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Amyloidosis - Pipeline Review, H2 2015

Amyloidosis - Pipeline Review, H2 2015

Summary

Global Markets Direct’s, ‘Amyloidosis - Pipeline Review, H2 2015’, provides an overview of the Amyloidosis’s therapeutic pipeline.

This report provides comprehensive information on the therapeutic development for Amyloidosis, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for Amyloidosis and special features on late-stage and discontinued projects.

Global Markets Direct’s report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct’s proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct’s team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis.

The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products.

Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease.

Scope

  • The report provides a snapshot of the global therapeutic landscape of Amyloidosis
  • The report reviews key pipeline products under drug profile section which includes, product description, MoA and R&D brief, licensing and collaboration details & other developmental activities
  • The report reviews key players involved in the therapeutics development for Amyloidosis and enlists all their major and minor projects
  • The report summarizes all the dormant and discontinued pipeline projects
  • A review of the Amyloidosis products under development by companies and universities/research institutes based on information derived from company and industry-specific sources
  • Pipeline products coverage based on various stages of development ranging from pre-registration till discovery and undisclosed stages
  • A detailed assessment of monotherapy and combination therapy pipeline projects
  • Coverage of the Amyloidosis pipeline on the basis of target, MoA, route of administration and molecule type
  • Latest news and deals relating related to pipeline products
Reasons to buy
  • Provides strategically significant competitor information, analysis, and insights to formulate effective R&D development strategies
  • Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage
  • Develop strategic initiatives by understanding the focus areas of leading companies
  • Identify and understand important and diverse types of therapeutics under development for Amyloidosis
  • Plan mergers and acquisitions effectively by identifying key players of the most promising pipeline
  • Devise corrective measures for pipeline projects by understanding Amyloidosis pipeline depth and focus of Indication therapeutics
  • Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope
  • Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline


