Type 2 Diabetes Mellitus Therapeutics in Asia-Pacific Markets to 2021 - Increasing Usage of Newer Therapies and Expanding Treatment Population to Encourage Robust Growth
Diabetes mellitus is a group of metabolic diseases characterized by chronic hyperglycemia - high blood glucose levels - that results from defects in insulin secretion, insulin action, or a combination of these. This chronic hyperglycemia is associated with long-term damage, dysfunction and failure of multiple organs including the eyes, kidneys, nerves, heart and blood vessels. The vast majority of diabetes mellitus patients can be classified as having either Type 1 Diabetes Mellitus (T1DM) or Type 2 Diabetes Mellitus (T2DM). Approximately 85-95% of all diabetics have T2DM.
T2DM treatment has been revolutionized in the past decade, especially with the increased use of new therapies. The marketed products landscape comprises a wide range of treatment options, including biguanide (metformin), sulfonylureas, thiazolidinediones, GLP-1 receptor agonist, DPP-4 inhibitor, SGLT-2 inhibitor, and insulin therapies. Nevertheless, significant unmet need remains for products that can offer better glycemic control as well as the prevention and cure of diabetic complications, such as diabetic nephropathy, retinopathy, and cardiovascular disease.
The current T2DM in the Asia-Pacific (APAC) market contains novel products, including Jardiance - a SGLT-2 inhibitor; Victoza - a GLP-1 receptor agonist; and Galvus - a DPP-4 inhibitor.
Asia-Pacific Type 2 Diabetes Mellitus Treatment Market Will Exceed $10 Billion by 2021, says GBI Research
The treatment market for Type 2 Diabetes Mellitus (T2DM) in the Asia-Pacific (APAC) region will increase from a little under $6.1 billion in 2014 to just over $10 billion by 2021, at a Compound Annual Growth Rate (CAGR) of 7.7%, according to business intelligence provider GBI Research.
The company’s latest report* states that this substantial growth, which will occur across the countries of China, India, Japan and Australia, will be driven by the rapidly expanding prevalence population resulting from increasingly aging populations and sedentary lifestyles. Higher diagnosis and treatment rates, due to rising disease awareness among the public, will also play a role.
Aswini Nath, Senior Analyst for GBI Research, says: “T2DM is becoming an increasingly common problem in APAC regions as they become more industrialized and diets become more Westernized. In line with this, there is a very large and innovative pipeline, suggesting a strong potential for unmet needs to be addressed in coming years.
“The late-stage pipeline contains a high proportion of products from established drug classes, with improved dosing regimens and administration routes in comparison to currently marketed products. This suggests that unmet needs relating to patient convenience and ease of use will be addressed most significantly over the forecast period.”
GBI Research also states that the recently approved drug classes, GLP-1 receptor agonists, DPP-4 inhibitors, and SGLT-2 inhibitors, are expected to increase their market share by 2021.
Nath continues: “In comparison to many previously marketed therapies, the new drug classes provide beneficial effects such as improved weight control and lowered hypoglycemia risk. Furthermore, a recent study also identified cardiovascular risk reduction with Jardiance, an SGLT-2 inhibitor.
“These treatments have already achieved strong market uptake, which is expected to increase over the forecast period. The recently launched products in the APAC region that are expected to contribute most significantly to market growth include Forxiga, Invokana, and Jardiance; DPP-4 inhibitors - Zafatek, and Tenglyn/Ziten.”
*Type 2 Diabetes Mellitus Therapeutics in Asia-Pacific Markets to 2021 - Increasing Usage of Newer Therapies and Expanding Treatment Population to Encourage Robust Growth
This report provides analysis of the Type 2 Diabetes Mellitus (T2DM) treatment arena in the Asia-Pacific (APAC) countries of China, India, Japan, and Australia. It includes annualized market data from 2014 and forecast to 2021, highlights current unmet needs, and discusses the current clinical and commercial landscape of the APAC T2DM therapeutics space.
This report was built using data and information sourced from proprietary databases, primary and secondary research, and in-house analysis conducted by GBI Research’s team of industry experts.
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