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Single-cell Omics: Emerging Technologies and Markets

Single-cell Omics: Emerging Technologies and Markets

Report Scope:

The scope of this report includes single cell analysis technologies, applications, industries, major funding initiatives, patents and companies. The market sizes for single cell products are given for the years 2015, 2016, 2017 (estimated) and 2022 (forecasted).

This report reviews the single cell workflow steps and technologies and provides background on why single cell analysis is important. It then discusses some of the top research initiatives that are contributing to single cell applications. Market driving forces are also discussed.

The structure of several important industry subsectors is reviewed, as well as major industry acquisitions and strategic alliances from Jan. 2016 to Sept. 2017. Industry subsectors analyzed include target enrichment, droplet digital PCR, single cell DNA polymerase, DNA amplification, next generation sequencing (NGS) instruments, single cell proteomics, circulating tumor cell (CTC) capture and detection, liquid biopsy, preimplantation testing and immune sequencing.

The market for single cell analysis technologies is analyzed in depth. The market is analyzed by end user, application field, product type, omics method used, cell type, clinical indication and geography.

Specific geographic markets are discussed, including North America, Europe, Asia-Pacific and the rest of the world.

Market data covers the years 2015, 2016, 2017 (estimated) and 2022 (forecast).

More than 90 companies in the single cell analysis industry are profiled in this report.

BCC Research provides a summary of the main industry acquisitions and strategic alliances from Jan. 2016 through Sept. 2017, including key alliance trends.

Report Includes:

- 71 tables
- An overview of the global markets and emerging technologies for single-cell genomics and proteomics
- Analyses of global market trends, with data from 2016, estimates for 2017, and projections of compound annual growth rates (CAGRs) through 2022
- Cell isolation technologies, including flow cytometry, laser capture microscopy, and micromanipulation
- Sample preparation technologies, including microfluidics, whole genome amplification/pre-amplification
- Analyses of next-generation sequencing, qPCR/PCR, microarrays, mass spectrometry, and microfluidics
- End-use industry coverage, including research, drug discovery and development, diagnostics, and applied
- Evaluation of the market's dynamics, including growth drivers, restraints, and opportunities
- Profiles of major players in the industry including 1 Cellbio, 10x Genomics Inc., Angle PLC, Aviva Biosciences, Boreal Genomics, Dolomite Bio and Hifibio"


