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Swine and Avian Influenza Drug Development Pipeline Review, 2017

Swine and Avian Influenza Drug Development Pipeline Review, 2017

Summary

H5N1 is a type of influenza virus that causes a highly infectious, severe respiratory disease in birds called avian influenza. This virus can spread to humans. There are a total of 63 products in development for this indication, by 47 companies and six academic institutions. Key companies operating in this pipeline space include Gemmus Pharma, Aphios, Fides Pharma, Inovio Pharmaceuticals, Microbiotix, NanoViricides, Shionogi, the University of Wisconsin Madison and Tria Bioscience.

H1N1 Infection also called as swine flu is a new kind of flu in humans. It's caused by the contagious H1N1 influenza virus. There are a total of 99 products in development for this indication, by 67 companies and 14 academic institutions. Key companies operating in this pipeline space include Johnson & Johnson, and the University of Sherbrooke.

In both types of influenza, the most common molecular target being studied is hemagglutinin, by a considerable margin. However, a number of both human and viral proteins are also under active development.

This report provides an overview of the Swine and Avian Influenza pipeline landscape. The report provides comprehensive information on the therapeutics under development and key players involved in therapeutic development for influenza A virus, subtypes H5N1 and H1N1, and features dormant and discontinued projects. Symptoms of influenza include fever and cough, fatigue, acute respiratory distress, shortness of breath, abdominal pain and diarrhea.

Scope

  • Which companies are the most active within each pipeline?
  • Which pharmaceutical approaches are the most prominent at each stage of the pipeline and within each indication?
  • To what extent do universities and institutions play a role within this pipeline, compared to pharmaceutical companies?
  • What are the most important R&D milestones and data publications to have happened in this disease area?
Reasons to buy
  • Understand the overall pipeline, with an at-a-glance overview of all products in therapeutic development for each indication
  • Assess the products in development in granular detail, with an up-to-date overview of each individual pipeline program in each indication, and a comprehensive picture of recent updates and milestones for each
  • Analyze the companies, institutions and universities currently operating in the pipeline, and the products being fielded by each of these
  • Understand the composition of the pipeline in terms of molecule type, molecular target, mechanism of action and route of administration


