Market Research Logo

Global PARP Inhibitor Market: Size, Trends and Forecasts (2016-2020)

Global PARP Inhibitor Market: Size, Trends and Forecasts (2016-2020)

Scope of the Report

The report titled “Global PARP Inhibitor Market: Size, Trends and Forecasts (2016-2020)” provides an in-depth analysis of the global PARP inhibitor market with detailed analysis of market size on the basis of value along with the comprehensive examination of each of the segments of the market, namely, Lynparza, Niraparib, Rucaparib, Talazoparib and Veliparib.

The report analyses the global Lynparza market in detail along with the regional analysis as it is the only commercialized product in the market. The clinical trials of Niraparib, Rucaparib, Talazoparib and Veliparib are also summarized along with the anticipated market commencement for each of the products.

The report provides detailed market potential of PARP inhibitor in Ovarian cancer, Breast cancer, Prostate cancer and Pancreatic cancer. This section provides the detailed analysis of the clinical trials of various PARP inhibitors for the concerned cancer treatment.

The report also assesses the key opportunities in the market and outlines the factors that are and will be driving the growth of the industry. Growth of the overall global PARP inhibitor market has also been forecasted for the period 2016-2020, taking into consideration the research & development, the growth drivers and the current and future trends. The competition in the global PARP inhibitor market is stiff and dominated by the big players like AstraZeneca. Further, key players in the market, AbbVie, Clovis Oncology, Medivation and Tesaro are also profiled with their financial information and respective business strategies.

Regional Coverage

Global

Company Coverage

AstraZeneca PLC
AbbVie Inc.
Clovis Oncology, Inc.
Medivation, Inc.
Tesaro, Inc. 

Executive Summary

The global PARP inhibitor market has flourished since 2015 as in late 2014, the first PARP inhibitor product was launched and projections are made that the market would rise in the next five years i.e. 2016-2020 tremendously. The market is spread across the globe with the United States and Europe dominating the market.

The PARP inhibitor market can be segmented on the basis of the products into Lynparza, Niraparib, Rucaparib, Talazoparib and Veliparib. Currently, Lynparza is the only commercialized product in the market while other four products are in the development/trial stage. The market for Veliparib is expected to flourish since 2017 while the markets for Niraparib, Rucaparib and Talazoparib is expected to commence from 2018.

The major growth drivers for the global PARP inhibitor market are: rise in cancer incidences and PARP inhibitors in clinical routine. Despite the market is governed by growth drivers, there are certain challenges faced by the market such as: side-effects of PARP inhibitors and resistance to PARP inhibition. Some of the recent and major trends in the market include, various PARP inhibitors in the pipeline, inhibiting enzyme versus PARP trapping, the combination of PARP inhibitor & c-MET and pill burden likely to decline in the near future.


