Global Divalproex Sodium Market - 2021-2028

Global Divalproex Sodium Market - 2021-2028

Divalproex Sodium Market Overview
• The global divalproex sodium market size was valued US$ XX billion in 2019 and is estimated to reach US$ XX billion by 2028, growing at a CAGR of XX % during the forecast period (2021-2028).
• Divalproex sodium is an anti-epileptic drug approved by Food and Drug Administrator (FDA) used to treat migraine headaches, manic episodes of bipolar disorders, and certain types of seizures. It is known for its anticonvulsant properties for the treatment of epilepsy.
• Divalproex Sodium Market Dynamics
• The divalproex sodium market growth is driven by the growing prevalence of bipolar disorders, increasing patient pool with epilepsy and migraine headaches, and growing government initiatives and increasing research and development for the introduction of new products.
• Increasing prevalence of bipolar disorders around the globe is expected to drive the growth in the forecast period
• The increasing prevalence of bipolar disorders around the globe is propelling the divalproex sodium market growth. For instance, according to a study done by National Alliance on Mental Illness in 2017, the average age-of-onset of bipolar disorder is about 25, but it can occur in the teens, or more uncommonly, in childhood. The condition affects men and women equally, with about 2.8% of the U.S. population diagnosed with bipolar disorder and nearly 83% of cases classified as severe.
• Increasing patient pool with epilepsy and migraine headaches is expected to drive the growth in the forecast period
• The rising patient pool worldwide affected with epilepsy and migraine headaches is expected to boost demand for the divalproex sodium market significantly. For instance, according to the World Health Organization 2018 key facts, around 50 million people were globally affected with epilepsy, making it one of the most common neurological diseases, and around 80% of the people with epilepsy live in low- and middle-income countries.
• According to the Migraine Trust Facts and Figures estimates, the global prevalence of migraine was 14.7% for the year 2013, that’s around 1 in 7 people. Furthermore, increasing awareness regarding diseases and various government initiatives to prevent head migraines is expected to propel the divalproex sodium market size.
• Increasing adverse effects of divalproex sodium is likely to hinder the market growth
• The FDA gave a black boxed warning due to the hepatotoxicity, pancreatitis, and high fetal risk associated with the use of divalproex sodium tablets and other known adverse reactions such as congenital disabilities, neurobehavioral adverse effects, and suicidal behavior are expected to restrain the divalproex sodium market growth.
• COVID-19 Impact Analysis
• The COVID-19 pandemic has been continuing to transform the growth of various markets, the immediate impact of the outbreak is varied. While a few industries registered a drop in demand, numerous other markets may continue to remain unscathed and show promising growth opportunities. Initially, the outbreak of COVID-19 showed an impact on the divalproex sodium market by directly affecting its production, creating supply chain disruptions, and creating a financial impact on firms due to social distancing and lockdown measures taken by the government. However, demand for divalproex sodium is expected to rise at a considerable pace in the coming years.
• Divalproex Sodium Market Segment Analysis
• The tablet segment is expected to hold largest share in this market segment
• Divalproex sodium oral tablet is available in brand names Depakote ER and Depakote. Divalproex sodium is also used in various combinational therapies. The recommended initial dosage of Depakote for the treatment of bipolar disorders is 750 mg daily, whereas for complex partial seizures, the initial dosage starts with 10 to 15 mg/kg/day. Also, recommended starting dose for migraine headache is 250 mg twice daily to achieve a therapeutic response. Divalproex sodium extended-release tablets are valproate and are indicated for treating acute manic or mixed episodes associated with bipolar disorder, with or without psychotic features.
• The epilepsy and migraine headaches segment are expected to hold largest share in this market segment
• Epilepsy is one of the most common nervous system disorders which causes seizures. When there is an enduring predisposition to seizures, it is called epilepsy. It can affect people of any age, from children to adults of all races and backgrounds. For instance, seizures and epilepsy are some of the challenging health issues facing by many children. An epileptic seizure is said to be an abnormal electrical activity in your brain. It is a state of neurological activity that feels like a shock wave traveling through the brain, and the recurrence of these repetitive unprovoked seizures is called epilepsy.
• Migraine is a medical condition that involves severe, recurring headaches and other symptoms. Before the headache, there may be sensory changes that are known as an aura. As per a 2018 article published by the American Academy of Family Physicians (AAFP), more than 15% of adults in the United States had experienced a migraine episode or a severe headache within three months. According to Migraine Research Foundation, 12% of the population, including children, suffers from migraines and around 18% of American women, 6% of men, and 10% of children experience migraines.
