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Bioinformatics: Technologies and Global Markets

CHAPTER 1 INTRODUCTION
STUDY GOALS AND OBJECTIVES
REASONS FOR DOING THE STUDY
SCOPE OF REPORT
INTENDED AUDIENCE
INFORMATION SOURCES
ANALYST'S CREDENTIALS
RELATED BCC RESEARCH REPORTS
BCC RESEARCH WEBSITE
DISCLAIMER
CHAPTER 2 EXECUTIVE SUMMARY
SUMMARY TABLE GLOBAL BIOINFORMATIC MARKET BY REGION, THROUGH 2019 ($ MILLIONS)
SUMMARY FIGURE GLOBAL BIOINFORMATIC MARKET BY REGION, 2013-2019 ($MILLIONS)
CHAPTER 3 BIG DATA: WHAT TO DO WITH IT?
GOAL OF BIOINFORMATICS
FIGURE 1 RELATIONSHIP OF BIOINFORMATICS WITH 'OMIC TECHNOLOGIES
BIOLOGICAL DATA SOURCES
BIOINFORMATICS IN SYSTEMS BIOLOGY
FIGURE 2 SCHEMATIC REPRESENTATION OF BIOLOGY SYSTEMS AND TRANSLATIONAL BIOINFORMATICS
PRECISION MEDICINE
FIGURE 3 PRINCIPLES OF PRECISION MEDICINE
BIOINFORMATICS IN DRUG DEVELOPMENT
FIGURE 4 APPLICATIONS OF BIOINFORMATICS ON DRUG DEVELOPMENT
CHEMINFORMATICS
NEXT-GENERATION SEQUENCING
METAGENOMICS
DATA MANAGEMENT SYSTEMS
MARKET TRENDS
TABLE 1 U.S. FOOD AND DRUG ADMINISTRATION AND EUROPEAN MEDICINES AGENCY DRUG APPROVALS, 2009-2014
PRECISION MEDICINE AND BIOMARKER IDENTIFICATION
CLOUD-BASED SOLUTIONS
SHIFT TOWARD VALUE-BASED CARE
MARKET CHALLENGES
DATA INTEGRATION
DATA RELIABILITY AND STANDARDIZATION
END-TO-END WORKFLOWS
CURRENT MARKET
MARKET BY REGION
TABLE 2 GLOBAL BIOINFORMATIC MARKET BY REGION, THROUGH 2019 ($ MILLIONS)
MARKET BY CATEGORY
PUBLIC FUNDING
TABLE 3 PUBLIC FUNDING PROGRAMS, 2005-2014
PRIVATE FUNDING
TABLE 4 GLOBAL BIOINFORMATIC MARKET BY CATEGORY, THROUGH 2019 ($ MILLIONS)
MARKET BY APPLICATION
TABLE 5 GLOBAL BIOINFORMATIC MARKET BY APPLICATION, THROUGH 2019 ($ MILLIONS)
CHAPTER 4 BIOINFORMATICS: DATA GENERATION AND DATA
MANAGEMENT
INFORMATION OVERLOAD
FIGURE 5 FOUR DIMENSIONS OF BIG DATA
DATA VOLUME
DATA VARIETY
DATA VELOCITY
DATA VERACITY
TECHNOLOGIES BEHIND BIG DATA GENERATION
GENOMIC ADVANCES
SEQUENCING GENOMICS
Metagenomics
Exponential Growth in Next-Generation Sequencing Software Tools
FUNCTIONAL GENOMICS
Functional Genomics in Drug Discovery
CRISPR Cas9 System
PROTEOMIC ADVANCES
QUALITATIVE PROTEOMICS
QUANTITATIVE PROTEOMICS
STRUCTURAL PROTEOMICS
Protein Structure Initiative
Structural Genomic Consortium
INTERACTION PROTEOMICS
Application in Drug Discovery
Bottom-Up versus Top-Down Proteomics
FIGURE 6 TOP-DOWN PROTEOMIC APPROACH
Emergence of Glycomics
Human Proteome Organization and the Human Proteome Project
Initiative
TRANSCRIPTOMIC ADVANCES
RNA Sequencing
Co-Expression and Single-Cell RNA-Seq
METABOLOMIC ADVANCES
TABLE 6 COMMERCIALLY AVAILABLE METABOLOMIC SOFTWARE
TABLE 7 OPEN-ACCESS TOOLS FOR COMPLEX LIQUID
CHROMATOGRAPHY-MASS SPECTROMETRY DATA
ANALYSIS
CHEMINFORMATIC ADVANCES
TABLE 8 CHEMINFORMATIC SOFTWARE SOLUTIONS FOR DRUG RESEARCH
AND DEVELOPMENT
EMERGING TECHNOLOGIES
METAGENOMIC ADVANCES