Chapter 1 Introduction
Study Goals and Objectives
Reasons for Doing This Study
Scope of Report
Methodology
Information Sources
Geographic Breakdown
Analyst's Credentials
Related BCC Research Reports
Chapter 2 Summary and Highlights
Chapter 3 Overview
Introduction
Report Scope
Workflow
Technology Challenges
Markets
Growth Driving Forces
Key Trends
Industry
Chapter 4 Technology Background
What Makes Single-cell Analysis Unique?
Single-cell Omics
Single-cell Analysis Workflow
Cell Isolation Technologies
Sample Preparation Technologies
Analysis Technologies
DNA Encoded Libraries in Single Cell Analysis
Genome-edited Single Cell Technologies
High-throughput Single-cell Technologies
Single-cell Multi-omics Technology
Single-cell RNA-Seq Technologies
Single-cell Technology Challenges
Chapter 5 Single-cell Initiatives and Cores
4D Nucleome Project
Allen Human Brain Atlases
Allen Institute of Cell Science
Brain Initiative
Centre of Single-cell Biology
Follow That Cell Challenge
Human Cell Atlas Initiative
Microbial Dark Matter Project
Next-Generation Single-cell Analysis Program
Single-cell Analysis Program
Single-cell Analysis Program-Transcriptome Project
Single-cell Proteomics and Lipidomics Project
Single-cell Surveyor Society
Cambridge Single-cell Analysis Core Facility
Harvard Medical School Single-cell Core
Mayo Medical Genome Facility
National Center for Single-cell Biology
Single-cell Analysis Core
UC San Francisco Single-cell Analysis Center
Chapter 6 Single-cell Applications
Introduction
Basic Cell Biology
Immunology
Microbiology
Neurology
Oncology
Stem Cell Biology
Liquid Biopsy
Preimplantation Genetic Diagnosis and Screening
Human Identification
Agriculture
Chapter 7 Single-cell Industry
Introduction
Target Enrichment Industry
Droplet Digital PCR Industry
Single-cell DNA Polymerase Industry
DNA Amplification Industry
NGS Instrument Industry
Single-cell Proteomics Industry
CTC Capture and Detection Industry
Liquid Biopsy Industry
Preimplantation Testing Industry
Immune Sequencing Industry
Chapter 8 Acquisitions and Strategic Alliances
Acquisitions
Strategic Alliances
Chapter 9 Single-cell Omics Markets
Growth Driving Forces
Single-cell Omics Market
Single-cell omics Diagnostics Markets
Breast Cancer
Colorectal Cancer
Ovarian Cancer
Lung Cancer
Multiple Myeloma
Prostate Cancer
Research Market
Drug Discovery and Development Market
Applied Market
Single-cell Omics Geographical Market
Chapter 10 Patent Review
Chapter 11 Company Profiles
1 CELLBIO
10X GENOMICS INC.
ACCELERATE DIAGNOSTICS INC.
AGILENT TECHNOLOGIES INC.
AMBRY GENETICS
ANGLE PLC
APOCELL INC.
ASURAGEN INC.
ATRECA INC.
AVIVA BIOSCIENCES
BECTON, DICKINSON AND CO.
BERRY GENOMICS CO. LTD.
BGI SHENZHEN
BIOARRAY S.L.
BIOCEPT INC.
BIOFLUIDICA INC.
BIO-RAD LABORATORIES INC.
BIO-TECHNE LTD.
BOREAL GENOMICS
CELL MICROSYSTEMS INC.
CELSEE DIAGNOSTICS
CELLULAR RESEARCH INC.
CHRONIX BIOMEDICAL
CIRCULOMICS INC.
COOPER SURGICAL INC.
CYNVENIO BIOSYSTEMS INC.
CYTENA GMBH
CYTOLUMINA TECHNOLOGIES CORP. INC.
CYTOTRACK APS
DANAHER CORP.
DIAGNOLOGIX LLC
DNA ELECTRONICS LTD.
DOLOMITE BIO
ENGINE BIOSCIENCES PTE. LTD.
EPIC SCIENCES
EXOSOME DIAGNOSTICS INC.
FETOLUMINA TECHNOLOGIES CORP.
FLOWJO LLC
FLUIDIGM CORP
FLUXION BIOSCIENCES INC.
GE HEALTHCARE
GIGAGEN INC.
GILUPI GMBH
GOOD START GENETICS INC.
HIFIBIO
HTG MOLECULAR DIAGNOSTICS INC.
ILLUMINA INC.
INCELLDX INC.
ISOPLEXIS CORP.
KELLBENX INC.
LABORATORY CORP. OF AMERICA INC.
LGC BIOSEARCH TECHNOLOGIES
MENARINI SILICON BIOSYSTEMS
MERCK KGAA
MISSION BIO INC.
MUSE BIOTECHNOLOGY INC.
NAMOCELL INC.
NANOCELLECT BIOMEDICAL INC.
NANOSTRING TECHNOLOGIES INC.
NATERA INC.
NEW ONCOLOGY GMBH
NODALITY INC.
NUGEN TECHNOLOGIES INC.
OXFORD NANOPORE TECHNOLOGIES LTD.
PACIFIC BIOSCIENCES OF CALIFORNIA INC.
PERKINELMER INC.
QIAGEN NV
RARECELLS SAS
RARECYTE INC.
RAVATA SOLUTIONS
REPRODUCTIVE HEALTH SCIENCE PTY LTD.
RESOLUTION BIOSCIENCE INC.
ROCHE HOLDING AG
ROYAL PHILIPS
SCREENCELL
SENGENICS INTERNATIONAL PTE LTD.
SINGULOMICS CORP.
SOMAGENICS INC.
SPHERE FLUIDICS LTD.
STRATEC BIOMEDICAL AG
SWIFT BIOSCIENCES INC.
SYGNIS AG
SYSMEX CORP.
TAKARA BIO INC.
THERMO FISHER SCIENTIFIC INC.
THORNE DIAGNOSTICS INC.
TROVAGENE INC.
TUMORGEN MDX LLC
VITATEX INC.
YIKON GENOMICS CO. LTD.
List of Tables
Summary Table : Single-cell Omics Market, by End User, Through 2022