  • GBI Research Report Guidance
  • Executive Summary
  • Introduction
    • Swine and Avian Influenza Report Coverage
    • Influenza A Virus, H5N1 Subtype Infections - Overview
    • Influenza A Virus, H1N1 Subtype Infections - Overview
  • Therapeutics Development
    • Influenza A Virus, H5N1 Subtype Infections
      • Pipeline Overview
        • Table figure 1: Number of Products under Development for Influenza A Virus, H5N1 Subtype Infections
        • Table Number of Products under Development for Influenza A Virus, H5N1 Subtype Infections
      • Pipeline by Companies
        • Table figure 2: Number of Products under Development by Companies Influenza A Virus, H5N1 Subtype Infections
        • Table Number of Products under Development by Companies Influenza A Virus, H5N1 Subtype Infections
      • Pipeline by Universities/Institutes
        • Table figure 3: Number of Products under Development by Universities/Institutes Influenza A Virus, H5N1 Subtype Infections
        • Table Number of Products under Development by Universities/Institutes Influenza A Virus, H5N1 Subtype Infections
      • Products under Development by Companies
        • Table Products under Development by Companies Influenza A Virus, H5N1 Subtype Infections
      • Products under Development by Universities/Institutes
        • Table Products under Development by Universities/Institutes Influenza A Virus, H5N1 Subtype Infections
    • Influenza A Virus, H1N1 Subtype Infections
      • Pipeline Overview
        • Table figure 4: Number of Products under Development for Influenza A Virus, H1N1 Subtype Infections
        • Table Number of Products under Development for Influenza A Virus, H1N1 Subtype Infections
      • Pipeline by Companies
        • Table figure 5: Number of Products under Development by Companies Influenza A Virus, H1N1 Subtype Infections
        • Table Number of Products under Development by Companies Influenza A Virus, H1N1 Subtype Infections
      • Pipeline by Universities/Institutes
        • Table figure 6: Number of Products under Development by Universities/Institutes Influenza A Virus, H1N1 Subtype Infections
        • Table Number of Products under Development by Universities/Institutes Influenza A Virus, H1N1 Subtype Infections
      • Products under Development by Companies
        • Table Products under Development by Companies Influenza A Virus, H1N1 Subtype Infections
      • Products under Development by Universities/Institutes
        • Table Products under Development by Universities/Institutes Influenza A Virus, H1N1 Subtype Infections
  • Therapeutics Assessment
    • Influenza A Virus, H5N1 Subtype Infections
      • Assessment by Target
        • Table figure 7: Number of Products by Top 10 Targets Influenza A Virus, H5N1 Subtype Infections
        • Table figure 8: Number of Products by Stage and Top 10 Targets Influenza A Virus, H5N1 Subtype Infections
        • Table Number of Products by Stage and Target Influenza A Virus, H5N1 Subtype Infections
      • Assessment by Mechanism of Action
        • Table figure 9: Number of Products by Top 10 Mechanism of Actions Influenza A Virus, H5N1 Subtype Infections
        • Table figure 10: Number of Products by Stage and Top 10 Mechanism of Actions Influenza A Virus, H5N1 Subtype Infections
        • Table Number of Products by Stage and Mechanism of Action Influenza A Virus, H5N1 Subtype Infections
      • Assessment by Route of Administration
        • Table figure 11: Number of Products by Top 10 Routes of Administration Influenza A Virus, H5N1 Subtype Infections
        • Table figure 12: Number of Products by Stage and Top 10 Routes of Administration Influenza A Virus, H5N1 Subtype Infections
        • Table Number of Products by Stage and Route of Administration Influenza A Virus, H5N1 Subtype Infections
      • Assessment by Molecule Type
