Nephrotic syndrome - Pipeline Insight, 2021

DelveInsight’s, “Nephrotic syndrome - Pipeline Insight, 2021,” report provides comprehensive insights about 3+ companies and 3+ pipeline drugs in Nephrotic syndrome pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.

Geography Covered
• Global coverage

Nephrotic syndrome Understanding
Nephrotic syndrome: Overview
Nephrotic syndrome is a group of symptoms that show your kidneys are not working as well as they should. These symptoms include too much protein in your urine, not enough protein in your blood, too much fat or cholesterol in your blood, and swelling. Anyone can get nephrotic syndrome but it is slightly more common in men than in women. In children, it happens most often between the ages of 2 and 6. The most common primary cause of nephrotic syndrome in adults is a disease called focal segmental glomerulosclerosis (FSGS). The only way to know for sure whether you have FSGS is to get a kidney biopsy. Even when treated, most people with FSGS will eventually develop kidney failure and will need to start dialysis or have a kidney transplant to live. After transplant, there is still a chance that FSGS will return and you may lose your new kidney.

""Nephrotic syndrome - Pipeline Insight, 2021"" report by DelveInsight outlays comprehensive insights of present scenario and growth prospects across the indication. A detailed picture of the Nephrotic syndrome pipeline landscape is provided which includes the disease overview and Nephrotic syndrome treatment guidelines. The assessment part of the report embraces, in depth Nephrotic syndrome commercial assessment and clinical assessment of the pipeline products under development. In the report, detailed description of the drug is given which includes mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, Nephrotic syndrome collaborations, licensing, mergers and acquisition, funding, designations and other product related details.

Report Highlights
• The companies and academics are working to assess challenges and seek opportunities that could influence Nephrotic syndrome R&D. The therapies under development are focused on novel approaches to treat/improve Nephrotic syndrome.

Nephrotic syndrome Emerging Drugs Chapters
This segment of the Nephrotic syndrome report encloses its detailed analysis of various drugs in different stages of clinical development, including phase II, I, preclinical and Discovery. It also helps to understand clinical trial details, expressive pharmacological action, agreements and collaborations, and the latest news and press releases.

Nephrotic syndrome Emerging Drugs
• Belimumab: GlaxoSmithKline
Belimumab is a fully human monoclonal antibody that has been developed by GlaxoSmithKline/MedImmune. Currently, it is in Phase II stage of clinical trial evaluation to treat Nephrotic syndrome.
Further product details are provided in the report……..

Nephrotic syndrome: Therapeutic Assessment
This segment of the report provides insights about the different Nephrotic syndrome drugs segregated based on following parameters that define the scope of the report, such as:
• Major Players in Nephrotic syndrome
There are approx. 3+ key companies which are developing the therapies for Nephrotic syndrome. The companies which have their Nephrotic syndrome drug candidates in the most advanced stage, i.e. phase II include, GlaxoSmithKline.

• Phases
DelveInsight’s report covers around 3+ products under different phases of clinical development like
• Late stage products (Phase III)
• Mid-stage products (Phase II)
• Early-stage product (Phase I) along with the details of
• Pre-clinical and Discovery stage candidates
• Discontinued & Inactive candidates

• Route of Administration
Nephrotic syndrome pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as
• Oral
• Parenteral
• intravenous
• Subcutaneous
• Topical.
• Molecule Type

Products have been categorized under various Molecule types such as
• Monoclonal Antibody
• Peptides
• Polymer
• Small molecule
• Gene therapy
• Product Type
Drugs have been categorized under various product types like Mono, Combination and Mono/Combination.

Nephrotic syndrome: Pipeline Development Activities
The report provides insights into different therapeutic candidates in phase II, I, preclinical and discovery stage. It also analyses Nephrotic syndrome therapeutic drugs key players involved in developing key drugs.
Pipeline Development Activities
The report covers the detailed information of collaborations, acquisition and merger, licensing along with a thorough therapeutic assessment of emerging Nephrotic syndrome drugs.

Nephrotic syndrome Report Insights
• Nephrotic syndrome Pipeline Analysis
• Therapeutic Assessment
• Unmet Needs
• Impact of Drugs

Nephrotic syndrome Report Assessment
• Pipeline Product Profiles
• Therapeutic Assessment
• Pipeline Assessment
• Inactive drugs assessment
• Unmet Needs

Key Questions
Current Treatment Scenario and Emerging Therapies:
• How many companies are developing Nephrotic syndrome drugs?
• How many Nephrotic syndrome drugs are developed by each company?
• How many emerging drugs are in mid-stage, and late-stage of development for the treatment of Nephrotic syndrome?
• What are the key collaborations (Industry–Industry, Industry–Academia), Mergers and acquisitions, licensing activities related to the Nephrotic syndrome therapeutics?
• What are the recent trends, drug types and novel technologies developed to overcome the limitation of existing therapies?
• What are the clinical studies going on for Nephrotic syndrome and their status?
• What are the key designations that have been granted to the emerging drugs?

