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U.S. & Asia Markets for Non-fusion Technologies in Spine Procedures

Published by: Frost & Sullivan

Published: Apr. 27, 2004


Table of Contents




1 TOTAL MARKET FOR NON-FUSION TECHNOLOGIES IN SPINE PROCEDURES



Overview

Executive Summary
Anatomy of the Human Spine
Low Back Pain & Other Spinal Disorders
Treatment of Spinal Pathologies: Non-fusion & Fusion
Is Spine Fusion Bad?
Surgical Approaches to the Human Spine
Forecast Methodology

Market Trends and Forecasts

Market Drivers
Market Restraints
Revenue Forecast

Market Segmentation

Artificial Discs
Nucleus Replacement
Dynamic Stabilization
Annular Repair
Facet Arthroplasty

Frost & Sullivan Awards

Product Differentiation Innovation Award
Competitive Strategy Award
Global Marketing Strategy Award
Entrepreneurial Company Award

2 UNDERSTANDING THE SPINE SURGERY MARKET



Population Trends

The "Baby Boomer" Wave

Discectomy market

Disc Herniation: Trends in Patient Population
Characterization of the U.S. Discectomy Market

Laminectomy Market

Characterization of the U.S. Laminectomy Market

Spine Fusion market

Indications for Spinal Fusion
Total Number of Spine Fusions
Spine Fusion Procedures by Anatomy
Characterization of the U.S. Cervical Spine Fusion Market
Characterization of the U.S. Lumbar Spine Fusion Market

Discussion

Effect of Population Trends on the Spine Surgery Market
What will the Future Demands on Spine Surgery be?

3 ARTIFICIAL DISCS



Overview

Development
Description
Patient Selection - Inclusion & Exclusion Criteria
Pre-clinical & Clinical Studies

Forecasts

Assumptions
Unit Forecast
Pricing/Price Forecast
Revenue Forecast
Cervical Discs versus Lumbar Discs: Who will lay the Golden Egg?

Competitive Structure

DePuy Spine
Synthes-Stratec
Medtronic Sofamor Danek
SpineCore

4 NUCLEUS REPLACEMENT



Overview

Development
Description
Patient Selection - Inclusion & Exclusion Criteria
Pre-clinical & Clinical Studies

Forecasts

Assumptions
Unit Forecast
Pricing Forecast
Revenue Forecast

Competitive Structure

Raymedica
Disc Dynamics
Spine Wave
Cryolife
Replication Medical

5 DYNAMIC STABILIZATION



Overview

Development
Description
Patient Selection - Inclusion & Exclusion Criteria
Pre-clinical & Clinical Studies

Forecasts

Assumptions
Unit Forecast
Pricing Forecast
Revenue Forecast

Competitive Structure

Zimmer Spine
Synthes-Stratec
Medtronic

6 ANNULAR REPAIR DEVICES



Overview

Development
Description
Patient Selection - Inclusion & Exclusion Criteria
Pre-clinical & Clinical Studies

Forecasts

Assumptions
Unit Forecast
Pricing Forecast
Revenue Forecast

Competitive Structure

Anulex Technologies
Intrinsic Therapeutics

7 FACET ARTHROPLASTY



Overview

Development
Description
Patient Selection - Inclusion & Exclusion Criteria
Pre-clinical & Clinical Studies

Forecasts

Assumptions
Unit Forecast
Pricing Forecast
Revenue Forecast

Competitive Structure

Archus Orthopedics

8 WHAT DO THE SPINE SURGEONS SAY?



Feedback from Spine Surgeons

Surgical Decision Making for Non-fusion Technologies
Expectations and Concerns

9 FUTURE MERGERS & AQUISITIONS



Scenario of the Non-fusion Spine Industry

Are Changes Imminent?

Analyses of Probable Alliances

Raymedica
Disc Dynamics
Spine Wave
Replication Medical
SpineCore

10 ASIAN PERSPECTIVE



Australia

Non-fusion Spine Technologies in Australia
Frequency of Use
Price Factor

China

Non-fusion Spine Technologies in China
Frequency of Use
Price Factor

India

Non-fusion Spine Technologies in India
Frequency of Use
Price Factor

Japan

Non-fusion Spine Technologies in Japan
Frequency of Use
Price Factor

South Korea

Non-fusion Spine Technologies in South Korea
Frequency of Use
Price Factor

11 DECISION SUPPORT DATABASES



Statistics on Asian Countries

Australia
China
India
Japan
South Korea


Abstract

Spine implants is the fastest growing segment within the $7 billion-plus U.S. orthopedic market. It has been estimated that 60 percent to 80 percent of Americans are likely to experience an episode of disabling low back pain at least once in their lifetime. The condition costs the economy about $60 billion due to lost work, medical costs, and rehabilitation. Till date, the ultimate option available to patients suffering from chronic spine-related problems, such as low-back pain, has been 'welding' together the adjacent vertebral bodies through a process called spine fusion. Although spine fusion is the current gold standard for spine care, it has several drawbacks. It disrupts the biomechanics of the spine and promotes degeneration of adjacent discs. Fusion also restricts motion of the spine units. Additionally, post-fusion surgery, patients may have to undergo several months of rehabilitation. A new generation of devices that will enable 'non-fusion' treatment of the spine is evolving. These devices will restore the natural biomechanics and motion of the spine. However, surgeons are of the opinion that fusion will still remain an important aspect of spine care since non-fusion treatment may not address all orthopedic problems of the spine. Also non-fusion treatment of the spine may not be suitable for patients above 60 years of age.

This research offers a detailed analysis of the various segments of the non-fusion devices market for spine procedures in the U.S. and Asia. The key participants in each segment are identified, and their strengths and weaknesses are discussed. Input from spine surgeons in the U.S. and Asia captured their expectations and concerns regarding the non-fusion spine devices. Feedback from spine surgeons also helped in making realistic market forecasts for the various non-fusion spine devices. In addition, the effect of the changing U.S. demographic landscape, especially the effect of the 'baby boomer' wave, on the future demands on the spine surgery markets are analyzed.

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