• The rise in people getting affected by epilepsy and migraine headaches is projected to account for the largest market share during the forecast period. Epilepsy is triggered due to certain health conditions like brain tumors, strokes, brain infections, neurological defects, lack of oxygen to the brain, hyperpyrexia etc. Traumatic head and brain injuries, specific genetic conditions, smoking and drinking alcohol also led to epilepsy. At the same time, migraine is triggered due to hormonal changes, emotional triggers such as stress, depression, anxiety, Dietary factors like alcohol, caffeine, medications, and environmental factors.
• In the present scenario, the living styles of people have induced anxiety and stress in their daily life due to which patient pool getting affected by epilepsy and migraine headaches is expected to increase during the forecast period and contribute as a driving factor divalproex sodium market.
• The retail pharmacies segment is expected to hold largest share in this market segment
• The retail Pharmacies segment is expected to dominate during the forecast period. Divalproex sodium drugs are easily, readily available in retail pharmacies as the generic medicine. Retail pharmacies offer convenient services, including home delivery of medicines and availability of all types of drugs and medicines. Moreover, consumer preference for easy availability of products due to busy lifestyles and hectic work schedules is anticipated to boost market growth.
• Divalproex Sodium Market Geographical Analysis
• North America region holds the largest market share of global divalproex sodium market
• In the North American region, the United States divalproex sodium market holds the major share. Rising government initiatives and increasing research and development for the introduction of novel products are expected to aid in the growth of the divalproex sodium market in the region. For instance, according to the Centers for Disease Control and Prevention, approximately 3 million adults and 470,000 children in the United States have epilepsy. According to a survey of 11 countries performed by Therapeutic Advances in Psychopharmacology, 2018, the lifetime prevalence of bipolar disorder was 2.4%, and out of that, 1% of prevalence was found in the United States, which is higher than other countries in the survey.
• Divalproex Sodium Market Competitive Landscape
• The global divalproex sodium market is moderately competitive with presence of global companies. Some of the key players which are contributing to the growth of the market include Zydus Cadila Pharmaceuticals, Inc., AbbVie Inc., Mylan N.V., Abbott Laboratories, Dr. Reddy’s Laboratories Ltd., Lupin Limited, Orchid Chemicals & Pharmaceuticals Limited, Sun Pharmaceutical Industries Ltd., Teva Pharmaceutical Industries Ltd., and Abbott Laboratories. The major players are adopting several growth strategies such as product launches, acquisitions, and collaborations, which are contributing to the growth of the market globally. For instance, in 2019 Lupin received the approval for divalproex sodium extended-release tablets USP 250 mg and 500 mg from the US FDA for commercializing generic equivalent of Depakote extended-release Tablets, 250 mg, and 500 mg, of AbbVie.
• Divalproex Sodium Market Key Companies to Watch
• Zydus Cadila Pharmaceuticals, Inc
• Overview: Zydus Cadila, a leading Indian Pharmaceutical company is a fully integrated, global healthcare provider. With in-depth domain expertise in the field of healthcare, it has strong capabilities across the spectrum of the pharmaceutical value chain. The origin of the company dates all the way back to the 1950s. The company was founded in the year 1952 by Mr. Ramanbhai B. Patel (late), a first-generation entrepreneur and a doyen in the field of Indian Pharmaceuticals.
• Product Portfolio: The company portfolio includes New Chemical Entities, Biologics, Vaccines.
• Key developments: In 2017, Zydus Cadila acquired Sentynl Therapeutics, a U.S.-based pharma company specialized in marketing of products in the pain management segment.
• Why Purchase the Report?
• Visualize the composition of the divalproex sodium market segmentation by application, by dosage form and by distribution channel highlighting the key commercial assets and players.
• Identify commercial opportunities in divalproex sodium market by analyzing trends and co-development deals.
• Excel data sheet with thousands of data points of divalproex sodium market - level 4/5 segmentation.
• PDF report with the most relevant analysis cogently put together after exhaustive qualitative interviews and in-depth market study.
• Product mapping in excel for the key product of all major market players
• The global divalproex sodium market report would provide an access to an approx. 61 market data table, 52 figures and 200 pages.
• Target Audience
• Service Providers/ Buyers
• Industry Investors/Investment Bankers
• Education & Research Institutes
• Research Professionals
• Emerging Companies
• Manufacturers
• Market Segmentation:
• Global Divalproex Sodium Market- By Dosage Form
• Tablet
• Capsule
• Syrup
• Global Divalproex Sodium Market- By Application
• Epilepsy and Migraine Headaches
• Manic Depressive Illness
• Others
• Global Divalproex Sodium Market- By Distribution Channel
• Hospital Pharmacies
• Retail Pharmacies
• Online Pharmacies
• Global Divalproex Sodium Market - By Region
• North America
• Europe
• Asia-Pacific
• Middle East & Africa
• South America