Glucagon Like Peptide 2 Receptor (GLP2R) - Drugs in Development, 2021
Summary
Glucagon Like Peptide 2 Receptor (GLP2R) - Glucagon-like peptide 2 receptor (GLP-2R) is a protein encoded by the GLP2R gene. GLP2R, a G protein-coupled receptor superfamily member is expressed in the gut. GLP2 stimulates intestinal growth and up regulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. GLP2 prevents intestinal hypoplasia resulting from total parenteral nutrition.
Glucagon Like Peptide 2 Receptor (GLP2R) pipeline Target constitutes close to 15 molecules. Out of which approximately 14 molecules are developed by companies and remaining by the universities/institutes. The molecules developed by companies in Phase III, Phase I, Preclinical, Discovery and Unknown stages are 2, 3, 7, 1 and 1 respectively. Similarly, the universities portfolio in Discovery stages comprises 1 molecules, respectively. Report covers products from therapy areas Gastrointestinal, Immunology, Metabolic Disorders, Musculoskeletal Disorders and Other Diseases which include indications Short Bowel Syndrome, Graft Versus Host Disease (GVHD), Crohn's Disease (Regional Enteritis), Inflammation, Multiple Organ Failure (Multiple Organ Dysfunction Syndrome), Osteoporosis, Unspecified Gastrointestinal Disorders and Unspecified Metabolic Disorders.
The latest report Glucagon Like Peptide 2 Receptor - Drugs In Development, 2021, outlays comprehensive information on the Glucagon Like Peptide 2 Receptor (GLP2R) targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA) and molecule type. It also reviews key players involved in Glucagon Like Peptide 2 Receptor (GLP2R) targeted therapeutics development with respective active and dormant or discontinued projects.
The report is built using data and information sourced from proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources.
Note: Certain content / sections in the pipeline guide may be removed or altered based on the availability and relevance of data.
Scope
- The report provides a snapshot of the global therapeutic landscape for Glucagon Like Peptide 2 Receptor (GLP2R)
- The report reviews Glucagon Like Peptide 2 Receptor (GLP2R) targeted therapeutics under development by companies and universities/research institutes based on information derived from company and industry-specific sources
- The report covers pipeline products based on various stages of development ranging from pre-registration till discovery and undisclosed stages
- The report features descriptive drug profiles for the pipeline products which includes, product description, descriptive MoA, R&D brief, licensing and collaboration details & other developmental activities
- The report reviews key players involved in Glucagon Like Peptide 2 Receptor (GLP2R) targeted therapeutics and enlists all their major and minor projects
- The report assesses Glucagon Like Peptide 2 Receptor (GLP2R) targeted therapeutics based on mechanism of action (MoA), route of administration (RoA) and molecule type
- The report summarizes all the dormant and discontinued pipeline projects
- The report reviews latest news and deals related to Glucagon Like Peptide 2 Receptor (GLP2R) targeted therapeutics
Reasons to Buy- Gain strategically significant competitor information, analysis, and insights to formulate effective R&D strategies
- Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage
- Identify and understand the targeted therapy areas and indications for Glucagon Like Peptide 2 Receptor (GLP2R)Identify the use of drugs for target identification and drug repurposing
- Identify potential new clients or partners in the target demographic
- Develop strategic initiatives by understanding the focus areas of leading companies
- Plan mergers and acquisitions effectively by identifying key players and it’s most promising pipeline therapeutics
- Devise corrective measures for pipeline projects by understanding Glucagon Like Peptide 2 Receptor (GLP2R) development landscape
- Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope
- Introduction
- Global Markets Direct Report Coverage
- Glucagon Like Peptide 2 Receptor (GLP2R) - Overview
- Glucagon Like Peptide 2 Receptor (GLP2R) - Therapeutics Development
- Products under Development by Stage of Development
- Products under Development by Therapy Area
- Products under Development by Indication
- Products under Development by Companies
- Products under Development by Universities/Institutes
- Glucagon Like Peptide 2 Receptor (GLP2R) - Therapeutics Assessment
- Assessment by Mechanism of Action
- Assessment by Route of Administration
- Assessment by Molecule Type
- Glucagon Like Peptide 2 Receptor (GLP2R) - Companies Involved in Therapeutics Development
- 9 Meters Biopharma Inc
- Applied Molecular Transport Inc
- Bainan Biotech ApS
- Entera Bio Ltd
- Hanmi Pharmaceuticals Co Ltd
- Huons Global Co Ltd
- OPKO Health Inc
- PhaseBio Pharmaceuticals Inc
- Sosei Group Corp
- Tasly Pharmaceutical Group Co Ltd
- VectivBio Holding AG
- Zealand Pharma AS
- Glucagon Like Peptide 2 Receptor (GLP2R) - Drug Profiles
- apraglutide - Drug Profile
- Product Description
- Mechanism Of Action
- R&D Progress
- dapiglutide - Drug Profile
- Product Description
- Mechanism Of Action
- R&D Progress
- Drugs to Agonize GIP and GLP-2 for Osteoporosis - Drug Profile
- Product Description
- Mechanism Of Action
- R&D Progress
- Fusion Protein to Agonize GLP2R for Short Bowel Syndrome - Drug Profile