        • Table figure 13: Number of Products by Top 10 Molecule Types Influenza A Virus, H5N1 Subtype Infections
        • Table figure 14: Number of Products by Stage and Top 10 Molecule Types Influenza A Virus, H5N1 Subtype Infections
        • Table Number of Products by Stage and Molecule Type Influenza A Virus, H5N1 Subtype Infections
    • Influenza A Virus, H1N1 Subtype Infections
      • Assessment by Target
        • Table figure 15: Number of Products by Top 10 Targets Influenza A Virus, H1N1 Subtype Infections
        • Table figure 16: Number of Products by Stage and Top 10 Targets Influenza A Virus, H1N1 Subtype Infections
        • Table Number of Products by Stage and Target Influenza A Virus, H1N1 Subtype Infections
      • Assessment by Mechanism of Action
        • Table figure 17: Number of Products by Top 10 Mechanism of Actions Influenza A Virus, H1N1 Subtype Infections
        • Table figure 18: Number of Products by Stage and Top 10 Mechanism of Actions Influenza A Virus, H1N1 Subtype Infections
        • Table Number of Products by Stage and Mechanism of Action Influenza A Virus, H1N1 Subtype Infections
      • Assessment by Route of Administration
        • Table figure 19: Number of Products by Top 10 Routes of Administration Influenza A Virus, H1N1 Subtype Infections
        • Table figure 20: Number of Products by Stage and Top 10 Routes of Administration Influenza A Virus, H1N1 Subtype Infections
        • Table Number of Products by Stage and Route of Administration Influenza A Virus, H1N1 Subtype Infections
      • Assessment by Molecule Type
        • Table figure 21: Number of Products by Top 10 Molecule Types Influenza A Virus, H1N1 Subtype Infections
        • Table figure 22: Number of Products by Stage and Top 10 Molecule Types Influenza A Virus, H1N1 Subtype Infections
        • Table Number of Products by Stage and Molecule Type Influenza A Virus, H1N1 Subtype Infections
  • Companies Involved in Therapeutics Development
    • Influenza A Virus, H5N1 Subtype Infections
      • Akshaya Bio Inc
        • Table Influenza A Virus, H5N1 Subtype Infections - Pipeline by Akshaya Bio Inc
      • Altimmune Inc
        • Table Influenza A Virus, H5N1 Subtype Infections - Pipeline by Altimmune Inc
      • Antigen Express Inc
        • Table Influenza A Virus, H5N1 Subtype Infections - Pipeline by Antigen Express Inc
      • Aphios Corp
        • Table Influenza A Virus, H5N1 Subtype Infections - Pipeline by Aphios Corp
      • BiondVax Pharmaceuticals Ltd
        • Table Influenza A Virus, H5N1 Subtype Infections - Pipeline by BiondVax Pharmaceuticals Ltd
      • CEL-SCI Corp
        • Table Influenza A Virus, H5N1 Subtype Infections - Pipeline by CEL-SCI Corp
      • Cocrystal Pharma Inc
        • Table Influenza A Virus, H5N1 Subtype Infections - Pipeline by Cocrystal Pharma Inc
      • Curevac AG
        • Table Influenza A Virus, H5N1 Subtype Infections - Pipeline by Curevac AG
      • Gemmus Pharma Inc
        • Table Influenza A Virus, H5N1 Subtype Infections - Pipeline by Gemmus Pharma Inc
      • GlaxoSmithKline Plc
        • Table Influenza A Virus, H5N1 Subtype Infections - Pipeline by GlaxoSmithKline Plc
      • Hemispherx Biopharma Inc
        • Table Influenza A Virus, H5N1 Subtype Infections - Pipeline by Hemispherx Biopharma Inc
      • iBio Inc
        • Table Influenza A Virus, H5N1 Subtype Infections - Pipeline by iBio Inc
      • Inovio Pharmaceuticals Inc
        • Table Influenza A Virus, H5N1 Subtype Infections - Pipeline by Inovio Pharmaceuticals Inc
      • Johnson & Johnson
        • Table Influenza A Virus, H5N1 Subtype Infections - Pipeline by Johnson & Johnson
      • Kineta Inc
        • Table Influenza A Virus, H5N1 Subtype Infections - Pipeline by Kineta Inc
      • Lakewood-Amedex Inc
        • Table Influenza A Virus, H5N1 Subtype Infections - Pipeline by Lakewood-Amedex Inc
      • Medicago Inc
        • Table Influenza A Virus, H5N1 Subtype Infections - Pipeline by Medicago Inc
