Market Research Logo

Glycobiology: Global Markets for Diagnostics and Therapeutics

A description is not currently available for this report.

CHAPTER 1 INTRODUCTION
STUDY GOALS AND OBJECTIVES
REASONS FOR DOING THIS STUDY
SCOPE AND FORMAT
METHODOLOGY AND INFORMATION SOURCES
INTENDED AUDIENCE
ANALYST'S CREDENTIALS
RELATED BCC RESEARCH REPORTS
BCC RESEARCH WEBSITE
DISCLAIMER
CHAPTER 2 SUMMARY
SUMMARY TABLE GLOBAL MARKET FOR GLYCOBIOLOGY, BY SEGMENT, THROUGH 2021 ($ MILLIONS)
SUMMARY FIGURE GLOBAL MARKET FOR GLYCOBIOLOGY, BY SEGMENT, 2014-2021 ($ MILLIONS)
CHAPTER 3 INTRODUCTION TO GLYCOBIOLOGY MARKET
OVERVIEW
GLYCOBIOLOGY DEFINITION
TABLE 1 CLASSIFICATION OF CARBOHYDRATES
SIGNIFICANCE OF GLYCAN
FIGURE 1 SCHEMATIC PRESENTATION OF O- AND N-LINKED GLYCANS ON PROTEIN RECEPTOR
N-Linked Glycans
O-Linked Glycans
Glycosaminoglycans
Glycolipids
Glycosylphosphatidylinositol Anchors
FUNCTION OF GLYCANS AND THEIR BIOLOGICAL SIGNIFICANCE
Structural Role of Glycans
Glycans as Specific Ligands for Cell-Cell Interactions
Glycans as Specific Ligands for Cell-Microbe Interactions
TABLE 2 EXAMPLES OF GLYCOSYLATION DEFICIENCY AND THEIR PATHOLOGICAL EFFECT
RESEARCH TOOLS FOR GLYCOBIOLOGY STUDIES
TABLE 3 EXPERIMENTAL APPROACHES TO STUDYING GLYCANS
Glycan-Binding Proteins or Antibodies
Metabolic Inhibition or Alteration of Glycosylation
TABLE 4 EXAMPLES OF INHIBITORS/MODULATORS USED IN GLYCOBIOLOGY RESEARCH
Finding Natural Glycan Ligands for Specific Receptors
Finding Receptors for Specific Glycans
Competition Studies Using Soluble Glycans or Structural Mimics
Eliminating Specific Glycan Structures by Glycosidases
Studying Natural or Genetically Engineered Glycan Mutants
Studying Natural or Genetically Engineered Glycan Receptor Mutants
STRUCTURAL ANALYSIS OF GLYCANS
TABLE 5 SEPARATION AND IDENTIFICATION TECHNIQUES USED FOR GLYCAN ANALYSIS
Detection of Glycans
Release, Profiling and Fractionation of Glycans
GLYCOMICS AS PART OF GLYCOBIOLOGY RESEARCH
Mass Spectrometry
Lectin and Antibody Arrays
Cell and Tissue Analysis Using Lectins and Antibodies
Imaging the Glycome by Metabolic and Covalent Labeling
CHEMICAL AND ENZYMATIC SYNTHESIS OF GLYCANS AND GLYCOCONJUGATES
BIOINFORMATICS AND DATABASE RESOURCES FOR GLYCOBIOLOGY
RESEARCH
TABLE 6 BIOINFORMATICS AND DATABASE RESOURCES FOR GLYCOBIOLOGY RESEARCH
CHAPTER 4 GLYCOBIOLOGY THERAPEUTICS MARKET
OVERVIEW
SUBCATEGORIES OF GLYCOBIOLOGY THERAPEUTICS
GLYCANS AS COMPONENTS OF SMALL-MOLECULE DRUGS
TABLE 7 GLOBAL MARKET FOR SYSTEMIC ANTIBIOTICS, THROUGH 2020 ($ BILLIONS)
SMALL-MOLECULE INHIBITORS OF INFLUENZA VIRUS NEURAMINIDASE
