Global Non-Hematological Cancers Market to 2021 - Strong growth driven by increased uptake of low toxicity targeted treatments and versatile biologics
In 2012, there were 32.6 million people living with any type of cancer within five years of diagnosis, non-hematological cancers are thought to account for 94% of global cancer prevalence. The key cancer indications of this report, namely breast, colorectal, lung and prostate cancer, constitute approximately 51% of global cancer prevalence.
The risk of cancer increases greatly in patients over the age of 65. As populations are projected to increase, with aging and increasing incidence of obesity, the prevalence of cancer as a genetic disease is only anticipated to increase, thereby acting as a driver for revenue growth. Typically, chemotherapy has curative or palliative uses depending on whether the patient’s tumors are resectable or unresectable, respectively; however, use of chemotherapies is often reliant on performance status, which is lacking in many cancer patients.
There has been a shift towards developing targeted therapies, which by their nature have less toxicity associated with their use and as a result can be administered to greater numbers of cancer patients, who are commonly elderly and have co-morbidities, therefore increasing the overall survival of this group and the number of treatment cycles they may receive.
Global revenues for the non-hematological cancer market are forecast to grow at a Compound Annual Growth Rate (CAGR) of 9.86%, from $73 billion in 2014 to $141 billion in 2021
Global Non-Hematological Cancers Market Will Almost Double to $141 Billion by 2021, says GBI Research
The global treatment market for non-hematological cancers, which includes breast, colorectal, lung and prostate cancers, among others, will almost double from $72.9 billion in 2014 to $140.8 billion in 2021, at a compound annual growth rate (CAGR) of 9.9%, according to business intelligence provider GBI Research.
The company’s latest report* states that this robust growth will occur in spite of the patent expiries of a number of very commercially successful products, including Avastin, Erbitux and Herceptin. Avastin will see its first expiry in the EU in 2018, with the two others having already experienced EU expiries in 2014.
Adam Bradbury, Associate Analyst for GBI Research, explains: “These drugs are all monoclonal Antibodies (mAbs), and are therefore expected to be less susceptible to market share and price erosion following patent expiry, due to practical and regulatory barriers to entry for biosimilars. In this way, these expirations will not pose too strong a barrier to growth.”
Market drivers will include the increasing prevalence of cancer globally, and the introduction of more targeted treatments, which will improve the overall survival of poor-performance-status patients and enable more rounds of chemotherapy to be administered.
There are 2,954 non-hematological oncology products in active development, 171 of which are in Phase III development or Pre-registration, according to GBI Research.
Bradbury explains: “Although none of the products in the late-stage pipeline are expected to reach the same levels of success as the highest revenue-generating drugs currently in the market, due to the competitiveness of the landscape, there are a number of candidates that are expected to achieve strong sales during the forecast period. These include AZD-4736 and neratinib, which are both forecast to generate blockbuster revenues by 2021.
“A range of companies are actively involved in the development or marketing of these new oncology products, including most of the top 20 pharmaceutical companies, smaller publicly traded companies and privately-held enterprises. In particular, Bristol-Myers Squibb, Johnson & Johnson, Pfizer, and Novartis, are anticipated to maintain their strong market shares throughout the forecast period.
“While Roche’s market share within non-blood cancers is anticipated to decrease, partly due to the approaching patent expiries of Avastin and Tarceva, Roche is still expected to maintain the highest market share for non-hematological cancer treatment of any company throughout the forecast period.”
*Global Non-Hematological Cancers Market to 2021 - Strong growth driven by increased uptake of low toxicity targeted treatments and versatile biologics
This report provides analysis of the global non-hematological cancers treatment space, specifically breast, colorectal, lung and prostate cancer. It features annualized market data from 2014 and forecast to 2021, as well as details on the current clinical and commercial landscape.
This report was built using data and information sourced from proprietary databases, primary and secondary research, and in-house analysis conducted by GBI Research’s team of industry experts.
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