1. Executive Summary
2. Introduction
2.1 DNA Damage Response (DDR)
2.2 DNA Damage Response (DDR) Drug Portfolio
Table A: DDR Drug Portfolio
2.3 PARP Inhibitor
2.3.1 Introduction to PARP Inhibitor
Table 1: Role of PARP Inhibitor
2.3.2 Inhibiting PARP Mechanism
2.3.3 PARP Inhibitor as a Cancer Treatment
2.3.4 PARP Inhibitor Development
Table B: PARP Inhibitors in Development
3. Global Market Analysis
3.1 Global PARP Inhibitor Market by Value
Table 2: Global PARP Inhibitor Market by Value; 2015-2020E (US$ Million)
3.2 Global PARP Inhibitor Market by Segments
3.2.1 Global Lynparza Market Analysis
Ongoing Lynparza Trials
Table C: Ongoing Phase III and Phase II Lynparza Trials
Global Lynparza Market by Value
Table 3: Global Lynparza Market by Value; 2015-2020E (US$ Million)
Global Lynparza Market by Region
Table 4: Global Lynparza Market by Region; 2015 (%)
3.2.2 Global Niraparib Market Analysis
Ongoing Niraparib Trials
Table D: Ongoing Niraparib Trials
Global Niraparib Market by Value
Table 5: Global Niraparib Market by Value; 2018E-2020E (US$ Million)
3.2.3 Global Rucaparib Market Analysis
Ongoing Rucaparib Trials
Table E: Ongoing Phase III and Phase II Rucaparib Trials
Global Rucaparib Market by Value
Table 6: Global Rucaparib Market by Value; 2018E-2020E (US$ Million)
3.2.4 Global Talazoparib Market Analysis
Ongoing Talazoparib Trials
Table F: Ongoing Talazoparib Trials
Global Talazoparib Market by Value
Table 7: Global Talazoparib Market by Value; 2018E-2020E (US$ Million)
3.2.5 Global Veliparib Market Analysis
Ongoing Veliparib Trials
Table G: Ongoing Phase III and Phase II Veliparib Trials
Global Veliparib Market by Value
Table 8: Global Veliparib Market by Value; 2017E-2020E (US$ Million)
4. Global PARP Inhibitor Market Potential Analysis
4.1 Global PARP Inhibitor Market Potential
Table H: Global PARP Inhibitor Market Potential
4.2 Global Ovarian Cancer Market Opportunity
Table I: Phase III Ovarian Cancer Trials
4.3 Global Breast Cancer Market Opportunity
Table J: Phase III Breast Cancer Trials
4.4 Global Prostate Cancer Market Opportunity
Table K: Prostate Cancer Trials
4.5 Global Pancreatic Market Opportunity
Table L: Pancreatic Cancer Trials
5. Market Dynamics
5.1 Growth Drivers
5.1.1 Rise in Cancer Incidences
Table 9: Global Cancer Incidences; 2012-2020E (Million)
Table 10: Global Cancer Cases by Types of Cancer; 2012 (%)
5.1.2 PARP Inhibitors in Clinical Routine
5.2 Challenges
5.2.1 PARP Inhibitors Side-Effects
Table 11: PARP Inhibitor Side-Effects Profile
5.2.2 Resistance to PARP Inhibition
5.3 Market Trends
5.3.1 PARP Inhibitors in Pipeline
5.3.2 Inhibiting Enzyme and PARP Trapping
Table M: Enzyme Inhibition and PARP Trapping Capabilities of Each PARP
5.3.3 Combination of PARP Inhibitors and c-MET
5.3.4 PARP Inhibitor Pill Burden Likely to Decline
6. Competitive Landscape
Table N: Global PARP Inhibitor Major Companies Ongoing Phase III Trial
7. Company Profiling
7.1 AstraZeneca PLC
7.1.1 Business Overview
Table O: AstraZeneca Major Products
7.1.2 Financial Overview
Table 12: AstraZeneca Total Revenue; 2011-2015 (US$ Billion)
Table 13: AstraZeneca Total Revenue by Product Segments; 2015 (US$ Million)
Table 14: AstraZeneca Total Revenue of Products by Region; 2015 (%)
7.1.3 Business Strategy
7.2 AbbVie Inc.
7.2.1 Business Overview
7.2.2 Financial Overview
Table 15: AbbVie Total Revenue; 2011-2015 (US$ Billion)
Table 16: AbbVie Total Revenue by Products; 2015 (%)
Table 17: AbbVie Total Revenue by Region; 2015 (%)
7.2.3 Business Strategy
7.3 Clovis Oncology, Inc.
7.3.1 Business Overview
7.3.2 Financial Overview
Table 18: Clovis Research & Development Expenditure; 2011-2015 (US$ Million)
Table 19: Clovis Research & Development Expenditure by Products; 2015 (%)
7.3.3 Business Strategy
Table 16: Clovis Oncology Company Product Development Pipeline
7.4 Medivation, Inc.
7.4.1 Business Overview
7.4.2 Financial Overview
Table 20: Medivation Collaboration Revenue; 2011-2015 (US$ Million)
Table 21: Medivation Research & Development Expenditure; 2011-2015 (US$ Million)
Table 22: Medivation Research & Development Expenditure by Products; 2015 (%)
7.4.3 Business Strategy
7.5 Tesaro, Inc.
7.5.1 Business Overview
7.5.2 Financial Overview
Table 23: Tesaro Research & Development Expenditure; 2011-2015 (US$ Million)
Table 24: Tesaro Research & Development Expenditure by Products; 2015 (%)
7.5.3 Business Strategy

Download our eBook: How to Succeed Using Market Research

Learn how to effectively navigate the market research process to help guide your organization on the journey to success.

Download eBook

Share this report