Acute Kidney Injury (AKI) - Epidemiology Forecast - 2030

DelveInsight’s ‘Acute Kidney Injury (AKI) - Epidemiology Forecast–2030’ report delivers an in-depth understanding of the disease, historical and forecasted Acute Kidney Injury (AKI) epidemiology in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan.

Acute Kidney Injury (AKI) Understanding
AKI is characterized by a rapid fall in glomerular filtration rate, clinically manifest as an abrupt and sustained rise in urea and creatinine. Life threatening consequences include volume overload, hyperkalaemia, and metabolic acidosis. As per the American Kidney Foundation organization, AKI was formerly called Acute Kidney Injury. The disease leads to abrupt loss of kidney function, leading to the retention of waste products, electrolyte disturbances, and volume status changes. Acute Kidney Injury is classified into three different phases including prerenal, postrenal and intrinsic renal. Pre-renal ARI is characterized by inadequate blood circulation to the kidneys, which leaves them to clean the body properly. Post-renal is characterized by acute obstruction to urinary flow which increases intratubular pressure and decreases GFR. Intrinsic AKI is the third type, which shows direct damage to kidneys by inflammation, toxins, drugs, and infections. The risk factors associated with AKI include age, exposure to nephrotoxins, family history, race and ethnicity, gender and others.

Acute Kidney Injury (AKI) Epidemiology Perspective by DelveInsight
The disease epidemiology covered in the report provides historical as well as forecasted epidemiology segmented by Incident Cases of Acute Kidney Injury, Discharge Diagnosed Cases of Acute Kidney Injury, Stage-Wise Discharged Diagnosed Cases of Acute Kidney Injury, Risk Factor Associated Acute Kidney Injury Cases and Renal Transplantation Associated Delayed Graft Function scenario of Acute Kidney Injury (AKI) in the 7MM covering the United States, EU5 countries (Germany, France, Italy, Spain, and United Kingdom) and Japan from 2017 to 2030.

Acute Kidney Injury (AKI) Detailed Epidemiology Segmentation
• The total incident population of Acute Kidney Injury in the seven major markets was found to be 1,525,519 in 2017. In the United States the incident population of Acute Kidney Injury was 895,078 in 2017, which is expected to increase in the forecast period (2020–2030).
• DelveInsight also estimates higher Diagnosed Discharge Cases of AKI in the United States with 532,830 diagnosed discharge cases found in 2017.
• According to KIDGO staging; stage II AKI corresponds to the relatively higher diagnosed discharge population with 223,789 cases in 2017 in the United States.

Scope of the Report
• The report covers the descriptive overview of Acute Kidney Injury (AKI), explaining its causes, signs and symptoms, pathophysiology.
• The report provides insight into the 7MM historical and forecasted patient pool covering the United States, EU5 countries (Germany, France, Italy, Spain, and United Kingdom) and Japan.
• The report assesses the disease risk and burden and highlights the unmet needs of Acute Kidney Injury (AKI).
• The report provides the segmentation of the disease epidemiology for 7MM by Total Prevalent Cases of Acute Kidney Injury (AKI), Total Diagnosed and Treated Cases of Acute Kidney Injury (AKI).

Report Highlights
• Eleven Year Forecast of Acute Kidney Injury (AKI)
• Acute Kidney Injury (AKI) Epidemiology Segmentation (The segmentation consists of wider landscape covering different scenarios for developing the AKI model)
• The report covers Stage-Wise Discharge Diagnosed Cases of Acute Kidney Injury, which includes stages of AKI such as Stage I, Stage II and Stage III. Out of all the stages, Stage II showed the highest diagnosed discharge cases of AKI.
• The report also include Risk Factor Associated Acute Kidney Injury Cases, wherein several risk factors such as Coronary artery disease, Chronic kidney disease, Chronic lung disease, Sepsis, Cardiac surgery, etc are throroughly studied.
• An important segment of the report, i.e., Renal Transplantation Associated Delayed Graft Function provides scenario of Delayed Graft Function cases who undergo Renal Transplantation.
• 7MM Coverage
Key Questions Answered
• What is the disease risk, burden and unmet needs of Acute Kidney Injury (AKI)?
• What is the historical Acute Kidney Injury (AKI) patient pool in the United States, EU5 (Germany, France, Italy, Spain, and the UK) and Japan?
• What would be the forecasted patient pool of Acute Kidney Injury (AKI) at the 7MM level?
• What will be the growth opportunities across the 7MM with respect to the patient population pertaining to Acute Kidney Injury (AKI)?
• Out of the above-mentioned countries, which country would have the highest prevalent population of Acute Kidney Injury (AKI) during the forecast period (2020–2030)?
• At what CAGR the population is expected to grow across the 7MM during the forecast period (2020–2030)?