      • Medigen Vaccine Biologics Corp
        • Table Influenza A Virus, H5N1 Subtype Infections - Pipeline by Medigen Vaccine Biologics Corp
      • Microbiotix Inc
        • Table Influenza A Virus, H5N1 Subtype Infections - Pipeline by Microbiotix Inc
      • NanoBio Corp
        • Table Influenza A Virus, H5N1 Subtype Infections - Pipeline by NanoBio Corp
      • Nanotherapeutics Inc
        • Table Influenza A Virus, H5N1 Subtype Infections - Pipeline by Nanotherapeutics Inc
      • NanoViricides Inc
        • Table Influenza A Virus, H5N1 Subtype Infections - Pipeline by NanoViricides Inc
      • OPKO Health Inc
        • Table Influenza A Virus, H5N1 Subtype Infections - Pipeline by OPKO Health Inc
      • PaxVax Inc
        • Table Influenza A Virus, H5N1 Subtype Infections - Pipeline by PaxVax Inc
      • PeptiDream Inc
        • Table Influenza A Virus, H5N1 Subtype Infections - Pipeline by PeptiDream Inc
      • Shionogi & Co Ltd
        • Table Influenza A Virus, H5N1 Subtype Infections - Pipeline by Shionogi & Co Ltd
      • Takeda Pharmaceutical Company Ltd
        • Table Influenza A Virus, H5N1 Subtype Infections - Pipeline by Takeda Pharmaceutical Company
      • TechnoVax Inc
        • Table Influenza A Virus, H5N1 Subtype Infections - Pipeline by TechnoVax Inc
      • Vaxart Inc
        • Table Influenza A Virus, H5N1 Subtype Infections - Pipeline by Vaxart Inc
      • Vaxine Pty Ltd
        • Table Influenza A Virus, H5N1 Subtype Infections - Pipeline by Vaxine Pty Ltd
      • Visterra Inc
        • Table Influenza A Virus, H5N1 Subtype Infections - Pipeline by Visterra Inc
    • Influenza A Virus, H1N1 Subtype Infections
      • AbbVie Inc
        • Table Influenza A Virus, H1N1 Subtype Infections - Pipeline by AbbVie Inc
      • Adimmune Corp
        • Table Influenza A Virus, H1N1 Subtype Infections - Pipeline by Adimmune Corp
      • Akshaya Bio Inc
        • Table Influenza A Virus, H1N1 Subtype Infections - Pipeline by Akshaya Bio Inc
      • Altimmune Inc
        • Table Influenza A Virus, H1N1 Subtype Infections - Pipeline by Altimmune Inc
      • Antigen Express Inc
        • Table Influenza A Virus, H1N1 Subtype Infections - Pipeline by Antigen Express Inc
      • Beijing Minhai Biotechnology Co Ltd
        • Table Influenza A Virus, H1N1 Subtype Infections - Pipeline by Beijing Minhai Biotechnology Co Ltd
      • BioCryst Pharmaceuticals Inc
        • Table Influenza A Virus, H1N1 Subtype Infections - Pipeline by BioCryst Pharmaceuticals Inc
      • Cadila Healthcare Ltd
        • Table Influenza A Virus, H1N1 Subtype Infections - Pipeline by Cadila Healthcare Ltd
      • CEL-SCI Corp
        • Table Influenza A Virus, H1N1 Subtype Infections - Pipeline by CEL-SCI Corp
      • Cilian AG
        • Table Influenza A Virus, H1N1 Subtype Infections - Pipeline by Cilian AG
      • Cocrystal Pharma Inc
        • Table Influenza A Virus, H1N1 Subtype Infections - Pipeline by Cocrystal Pharma Inc
      • ContraFect Corp
        • Table Influenza A Virus, H1N1 Subtype Infections - Pipeline by ContraFect Corp
      • Curevac AG
        • Table Influenza A Virus, H1N1 Subtype Infections - Pipeline by Curevac AG
      • EpiVax Inc
        • Table Influenza A Virus, H1N1 Subtype Infections - Pipeline by EpiVax Inc
      • Etubics Corp
        • Table Influenza A Virus, H1N1 Subtype Infections - Pipeline by Etubics Corp
      • Gemmus Pharma Inc
        • Table Influenza A Virus, H1N1 Subtype Infections - Pipeline by Gemmus Pharma Inc
      • Genentech Inc
        • Table Influenza A Virus, H1N1 Subtype Infections - Pipeline by Genentech Inc
      • iBio Inc
        • Table Influenza A Virus, H1N1 Subtype Infections - Pipeline by iBio Inc
      • Inovio Pharmaceuticals Inc
        • Table Influenza A Virus, H1N1 Subtype Infections - Pipeline by Inovio Pharmaceuticals Inc
      • Jiangsu Kanion Pharmaceutical Co Ltd
