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UpdatesPlus-Nicotinic Receptors
By: LeadDiscovery
What's in the February 2008 edition of UpdatesPlus-Nicotinic Receptors
The February 2008 edition of UpdatesPlus-Nicotinic Receptors reports on key events identified through tracking of:
Journal Publications
Clinical Trials
Company Press Releases
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2/20/2008
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$10,000.00
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Pipeline Report - Neuronal alpha 7 nicotinic receptors: Candidates for the treatment of Alzheimers disease and Schizophrenia
By: LeadDiscovery
Neuronal alpha 7 nicotinic receptor (á7nAChR) ligands represent an emerging class of drug for the treatment of various CNS disorders associated with cognitive dysfunction. This report describes the proof of concept supporting the development
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12/1/2007
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$3,000.00
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Coxibs - Past Problems...Future Potential
By: LeadDiscovery
Spanning the field of pain, inflammation and oncology, as well as more recently for unwanted reasons, cardiovascular disease the cyclooxygenase-2 (COX-2 or Coxibs) have sat in the spot light for almost a decade now.
The
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10/1/2006
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$1,045.00
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Aurora Kinase Inhibitors: The Dawn Of A New Approach To Cancer
By: LeadDiscovery
Cell cycle inhibitors represent a key approach to the treatment of cancer. Therapeutic agents have traditionally targeted early stages of the cell cycle (ie the G1/S phase checkpoint or the S phase) or mitotic spindle
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5/1/2006
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$665.00
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Ventricular Fibrillation and Atrial Fibrillation : Emerging Antiarrhythmics In The Context of Current Devices, Interventions and Pharmacological Agents
By: LeadDiscovery
Although ventricular and atrial fibrillation represent the most common cardiac arrhymias and are associated with amongst the highest rates of cardiovascular morbidity and mortality, treatment options are suboptimal. New opportunities are however approaching the
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5/1/2006
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$2,497.00
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BAFF (BLys) & APRIL: Emerging Targets For Autoimmune Disease & Cancer Therapeutics
By: LeadDiscovery
BAFF & APRIL: Emerging Targets for autoimmune & Cancer Therapeutics offers a detailed look at BAFF and APRIL focusing on:
A detailed but easy to understand backgrounder on B-cell immunology designed to bring all drug
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1/1/2006
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$850.00
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Autoimmune Disorders & Transplant Rejection The Potential Of T-cells Targeted Therapeutics
By: LeadDiscovery
Affecting as many as 5% of the population, autoimmune disease represents a major clinical problem. Ranking alongside other major conditions such as type II diabetes, in terms of prevalence this group of diseases includes
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12/1/2005
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$2,241.00
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Histone Deacetylase Inhibitors Moving From The Bench To A Promising Companion For Classic And Targeted Cancer therapies
By: LeadDiscovery
The field of histone deacetylase inhibitors is moving into a new phase of development. The exponential growth in the level of research activity surrounding the histone deacetylases (HDACs) witnessed over the past decade has
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5/1/2005
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$665.00
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Rheumatoid Arthritis: Emerging Drug Discovery Targets And Therapeutic Candidates
By: LeadDiscovery
The autoimmune diseases are receiving increasing attention in the pharmaceutical industry as progress is made in the understanding of immune and inflammatory processes. It is predicted that the annual value of the market for drugs
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10/1/2003
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$712.00
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Asthma Therapeutics: New Treatment Options And Emerging Drug Discovery Targets
By: LeadDiscovery
It has proved to be very difficult to develop new classes of anti-asthma therapy, partly because existing drugs, especially inhaled corticosteroids and combination inhalers, are so effective. New classes of therapeutics are expected to allow
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4/1/2003
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$627.00
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Retinoids : An A-Z Guide To Their Biology, Therapeutic Opportunities & Pharmaceutical Development
By: LeadDiscovery
The retinoids play a key role in differentiation, proliferation and apoptosis and as a result over 30 naturally occurring and synthetic analogs of retinoic acid are now either in development or on the market. Retinoids
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2/1/2003
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$627.00
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