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Radiotherapy: Technologies and Global Markets

Radiotherapy: Technologies and Global Markets

The radiation therapy market totaled $5.4 billion in 2013 and $5.8 billion in 2014. The market is expected to reach $8.1 billion in 2019, a compound annual growth rate(CAGR) of 6.7%.

This report provides:

An overview of the global market for radiotherapy and related technologies and applications

Analyses of market trends, with data from 2013 and 2014, and projections of CAGRs through 2019

Discussion of major factors driving the growth for nuclear medicine including neurological diseases such as Alzheimer's disease, Parkinson's disease, and dementia, and an overall increase in awareness about nuclear medicine

Detailed information conerning major challenges the market faces including the harmful effects of radiation, the tight required regulation of radioisotopes, and a lack of supply of radioisotopes

Analysis of the diagnostic applications for radiotherapy such as Single Photon Emission Computed Tomography (SPECT) and Positron Emission Tomography (PET)

Comprehensive company profiles of major players in the industry.


SCOPE OF REPORT

This research report categorizes the radiation therapy market into three types of radiation therapy, which are External Beam radiation therapy, Internal Radiation therapy/Brachytherapy and Systemic Radiation therapy. External Radiotherapy is future divided into Gamma Knife, LINACS.( 3D-CRT, IMRT,IGRT), Proton Therapy System (Proton-based and Carbon-based). Internal Radiotherapy is divided into three types: Low dose Brachytherapy (Seeds: I-125, Pd-103, Applicators and Afterloaders), High dose brachytherapy (Seeds: Ir-192, Applicators and Afterloaders) and Electronic Brachytherapy. Systemic radiation therapy is bifurcated into two segments: Alpha emitter (Radium (Ra-233) and Beta emitters (Iodine (I-131), Rhenium (Re-186), Samarium (Sm-153), Yttrium-90 (Y-90), Lutetium-177 (LU-177).

Radiation therapy has also been studied based on the various applications into: External radiation therapy applications: Prostate Cancer, Breast Cancer, Lung Cancer, Head & Neck Cancer; Internal Radiation therapy applications: Prostate Cancer, Gynecological Cancer, Breast Cancer, Cervical Cancer; and Systemic Radiation therapy applications: Hyperthyroidism, Bone Metastasis, Lymphoma, Endocrine tumor. Also, the Radiation therapy market by geography: U.S., Europe, Asia, Rest of the World.