TABLE 8 GLOBAL SALES OF RELENZA AND TAMIFLU, 2014 AND 2015 ($ MILLIONS)
THERAPEUTIC GLYCOPROTEINS
TABLE 9 GLOBAL SALES OF ARANESP, 2014 AND 2015 ($ MILLIONS)
GLYCAN THERAPEUTIC APPROACHES TO METABOLIC DISEASES
Salvage versus De Novo Synthesis
Special Diets
Substrate Reduction Therapy
TABLE 10 GLOBAL SALES OF ZAVESCA, 2014 AND 2015 ($ MILLIONS)
Lysosomal Enzyme Replacement Therapy
TABLE 11 GLOBAL SALES OF CEREZYME, NAGLAZYME AND ALDURAZYME, 2014 THROUGH MARCH 2016 ($ MILLIONS)
Chaperone Therapy
THERAPEUTIC APPLICATIONS OF GLYCOSAMINOGLYCANS
TABLE 12 GLOBAL SALES OF LOVENOX AND FRAGMIN, 2014 AND 2015 ($ MILLIONS)
CARBOHYDRATE-BASED VACCINES AND GLYCANS AS VACCINE
COMPONENTS
TABLE 13 GLOBAL SALES OF PREVNAR 13, 2014 AND 2015 ($ MILLIONS)
BLOCKING GLYCAN RECOGNITION IN DISEASES
TRANSFUSION AND TRANSPLANTATION REJECTION BY ANTIGLYCAN
ANTIBODIES
TABLE 14 EXAMPLES OF APPROVED GLYCOBIOLOGY-RELATED
TREATMENTS AND CARBOHYDRATE-BASED DRUGS
TABLE 15 SALES OF GLUCOBAY, 2014 AND 2015 ($ MILLIONS)
GLYCOBIOLOGY THERAPEUTICS IN DEVELOPMENT
TABLE 16 EXAMPLES OF GLYCOBIOLOGY-RELATED TREATMENTS AND CARBOHYDRATE-BASED DRUGS IN DEVELOPMENT
Alectos Therapeutics
Amicus Therapeutics
Endotis Pharma
Galectin Therapeutics
Glixis Therapeutics
Glycan Biosciences
Glycan Therapeutics
GlycoGenesys
Glycomantra
Glycomar
GlycoMimetics
Glycomine
GlycoMira Therapeutics
Glycotope GmbH
Malcisbo AG
ProtAffin Biotechnologie AG
Siamab Therapeutics
VaxAlta
Vaxil Bio Therapeutics
EVALUATION OF GLYCOBIOLOGY THERAPEUTICS MARKET
OVERVIEW
Carbohydrate-Based Drugs
TABLE 17 EXAMPLES OF APPROVED CARBOHYDRATE-BASED DRUGS
Glycosylated Small Molecules
Glycoproteins as Therapeutics
Glycan Therapeutic Approaches to Metabolic Diseases
Blocking Glycan Recognition in Diseases
Carbohydrate-based Vaccines and Glycans as Vaccine
TABLE 18 GLOBAL MARKET FOR GLYCOBIOLOGY THERAPEUTICS, THROUGH 2021 ($ BILLIONS)
FIGURE 2 GLOBAL MARKET FOR GLYCOBIOLOGY THERAPEUTICS, 2014-2021 ($ BILLIONS)
MARKET LANDSCAPE
TABLE 19 EXAMPLES OF CARBOHYDRATE-BASED DRUGS APPROVED AS CANCER ADJUVANTS IN COUNTRIES OUTSIDE THE U.S.
TABLE 20 GEOGRAPHICAL DISTRIBUTION OF GLYCOBIOLOGY THERAPEUTIC MARKET, 2016 (%)
MARKET TRENDS IN GLYCOBIOLOGY THERAPEUTICS
PROTEIN AND GLYCAN GLYCOENGINEERING TO ENHANCE EFFICACY AND THERAPEUTIC VALUE
ENGINEERING GLYCANS AND GLYCAN MIMICS AS THERAPEUTIC AGENTS
Glycan Small Molecule Drugs
Polyvalent Glycan Structures and Inhibitors
GLYCOBIOLOGY AND DRUG DELIVERY
TABLE 21 GLOBAL MARKET FOR DRUG DELIVERY, THROUGH 2020 ($ BILLIONS)
OLIGOSACCHARIDE LIBRARIES FOR DRUG DISCOVERY RESEARCH
GLYCONUTRIENTS AS THERAPEUTICS