Introduction
Global Markets Direct Report Coverage
Amyloidosis Overview
Therapeutics Development
Pipeline Products for Amyloidosis - Overview
Pipeline Products for Amyloidosis - Comparative Analysis
Amyloidosis - Therapeutics under Development by Companies
Amyloidosis - Therapeutics under Investigation by Universities/Institutes
Amyloidosis - Pipeline Products Glance
Late Stage Products
Clinical Stage Products
Early Stage Products
Amyloidosis - Products under Development by Companies
Amyloidosis - Products under Investigation by Universities/Institutes
Amyloidosis - Companies Involved in Therapeutics Development
Alnylam Pharmaceuticals, Inc.
Arcturus Therapeutics, Inc
Bellus Health Inc.
Bsim2
Celgene Corporation
GlaxoSmithKline Plc
Isis Pharmaceuticals, Inc.
Millennium Pharmaceuticals, Inc.
Onyx Pharmaceuticals, Inc.
Pfizer Inc.
ProteoTech, Inc.
Prothena Corporation Plc
SOM Innovation Biotech SL
Amyloidosis - Therapeutics Assessment
Assessment by Monotherapy Products
Assessment by Combination Products
Assessment by Target
Assessment by Mechanism of Action
Assessment by Route of Administration
Assessment by Molecule Type
Drug Profiles
ALN-TTRsc02 - Drug Profile
Product Description
Mechanism of Action
R&D Progress
Antisense RNAi Oligonucleotides to Inhibit Amyloid Precursor Protein for Amyloidosis - Drug Profile
Product Description
Mechanism of Action
R&D Progress
carfilzomib - Drug Profile
Product Description
Mechanism of Action
R&D Progress
CLR-01 - Drug Profile
Product Description
Mechanism of Action
R&D Progress
eprodisate disodium - Drug Profile
Product Description
Mechanism of Action
R&D Progress
GSK-2315698 + GSK-2398852 - Drug Profile
Product Description
Mechanism of Action
R&D Progress
GSK-2398852 - Drug Profile
Product Description
Mechanism of Action
R&D Progress
ISIS-TTRRx - Drug Profile
Product Description
Mechanism of Action
R&D Progress
ixazomib citrate - Drug Profile
Product Description
Mechanism of Action
R&D Progress
LUNAR-101 - Drug Profile
Product Description
Mechanism of Action
R&D Progress
LUNAR-102 - Drug Profile
Product Description
Mechanism of Action
R&D Progress
Monoclonal Antibody for Amyloidosis - Drug Profile
Product Description
Mechanism of Action
R&D Progress
Monoclonal Antibody to Inhibit ATTR for Familial Amyloid Polyneuropathy - Drug Profile
Product Description
Mechanism of Action
R&D Progress
NEOD-001 - Drug Profile
Product Description
Mechanism of Action
R&D Progress
NPT-005 - Drug Profile
Product Description
Mechanism of Action
R&D Progress
patisiran - Drug Profile
Product Description
Mechanism of Action
R&D Progress
pomalidomide - Drug Profile
Product Description
Mechanism of Action
R&D Progress
PTI-110 - Drug Profile
Product Description
Mechanism of Action
R&D Progress
revusiran - Drug Profile
Product Description
Mechanism of Action
R&D Progress
Small Molecules for AL Amyloidosis - Drug Profile
Product Description
Mechanism of Action
R&D Progress
Small Molecules to Inhibit Transthyretin for Familial Amyloid Polyneuropathy - Drug Profile
Product Description
Mechanism of Action
R&D Progress
Small Molecules to Inhibit Transthyretin Related Amyloid Protein for Familial Amyloidotic Cardiomyopathy - Drug Profile
Product Description
Mechanism of Action
R&D Progress
Small Molecules to Inhibit Transthyretin Related Amyloid Protein for Familial Amyloidotic Polyneuropathy - Drug Profile
Product Description
Mechanism of Action
R&D Progress
tafamidis meglumine - Drug Profile
Product Description
Mechanism of Action
R&D Progress
tolcapone - Drug Profile
Product Description
Mechanism of Action
R&D Progress
Amyloidosis - Recent Pipeline Updates
Amyloidosis - Dormant Projects
Amyloidosis - Product Development Milestones
Featured News & Press Releases
Sep 28, 2015: Alnylam and Collaborators Report First-Ever Evidence that Patisiran Reduces Pathogenic, Misfolded Transthyretin Monomers and Oligomers in TTR-Mediated Amyloidosis Patients with Familial Amyloidotic Polyneuropathy
Aug 12, 2015: BELLUS Health narrows timelines for the Phase III study for KIACTA
Jul 20, 2015: Alnylam Initiates Phase 3 Open Label Extension Study with Patisiran, an Investigational RNAi Therapeutic Targeting Transthyretin for the Treatment of TTR-Mediated Amyloidosis
Jun 12, 2015: Opportunity to Improve Diagnosis and Treatment of Systemic Amyloidosis Highlighted in Patient Experience Survey Presented at the 20th Congress of the European Hematology Association
Jun 12, 2015: Prothena's NEOD001 Protein Immunotherapy Clinical Data Highlighted in Oral Presentation at the 20th Congress of the European Hematology Association
Jun 02, 2015: Prothena Presents Compelling New Data From Ongoing Phase 1/2 Study of NEOD001 in Patients With AL Amyloidosis at 2015 ASCO Annual Meeting
May 21, 2015: Prothena Announces Presentation of Clinical Data From the Ongoing Phase 1/2 NEOD001 Study and Systemic Amyloidosis Patient Survey Results at 20th Congress of the European Hematology Association
May 20, 2015: Alnylam Receives Orphan Drug Designation from the United States Food & Drug Administration for Revusiran, an Investigational RNAi Therapeutic for the Treatment of Transthyretin (TTR)-Mediated Amyloidosis
May 13, 2015: Prothena to Present Updated Clinical Data From Ongoing Phase 1/2 Study of NEOD001 at 2015 ASCO Annual Meeting
Apr 22, 2015: Isis Pharmaceuticals Reports Positive Data From ISIS-TTR Rx in Patients With TTR Amyloidosis
Appendix
Methodology
Coverage
Secondary Research
Primary Research
Expert Panel Validation
Contact Us
Disclaimer
List of Tables
Number of Products under Development for Amyloidosis, H2 2015
Number of Products under Development for Amyloidosis - Comparative Analysis, H2 2015
Number of Products under Development by Companies, H2 2015
Number of Products under Investigation by Universities/Institutes, H2 2015
Comparative Analysis by Late Stage Development, H2 2015
Comparative Analysis by Clinical Stage Development, H2 2015
Comparative Analysis by Early Stage Development, H2 2015
Products under Development by Companies, H2 2015
Products under Development by Companies, H2 2015 (Contd..1)
Products under Investigation by Universities/Institutes, H2 2015
Amyloidosis - Pipeline by Alnylam Pharmaceuticals, Inc., H2 2015
Amyloidosis - Pipeline by Arcturus Therapeutics, Inc, H2 2015
Amyloidosis - Pipeline by Bellus Health Inc., H2 2015
Amyloidosis - Pipeline by Bsim2, H2 2015
Amyloidosis - Pipeline by Celgene Corporation, H2 2015
Amyloidosis - Pipeline by GlaxoSmithKline Plc, H2 2015
Amyloidosis - Pipeline by Isis Pharmaceuticals, Inc., H2 2015
Amyloidosis - Pipeline by Millennium Pharmaceuticals, Inc., H2 2015
Amyloidosis - Pipeline by Onyx Pharmaceuticals, Inc., H2 2015
Amyloidosis - Pipeline by Pfizer Inc., H2 2015
Amyloidosis - Pipeline by ProteoTech, Inc., H2 2015
Amyloidosis - Pipeline by Prothena Corporation Plc, H2 2015
Amyloidosis - Pipeline by SOM Innovation Biotech SL, H2 2015
Assessment by Monotherapy Products, H2 2015
Assessment by Combination Products, H2 2015
Number of Products by Stage and Target, H2 2015
Number of Products by Stage and Mechanism of Action, H2 2015
Number of Products by Stage and Route of Administration, H2 2015
Number of Products by Stage and Molecule Type, H2 2015
Amyloidosis Therapeutics - Recent Pipeline Updates, H2 2015
Amyloidosis - Dormant Projects, H2 2015
List of Figures
Number of Products under Development for Amyloidosis, H2 2015
Number of Products under Development for Amyloidosis - Comparative Analysis, H2 2015
Number of Products under Development by Companies, H2 2015
Number of Products under Investigation by Universities/Institutes, H2 2015
Comparative Analysis by Late Stage Development, H2 2015
Comparative Analysis by Clinical Stage Development, H2 2015
Comparative Analysis by Early Stage Products, H2 2015
Assessment by Monotherapy Products, H2 2015
Number of Products by Top 10 Targets, H2 2015
Number of Products by Stage and Top 10 Targets, H2 2015
Number of Products by Top 10 Mechanism of Actions, H2 2015
Number of Products by Stage and Top 10 Mechanism of Actions, H2 2015
Number of Products by Top 10 Routes of Administration, H2 2015
Number of Products by Stage and Top 10 Routes of Administration, H2 2015
Number of Products by Top 10 Molecule Types, H2 2015
Number of Products by Stage and Top 10 Molecule Types, H2 2015

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