CHAPTER 1 INTRODUCTION
STUDY GOALS AND OBJECTIVES
REASONS FOR DOING THE STUDY
SCOPE OF REPORT
INTENDED AUDIENCE
RESEARCH METHODOLOGY
ANALYST'S CREDENTIALS
RELATED BCC RESEARCH REPORTS
BCC RESEARCH WEBSITE
DISCLAIMER
CHAPTER 2 EXECUTIVE SUMMARY
SUMMARY TABLE RADIATION THERAPY MARKET BY TYPE, THROUGH 2019 ($MILLIONS)
SUMMARY FIGURE RADIATION THERAPY MARKET BY REGION, THROUGH 2019 ($ MILLIONS)
CHAPTER 3 MARKET OVERVIEW
INTRODUCTION
INTRODUCTION TO CANCER
BENIGN TUMORS
MALIGNANT TUMORS
Malignant Tumor Categories
Carcinomas
Sarcomas
OTHER TYPES OF CANCER
TABLE 1 CHARACTERISTICS OF BENIGN AND MALIGNANT TUMORS
CAUSES OF CANCER
Internal Factors
External Factors
CANCER PROTECTIVE FACTORS AND RISK FACTORS
TABLE 2 THE IMPACT OF CANCER PROTECTIVE FACTORS AND CANCER
RISK FACTORS ON VARIOUS TYPES OF CANCERS
INTRODUCTION TO RADIATION
FIGURE 1 TYPES OF RADIATION
NON-IONIZING RADIATION
IONIZING RADIATION
PARTICLE RADIATION
Electron Beams
Proton Beams
Neutron Beams
Carbon Ions
Alpha and Beta Particles
Photon Radiations
Gamma Rays
X-rays
HISTORY OF RADIATION THERAPY
The Discovery Period
Megavoltage Era (1946-1996)
Computer-assisted ERA (1996-2013)
MECHANISM OF ACTION
CELL GROWTH CYCLE
FIGURE 2 CELL GROWTH CYCLE
TABLE 3 STEPS INVOLVED IN RADIATION THERAPY
RISK MANAGEMENT AND QUALITY ASSURANCE IN RADIATION THERAPY
RADIATION THERAPY MARKET SEGMENTATION
FIGURE 3 RADIATION THERAPY MARKET SEGMENTATION
DRIVERS, RESTRAINTS, OPPORTUNITIES AND TRENDS
FIGURE 4 DRIVERS, RESTRAINTS, OPPORTUNITIES AND TRENDS IN THE RADIATION THERAPY MARKET
DRIVERS
Increasing Incidences of Cancer
High Incidence of Cancer in Aging Population
FIGURE 5 GLOBAL AGING POPULATION (MILLIONS)
FIGURE 6 FACTORS RELATED TO AGING AND THE PROMOTION OF CANCER
High Efficiency of Radiotherapy
Palliative Radiation Therapy
Government Funding
Advancement in Technology
Reimbursement Boosting Market Growth
RESTRAINTS
Capital Intensive
Lack of Trained Professionals
Limited Effectiveness against Metastatic Cancer
Side Effects Associated with Radiation Therapy
OPPORTUNITY
Developing Countries
Personalized Treatment
TRENDS
VMAT
Proton Therapy
Carbon Ions
THREAT
Recession Can Restrict the Growth of Radiation Therapy Market
MARKET SHARE ANALYSIS
FIGURE 7 MARKET SHARE ANALYSIS OF THE RADIATION THERAPY MARKET, 2013 (%)
VARIOUS CANCER TREATMENTS
TABLE 4 ADVANTAGES AND DISADVANTAGES OF VARIOUS CANCER
TREATMENTS
STEREOTACTIC RADIOSURGERY (SRS) AND FRACTIONATED STEREOTACTIC
RADIATION THERAPY
CHAPTER 4 RADIATION THERAPY MARKET BY PRODUCTS
TABLE 5 COMPARISON OF EXTERNAL BEAM RADIATION THERAPY AND BRACHYTHERAPY
EXTERNAL BEAM RADIATION THERAPY
TREATMENT PLANNING FOR EXTERNAL BEAM RADIATION
Dosing and Treatment with External Beam Radiation
TABLE 6 EXTERNAL BEAM RADIATION THERAPY MARKET BY TYPE THROUGH 2019 ($ MILLIONS)
