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Deep Brain Stimulation Devices

Deep Brain Stimulation Devices

This report analyzes the worldwide markets for Deep Brain Stimulation Devices in US$ Thousand. The report provides separate comprehensive analytics for the US, Canada, Japan, Europe, Asia-Pacific, Latin America, and Rest of World. Annual estimates and forecasts are provided for the period 2016 through 2024. Also, a five-year historic analysis is provided for these markets. Market data and analytics are derived from primary and secondary research. Company profiles are primarily based on public domain information including company URLs. The report profiles 21 companies including many key and niche players such as -

Abbott Laboratories
Aleva Neurotherapeutics SA
Boston Scientific Corp.
Deep Brain Innovations, LLC
Medtronic Plc
Beijing Pins Medical Co., Ltd.

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I. INTRODUCTION, METHODOLOGY & PRODUCT DEFINITIONS
Study Reliability and Reporting Limitations
Disclaimers
Data Interpretation & Reporting Level
Quantitative Techniques & Analytics
Product Definitions and Scope of Study
II. EXECUTIVE SUMMARY
1. INDUSTRY OVERVIEW
A Prelude
Introduction to Deep Brain Stimulation Devices
Deep Brain Stimulation – Then and Now
Global Market Overview
Competitive Landscape
Table 1: Global DBS Market by Leading Player (2016 & 2017E): Market Share Breakdown of Revenues for Medtronic, Boston Scientific, and Abbott (includes corresponding Graph/Chart)
Table 2: The US DBS Market by Leading Player (2016 & 2017E): Market Share Breakdown of Revenues for Medtronic, Boston Scientific, and Abbott (includes corresponding Graph/Chart)
Table 3: Rest of World (Exc. US) DBS Market by Leading Player (2016 & 2017E): Market Share Breakdown of Revenues for Medtronic, Boston Scientific, and Abbott (includes corresponding Graph/Chart)
Select Available Deep Brain Stimulation Devices Available in the Market
Recent Advancements and the Way Ahead
2. MARKET DYNAMICS
DBS Market Driven by the Minimally Invasive Treatment Conferred
Hybrid DBS Devices Witness Increased Demand
Aging Population and Rising Disease Prevalence: The Cornerstone for DBS
Table 4: Global Population Statistics for the 65+ Age Group (2016) (includes corresponding Graph/Chart)
Table 5: Life Expectancy for Select Countries in Number of Years: 2016 (includes corresponding Graph/Chart)
Rising Healthcare Expenditure Induces Momentum in the Market
Table 6: Healthcare Spending as % of GDP by Region (2016) (includes corresponding Graph/Chart)
Novel Applications Bode Tremendous Prospects
Technical Advancements Aid in Progress of DBS
Still Questions Arise on the Current Pace of Innovation
Closed-Loop Functionality Gaining Favor over Open-Loop in Neurostimulation
Investigational DBS Device Inches towards Closed-Loop Functionality
Promising Targets for PIGD
Steering Brain Stimulation – An Emerging Concept in DBS
Novel Leads Target Selective and Fractional Stimulation
Researchers Devise Temporal Interference Method for Non-Invasive Deep Brain Stimulation
Researchers Develop New Pulse Pattern to Improve DBS for Parkinson’s
Researchers Eye Deep Brain Stimulation to Treat Depression
Role of DBS in Managing Movement Disorders among Children
Novel Electrode Configurations Aid in Localization and Side Effect Reduction
Nanotechnology – The Future of DBS Electrodes
On-Demand Stimulators Promise to Contribute to Superior Therapeutic Outcomes
Sophisticated Neurostimulators
Advances in Programming Promise Ease of Treatment
Visual Depiction of Electrical Field Comes to the Aid of Programming
Device Programmability Gains Precedence in Device Choice
Brain Imaging - Gaining Prominence in DBS
Novel Imaging Techniques Come to the Fore
New DBS Technique Promises Superior Outcomes
Lack of Large Scale Study Results Subdue Asleep DBS; for Now
Concerns Remain Afloat – Affecting Adoption
Hardware-related Infections – A Major Concern
Battery Life – A Bone of Contention for DBS
3. TARGETED INDICATIONS FOR DBS
Parkinson’s Disease – The Largest Application Market for DBS
The DBS Procedure for Parkinson’s
Limitations of DBS
A Note on Incidence and Prevalence of Parkinson’s Disease