Glucosamine and Chondroitin Sulfate
Xylitol and Sorbitol in Chewing Gum
Milk Oligosaccharides
Chitosan
TABLE 22 GLOBAL MARKET FOR NUTRACEUTICALS, THROUGH 2019 ($ BILLIONS)
CHAPTER 5 GLYCOBIOLOGY DIAGNOSTICS MARKET
OVERVIEW
GLYCOBIOMARKERS AND AUTOIMMUNITY
GLYCOBIOMARKERS IN INFLAMMATORY BOWEL DISEASE
AUTOANTIBODIES AGAINST NEURONAL GLYCANS IN CERTAIN
NEUROPATHIES
AUTOANTIBODIES AGAINST TN ANTIGEN IN TN-POLYAGGLUTININ
SYNDROME
GLYCOBIOLOGY MARKERS IN CARDIOVASCULAR DISEASES
ROLE OF GLYCANS IN THE HISTOPATHOLOGY OF ALZHEIMER'S DISEASE
GLYCOBIOMARKERS AND ASTHMA
GLYCOBIOMARKERS IN INFECTIOUS DISEASE TESTING
TABLE 23 EXAMPLES OF GLYCOBIOLOGY-BASED BIOMARKERS
MARKET POTENTIAL FOR GLYCOBIOLOGY-BASED BIOMARKERS AND DIAGNOSTIC TESTS
TABLE 24 CURRENT U.S. MARKET POTENTIAL FOR DIAGNOSTIC TESTS BASED ON GLYCOBIOLOGY BIOMARKERS (MILLIONS/$ MILLIONS)
GLYCOBIOLOGY-BASED CANCER BIOMARKERS AND DIAGNOSTIC
DEVELOPMENT
TABLE 25 EXAMPLE OF GLOBAL CANCER STATISTICS, 2012
TABLE 26 FDA-APPROVED CANCER BIOMARKERS CURRENTLY USED IN CLINICAL PRACTICE
a-Fetoprotein (AFP)
Prostate-Specific Antigen (PSA)
MUC16 (CA125)
Human Epididymis Protein 4 (HE4)
MUC1 (CA15-3/CA27.29)
Human Epidermal Growth Factor Receptor 2 (HER2)
Carcinoembryonic Antigen (CEA)
Carbohydrate Antigen (CA19-9)
Thyroglobulin (Tg)
Potential Novel Biomarkers in Cancer Diagnostics
TABLE 27 EXAMPLES OF POTENTIAL GLYCOPROTEIN CANCER
BIOMARKERS
Human Chorionic Gonadotropin (hCG)
Alpha-1-Antitrypsin (A1AT)
Fucosylated Haptoglobin (Fuc-Hpt)
YKL-40
Carbohydrates as Potential Serum Biomarkers
TABLE 28 EXAMPLES OF CLINICAL TRIALS USING BLOOD/PLASMA OR SERUM CARBOHYDRATE ANALYSIS TO DIAGNOSE AND MONITOR
CANCER
TABLE 29 GLOBAL MARKET FOR TECHNOLOGIES FOR CANCER PROFILING AND PATHWAYS, THROUGH 2018 ($ BILLIONS)
CURRENT GLYCOBIOLOGY-BASED DIAGNOSTICS ON THE MARKET GLUCOSE MONITORING FOR DIABETES
TABLE 30 GLOBAL MARKET FOR CONTINUOUS GLUCOSE MONITORING, THROUGH 2019 ($ MILLIONS)
GLYCOHEMOGLOBIN (HBA1C, A1C)
CARBOHYDRATE INTOLERANCE TEST
CARBOHYDRATE-DEFICIENT TRANSFERRIN (CDT)
TABLE 31 GLOBAL MARKET FOR DRUG TESTING, THROUGH 2019 ($ BILLIONS)
COMPANIES WITH GLYCOBIOLOGY DIAGNOSTIC PLATFORMS AND PRODUCTS IN DEVELOPMENT
TABLE 32 EXAMPLES OF COMPANIES WITH DIAGNOSTIC PRODUCTS IN DEVELOPMENT BASED ON GLYCOBIOLOGY RESEARCH
GENOS GLYKO
GLYCODIAG
GLYCOMARK
GLUCOSENSE DIAGNOSTICS
GLYCOSENSORS AND DIAGNOSTICS LLC
GLYCOTECHNICA LTD.
GLYCOTEST DIAGNOSTICS
SIGMA DIAGNOSTICS
MARKET FOR GLYCOBIOLOGY-BASED DIAGNOSTICS
TABLE 33 GLOBAL MARKET FOR CLINICAL BIOMARKERS USED IN METABOLOMICS, THROUGH 2020 ($ MILLIONS)