- Product Description
- Mechanism Of Action
- R&D Progress
- Fusion Protein to Agonize GLP2R for Short Bowel Syndrome - Drug Profile
- Product Description
- Mechanism Of Action
- R&D Progress
- glepaglutide - Drug Profile
- Product Description
- Mechanism Of Action
- R&D Progress
- GXG-8 - Drug Profile
- Product Description
- Mechanism Of Action
- R&D Progress
- HL-06 - Drug Profile
- Product Description
- Mechanism Of Action
- R&D Progress
- HM-15912 - Drug Profile
- Product Description
- Mechanism Of Action
- R&D Progress
- MOD-1501 - Drug Profile
- Product Description
- Mechanism Of Action
- R&D Progress
- NB-1002 - Drug Profile
- Product Description
- Mechanism Of Action
- R&D Progress
- Peptide to Agonize GLP2R for Intestinal Diseases - Drug Profile
- Product Description
- Mechanism Of Action
- R&D Progress
- Peptide to Agonize GLP2R for Unspecified Gastrointestinal Diseases and Unspecified Metabolic Diseases - Drug Profile
- Product Description
- Mechanism Of Action
- R&D Progress
- teduglutide - Drug Profile
- Product Description
- Mechanism Of Action
- R&D Progress
- teduglutide - Drug Profile
- Product Description
- Mechanism Of Action
- R&D Progress
- teduglutide - Drug Profile
- Product Description
- Mechanism Of Action
- R&D Progress
- Glucagon Like Peptide 2 Receptor (GLP2R) - Dormant Products
- Glucagon Like Peptide 2 Receptor (GLP2R) - Discontinued Products
- Glucagon Like Peptide 2 Receptor (GLP2R) - Product Development Milestones
- Featured News & Press Releases
- Aug 19, 2021: Zealand Pharma announces first patient dosed in EASE-SBS 4 phase 3b trial assessing glepaglutide in patients with short bowel syndrome
- Jun 29, 2021: Zealand Pharma to present data on glepaglutide at the 17th Congress of the Intestinal Rehabilitation and Transplantation Association (CIRTA)
- Jun 24, 2021: VectivBio receives FDA Orphan Drug Designation for apraglutide for acute graft-versus-host disease
- Jun 23, 2021: Takeda Pharmaceutical : Obtaining manufacturing and marketing approval for Revestive, the first treatment for short bowel syndrome in Japan
- Jun 15, 2021: VectivBio announces first patient dosed in metabolic balance study of apraglutide in colon-in-continuity patients with short bowel syndrome with intestinal failure
- Apr 07, 2021: Hanmi's short bowel syndrome drug gets FDA fast-track status
- Feb 03, 2021: VectivBio announces first patient dosed in pivotal phase 3 trial of Apraglutide for the treatment of short bowel syndrome
- Feb 03, 2021: VectivBio announces first patient dosed in pivotal phase 3 trial of Apraglutide for the treatment of short bowel syndrome
- Dec 09, 2020: 9 Meters Biopharma receives orphan drug designation for NM-003, a proprietary long-acting GLP-2, for prevention of acute graft versus host disease (aGvHD)
- Jul 01, 2020: Hanmi Pharm’s short-bowel syndrome drug wins FDA’s rare pediatric disease status
- Feb 10, 2020: The Scottish Medicines Consortium advises on newly licensed medicine Revestive for use by NHSScotland
- Jun 26, 2019: Zealand Pharma doses first subject in Phase 1 clinical trial with potential next generation dual-acting peptide therapeutic for short bowel syndrome
- May 17, 2019: Therachon to present data from ongoing Phase II Study of Apraglutide for Short Bowel Syndrome at Digestive Disease Week
- May 17, 2019: U.S. FDA approves GATTEX (teduglutide) for children 1 year of age and older with Short Bowel Syndrome
- May 07, 2019: Zealand Pharma enrolls first patient in Phase 3 extension study of glepaglutide for treatment for short bowel syndrome
- Appendix
- Methodology
- Coverage
- Secondary Research
- Primary Research
- Expert Panel Validation
- Contact Us
- Disclaimer
- List of Tables
- Number of Products under Development by Stage of Development, 2021
- Number of Products under Development by Therapy Areas, 2021
- Number of Products under Development by Indication, 2021
- Number of Products under Development by Companies, 2021
- Products under Development by Companies, 2021
- Products under Development by Companies, 2021 (Contd..1)
- Number of Products under Investigation by Universities/Institutes, 2021
- Products under Investigation by Universities/Institutes, 2021
- Number of Products by Stage and Mechanism of Actions, 2021
- Number of Products by Stage and Route of Administration, 2021
- Number of Products by Stage and Molecule Type, 2021
- Pipeline by 9 Meters Biopharma Inc, 2021
- Pipeline by Applied Molecular Transport Inc, 2021
- Pipeline by Bainan Biotech ApS, 2021
- Pipeline by Entera Bio Ltd, 2021
- Pipeline by Hanmi Pharmaceuticals Co Ltd, 2021
- Pipeline by Huons Global Co Ltd, 2021
- Pipeline by OPKO Health Inc, 2021
- Pipeline by PhaseBio Pharmaceuticals Inc, 2021
- Pipeline by Sosei Group Corp, 2021
- Pipeline by Tasly Pharmaceutical Group Co Ltd, 2021
- Pipeline by VectivBio Holding AG, 2021
- Pipeline by Zealand Pharma AS, 2021
- Dormant Projects, 2021
- Discontinued Products, 2021
- List of Figures
- Number of Products under Development by Stage of Development, 2021
- Number of Products under Development by Therapy Areas, 2021
- Number of Products under Development by Top 10 Indications, 2021
- Number of Products by Stage and Mechanism of Actions, 2021
- Number of Products by Routes of Administration, 2021
- Number of Products by Stage and Routes of Administration, 2021
- Number of Products by Molecule Types, 2021
- Number of Products by Stage and Molecule Types, 2021