Reasons to buy
The Acute Kidney Injury (AKI) report will allow the user to -
• Develop business strategies by understanding the trends shaping and driving the 7MM Acute Kidney Injury (AKI) market.
• Quantify patient share distribution in the 7MM for Acute Kidney Injury (AKI).
• The Acute Kidney Injury (AKI) epidemiology report and model were written and developed by Masters and Ph.D. level epidemiologists.
• The Acute Kidney Injury (AKI) epidemiology model developed by DelveInsight is easy to navigate, interactive with dashboards, and epidemiology based on transparent and consistent methodologies. Moreover, the model supports data presented in the report and showcases disease trends over the eleven-year forecast period using reputable sources.
Key Assessments

• Patient Segmentation
• Disease Risk and Burden
• Risk of disease by the segmentation

• Factors driving growth in a specific patient population
Geographies Covered
• The United States
• EU5 (Germany, France, Italy, Spain, and the United Kingdom)
• Japan
Study Period: 2017–2030


1. Key Insights
2. Acute Kidney Injury Market (AKI): Overview at a Glance
3. Acute Kidney Injury (AKI): Disease Background and Overview
3.1. Introduction
3.2. Symptoms
3.3. Types of Acute Kidney Injury
3.4. Stages Classification
3.5. Risk Factors
3.6. Etiology
3.7. Pathophysiology
3.8. Biomarkers
3.9. Diagnosis
4. Epidemiology and Patient Population
4.1. Key Findings
4.2. 7MM Total Incident Patient Population of AKI
4.3. 7MM Total Discharge Diagnosed Population of AKI
5. United States
5.1. Assumptions and Rationale
5.2. Acute Kidney Injury Incident Cases in the US
5.3. Acute Kidney Injury Discharge Diagnosed Cases in the US
5.4. Acute Kidney Injury Stage-Wise Discharged Diagnosed Cases in the US
5.5. Acute Kidney Injury Risk Factor Associated Cases in the US
5.6. Acute Kidney Injury Renal Transplantation Associated Delayed Graft Function Cases in the US
6. EU5
6.1. Assumptions and Rationale
6.2. Germany
6.2.1. Acute Kidney Injury Incident Cases in Germany
6.2.2. Acute Kidney Injury Discharge Diagnosed Cases in Germany
6.2.3. Acute Kidney Injury Stage-Wise Discharged Diagnosed Cases in Germany
6.2.4. Acute Kidney Injury Risk Factor Associated Cases in Germany
6.2.5. Acute Kidney Injury Renal Transplantation Associated Delayed Graft Function Cases in Germany
6.3. France
6.3.1. Acute Kidney Injury Incident Cases in France
6.3.2. Acute Kidney Injury Discharge Diagnosed Cases in France
6.3.3. Acute Kidney Injury Stage-Wise Discharge Diagnosed Cases in France
6.3.4. Acute Kidney Injury Risk Factor Associated Cases in France
6.3.5. Acute Kidney Injury Renal Transplantation Associated Delayed Graft Function Cases in France
6.4. Italy
6.4.1. Acute Kidney Injury Incident Cases in Italy
6.4.2. Acute Kidney Injury Discharge Diagnosed Cases in Italy
6.4.3. Acute Kidney Injury Stage-Wise Discharge Diagnosed Cases in Italy
6.4.4. Acute Kidney Injury Risk Factor Associated Cases in Italy
6.4.5. Acute Kidney Injury Renal Transplantation Associated Delayed Graft Function Cases in Italy
6.5. Spain
6.5.1. Acute Kidney Injury Incident Cases in Spain
6.5.2. Acute Kidney Injury Discharge Diagnosed Cases in Spain
6.5.3. Acute Kidney Injury Stage-Wise Discharge Diagnosed Cases in Spain
6.5.4. Acute Kidney Injury Risk Factor Associated Cases in Spain