Table 7: Parkinson's Prevalence (In Million) by Income Category, Projections for 2005, 2015, and 2030 (includes corresponding Graph/Chart)
Research Suggests Greater Benefits of DBS in Parkinson’s
Innovations in DBS to Redefine Future of Parkinson’s Treatment
Innovations Upgrading Current Devices
Novel Stimulation Patterns and Parameters
Innovation in Enhanced Stimulation
Researchers Develop New Pulse Pattern to Improve DBS for Parkinson’s
DBS – A Highly Effective Therapy for Essential Tremor
Incidence and Prevalence of Essential Tremor
DBS in Dystonia
Clinical Evidence of DBS in Dystonia: An Overview of Results from Select Clinical Studies and Meta-Analyses
Dystonia Patient Selection Criteria for DBS
DBS in OCD
DBS in Epilepsy Treatment
Disease Overview
Table 8: Epilepsy Incidence by Type (2016): Percentage Share Breakdown for Idiopathic and Symptomatic Epilepsy (includes corresponding Graph/Chart)
Table 9: Symptomatic Epilepsy Incidence by Type (2016): Percentage Share Breakdown of Congenital, Degenerative, Infective, Neoplastic, Trauma, and Vascular Epilepsy (includes corresponding Graph/Chart)
DBS in Tourette Syndrome – Research Progress So Far
Clinical Evidence of DBS in Tourette Syndrome: An Overview of Results from Select Clinical Studies and Meta-Analyses
Paucity of Effective Drugs Drives Shift in Psychiatric Disorder Treatment
Multiple Possible Targets Marr Progress of DBS in Depression Treatment
Overview of Select Studies on DBS in Depression Treatment
SCC – A Promising Target for Stimulation in Depression
Eating Disorders - A Note on Potential of DBS
DBS: A Potential Procedure to Treat Obesity
Anorexia Treatment – Where Does DBS Stand?
DBS in Dementia Treatment – Animal Studies Bode Well for Efficacy in Humans
Prospects of DBS in Chronic Pain Management
4. PRODUCT OVERVIEW
Deep Brain Stimulation – An Overview
A Brief Note on Birth and Evolution of DBS
Devices in Deep Brain Stimulation
Components of DBS System
Implantable Pulse Generator (IPG)
The Extension
Leads/Electrodes
Other Products used in DBS Procedures
Programmers
Accessories
DBS Procedure – A Brief Overview
DBS Placement and Calibration
Common Lead Targets for Select Neurological and Psychiatric Conditions in DBS
A Peek into Indications of DBS and Other Uses
DBS Complications
A Gist of Common Complications Associated with DBS
5. RECENT INDUSTRY ACTIVITY
Boston Scientific Earns CE Mark for Vercise Gevia DBS System
Medtronic SureTune(TM)3 Receives CE Mark for DBS Therapy
Medtronic SureTune(TM)3 Earns Health Canada Licence for DBS
Aleva Neurotherapeutics Plans to Obtain CE Mark for directSTIM™ Directional DBS System
St. Jude Medical Announces US FDA Approval & First Implant of DBS and Directional Lead
Medtronic's StealthStation Cranial Software gets FDA Clearance
Medtronic SureTune2(TM) Secures CE Mark for DBS Therapy
St Jude Medical Introduces the Infinity DBS System and Directional Lead
Medtronic DBS Therapy Receives FDA Approval
Abbott Takes Over St. Jude Medical
Aleva Neurotherapeutics Inks Strategic Partnership with Greatbatch
Medtronic Deep Brain Stimulation Receives FDA Approval
FDA Approves Activa Portfolio of DBS Neurostimulators for Full-Body MRI
Boston Scientific Receives CE Mark for Vercise DBS System for Treating Tremor
St. Jude Medical Secures US FDA Approval for Brio Neurostimulation System
Medtronic Obtains EU Clearance for Full-Body MR Conditional DBS Systems
6. FOCUS ON SELECT PLAYERS
Abbott Laboratories (USA)
Aleva Neurotherapeutics SA (Switzerland)
Boston Scientific Corp. (USA)
Deep Brain Innovations, LLC (USA)
Medtronic Plc. (Ireland)
Beijing Pins Medical Co., Ltd. (China)
SceneRay Corporation Limited (China)
7. GLOBAL MARKET PERSPECTIVE
Table 10: World Recent Past, Current & Future Analysis for Deep Brain Stimulation Devices by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2016 through 2024 (includes corresponding Graph/Chart)
Table 11: World Historic Review for Deep Brain Stimulation Devices by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2011 through 2015 (includes corresponding Graph/Chart)
Table 12: World 14-Year Perspective for Deep Brain Stimulation Devices by Geographic Region - Percentage Breakdown of Value Sales for US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America and Rest of World Markets for Years 2011, 2017 & 2024 (includes corresponding Graph/Chart)