TABLE 9 BIOINFORMATIC TOOLS FOR METAGENOMIC STUDIES
EPIGENOMIC ADVANCES
PHARMACOGENOMIC ADVANCES
PHARMACOGENOMICS AND PRECISION MEDICINE
VALUE-BASED DECISIONS
PHARMACOGENOMICS AND RESEARCH AND DEVELOPMENT
TABLE 10 BIOINFORMATIC TOOLS FOR PHARMACOGENOMIC STUDIES
INTERNATIONAL SERIOUS ADVERSE EVENTS CONSORTIUM
PHARMACOGENOMIC SOFTWARE
TABLE 11 BIOINFORMATIC TOOLS FOR PHARMACOGENOMIC SOFTWARE
TOXICOGENOMIC ADVANCES
TOXCAST COMPUTATIONAL TOXICOLOGY RESEARCH PROGRAM
CUSTOMIZED TOXICOGENOMIC PLATFORMS
DATABASE MANAGEMENT SERVICES
TABLE 12 ARCHIVAL DATABASES
TABLE 13 CURATIVE DATABASES
TABLE 14 COMMERCIALLY AVAILABLE DATABASES
MARKET DYNAMICS
CHAPTER 5 BIOINFORMATICS: DATA ANALYSIS AND SOFTWARE
INTRODUCTION
DATA ANALYSIS SOFTWARE
FIGURE 7 EUROPEAN BIOINFORMATIC INSTITUTE SOFTWARE SOLUTIONS
TABLE 15 SOFTWARE FOR BIOLOGICAL ANALYSIS
TABLE 16 POPULAR COMMERCIALLY AVAILABLE BIOINFORMATIC PROGRAMS
FOR NEXT-GENERATION SEQUENCING ANALYSIS
BIOSIMULATION MODELS
MARKET ANALYSIS
CHAPTER 6 BIOINFORMATICS: DATA PROCESSING AND STORAGE
MIND THE GAP
FIGURE 8 EVOLUTION OF INFORMATION TECHNOLOGY INFRASTRUCTURE
INFORMATION TECHNOLOGY INFRASTRUCTURE
TABLE 17 TOP 20 HARDWARE COMPANIES, 2010 ($MM/%)
HIGH-PERFORMANCE COMPUTING
TABLE 18 TOP SUPERCOMPUTERS, AS OF 2015
HIGH-PERFORMANCE COMPUTER CLUSTERS
CLOUD COMPUTING
FIGURE 9 SCHEMATIC REPRESENTATION OF CLOUD COMPUTING SERVICES
DATA AS A SERVICE
INFRASTRUCTURE AS A SERVICE
PLATFORM AS A SERVICE
SOFTWARE AS A SERVICE
TABLE 19 SOFTWARE AS A SERVICE RESOURCE
SECURITY AS A SERVICE
CLOUD COMPUTING CHALLENGES
FUTURE OF CLOUD COMPUTING
MARKET ANALYSIS
CHAPTER 7 BIOINFORMATIC APPLICATIONS IN PHARMACEUTICAL
RESEARCH AND DEVELOPMENT
INTRODUCTION
TABLE 20 LEADING BIOINFORMATICS DATABASES
DRUG DISCOVERY AND DEVELOPMENT PROCESS
FIGURE 10 PHASES IN THE DRUG DISCOVERY AND DEVELOPMENT PROCESS
PRECLINICAL RESEARCH: DRUG DISCOVERY PHASE
TARGET IDENTIFICATION
TARGET VALIDATION
Role of Bioinformatics in Target Identification and Validation
TABLE 21 LEADING DRUG TARGET DATABASES
LEAD IDENTIFICATION
COMPUTER-AIDED DRUG DESIGN
FIGURE 11 BIOINFORMATIC INTERDISCIPLINARY NATURE
TABLE 22 COMPUTER SIMULATION PLATFORMS
LEAD OPTIMIZATION
CLINICAL RESEARCH: DRUG DEVELOPMENT
PRECLINICAL EXPERIMENTS
LABORATORY INFORMATION MANAGEMENT SYSTEMS
TABLE 23 LEADING LABORATORY INFORMATION MANAGEMENT SYSTEM
PROVIDERS
ELECTRONIC LABORATORY NOTEBOOKS
FIGURE 12 INFORMATION SYSTEMS WITHIN THE LABORATORY
ARCHITECTURE
TABLE 24 ELECTRONIC NOTEBOOKS USED WITHIN THE RESEARCH AND DEVELOPMENT ENVIRONMENT
TABLE 25 ELECTRONIC LABORATORY NOTEBOOKS USED WITHIN
SPECIFIC AREAS OF BIOLOGY
INVESTIGATIONAL NEW DRUG APPLICATION
CLINICAL TRIALS
BIOINFORMATICS IN CLINICAL TRIAL DESIGN AND DATA COLLATION
TABLE 26 LEADING ABSORPTION, DISTRIBUTION, METABOLISM, EXCRETION AND TOXICITY PREDICTION TOOLS
NEW DRUG APPLICATION
NEW DRUG APPLICATION APPROVAL