6.5.5. Acute Kidney Injury Renal Transplantation Associated Delayed Graft Function Cases in Spain
6.6. United Kingdom
6.6.1. Acute Kidney Injury Incident Cases in the UK
6.6.2. Acute Kidney Injury Discharge Diagnosed Incident Cases in the UK
6.6.3. Acute Kidney Injury Stage-Wise Discharge Diagnosed Cases in the UK
6.6.4. Acute Kidney Injury Risk Factor Associated Cases in the UK
6.6.5. Acute Kidney Injury Renal Transplantation Associated Delayed Graft Function Cases in the UK
7. Japan
7.1.1. Assumptions and Rationale
7.1.2. Acute Kidney Injury Incident Cases in Japan
7.1.3. Acute Kidney Injury Discharge Diagnosed Cases Japan
7.1.4. Acute Kidney Injury Stage-Wise Discharge Diagnosed Cases in Japan
7.1.5. Acute Kidney Injury Risk Factor Associated Cases in Japan
7.1.6. Acute Kidney Injury Renal Transplantation Associated Delayed Graft Function Cases in Japan
8. Appendix
8.1. Report Methodology
9. DelveInsight Capabilities
10. Disclaimer
11. About DelveInsight
Table 1 Risk, Injury, Failure, Loss, and End-stage Kidney (RIFLE) classification
Table 2 KDIGO Criteria
Table 3 Causes of AKI: Exposures and Susceptibilities for non-specific AKI
Table 4 Biomarkers of AKI
Table 5 RIFLE Criteria for AKI
Table 6 AKIN Criteria for AKI
Table 7 KDIGO Criteria for AKI
Table 8 Total Incident Population of AKI in the 7MM (2017–2030)
Table 9 Total Discharge Diagnosed Population of AKI in the 7MM (2017–2030)
Table 10 AKI Incident Cases in the US (2017–2030)
Table 11 AKI Discharge Diagnosed Cases in the US (2017–2030)
Table 12 AKI Stage-Wise Discharged Diagnosed Cases in the US (2017–2030)
Table 13 AKI Risk Factor Associated Cases in the US (2017–2030)
Table 14 AKI Renal Transplantation Associated Delayed Graft Function Cases in the US (2017–2030)
Table 15 AKI Incident Cases in Germany (2017–2030)
Table 16 AKI Discharge Diagnosed Cases in Germany (2017–2030)
Table 17 AKI Stage-Wise Incident Cases in Germany (2017–2030)
Table 18 AKI Risk Factor Associated Cases in Germany (2017–2030)
Table 19 AKI Renal Transplantation Associated Delayed Graft Function Cases in Germany (2017–2030)
Table 20 AKI Incident Cases in France (2017–2030)
Table 21 AKI Discharge Diagnosed Cases in France (2017–2030)
Table 22 AKI Stage-Wise Discharge Diagnosed Cases in France (2017–2030)
Table 23 AKI Risk Factor Associated Cases in France (2017–2030)
Table 24 AKI Renal Transplantation Associated Delayed Graft Function Cases in France (2017–2030)
Table 25 AKI Incident Cases in Italy (2017–2030)
Table 26 AKI Discharge Diagnosed Cases in Italy (2017–2030)
Table 27 AKI Stage-Wise Discharge Diagnosed Cases in Italy (2017–2030)
Table 28 AKI Risk Factor Associated Cases in Italy (2017–2030)
Table 29 AKI Renal Transplantation Associated Delayed Graft Function Cases in Italy (2017–2030)
Table 30 AKI Incident Cases in Spain (2017–2030)
Table 31 AKI Discharge Diagnosed Cases in Spain (2017–2030)
Table 32 AKI Stage-Wise Discharge Diagnosed Cases in Spain (2017–2030)
Table 33 AKI Risk Factor Associated Cases in Spain (2017–2030)
Table 34 AKI Renal Transplantation Associated Delayed Graft Function Cases in Spain (2017–2030)
Table 35 AKI Incident Cases in the UK (2017–2030)
Table 36 AKI Discharge Diagnosed Cases in the UK (2017–2030)
Table 37 AKI Stage-Wise Discharge Diagnosed Cases in the UK (2017–2030)
