Histone Deacetylase 8 (Histone Deacetylase Like 1 or HDAC8 or EC 18.104.22.168) - Pipeline Review, H2 2018
According to the recently published report 'Histone Deacetylase 8 - Pipeline Review, H2 2018'; Histone Deacetylase 8 (Histone Deacetylase Like 1 or HDAC8 or EC 22.214.171.124) pipeline Target constitutes close to 6 molecules.
Histone Deacetylase 8 (Histone Deacetylase Like 1 or HDAC8 or EC 126.96.36.199) - Histone deacetylase 8 is an enzyme encoded by the HDAC8 gene. It is responsible for the deacetylation of lysine residues on the N-terminal part of the core histones. It plays an important role in transcriptional regulation, cell cycle progression and developmental events.
The report 'Histone Deacetylase 8 - Pipeline Review, H2 2018' outlays comprehensive information on the Histone Deacetylase 8 (Histone Deacetylase Like 1 or HDAC8 or EC 188.8.131.52) targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA) and molecule type; that are being developed by Companies / Universities.
It also reviews key players involved in Histone Deacetylase 8 (Histone Deacetylase Like 1 or HDAC8 or EC 184.108.40.206) targeted therapeutics development with respective active and dormant or discontinued projects. Currently, The molecules developed by companies in Phase III, IND/CTA Filed and Preclinical stages are 1, 1 and 4 respectively.
Report covers products from therapy areas Oncology, Central Nervous System, Gastrointestinal, Infectious Disease and Musculoskeletal Disorders which include indications Breast Cancer, Colon Cancer, Non-Small Cell Lung Cancer, Prostate Cancer, Adenoid Cystic Carcinoma (ACC), Alzheimer's Disease, Anaplastic Large Cell Lymphoma (ALCL), Angioimmunoblastic T-Cell Lymphoma (AITL)/Immunoblastic Lymphadenopathy, B-Cell Non-Hodgkin Lymphoma, Bladder Cancer, Bone Disorders, Diffuse Large B-Cell Lymphoma, Follicular Lymphoma, Glioblastoma Multiforme (GBM), Hodgkin Lymphoma (B-Cell Hodgkin Lymphoma), Human Immunodeficiency Virus (HIV) Infections (AIDS), Liver Cancer, Liver Fibrosis, Lung Cancer, Mantle Cell Lymphoma, Marginal Zone B-cell Lymphoma, Melanoma, Mycosis Fungoides, Natural Killer Cell Lymphomas, Neurodegenerative Diseases, Non-Hodgkin Lymphoma, Peripheral T-Cell Lymphomas (PTCL), Refractory Multiple Myeloma, Relapsed Multiple Myeloma and Renal Cell Carcinoma.
Note: Certain content / sections in the pipeline guide may be removed or altered based on the availability and relevance of data.
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