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Excipients

Excipients

US demand to grow 4.3% annually through 2018
Demand for pharmaceutical excipients in the US is projected to rise 4.3 percent per year to $2.0 billion in 2018. In volume terms, demand is expected to grow 1.9 percent annually to 900 million pounds over the same period. While continued growth in pharmaceutical output will be the primary driver of increases in excipient demand, gains will accelerate as excipients play a larger role in bringing additional value to pharmaceutical products by improving properties such as the controlled release or improved absorption of active ingredients.

Preservatives, suspension agents to see strong gains
Trends in pharmaceutical output by dosage formulation will have a strong influence on excipient demand by application. Output of parenteral preparations is expected to rise at an especially strong pace through 2018, supporting demand for suspension agents and preservatives. Solvents are also projected to benefit from increased shipments of parenteral drugs, although gains in dollar terms will be limited by the continued decline in glycerin prices due to oversupply.

Oral preparations are the largest category of pharmaceutical dosage formulations; thus, oral pharmaceuticals tend to require more excipients than other types of drugs and have a significant impact on excipient demand. Shipments of oral pharmaceuticals are forecast to rise at a faster pace than seen in the 2008-2013 period, supporting accelerated gains in demand for fillers, binders, coatings, flavoring agents, capsules, and disintegrants. In addition, oral formulations such as delayed- and extended-release tablets and capsules and dissolving tablets are expected to boost their market share, further raising demand for excipients such as binders and disintegrants.

Specialty excipient blends to add value to product mix
A major development in the excipient and pharmaceutical industries is the increased dependence on specialty excipient blends. Specialty excipient blends can add value to pharmaceutical products by differentiating them from competitive products, and by optimizing the production process. These value-added excipient blends are often formulated for usage in specific manufacturing processes such as direct compression or wet granulation, and are optimized for certain performance characteristics such as delayed- or extended-release oral tablets. Product differentiation will play an increasingly important role going forward as generic pharmaceutical products increase their market share and as consumers take a more active role in choosing their drugs from among a wide range of products with the same active pharmaceutical ingredients.

Polymers to benefit from specialty blend advances
Product versatility will be a key factor impacting product mix in excipient demand going forward, especially as specialty excipient blends play an increasingly important role in pharmaceutical formulation. Polymers -- including cellulose derivatives, povidone, starch, polyethylene glycol, acrylic polymers, and natural gums -- are expected to benefit from this trend as many of these products can function in multiple applications and are easily formulated with other excipients. These favorable characteristics will serve to offset the higher prices associated with some polymers.