TABLE 7 EXTERNAL BEAM RADIATION THERAPY BY REGION, THROUGH 2019 ($ MILLIONS)
GAMMA KNIFE
MECHANISM OF ACTION
TABLE 8 GAMMA KNIFE MARKET BY REGION, THROUGH 2019 ($ MILLIONS)
LINEAR ACCELERATORS (LINACS)
Structure of Linear Accelerators
Electron Guns
The Buncher
The LINACS
Magnetrons
Klystrons
Beam Collimation and Monitoring
TABLE 9 ELECTRON EMITTING HIGH ENERGY LINEAR ACCELERATORS
BY REGION, THROUGH 2019 ($ MILLIONS)
TABLE 10 LINACS MARKET BY TECHNIQUES, THROUGH 2019 ($ MILLIONS)
TYPES OF LINACS BY TECHNIQUES
Three-dimensional Conformal Radiation Therapy (3D-CRT)
TABLE 11 THREE-DIMENSIONAL CONFORMAL RADIATION THERAPY BY REGION, THROUGH 2019 ($ MILLIONS)
Intensity-modulated Radiation Therapy (IMRT)
High Cost Restricts the Use
TABLE 12 INTENSITY-MODULATED RADIATION THERAPY MARKET BY REGION, THROUGH 2019 ($ MILLIONS)
Image-guided Radiation Therapy (IGRT)
TABLE 13 IMAGE-GUIDED RADIATION THERAPY MARKET BY REGION, THROUGH 2019 ($ MILLIONS)
Other LINACS
TABLE 14 OTHER LINACS MARKET BY REGION, THROUGH 2019 ($ MILLIONS)
PARTICLE THERAPY
TABLE 15 COMPARISON OF PROTON BEAM THERAPY AND CARBON ION THERAPY
TABLE 16 PARTICLE THERAPY SYSTEM BY TYPE, THROUGH 2019 ($ MILLIONS)
TABLE 17 PARTICLE THERAPY SYSTEM MARKET BY REGION, THROUGH 2019 ($ MILLIONS)
TABLE 18 PROTON SYSTEMS MARKET BY REGION, THROUGH 2019 ($ MILLIONS)
Carbon Ions
TABLE 19 CARBON ION THERAPY MARKET BY REGION, THROUGH 2019 ($ MILLIONS)
BRACHYTHERAPY
TABLE 20 COMMONLY USED RADIONUCLIDES (RADIATION SOURCES) FOR BRACHYTHERAPY
TABLE 21 ADVANTAGES AND DISADVANTAGES OF BRACHYTHERAPY
TABLE 22 VARIOUS TYPES OF BRACHYTHERAPY IMPLANTS
TABLE 23 BRACHYTHERAPY TREATMENT DURATION
TABLE 24 BRACHYTHERAPY TREATMENT DOSE RATE
TABLE 25 BRACHYTHERAPY TREATMENT SOURCE LOADING
PDR BRACHYTHERAPY
TABLE 26 COMPARISON OF LOW DOSE AND HIGH DOSE RADIATION
THERAPY
TABLE 27 GLOBAL BRACHYTHERAPY MARKET BY PRODUCT, THROUGH 2019 ($ MILLIONS)
TABLE 28 GLOBAL BRACHYTHERAPY MARKET BY REGION, THROUGH 2019 ($ MILLIONS)
LDR BRACHYTHERAPY MARKET
TABLE 29 GLOBAL LDR BRACHYTHERAPY MARKET BY PRODUCT, THROUGH 2019 ($ MILLIONS)
TABLE 30 GLOBAL LDR BRACHYTHERAPY MARKET BY REGION, THROUGH 2019 ($ MILLIONS)
LDR Brachytherapy Seeds
TABLE 31 MARKET FOR LDR BRACHYTHERAPY SEEDS BY REGION, THROUGH 2019 ($ MILLIONS)
Brachytherapy Seeds Market by Type of Radioisotope
TABLE 32 GLOBAL BRACHYTHERAPY SEEDS MARKET BY TYPE, THROUGH 2019 ($ MILLIONS)
Iodine-125
TABLE 33 GLOBAL I-125 SEEDS MARKET BY REGION, THROUGH 2019 ($ MILLIONS)
Palladium-103
TABLE 34 GLOBAL PD-103 SEEDS MARKET BY REGION, THROUGH 2019 ($ MILLIONS)
Other Seeds
TABLE 35 GLOBAL OTHER LDR BRACHYTHERAPY SEEDS MARKET BY REGION, THROUGH 2019 ($ MILLIONS)
TABLE 36 LDR AFTERLOADER AND APPLICATOR MARKET BY GEOGRAPHY THROUGH 2019 ($ MILLIONS)