TABLE 27 DRUG DEVELOPMENT PROCESS OVERVIEW
POST-LAUNCH ONGOING STUDIES AND PHASE IV CLINICAL TRIALS
ELECTRONIC HEALTH RECORDS
TABLE 28 LEADING ELECTRONIC HEALTH RECORD PROVIDERS, 2013
MOBILE HEALTH TECHNOLOGIES
TABLE 29 MEDICAL APPLICATIONS FOR HEALTHCARE PROFESSIONALS
RECENT PHARMACEUTICAL AND BIOINFORMATIC ALLIANCES AND PARTNERSHIPS
TABLE 30 PHARMACEUTICAL AND BIOINFORMATIC PARTNERSHIPS AND ALLIANCES
CONCLUSIONS
CHAPTER 8 MARKET TRENDS AND ANALYSIS
NORTH AMERICA
TABLE 31 NORTH AMERICAN BIOINFORMATIC MARKET BY REGION, THROUGH 2019 ($ MILLIONS)
UNITED STATES
TABLE 32 LEADING BIOINFORMATIC COMPANIES IN THE U.S.
TABLE 33 TOP 15 VENTURE CAPITAL COMPANIES MOST ACTIVE IN THE LIFE SCIENCE SECTOR, THROUGH 2012
TABLE 34 U.S. BIOINFORMATIC MARKET BY APPLICATION, THROUGH 2019 ($ MILLIONS)
TABLE 35 U.S. BIOINFORMATIC MARKET BY CATEGORY, THROUGH 2019 ($ MILLIONS)
CANADA
TABLE 36 CANADIAN BIOINFORMATIC MARKET BY CATEGORY, THROUGH 2019 ($ MILLIONS)
TABLE 37 LEADING CANADIAN BIOINFORMATIC COMPANIES
TABLE 38 CANADIAN BIOINFORMATIC MARKET BY APPLICATION, THROUGH 2019 ($ MILLIONS)
EUROPE
TABLE 39 EUROPEAN BIOINFORMATIC MARKET BY REGION, THROUGH 2019 ($ MILLIONS)
TABLE 40 LEADING EUROPEAN BIOINFORMATIC COMPANIES
U.K.
TABLE 41 U.K. BIOINFORMATIC MARKET BY CATEGORY,THROUGH 2019 ($ MILLIONS)
TABLE 42 U.K. BIOINFORMATIC MARKET BY APPLICATION,THROUGH 2019 ($ MILLIONS)
GERMANY
TABLE 43 GERMAN BIOINFORMATIC MARKET BY CATEGORY,THROUGH 2019 ($ MILLIONS)
TABLE 44 GERMAN BIOINFORMATIC MARKET BY APPLICATION,THROUGH 2019 ($ MILLIONS)
SWITZERLAND
TABLE 45 SWISS BIOINFORMATIC MARKET BY CATEGORY,THROUGH 2019 ($ MILLIONS)
TABLE 46 SWISS BIOINFORMATIC MARKET BY APPLICATION,THROUGH 2019 ($ MILLIONS)
ASIA-PACIFIC
TABLE 47 ASIA-PACIFIC BIOINFORMATIC MARKET BY REGION,THROUGH 2019 ($ MILLIONS)
INDIA
TABLE 48 INDIAN BIOINFORMATIC MARKET BY CATEGORY,THROUGH 2019 ($ MILLIONS)
FIGURE 13 KEY AREAS OF RESEARCH UTILIZING BIOINFORMATICS
TABLE 49 LEADING INDIAN BIOINFORMATIC COMPANIES
TABLE 50 INDIAN BIOINFORMATIC MARKET BY APPLICATION,THROUGH 2019 ($ MILLIONS)
CHINA
TABLE 51 CHINESE BIOINFORMATIC MARKET BY CATEGORY,THROUGH 2019 ($ MILLIONS)
TABLE 52 CHINESE BIOINFORMATIC MARKET BY APPLICATION,THROUGH 2019 ($ MILLIONS)
CONCLUSIONS
CHAPTER 9 COMPANY PROFILES
3RD MILLENNIUM INC.
ASTRID BIOSCIENCE GMBH
BIOBASE GMBH
BIOMATTERS LTD.
CLC BIOINFORMATICS
CONEXIO GENOMICS PRIVATE LTD.
COMPUGEN LTD.
DASSAULT SYSTEMES SA
DNASTAR INC.
GEOSPIZA INC.
GENOMATIX SOFTWARE GMBH
GVK BIOSCIENCES PRIVATE LTD.
GENOLOGICS LIFESCIENCES SOFTWARE INC.
GENEDATA AG
GENEVA BIOFORMATICS (GENEBIO) SA
GNS HEALTHCARE INC.
ILLUMINA INC.
MOLECULAR CONNECTIONS PRIVATE LTD.
MOLECULAR NETWORKS GMBH
NONLINEAR DYNAMICS LTD.
OCIMUM BIOSOLUTIONS LTD.
PERKIN ELMER INFORMATICS INC.
PERSONALIS INC.
SMARTGENE SERVICES SARL
REAL TIME GENOMICS INC.
CHAPTER 10 APPENDIX ONE: ACRONYMS
CHAPTER 11 REFERENCES
ENDNOTES