  • INTRODUCTION
  • EXECUTIVE SUMMARY
    • Table EXCIPIENT DEMAND BY TYPE
  • MARKET ENVIRONMENT
    • General
    • Economic Factors
      • Table MACROECONOMIC INDICATORS
    • Demographic Patterns
      • Table POPULATION & HOUSEHOLDS
    • Health Care Trends
      • National Health Expenditures
        • Table NATIONAL HEALTH EXPENDITURES
      • Medical Conditions
        • Table CHRONIC CONDITIONS BY TYPE
        • Table ACUTE CONDITIONS BY TYPE
    • Pharmaceuticals
      • Table PHARMACEUTICAL SUPPLY & DEMAND
      • Therapeutic Class
        • Table PHARMACEUTICAL SHIPMENTS BY THERAPEUTIC CLASS
      • Dosage Formulations
        • Table PHARMACEUTICAL SHIPMENTS BY DOSAGE FORMULATION
      • Distribution Classifications
        • Table PHARMACEUTICAL SHIPMENTS BY DISTRIBUTION CLASSIFICATION
      • Commercial Status
        • Table PHARMACEUTICAL SHIPMENTS BY COMMERCIAL STATUS
    • Regulatory Overview
    • Historical Market Trends
      • Table EXCIPIENT MARKET, 2003-2013
    • Pricing Trends
      • Table PHARMACEUTICAL EXCIPIENT PRICING
    • Foreign Trade
    • International Markets
  • PRODUCTS
    • General
      • Table PHARMACEUTICAL EXCIPIENT DEMAND BY PRODUCT GROUP
      • Table CHART III-1 EXCIPIENT DEMAND BY PRODUCT: VALUE & VOLUME, 2013
    • Polymers
      • Table POLYMER EXCIPIENT DEMAND BY TYPE & APPLICATION
      • Table CHART III-2 POLYMER EXCIPIENT DEMAND: VALUE & VOLUME, 2013
      • Cellulose Derivatives
        • Table CELLULOSE EXCIPIENT DEMAND BY TYPE & APPLICATION
        • Table MICROCRYSTALLINE CELLULOSE EXCIPIENT DEMAND BY APPLICATION
        • Table HYDROXYPROPYL METHYLCELLULOSE EXCIPIENT DEMAND BY APPLICATION
        • Table ETHYL CELLULOSE EXCIPIENT DEMAND BY APPLICATION
        • Table METHYL CELLULOSE EXCIPIENT DEMAND BY APPLICATION
        • Table CARBOXYMETHYLCELLULOSE EXCIPIENT DEMAND BY APPLICATION
        • Table CROSCARMELLOSE SODIUM EXCIPIENT DEMAND
        • Table OTHER CELLULOSE EXCIPIENT DEMAND BY APPLICATION
      • Povidone
        • Table POVIDONE EXCIPIENT DEMAND BY APPLICATION
      • Starch Compounds
        • Table STARCH EXCIPIENT DEMAND BY TYPE & APPLICATION
        • Table PREGELATINIZED STARCH EXCIPIENT DEMAND BY APPLICATION
        • Table SODIUM STARCH GLYCOLATE EXCIPIENT DEMAND
        • Table OTHER STARCH EXCIPIENT DEMAND BY APPLICATION
      • Polyethylene Glycol
        • Table POLYETHYLENE GLYCOL EXCIPIENT DEMAND BY APPLICATION
      • Acrylic Polymers
        • Table ACRYLIC POLYMER EXCIPIENT DEMAND BY APPLICATION
      • Other Polymers
        • Table OTHER POLYMER EXCIPIENT DEMAND BY TYPE & APPLICATION
    • Alcohols
      • Table ALCOHOL EXCIPIENT DEMAND BY TYPE & APPLICATION
      • Propylene Glycol
        • Table PROPYLENE GLYCOL EXCIPIENT DEMAND BY APPLICATION
      • Glycerin
        • Table GLYCERIN EXCIPIENT DEMAND BY APPLICATION
      • Sorbitol
        • Table SORBITOL EXCIPIENT DEMAND BY APPLICATION
      • Other Alcohols
        • Table OTHER ALCOHOL EXCIPIENT DEMAND BY TYPE & APPLICATION
    • Minerals
      • Table MINERAL EXCIPIENT DEMAND BY TYPE & APPLICATION
      • Calcium Phosphate
        • Table CALCIUM PHOSPHATE EXCIPIENT DEMAND
      • Calcium Carbonate
        • Table CALCIUM CARBONATE EXCIPIENT DEMAND
      • Clay
        • Table CLAY EXCIPIENT DEMAND BY APPLICATION
      • Mineral Hydrocarbons
        • Table MINERAL HYDROCARBON EXCIPIENT DEMAND BY APPLICATION
      • Silicon Dioxide
        • Table SILICON DIOXIDE EXCIPIENT DEMAND BY APPLICATION
      • Titanium Dioxide
        • Table TITANIUM DIOXIDE EXCIPIENT DEMAND
      • Other Minerals
        • Table OTHER MINERAL EXCIPIENT DEMAND BY APPLICATION