HDR BRACHYTHERAPY MARKET
TABLE 37 HDR BRACHYTHERAPY MARKET BY PRODUCT, THROUGH 2019 ($ MILLIONS)
TABLE 38 HDR BRACHYTHERAPY MARKET BY REGION, THROUGH 2019 ($ MILLIONS)
HDR Brachytherapy Seed Market
TABLE 39 HDR SEEDS MARKET BY PRODUCT, THROUGH 2019 ($ MILLIONS)
TABLE 40 HDR SEEDS MARKET BY REGION, THROUGH 2019 ($ MILLIONS)
Iridium-192 seeds
TABLE 41 IR-192 SEEDS MARKET BY REGION, THROUGH 2019 ($ MILLIONS)
Other HDR Seeds
TABLE 42 OTHER HDR SEEDS MARKET BY REGION, THROUGH 2019 ($ MILLIONS)
TABLE 43 HDR AFTERLOADER AND APPLICATOR MARKET BY REGION, THROUGH 2019 ($ MILLIONS)
ELECTRONIC BRACHYTHERAPY
TABLE 44 COMPARISON BETWEEN RADIONUCLIDES AND ELECTRONIC
BRACHYTHERAPY
TABLE 45 GLOBAL ELECTRONIC BRACHYTHERAPY MARKET BY GEOGRAPHY THROUGH 2019 ($ MILLIONS)
THERAPEUTIC RADIOPHARMACEUTICALS BY TYPE
TABLE 46 ADVANTAGES AND DISADVANTAGES OF RADIOPHARMACEUTICALS
COMPARISON BETWEEN ALPHA AND BETA EMITTERS
TABLE 47 COMPARISON OF ALPHA AND BETA PARTICLES
SHORTAGE OF RADIONUCLIDES
CUMBERSOME REGULATORY REQUIREMENTS
TABLE 48 MARKET FOR THERAPEUTIC RADIOPHARMACEUTICALS BY TYPE, THROUGH 2019 ($ MILLIONS)
TABLE 49 SYSTEMIC RADIATION THERAPY BY REGION, THROUGH 2019 ($ MILLIONS)
ALPHA EMITTERS
TABLE 50 GLOBAL ALPHA EMITTER MARKET BY TYPE, THROUGH 2019 ($ MILLIONS)
TABLE 51 GLOBAL ALPHA EMITTER MARKET BY REGION, THROUGH 2019 ($ MILLIONS)
TABLE 52 EXAMPLES OF ALPHA EMITTERS
TABLE 53 ADVANTAGES AND DISADVANTAGES OF ALPHA EMITTERS
Radium-223
Mechanism of Action
BETA EMITTERS
TABLE 54 GLOBAL BETA EMITTERS MARKET BY TYPE, THROUGH 2019 ($ MILLIONS)
TABLE 55 ADVANTAGES AND DISADVANTAGES OF BETA EMITTERS
TABLE 56 MARKET FOR BETA EMITTERS BY REGION, THROUGH 2019 ($ MILLIONS)
Iodine-131
TABLE 57 GLOBAL IODINE-131 MARKET BY REGION, THROUGH 2019 ($ MILLIONS)
Rhenium (Re-186)
TABLE 58 GLOBAL RHENIUM-186 MARKET BY REGION, THROUGH 2019 ($ MILLIONS)
Samarium (Sm-153)
TABLE 59 GLOBAL SAMARIUM-153 MARKET BY REGION, THROUGH 2019 ($ MILLIONS)
Yttrium-90 (Y-90)
TABLE 60 GLOBAL YTTRIUM-90 MARKET BY REGION, THROUGH 2019 ($ MILLIONS)
Lutetium-177 (Lu-177)
TABLE 61 GLOBAL LUTETIUM-177 MARKET BY REGION, THROUGH 2019 ($ MILLIONS)
Others
TABLE 62 GLOBAL OTHER BETA EMITTERS MARKET BY REGION, THROUGH 2019 ($ MILLIONS)
ROUTE OF ADMINISTRATION
Introduction
Intravenous Administration
Inhalation Administration
Peroral Administration
Other Routes of Administration
TABLE 63 OTHER ROUTES OF ADMINISTRATION
PIPELINE PRODUCTS
TABLE 64 PIPELINE PRODUCTS IN RADIOPHARMACEUTICALS
CHAPTER 5 RADIATION THERAPY MARKET BY APPLICATION
EXTERNAL BEAM RADIATION THERAPY MARKET
TABLE 65 EXTERNAL BEAM RADIATION THERAPY BY APPLICATION, THROUGH 2019 ($ MILLIONS)
PROSTATE CANCER
Life Expectancy
Overall Health Status
Tumor Characteristics
Stage I Prostate Cancer
Stage II Prostate Cancer