III. MARKET
1. THE UNITED STATES
A. Market Analysis
United States Leads the Global DBS Market
Table 13: Prevalence of Major Neurological Disorders in the US (includes corresponding Graph/Chart)
Medtronic Leads the US Market, Faces Competition from Abbott and Boston
Table 14: The US DBS Market by Leading Player (2016 & 2017E): Market Share Breakdown of Revenues for Medtronic, Boston Scientific, and Abbott (includes corresponding Graph/Chart)
Factors Hampering the Uptake of DBS, and Manufacturers’ Initiatives
Use of DBS in Early-Stage PD to Offer Improved Results
Aging Population: A Key Growth Driver
Table 15: Aging Population in the US (2015 & 2030): 60 Years and Above Population (in Thousands) and Percentage of Population (includes corresponding Graph/Chart)
Table 16: North American Elderly Population by Age Group (1975-2050) (includes corresponding Graph/Chart)
DBS Reimbursement Scenario in the US
Medicare HCPCS II Device Codes for DBS
Table 17: CPT® Procedure Codes and Facility Payment for DBS for the period-January 1st 2017 to December 31st 2017
Table 18: CPT® Procedure Codes and Hospital Outpatient Payment for the period January 1st 2017 to December 31st 2017
Table 19: CPT® Procedure Codes and Hospital Inpatient Payment for the Period January 1st 2017 to December 31st 2017
Table 20: CPT® Procedure Codes and Ambulatory Surgical Center (ASC) Payment for the period January 1st 2017 to December 31st 2017
Product Launches
Strategic Corporate Developments
Select Key Players
B. Market Analytics
Table 21: The US Recent Past, Current & Future Analysis for Deep Brain Stimulation Devices Market - Analyzed with Annual Sales Figures in US$ Thousand for Years 2016 through 2024 (includes corresponding Graph/Chart)
Table 22: The US Historic Review for Deep Brain Stimulation Devices Market - Analyzed with Annual Sales Figures in US$ Thousand for Years 2011 through 2015 (includes corresponding Graph/Chart)
2. CANADA
A. Market Analysis
Product Launch
B. Market Analytics
Table 23: Canadian Recent Past, Current & Future Analysis for Deep Brain Stimulation Devices Market - Analyzed with Annual Sales Figures in US$ Thousand for Years 2016 through 2024 (includes corresponding Graph/Chart)
Table 24: Canadian Historic Review for Deep Brain Stimulation Devices Market - Analyzed with Annual Sales Figures in US$ Thousand for Years 2011 through 2015 (includes corresponding Graph/Chart)
3. JAPAN
A. Market Analysis
Graying Population Spurs Growth of CNS Therapeutics
Table 25: Japanese Elderly (65+ Years) Population: 2000-2020 (includes corresponding Graph/Chart)
DBS Approvals in Japan
List of Approved and Investigational Indications for Deep Brain Stimulation
B. Market Analytics
Table 26: Japanese Recent Past, Current & Future Analysis for Deep Brain Stimulation Devices Market - Analyzed with Annual Sales Figures in US$ Thousand for Years 2016 through 2024 (includes corresponding Graph/Chart)
Table 27: Japanese Historic Review for Deep Brain Stimulation Devices Market - Analyzed with Annual Sales Figures in US$ Thousand for Years 2011 through 2015 (includes corresponding Graph/Chart)
4. EUROPE
A. Market Analysis
Current & Future Analysis
Table 28: European Country-wise Statistics of 65+ Population as % of Total Population: As on January 1, 2015 (includes corresponding Graph/Chart)
Product Approvals/Launches
Select Key Players
B. Market Analytics
Table 29: European Recent Past, Current & Future Analysis for Deep Brain Stimulation Devices by Geographic Region - France, Germany, Italy, UK, Spain, Russia and Rest of Europe Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2016 through 2024 (includes corresponding Graph/Chart)
Table 30: European Historic Review for Deep Brain Stimulation Devices by Geographic Region - France, Germany, Italy, UK, Spain, Russia and Rest of Europe Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2011 through 2015 (includes corresponding Graph/Chart)
Table 31: European 14-Year Perspective for Deep Brain Stimulation Devices by Geographic Region - Percentage Breakdown of Value Sales for France, Germany, Italy, UK, Spain, Russia and Rest of Europe Markets for Years 2011, 2017 & 2024 (includes corresponding Graph/Chart)
5. ASIA-PACIFIC
A. Market Analysis