    • Gelatin
      • Table GELATIN EXCIPIENT DEMAND BY APPLICATION
    • Sugars
      • Table SUGAR EXCIPIENT DEMAND BY TYPE & APPLICATION
      • Lactose
        • Table LACTOSE EXCIPIENT DEMAND BY APPLICATION
      • Sucrose
        • Table SUCROSE EXCIPIENT DEMAND BY APPLICATION
      • Other Sugar Excipients
        • Table OTHER SUGAR EXCIPIENT DEMAND BY APPLICATION
    • Other Pharmaceutical Excipients
      • Table OTHER PHARMACEUTICAL EXCIPIENT DEMAND BY TYPE & APPLICATION
      • Dyes & Pigments
      • Flavors
      • Surfactants
      • Acidulants
      • Antioxidants & Antimicrobials
      • All Other Compounds
  • APPLICATIONS
    • General
      • Table PHARMACEUTICAL EXCIPIENT DEMAND BY APPLICATION
      • Table CHART IV-1 PHARMACEUTICAL EXCIPIENT DEMAND BY APPLICATION, 2013
    • Fillers & Diluents
      • Table FILLER & DILUENT EXCIPIENT DEMAND BY TYPE
    • Binders
      • Table BINDER EXCIPIENT DEMAND BY TYPE
    • Suspension & Viscosity Agents
      • Table SUSPENSION & VISCOSITY EXCIPIENT DEMAND BY TYPE
    • Coatings
      • Table COATING EXCIPIENT DEMAND BY TYPE
    • Solvents
      • Table SOLVENT EXCIPIENT DEMAND BY TYPE
    • Flavoring Agents
      • Table FLAVORING AGENT EXCIPIENT DEMAND BY TYPE
    • Capsules
      • Table CAPSULE EXCIPIENT DEMAND BY TYPE
    • Disintegrants
      • Table DISINTEGRANT EXCIPIENT DEMAND BY TYPE
    • Colorants
      • Table COLORANT EXCIPIENT DEMAND BY TYPE
    • Lubricants & Glidants
      • Table LUBRICANT & GLIDANT EXCIPIENT DEMAND BY TYPE
    • Preservatives
      • Table PRESERVATIVE EXCIPIENT DEMAND BY TYPE
    • Other Applications
      • Table OTHER APPLICATIONS FOR EXCIPIENTS BY TYPE
  • INDUSTRY STRUCTURE
    • General
      • Table US EXCIPIENT SALES BY COMPANY, 2013
    • Market Share
      • Table CHART V-1 US EXCIPIENT MARKET SHARE, 2013
    • Competitive Strategies
      • Industry Restructuring
        • Table SELECTED ACQUISITIONS & DIVESTITURES
      • Cooperative Agreements
        • Table SELECTED COOPERATIVE AGREEMENTS
      • Marketing & Distribution
      • Research & Development
      • Manufacturing
    • Company Profiles
      • Akzo Nobel NV
      • Archer-Daniels-Midland Company
      • Ashland Incorporated
      • Associated British Foods plc
      • Avantor Performance Materials Incorporated
      • BASF SE
      • Berkshire Hathaway Incorporated
      • Berwind Corporation
      • Cabot Corporation
      • Cargill Incorporated
      • Celanese Corporation
      • Croda International plc
      • Dow Chemical Company
      • DuPont (EI) de Nemours
      • Eastman Chemical Company
      • Evonik Industries AG
      • Ferro Corporation
      • FibroGen Incorporated
      • FLAVORx Incorporated
      • FMC Corporation
      • GELITA AG
      • Generichem Corporation
      • Huber (JM) Corporation
      • Huntsman Corporation
      • Ingredion Incorporated
      • Innophos Holdings Incorporated
      • Kraft Foods Group Incorporated
      • Kuraray Company Limited
      • Ligand Pharmaceuticals Incorporated
      • LyondellBasell Industries NV
      • Merck KGaA
      • Mutchler Incorporated
      • Nitta Gelatin Incorporated
      • NutraSweet Company
      • Pfanstiehl Incorporated
      • Procter & Gamble Company
      • Rettenmaier (J.) &Söhne GmbH & Company KG
      • Roquette Frères SA
      • Royal Dutch Shell plc
      • Sasol Limited
      • Shin-Etsu Chemical Company Limited
      • Solvay SA
      • Stepan Company
      • Tate & Lyle plc
      • Tessenderlo Group NV
      • USG Corporation
      • Wacker Chemie AG
    • Other Companies Mentioned in Study

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