Table 1 : Key Single-cell Omics Market Segments Covered
Table 2 : Single Cell Analysis Workflow
Table 3 : Single-cell Omics Market, by Analyte Type, Through 2022
Table 4 : Single Cell Analysis Market Growth Driving Forces
Table 5 : Trends in Single-cell Analysis
Table 6 : Key Segments within the Single-cell Analysis Industry
Table 7 : Unique Technical Challenges of Single-cell Analysis
Table 8 : Single-cell Omics
Table 9 : Single-cell analysis Workflow
Table 10 : Cell Differentiators
Table 11 : Cell Isolation Technologies
Table 12 : Single Cell Sample Preparation Workflows
Table 13 : Molecular Analysis Technologies
Table 14 : Genome-editing Technologies
Table 15 : Comparison of Gene Editing Platforms
Table 16 : High-throughput Single-cell Technologies
Table 17 : Technical Strategies for Single-cell Multi-omics
Table 18 : Emerging Droplet-based Single-cell RNA-seq Technologies
Table 19 : Technical Challenges for Single-cell Analysis
Table 20 : Key Single-cell Research and Development Projects
Table 21 : Single-cell Core Research Facilities
Table 22 : Single-cell Analysis: Near- to Mid-term Applications
Table 23 : Key Objectives of Basic Single-cell Biology
Table 24 : Single-cell Analysis to Identify Cancer Driver Mutations
Table 25 : Stem Cells
Table 26 : Biomarkers in Liquid Biopsy
Table 27 : Factors in Tissue Biopsy
Table 28 : Preimplantation Genetic Diagnosis and Screening Applications
Table 29 : Key Segments Within the Single-cell omics Industry
Table 30 : Target Enrichment Industry
Table 31 : Advantages of Droplet Digital PCR for Single-cell analysis
Table 32 : Droplet Digital PCR Industry
Table 33 : Single-cell DNA Polymerase Industry
Table 34 : Single-cell Sequencing Workflow
Table 35 : Single-cell DNA Amplification Industry
Table 36 : Next Generation Sequencing Instrument Company Summary
Table 37 : Single-cell Proteomics Industry
Table 38 : CTC Capture and Detection Industry
Table 39 : Liquid Biopsy Industry Company Focus
Table 40 : Example of NGS-based Liquid Biopsy Market Differentiation
Table 41 : Preimplantation Diagnostics Platforms
Table 42 : Preimplantation Genetic Testing Industry
Table 43 : Immune System Profiling Industry
Table 44 : Single-cell Industry Acquisitions, Jan. 2016 Through Sept. 2017
Table 45 : Single-cell Industry Strategic Alliances, Jan. 2016 Through Sept. 2017
Table 46 : Single-cell Omics Market Growth Driving Forces
Table 47 : Single-cell Analysis Market, by End-use Industry, Through 2022
Table 48 : Single-cell Omics Market, by Product Type, Through 2022
Table 49 : Single-cell Omics Market, by Field, Through 2022
Table 50 : Single-cell Omics Market, by Analysis Type, Through 2022
Table 51 : Single-cell Omics Market, by Cell Type, Through 2022
Table 52 : Single-cell Diagnostics Market, by Indication, Through 2022
Table 53 : Single-cell Omics Diagnostics Market, by Analysis Type, Through 2022
Table 54 : CTC Market Landscape
Table 55 : Omics-based CTC Cancer Focus
Table 56 : CTC Diagnostics Market, by Indication, Through 2022
Table 57 : Five-year Survival Rate for Ovarian Cancer
Table 58 : Single-cell Omics Research Market, by Field, Through 2022
Table 59 : Single-cell Omics Research Market, by Analysis Type, Through 2022
Table 60 : Single-cell Omics Research Market, by Cell Type, Through 2022
Table 61 : Single-cell Omics Drug Discovery and Development Market, by Field, Through 2022
Table 62 : Single-cell Omics Drug Discovery and Development Market, by Analysis Type, Through 2022
Table 63 : Single-cell Omics Drug Discovery and Development Market, by Cell Type, Through 2022
Table 64 : Single-cell Omics Applied Market, by Application, Through 2022
Table 65 : Single-cell Omics Applied Market, by Analysis Type, Through 2022
Table 66 : Single-cell Omics Applied Market, by Cell Type, Through 2022
Table 67 : Single-cell Omics Market, by Region, Through 2022
Table 68 : Patents on Single-cell Technologies, by Region, 2007 Through Oct. 2017
Table 69 : Patents on CTC-related Technologies, by Region, 2007 Through Oct. 2017
Table 70 : Patents on Microfluidics-related Single Cell Technologies, 2007 Through Oct. 2017
Table 71 : Patents on High-Throughput-related Single Cell Technologies, 2007 Through Oct. 2017
List of Figures
Summary Figure : Single-cell Omics Market, by End User, 2015-2022

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