Key Players
• GlaxoSmithKline
• Goldfinch Bio, Inc.
• Travere Therapeutics, Inc.
• Aurinia Pharmaceuticals
• Bristol-Myers Squibb
• ChemoCentryx
• SynAct Pharma AB
Key Products
• Belimumab
• GFB-887
• RE-021
• Voclosporin
• Abatacept
• AP1189


Introduction
Executive Summary
Nephrotic syndrome: Overview
• Causes
• Mechanism of Action
• Signs and Symptoms
• Diagnosis
• Disease Management
Pipeline Therapeutics
• Comparative Analysis
Therapeutic Assessment
• Assessment by Product Type
• Assessment by Stage and Product Type
• Assessment by Route of Administration
• Assessment by Stage and Route of Administration
• Assessment by Molecule Type
• Assessment by Stage and Molecule Type
Nephrotic syndrome – DelveInsight’s Analytical Perspective
Mid Stage Products (Phase II)
• Comparative Analysis
Belimumab: GlaxoSmithKline
• Product Description
• Research and Development
• Product Development Activities
Drug profiles in the detailed report…..
Early Stage Products (Phase I)
• Comparative Analysis
Drug name: Company name
• Product Description
• Research and Development
• Product Development Activities
Drug profiles in the detailed report…..
Inactive Products
• Comparative Analysis
Nephrotic syndrome Key Companies
Nephrotic syndrome Key Products
Nephrotic syndrome- Unmet Needs
Nephrotic syndrome- Market Drivers and Barriers
Nephrotic syndrome- Future Perspectives and Conclusion
Nephrotic syndrome Analyst Views
Nephrotic syndrome Key Companies
Appendix
Introduction
Executive Summary
Nephrotic syndrome: Overview
• Causes
• Mechanism of Action
• Signs and Symptoms
• Diagnosis
• Disease Management
Pipeline Therapeutics
• Comparative Analysis
Therapeutic Assessment
• Assessment by Product Type
• Assessment by Stage and Product Type
• Assessment by Route of Administration
• Assessment by Stage and Route of Administration
• Assessment by Molecule Type
• Assessment by Stage and Molecule Type
Nephrotic syndrome – DelveInsight’s Analytical Perspective
In-depth Commercial Assessment
• Nephrotic syndrome companies’ collaborations, Licensing, Acquisition -Deal Value Trends
Nephrotic syndrome Collaboration Deals
• Company-Company Collaborations (Licensing / Partnering) Analysis
• Company-University Collaborations (Licensing / Partnering) Analysis
Mid Stage Products (Phase II)
• Comparative Analysis
Belimumab: GlaxoSmithKline
• Product Description
• Research and Development
• Product Development Activities
Drug profiles in the detailed report…..
Early Stage Products (Phase I)
• Comparative Analysis
Drug name: Company name
• Product Description
• Research and Development
• Product Development Activities
Drug profiles in the detailed report…..
Inactive Products
• Comparative Analysis
Nephrotic syndrome Key Companies
Nephrotic syndrome Key Products
Nephrotic syndrome- Unmet Needs
Nephrotic syndrome- Market Drivers and Barriers
Nephrotic syndrome- Future Perspectives and Conclusion
Nephrotic syndrome Analyst Views
Nephrotic syndrome Key Companies
Appendix
Table 1 Total Products for Nephrotic syndrome
Table 2 Late Stage Products
Table 3 Mid Stage Products
Table 4 Early Stage Products
Table 5 Pre-clinical & Discovery Stage Products
Table 6 Assessment by Product Type
Table 7 Assessment by Stage and Product Type
Table 8 Assessment by Route of Administration
Table 9 Assessment by Stage and Route of Administration
Table 10 Assessment by Molecule Type
Table 11 Assessment by Stage and Molecule Type
Table 12 Inactive Products
Figure 1 Total Products for Nephrotic syndrome
Figure 2 Late Stage Products
Figure 3 Mid Stage Products
Figure 4 Early Stage Products
Figure 5 Preclinical and Discovery Stage Products
Figure 6 Assessment by Product Type
Figure 7 Assessment by Stage and Product Type
Figure 8 Assessment by Route of Administration
Figure 9 Assessment by Stage and Route of Administration
Figure 10 Assessment by Molecule Type
Figure 11 Assessment by Stage and Molecule Type
Figure 12 Inactive Products

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