2016 Global Survey on Clinical Next-Generation Sequencing

2016 Global Survey on Clinical Next-Generation Sequencing

The primary goal of this research is to analyze the current and future adoption plans of Next-Generation Sequencing (NGS) for clinical applications. The survey seeks to collect the following key information:

Outsourcing needs and clinical NGS service providers
Current and future interest areas of clinical NGS
Genetic elements of interest
Purchase patterns for instruments and reagents
Predominantly used clinical methods (e.g., chip sequencing, whole exome)
Perspectives of NGS used as complement or replacement for current methods
Platforms used for NGS clinical data interpretation
Predominantly cited instruments for clinical use
Familiarity with clinical NGS service providers
Factors promoting adoption
Factors limiting adoption
Best practices from labs—direct quotes from lab managers

Research Methodology
Lab managers of clinical labs were invited to participate in an online survey during August–November 2016. To qualify for survey participation, respondents had to be working in a private or public laboratory, clinical research institution, reference laboratory, academic medical center facility, hospital lab, or diagnostic company that employs NGS for clinical use. Respondents had to be constant users of this technology, belong to the scientific community, and be in a position to authorize purchases. Over 184 respondents qualified for the survey including C-level officers, lab managers, directors, physicians, post docs, and principal investigators that had a direct interference with the clinical NGS community. End users were also evaluated for their ability to authorize purchases or make product recommendations. Respondents indicated a wide range of job titles, such as lab directors, scientists, lab managers, clinicians, pathologists, and lab technicians. In total, about 82% of respondents work in the United States. Nevertheless, this study is considered global because the survey was open to respondents from all countries.

  • Executive Summary
    • Key Findings
  • Research Background, Objectives, Methodology, and Respondent Demographics
    • Research Objectives
    • Research Methodology
  • Demographics
    • Technology Usage and Outsourced Respondents
    • Respondent Demographics
  • Brand Familiarity of Clinical NGS Providers
    • Brand Perception of Top 16 Providers
  • NGS Clinical Applications
    • Current and Future Interest Areas for Clinical NGS Testing
    • Top 7 Preferred Vendors for NGS Clinical Sequencing Services
    • Areas of Pathogen Clinical Research and Methodology Used
  • NGS for Infectious Disease Testing
    • Interest in Pursuing NGS-based Infectious Disease Testing
    • Current and Future Plans in Infectious Disease Testing
    • Brand Familiarity for Infectious Disease Testing
    • Sequencing Methods Used for Testing
    • Infectious Disease Sequencing Method
    • Genetic Elements of Interest for NGS Clinical Work
    • Correlation of Genetic Elements and Clinical Area of Interest
    • Correlation of Genetic Elements and Sequencing Methods
  • Instrument and Reagent Purchase Patterns
    • Complemented or Replaced Instruments in Labs
    • Complementing Instruments/Methods
    • Instrument Usage-Current and Future Use for Clinical Applications
    • Analysis of Instruments and Clinical Applications
  • Clinical NGS Data Analysis
    • NGS Data Analysis
    • Data Analysis for Specific Infectious Disease NGS Application
    • Current and Future Usage of NGS Informatics Platforms
    • Factors Promoting Adoption of Clinical NGS
    • Factors Limiting the Adoption of Clinical NGS
    • Factors that Helped Overcome Obstacles to Implementing NGS
  • Appendix
    • Additional Sources of Information

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