TABLE 34 GLOBAL MARKET FOR GLYCOBIOLOGY-BASED DIAGNOSTICS, THROUGH 2021 ($ BILLIONS)
FIGURE 3 GLOBAL MARKET FOR GLYCOBIOLOGY-BASED DIAGNOSTICS, 2014-2021 ($ BILLIONS)
CHAPTER 6 MARKET FOR TOOLS AND REAGENTS USED IN
GLYCOBIOLOGY RESEARCH AND DEVELOPMENT
OVERVIEW
ANALYTICAL AND CHROMATOGRAPHY TECHNIQUES
GLYCAN ARRAYS
LECTIN ARRAYS
GLYCOBIOLOGY KITS
REAGENTS FOR GLYCOBIOLOGY RESEARCH
CARBOHYDRATES: MONOSACCHARIDES, OLIGOSACCHARIDES AND OTHER
REAGENTS
TABLE 35 EXAMPLES OF SUPPLIERS OF GLYCOBIOLOGY REAGENTS
Agilent Technologies
AMSBIO
Biognosys
CEVEC Pharmaceuticals GmbH
GALAB Technologies
Genos Glyco
GlycoBac LLC
Glycobiotech GmbH
Glykos Analytics
GlycoScientific LLC
GlycoSeLect Ltd.
Glycoseparations
GlycoTech
GlycoThera
IsoSep
LC Scientific Inc.
Ludger
New England Biolabs (NEB)
Omicron Biochemicals Inc.
Plexera
Prozyme
RayBiotech
R&D Systems
Robotic Labware Designs
Savyon Diagnostics
S-BIO
Sciex
Sigma-Aldrich
Sussex Research
Thermo Fisher Scientific
Vector Laboratories
Waters Corp.
TABLE 36 PRICES FOR GLYCOBIOLOGY REAGENTS AND SERVICES ($)
TABLE 37 GLOBAL MARKET FOR RESEARCH ASSAYS USED IN METABOLOMICS, THROUGH 2020 ($ MILLIONS)
MARKET FOR TOOLS AND REAGENTS FOR GLYCOBIOLOGY R&D
TABLE 38 EXAMPLES OF ANNUAL REVENUES OF COMPANIES THAT OFFER GLYCOBIOLOGY RESEARCH TOOLS ($ MILLIONS)
TABLE 39 GLOBAL MARKET FOR REAGENTS AND TOOLS FOR GLYCOBIOLOGY RESEARCH AND DEVELOPMENT, THROUGH 2021 ($ MILLIONS)
FIGURE 4 GLOBAL MARKET FOR REAGENTS AND TOOLS FOR GLYCOBIOLOGY RESEARCH AND DEVELOPMENT, 2014-2021 ($ MILLIONS)
CHAPTER 7 PATENT ANALYSIS OF GLYCOBIOLOGY MARKET
OVERVIEW
TABLE 40 NUMBER OF U.S. PATENTS AND APPLICATIONS ON GLYCOBIOLOGY RESEARCH
TABLE 41 NUMBER OF U.S. PATENTS ON GLYCOBIOLOGY RESEARCH, 2012-2015
TABLE 42 EXAMPLES OF PATENTS FILED ON GLYCOBIOLOGY RESEARCH
TABLE 43 NUMBER OF PATENTS IN GLYCOBIOLOGY RESEARCH BY PATENT HOLDER, 2012-2015
CHAPTER 8 MARKET SUMMARY
TABLE 44 GLOBAL MARKET FOR GLYCOBIOLOGY BY SEGMENT, THROUGH 2021 ($ MILLIONS)
FIGURE 5 GLOBAL MARKET FOR GLYCOBIOLOGY BY SEGMENT, 2014-2021 ($ MILLIONS)
TABLE 45 EXAMPLES OF MAIN MARKET PARTICIPANTS IN GLYCOBIOLOGY
MARKET BY SEGMENT
CHAPTER 9 OVERVIEW OF SELECT COMPANIES IN THE GLYCOBIOLOGY
MARKET
BIOMARIN PHARMACEUTICAL INC.
GLYCOMIMETICS
GLYCAN BIOSCIENCES LLC
GLYCOSENSORS AND DIAGNOSTICS LLC
GLYCOTEST INC.
CHAPTER 10 DIRECTORY OF COMPANIES REFERRED TO IN THE REPORT
DIRECTORY OF COMPANIES

Download our eBook: How to Succeed Using Market Research

Learn how to effectively navigate the market research process to help guide your organization on the journey to success.

Download eBook

Share this report