        • Table Influenza A Virus, H1N1 Subtype Infections - Pipeline by Jiangsu Kanion Pharmaceutical Co Ltd
      • Johnson & Johnson
        • Table Influenza A Virus, H1N1 Subtype Infections - Pipeline by Johnson & Johnson
      • Kineta Inc
        • Table Influenza A Virus, H1N1 Subtype Infections - Pipeline by Kineta Inc
      • Kyowa Hakko Kirin Co Ltd
        • Table Influenza A Virus, H1N1 Subtype Infections - Pipeline by Kyowa Hakko Kirin Co Ltd
      • Lakewood-Amedex Inc
        • Table Influenza A Virus, H1N1 Subtype Infections - Pipeline by Lakewood-Amedex Inc
      • Medicago Inc
        • Table Influenza A Virus, H1N1 Subtype Infections - Pipeline by Medicago Inc
      • MedImmune LLC
        • Table Influenza A Virus, H1N1 Subtype Infections - Pipeline by MedImmune LLC
      • Microbiotix Inc
        • Table Influenza A Virus, H1N1 Subtype Infections - Pipeline by Microbiotix Inc
      • Mucosis BV
        • Table Influenza A Virus, H1N1 Subtype Infections - Pipeline by Mucosis BV
      • NanoViricides Inc
        • Table Influenza A Virus, H1N1 Subtype Infections - Pipeline by NanoViricides Inc
      • NewLink Genetics Corp
        • Table Influenza A Virus, H1N1 Subtype Infections - Pipeline by NewLink Genetics Corp
      • Novavax Inc
        • Table Influenza A Virus, H1N1 Subtype Infections - Pipeline by Novavax Inc
      • OPKO Health Inc
        • Table Influenza A Virus, H1N1 Subtype Infections - Pipeline by OPKO Health Inc
      • PeptiDream Inc
        • Table Influenza A Virus, H1N1 Subtype Infections - Pipeline by PeptiDream Inc
      • Recce Ltd
        • Table Influenza A Virus, H1N1 Subtype Infections - Pipeline by Recce Ltd
      • Sanofi
        • Table Influenza A Virus, H1N1 Subtype Infections - Pipeline by Sanofi
      • Sanofi Pasteur SA
        • Table Influenza A Virus, H1N1 Subtype Infections - Pipeline by Sanofi Pasteur SA
      • Sarepta Therapeutics Inc
        • Table Influenza A Virus, H1N1 Subtype Infections - Pipeline by Sarepta Therapeutics Inc
      • SK Chemicals Co Ltd
        • Table Influenza A Virus, H1N1 Subtype Infections - Pipeline by SK Chemicals Co Ltd
      • Takeda Pharmaceutical Company Ltd
        • Table Influenza A Virus, H1N1 Subtype Infections - Pipeline by Takeda Pharmaceutical Company Ltd
      • TechnoVax Inc
        • Table Influenza A Virus, H1N1 Subtype Infections - Pipeline by TechnoVax Inc
      • Touchlight Genetics Ltd
        • Table Influenza A Virus, H1N1 Subtype Infections - Pipeline by Touchlight Genetics Ltd
      • Vaccibody AS
        • Table Influenza A Virus, H1N1 Subtype Infections - Pipeline by Vaccibody AS
      • Vaxart Inc
        • Table Influenza A Virus, H1N1 Subtype Infections - Pipeline by Vaxart Inc
      • Vironova AB
        • Table Influenza A Virus, H1N1 Subtype Infections - Pipeline by Vironova AB
      • Visterra Inc
        • Table Influenza A Virus, H1N1 Subtype Infections - Pipeline by Visterra Inc
  • Dormant Projects
    • Influenza A Virus, H5N1 Subtype Infections
      • Table Influenza A Virus, H5N1 Subtype Infections - Dormant Projects
    • Influenza A Virus, H1N1 Subtype Infections
      • Table Influenza A Virus, H1N1 Subtype Infections - Dormant Projects
  • Discontinued Products
    • Influenza A Virus, H5N1 Subtype Infections
      • Table Influenza A Virus, H5N1 Subtype Infections - Discontinued Products
    • Influenza A Virus, H1N1 Subtype Infections
      • Table Influenza A Virus, H1N1 Subtype Infections - Discontinued Products
  • Product Development Milestones
    • Influenza A Virus, H5N1 Subtype Infections
      • Featured News & Press Releases
    • Influenza A Virus, H1N1 Subtype Infections
      • Featured News & Press Releases
  • Appendix
    • Methodology
    • Coverage
    • Secondary Research
    • Primary Research
    • Expert Panel Validation
    • Contact Us
    • Disclaimer

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