbing the effect of hemoglobinopathies-related mortality rate. For instance, Thalassemia Data Collection Project and Registry and Surveillance System for Hemoglobinopathies (RuSH) projects were started in 2010 by the Centers for Disease Control and Prevention (CDC).

Low level of hygiene, insufficient healthcare infrastructure, and lesser awareness levels are some key factors attributing to increase in base of target population in low-income regions such as South East Asia, Mediterranean basin, and Africa.

Further key findings from the study suggest:

The market for Sickle Cell Disease (SCD) was the largest with revenue valued at over USD 2,290.0 million in 2014. Rising prevalence of hemoglobinopathies and presence of strong product pipeline for sickle cell anemia such as HQK-1001 and Luspatercept are growth promoting factors of this market.

Genetic testing for diagnosis of sickle cell disorders is expected to witness lucrative growth over the forecast period. It is estimated to grow at a CAGR of around 7.0%. Increasing awareness levels among people coupled with government programs such as the National Sickle Cell Disease Control Program conducted by the WHO in Africa are anticipated to enhance the usage rates for diagnostic tests pertaining to SCD.

Hydroxyurea was one of the dominating segments of the SCD therapy market owing to the presence of the FDA-approved drugs such as Droxia and Hydrea by Bristol Myers Squib. SCD. Thalassemia market holds an extensive product portfolio in pipeline and their expected commercialization is anticipated to drive market growth. For instance, The Ellis Lab is developing a gene therapy for SCD in collaboration with Dr. Victor Garcia

Blood tests including cell blood count and iron studies are the widely used techniques for diagnosis of thalassemia. On the other hand, pre-implant genetic testing is estimated to grow at lucrative growth rate over 8.5% in the next six years owing to rising base of health conscious population and increasing healthcare expenditure.

The market for blood transfusion was the largest with revenues valued at over USD 1,408.0 million in therapeutic segment owing to, high acceptance level of this treatment option and significant success rate. It is estimated that around 85% of infants below five years suffering from thalassemia die due to insufficient blood transfusion.

North America dominated the overall hemoglobinopathies market in terms of revenue in 2014 at over USD 1,212.0 million. Growing prevalence of blood disorders, favorable government programs, and high level of awareness among healthcare professionals and patients for hemoglobinopathies-related genetic testing are factors attributing to the major share of this market.

Asia Pacific market is expected to witness lucrative growth over the forecast period with a CAGR of over 10% owing to the presence of high unmet clinical needs, improving healthcare infrastructure, and rising economic levels. Moreover, introduction of low-cost diagnostic alternatives will enhance adoption rates for hemoglobinopathies diagnostics market.