Table 38 AKI Risk Factor Associated Cases in the UK (2017–2030)
Table 39 AKI Renal Transplantation Associated Delayed Graft Function Cases in the UK (2017–2030)
Table 40 AKI Incident Cases in Japan (2017–2030)
Table 41 AKI Discharge Diagnosed Cases in Japan (2017–2030)
Table 42 AKI Stage-Wise Discharge Diagnosed Cases in Japan (2017–2030)
Table 43 AKI Risk Factor Associated Cases in Japan (2017–2030)
Table 44 AKI Renal Transplantation Associated Delayed Graft Function Cases in Japan (2017–2030)
Figure 1 Types of Acute Kidney Injury
Figure 2 Risk factors associated with Acute Kidney Injury
Figure 3 Common Causes of AKI
Figure 4 Pathophysiology of AKI
Figure 5 Biomarkers of AKI
Figure 6 Total Incident Patient Population of AKI in the 7MM (2017–2030)
Figure 7 Total Discharge Diagnosed Population of AKI in the 7MM (2017–2030)
Figure 8 AKI Incident Cases in the US (2017–2030)
Figure 9 AKI Discharge Diagnosed Cases in the US (2017–2030)
Figure 10 AKI Stage-Wise Discharged Diagnosed Cases in the US (2017–2030)
Figure 11 AKI Risk Factor Associated Cases in the US (2017–2030)
Figure 12 AKI Renal Transplantation Associated Delayed Graft Function Cases in the US (2017–2030)
Figure 13 AKI Incident Cases in Germany (2017–2030)
Figure 14 AKI Discharge Diagnosed Cases in Germany (2017–2030)
Figure 15 AKI Stage-Wise Incident Cases in Germany (2017–2030)
Figure 16 AKI Risk Factor Associated Cases in Germany (2017–2030)
Figure 17 AKI Renal Transplantation Associated Delayed Graft Function Cases in Germany (2017–2030)
Figure 18 AKI Incident Cases in France (2017–2030)
Figure 19 AKI Discharge Diagnosed Cases in France (2017–2030)
Figure 20 AKI Stage-Wise Discharge Diagnosed Cases in France (2017–2030)
Figure 21 AKI Risk Factor Associated Cases in France (2017–2030)
Figure 22 AKI Renal Transplantation Associated Delayed Graft Function Cases in France (2017–2030)
Figure 23 AKI Incident Cases in Italy (2017–2030)
Figure 24 AKI Discharge Diagnosed Cases in Italy (2017–2030)
Figure 25 AKI Stage-Wise Discharge Diagnosed Cases in Italy (2017–2030)
Figure 26 AKI Risk Factor Associated Cases in Italy (2017–2030)
Figure 27 AKI Renal Transplantation Associated Delayed Graft Function Cases in Italy (2017–2030)
Figure 28 AKI Incident Cases in Spain (2017–2030)
Figure 29 AKI Discharge Diagnosed Cases in Spain 2017–2030)
Figure 30 AKI Stage-Wise Discharge Diagnosed Cases in Spain (2017–2030)
Figure 31 AKI Risk Factor Associated Cases in Spain (2017–2030)
Figure 32 AKI Renal Transplantation Associated Delayed Graft Function Cases in Spain (2017–2030)
Figure 33 AKI Incident Cases in the UK (2017–2030)
Figure 34 AKI Discharge Diagnosed Cases in the UK (2017–2030)
Figure 35 AKI Stage-Wise Discharge Diagnosed Cases the UK (2017–2030)
Figure 36 AKI Risk Factor Associated Cases in the UK (2017–2030)
Figure 37 AKI Renal Transplantation Associated Delayed Graft Function Cases in the UK (2017–2030)
Figure 38 AKI Incident Cases of in Japan (2017–2030)
Figure 39 AKI Discharge Diagnosed Incident Cases in Japan (2017–2030)
Figure 40 AKI Stage-Wise Discharge Diagnosed Cases in Japan (2017–2030)
Figure 41 AKI Risk Factor Associated Cases in Japan (2017–2030)
Figure 42 AKI Renal Transplantation Associated Delayed Graft Function Cases in Japan (2017–2030)
Figure 43 Global Mortality of AKI

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