Stage III Prostate Cancer
Stage IV Prostate Cancer
Personal Preferences
Advantages of EBRT in Treating Prostate Cancer
Side Effects
Disadvantages
BREAST CANCER
LUNG CANCER
Types of Lung Cancer
Non-Small Cell Lung Cancer
Small Cell Lung Cancer
Lung Carcinoid Tumor
HEAD AND NECK CANCER
Conformal Radiation Therapy (CRT)
OTHER CANCERS
INTERNAL RADIATION THERAPY MARKET BY APPLICATION
TABLE 66 INTERNAL BEAM RADIATION THERAPY BY APPLICATION THROUGH 2019 ($ MILLIONS)
PROSTATE CANCER
HEAD AND NECK CANCER
GYNECOLOGICAL CANCER
Vaginal Cancer
BREAST CANCER
CERVICAL CANCER
SYSTEMIC RADIATION THERAPY
TABLE 67 SYSTEMIC RADIATION THERAPY BY APPLICATION, THROUGH 2019 ($ MILLIONS)
HYPERTHYROIDISM
BONE METASTASES
LYMPHOMA
ENDOCRINE TUMORS
CHAPTER 6 RADIATION THERAPY MARKET BY GEOGRAPHY
UNITED STATES
TABLE 68 U.S. RADIATION THERAPY MARKET BY TYPE, THROUGH 2019 ($ MILLIONS)
TABLE 69 U.S. INSTALLED BASE AND AGE
TABLE 70 NEW CANCER CASES AND ESTIMATED DEATHS IN THE YEAR 2014
TABLE 71 AGING U.S. POPULATION, 2000-2050
EUROPE
TABLE 72 EUROPEAN RADIATION THERAPY MARKET BY TYPE THROUGH 2019 ($ MILLIONS)
ASIA
TABLE 73 ASIAN RADIATION THERAPY MARKET BY TYPE, THROUGH 2019 ($MILLIONS)
JAPAN
TABLE 74 COMPARISON OF INDIAN AND CHINESE RADIATION THERAPY
MARKETS
CHINA
INDIA
REST OF THE WORLD
TABLE 75 REST OF THE WORLD RADIATION THERAPY MARKET BY TYPE, THROUGH 2019 ($ MILLIONS)
LATIN AMERICA
MIDDLE EAST
AFRICA
CHAPTER 7 COMPANY PROFILES
ACCURAY INCORPORATED
FINANCIALS
TABLE 76 ACCURAY REVENUES AND R &D EXPENDITURES, 2011-2013 ($ MILLIONS/%)
PRODUCTS
TABLE 77 ACCURAY PRODUCTS
RECENT NEWS
TABLE 78 ACCURAY RECENT NEWS
ACTINIUM PHARMACEUTICALS INC.
AUSTRALIAN NUCLEAR ASSOCIATION AND TECHNOLOGY ORGANIZATION (ANSTO)
C. R. BARD INC.
FINANCIALS
TABLE 79 C.R. BARD REVENUES AND R &D EXPENDITURES, 2011-2013 ($ MILLIONS)
PRODUCTS
ECKERT & ZIEGLER BEBIG S.A
FINANCIALS
TABLE 80 ECKERT & ZIEGLER REVENUES AND R &D EXPENDITURES, 2011-2013 ($ MILLIONS/%)
PRODUCTS
RECENT NEWS
TABLE 81 ECKERT & ZIEGLER RECENT NEWS
ELEKTA
FINANCIALS
TABLE 82 ELEKTA REVENUES AND R &D EXPENDITURES, 2011-2013 ($ MILLIONS/%)
PRODUCTS
RECENT NEWS
TABLE 83 ELEKTA RECENT NEWS
GE HEALTHCARE
GE HEALTHCARE LIFE SCIENCES
PRODUCTS
IBA MOLECULAR
NORDION INC.
NTP RADIOISOTOPES (PTY) LTD.
SIEMENS HEALTHCARE
FINANCIALS
TABLE 84 SIEMENS REVENUES AND R &D EXPENDITURES, 2011-2013 ($ MILLIONS/%)
PRODUCTS
RECENT NEWS
TABLE 85 SIEMENS RECENT NEWS
VARIAN MEDICAL SYSTEMS
FINANCIALS
TABLE 86 VARIAN REVENUES AND R &D EXPENDITURES, 2011-2013 ($ MILLIONS/%)
PRODUCTS
RECENT NEWS
TABLE 87 VARIAN RECENT NEWS
CHAPTER 8 APPENDIX A LIST OF HUMAN OF CARCINOGENIC AGENTS
BY TYPE OF CANCER
TABLE 88 LIST OF CARCINOGENIC AGENTS
CHAPTER 9 APPENDIX B LIST OF ACRONYMS

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