Interleukin 1 (IL1) - Pipeline Review, H1 2018
According to the recently published report 'Interleukin 1 (IL1) - Pipeline Review, H1 2018'; Interleukin 1 (IL1) pipeline Target constitutes close to 22 molecules. Out of which approximately 21 molecules are developed by companies and remaining by the universities/institutes.
Interleukin 1 (IL1) - Interleukin-1 is a cytokine which plays an important role regulation of immune and inflammatory responses. It helps leukocytes pass through blood vessel walls to sites of infection and causes fever by affecting areas of the brain that control body temperature. There are two forms of interleukin-1, alpha and beta. IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity.
The report 'Interleukin 1 (IL1) - Pipeline Review, H1 2018' outlays comprehensive information on the Interleukin 1 (IL1) targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA) and molecule type; that are being developed by Companies / Universities.
It also reviews key players involved in Interleukin 1 (IL1) targeted therapeutics development with respective active and dormant or discontinued projects. Currently, The molecules developed by companies in Pre-Registration, Filing rejected/Withdrawn, Phase III, Phase II, Phase I, Preclinical and Discovery stages are 1, 1, 1, 6, 1, 10 and 1 respectively. Similarly, the universities portfolio in Preclinical stages comprises 1 molecules, respectively.
Report covers products from therapy areas Cardiovascular, Immunology, Metabolic Disorders, Oncology, Dermatology, Musculoskeletal Disorders, Ear Nose Throat Disorders, Gastrointestinal, Genetic Disorders, Central Nervous System and Genito Urinary System And Sex Hormones which include indications Gouty Arthritis (Gout), Non-Small Cell Lung Cancer, Epidermolysis Bullosa, Inflammation, Atherosclerosis, Behcet Disease, Familial Mediterranean Fever, Type 2 Diabetes, Acne Vulgaris, Atopic Dermatitis, Autoimmune Disorders, Bladder Cancer, Bullous Pemphigoid, Cancer Anorexia-Cachexia Syndrome, Cardiovascular Risk Factors, Cervical Cancer, Colorectal Cancer, Diabetes, Esophageal Cancer, Fallopian Tube Cancer, Hearing Disorders, Hidradenitis Suppurativa, Hypercholesterolemia, Inflammatory Bowel Disease, Kidney Fibrosis, Liver Fibrosis, Lymphoma, Metastatic Colorectal Cancer, Mevalonate Kinase Deficiency (Hyperimmunoglobulin D Syndrome (HIDS)), Muckle-Wells Syndrome, Myocardial Infarction, Neonatal Onset Multisystem Inflammatory Disease, Ovarian Cancer, Pain, Pancreatic Cancer, Pericarditis, Plaque Psoriasis (Psoriasis Vulgaris), Prostate Cancer, Restenosis, Rheumatoid Arthritis, Rhinitis, Sarcoidosis, Skin Inflammation, Skin Ulcers, Systemic Idiopathic Juvenile Arthritis and Tumor Necrosis Factor Receptor-Associated Periodic Syndrome (Familial Hibernian Fever).
Note: Certain content / sections in the pipeline guide may be removed or altered based on the availability and relevance of data.
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