Bioinformatics: Technologies and Global Markets

The global bioinformatic market was $3.6 billion and $4.1 billion in 2013 and 2014, respectively. This market is expected to reach $8.0 billion in 2019 from $4.7 billion in 2015 at a compound annual growth rate of 14.2% for the period 2014-2019.

The report provides:
An overview of the global market for bioinformatics based on geography, category and application.
Analyses of global market trends, with data from 2013 and 2014, estimates for 2015, and projections of compound annual growth rates (CAGRs) through 2019.
Technological descriptions and patenting trends in bioinformatics.
Analysis of the market's dynamics, including opportunities, drivers, and restraints.
Examination of the economic environment effecting the deployment of bioinformatics.
Discussion of other influential factors, such as R&D spending in the pharmaceutical sector, the growth of agrobiotechnology, and the expanded use of microbial genomics.
Comprehensive company profiles of major players in the industry.


SCOPE OF REPORT

The scope of the study encompasses the global bioinformatic market based on geography, category and application. It provides a detailed analysis of recent advances in ‘omic technologies and examines their impact on the bioinformatic market. It discusses the ways in which bioinformatics has been utilized by the pharma and biotech industry to streamline the research and development (R&D) process and improve efficiencies. It provides a detailed analysis of leading countries, companies and technologies that will drive the field forward.

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