Chapter 1 Methodology and Scope
1.1 Research Methodology
1.2 Research Scope & Assumptions
1.3 List of Data Sources
1.4 Known, Unknown variables & target segment
Chapter 2 Executive Summary
Chapter 3 Hemoglobinopathies Industry Outlook
3.1 Market segmentation
3.2 Market size and growth prospects
3.3 Hemoglobinopathies : Market dynamics
3.3.1 Market Driver Analysis
3.3.1 Market Restraint Analysis
3.4 Key opportunity analysis, by type- 2014
3.5 Industry analysis Porter’s
3.6 Hemoglobinopathies : PESTEL Analysis
3.7 Hemoglobinopathies Market : Government Regulations
3.7.1 Sickle Cell Disease (SCD) drug development
3.7.2 Drug development for Thalassemia
3.8 Hemoglobinopathies Market: Need Gap Analysis
3.8.1 Prevalence
3.8.2 Treatment efficacy
3.8.3 Therapeutic gap
Chapter 4 Hemoglobinopathies Therapy Outlook
4.1 Hemoglobinopathies market share by therapy, 2014 & 2022
4.2 Thalassemia therapy
4.2.1 Thalassemia therapy market, 2012 - 2022 (USD Million)
4.2.2 Alpha thalassemia therapy
4.2.2.1 Alpha thalassemia therapy market, 2012 - 2022 (USD Million)
4.2.3 Beta thalassemia therapy
4.2.3.1 Beta thalassemia therapy market, 2012 - 2022 (USD Million)
4.3 Sickle Cell Disease (SCD) therapy
4.3.1 Sickle Cell Disease (SCD) therapy market, 2012 - 2022 (USD Million)
4.4 Other therapy
4.4.1 Other haemoglobin variants therapy market, 2012 - 2022 (USD Million)
Chapter 5 Hemoglobinopathies Diagnosis Outlook
5.1 Hemoglobinopathies market share by diagnosis, 2014 & 2022
5.2 Thalassemia diagnosis
5.2.1 Thalassemia diagnosis market, 2012 - 2022 (USD Million)
5.2.2 Alpha thalassemia diagnosis
5.2.2.1 Alpha thalassemia diagnosis market, 2012 - 2022 (USD Million)
5.2.3 Beta thalassemia diagnosis
5.2.3.1 Beta thalassemia diagnosis market, 2012 - 2022 (USD Million)
5.3 Sickle Cell Disease (SCD) diagnosis
5.3.1 Sickle Cell Disease (SCD) diagnosis market, 2012 - 2022 (USD Million)
5.4 Other hemoglobin variants
5.4.1 Other haemoglobin variants market, 2012 - 2022 (USD Million)
Chapter 6 Hemoglobinopathies Regional Outlook
6.1 Hemoglobinopathies market Share by Region, 2014 & 2022
6.2 North America
6.2.2 U.S.
6.2.4 Canada
6.3 Europe
6.3.1 Europe Hemoglobinopathies Market, 2012 - 2022 (USD Million)
6.3.2 UK
6.3.3 UK Hemoglobinopathies Market, 2012 - 2022 (USD Million)
6.3.4 Germany
6.3.5 Germany Hemoglobinopathies Market, 2012 - 2022 (USD Million)
6.4 Asia Pacific
6.4.1 Asia Pacific Hemoglobinopathies Market, 2012 - 2022 (USD Million)
6.4.2 Japan
6.4.4 China
6.4.5 China Hemoglobinopathies Market, 2012 - 2022 (USD Million)
6.5 Latin America
6.5.1 Latin America Hemoglobinopathies Market, 2012 - 2022 (USD Million)
6.5.2 Brazil
6.5.3 Brazil Hemoglobinopathies Market, 2012 - 2022 (USD Million)
6.5.4 Mexico
6.5.5 Mexico Hemoglobinopathies Market, 2012 - 2022 (USD Million)
6.6 MEA
6.6.2 South Africa
6.6.3 South Africa Hemoglobinopathies Market, 2012 - 2022 (USD Million)
Chapter 7 Competitive Landscape
7.1 Gamida Cell
7.1.1 Company Overview
7.1.2 Financial Performance
7.1.3 Product Benchmarking
7.1.4 Strategic Initiatives
7.2 Alnylam Pharmaceuticals
7.2.1 Company Overview
7.2.2 Financial Performance
7.2.3 Product Benchmarking
7.2.4 Strategic Initiatives
7.3 Biogen Idec
7.3.1 Company Overview
7.3.2 Financial Performance
7.3.3 Product Benchmarking
7.3.4 Strategic Initiatives
7.4 Sangamo BioSciences Inc.
7.4.1 Company Overview
7.4.2 Financial Performance
7.4.3 Product Benchmarking
7.4.4 Strategic Initiatives
7.5 Genetix Pharmaceuticals/Bluebird Bio
7.5.1 Company Overview
7.5.2 Financial Performance
7.5.3 Product Benchmarking
7.5.4 Strategic Initiatives
7.6 Global Blood Therapeutics Inc.
7.6.1 Company Overview
7.6.2 Financial Performance
7.6.3 Product Benchmarking
7.6.4 Strategic Initiatives
7.7 Pfizer Inc.
7.7.1 Company Overview
7.7.2 Financial Performance
7.7.3 Product Benchmarking
7.7.4 Strategic Initiatives
7.8 Mast Therapeutics
7.8.1 Company Overview
7.8.2 Financial Performance
7.8.3 Product Benchmarking
7.8.4 Strategic Initiatives
7.9 Emmaus Life Sciences, Inc.
7.9.1 Company Overview
7.9.2 Financial Performance
7.9.3 Product Benchmarking
7.9.4 Strategic Initiatives
7.10 Prolong Pharmaceuticals
7.10.1 Company Overview
7.10.2 Financial Performance
7.10.3 Product Benchmarking
7.10.4 Strategic Initiatives
7.11 Celgene Corporation
7.11.1 Company Overview
7.11.2 Financial Performance
7.11.3 Product Benchmarking
7.11.4 Strategic Initiatives
7.12 HemaQuest Pharmaceuticals
7.12.1 Company Overview
7.12.2 Financial Performance
7.12.3 Product Benchmarking
7.12.4 Strategic Initiatives

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