Current & Future Analysis
China and India Offer Significant Growth Opportunities
Table 32: China and India Lead Global Population (2015): Table Depicting China and India’s Huge Population Vis-a-vis Other Countries’ Population (in Millions) by Age Group (includes corresponding Graph/Chart)
Select Key Players
B. Market Analytics
Table 33: Asia-Pacific Recent Past, Current & Future Analysis for Deep Brain Stimulation Devices by Geographic Region - China, India and Rest of Asia-Pacific Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2016 through 2024 (includes corresponding Graph/Chart)
Table 34: Asia-Pacific Historic Review for Deep Brain Stimulation Devices by Geographic Region - China, India and Rest of Asia-Pacific Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2011 through 2015 (includes corresponding Graph/Chart)
Table 35: Asia-Pacific 14-Year Perspective for Deep Brain Stimulation Devices by Geographic Region - Percentage Breakdown of Value Sales for China, India and Rest of Asia-Pacific Markets for Years 2011, 2017 & 2024 (includes corresponding Graph/Chart)
5a. CHINA
A. Market Analysis
China - Fastest Growing Market for DBS
B. Market Analytics
Table 36: Chinese Recent Past, Current & Future Analysis for Deep Brain Stimulation Devices Market - Analyzed with Annual Sales Figures in US$ Thousand for Years 2016 through 2024 (includes corresponding Graph/Chart)
Table 37: Chinese Historic Review for Deep Brain Stimulation Devices Market - Analyzed with Annual Sales Figures in US$ Thousand for Years 2011 through 2015 (includes corresponding Graph/Chart)
5b. INDIA
A. Market Analysis
Indian DBS Market on the Roll
Growing Medical Tourism to Support DBS Market in India
B. Market Analytics
Table 38: Indian Recent Past, Current & Future Analysis for Deep Brain Stimulation Devices Market - Analyzed with Annual Sales Figures in US$ Thousand for Years 2016 through 2024 (includes corresponding Graph/Chart)
Table 39: Indian Historic Review for Deep Brain Stimulation Devices Market - Analyzed with Annual Sales Figures in US$ Thousand for Years 2011 through 2015 (includes corresponding Graph/Chart)
5c. REST OF ASIA-PACIFIC
A. Market Analysis
Current & Future Analysis
Overview of the Australian DBS Market
Competitive Landscape
B. Market Analytics
Table 40: Rest of Asia-Pacific Recent Past, Current & Future Analysis for Deep Brain Stimulation Devices Market - Analyzed with Annual Sales Figures in US$ Thousand for Years 2016 through 2024 (includes corresponding Graph/Chart)
Table 41: Rest of Asia-Pacific Historic Review for Deep Brain Stimulation Devices Market - Analyzed with Annual Sales Figures in US$ Thousand for Years 2011 through 2015 (includes corresponding Graph/Chart)
6. LATIN AMERICA
Market Analysis
Table 42: Latin American Recent Past, Current & Future Analysis for Deep Brain Stimulation Devices by Geographic Region - Brazil and Rest of Latin American Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2016 through 2024 (includes corresponding Graph/Chart)
Table 43: Latin American Historic Review for Deep Brain Stimulation Devices by Geographic Region - Brazil and Rest of Latin American Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2011 through 2015 (includes corresponding Graph/Chart)
Table 44: Latin American 14-Year Perspective for Deep Brain Stimulation Devices by Geographic Region - Percentage Breakdown of Value Sales for Brazil and Rest of Latin American Markets for Years 2011, 2017 & 2024 (includes corresponding Graph/Chart)
7. REST OF WORLD
Market Analysis
Table 45: Rest of World Recent Past, Current & Future Analysis for Deep Brain Stimulation Devices Market - Analyzed with Annual Sales Figures in US$ Thousand for Years 2016 through 2024 (includes corresponding Graph/Chart)
Table 46: Rest of World Historic Review for Deep Brain Stimulation Devices Market - Analyzed with Annual Sales Figures in US$ Thousand for Years 2011 through 2015 (includes corresponding Graph/Chart)
IV. COMPETITIVE LANDSCAPE Total Companies Profiled: 21 (including Divisions/Subsidiaries - 22)
The United States (11)
Canada (1)
Europe (7)
- France (1)
- Germany (3)
- The United Kingdom (1)
- Rest of Europe (2)
Asia-Pacific (Excluding Japan) (3)

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