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Adult ADHD - Strattera Grows UpPublished by: Datamonitor Published: Mar. 18, 2004 - 51 Pages Table of ContentsEXECUTIVE SUMMARY 5 Introduction 5 Scope and coverage of the Brief 5 Key findings about the the topic 6 Strattera was the first drug approved for the treatment of adult ADHD in November 2002. Since launch, Strattera sales have steadily increased from $55m in Q1 2003 to $133m in Q4 2003, and Datamonitor expects Strattera to reach blockbuster status by 2006. 6 Shire’s Adderall XR recently received an approvable letter from the FDA for an indication in adult ADHD and J&J’s Concerta is currently in Phase III with an expected launch in 2005. Datamonitor forecasts that both drugs will see an increase in sales from gaining an indication for this market although both will also experience a decline in revenues post 2005. 7 It is currently estimated that approximately 75% of adults with ADHD present with a comorbid condition, of which anxiety and depressive disorders predominate. Datamonitor has highlighted two drug classes that may benefit from further investigation of the treatment of such comorbidities in order to increase their market share in the adult ADHD market. 8 DISEASE OVERVIEW 10 Disease definition 10 Epidemiology 14 DIAGNOSIS 19 Diagnostic guidelines 19 TREATMENT 25 Treatment guidelines 25 Pharmacological treatment 26 Stimulants 27 Non-stimulants 35 Antidepressants 40 Off-label prescribing 41 PIPELINE ANALYSIS 43 Unmet needs 43 Pipeline drugs 43 Backlash to adult ADHD? 45 APPENDIX 48 Bibliography 48 Websites 51 AbstractIntroductionWith the recent medical classification of adult ADHD and potentially twice the number of patients compared to pediatric ADHD, manufacturers are seeking new indications in this expanding and lucrative market. Lilly’s Strattera was the first drug to exploit this, and is forecast to reach blockbuster status by 2006. Consequently, manufacturers will need to differentiate their products from Strattera. Scope Overview of the epidemiology of adult ADHD, with an assessment of the untapped patient potential Discussion of the problems facing physicians in the diagnosis of adult ADHD Analysis of the current market leaders and primary contenders for market entry, with adult ADHD-specific market forecasts Exploration of product positioning and life-cycle management strategies currently used by Strattera, Adderall XR and Concerta Report Highlights Strattera was the first drug approved for the treatment of adult ADHD in November 2002. Since launch Strattera has a steady sales increase from $55m in Q1 2003 to $133m in Q4 2003, and Datamonitor has forecast Strattera to reach blockbuster status by 2006. Shire’s Adderall XR recently received an approvable letter from the FDA for adult ADHD and J&J’s Concerta is currently in Phase III with an expected launch in 2005. Datamonitor forecasts that both drugs will see an increase in sales from gaining an indication for this market, although both will also experience a decline in revenues post 2005. Approximately 75% of adults with ADHD present with a comorbid condition, of which anxiety and depressive disorders predominate. Datamonitor has highlighted two drug classes, which may benefit from further investigation of the treatment of such comorbidities in order to increase their market share in the adult ADHD market. Reasons to Purchase Analyze the commercial viability of the adult ADHD market, based on estimated patient numbers Develop market entry and consolidation strategies through an understanding of key unmet needs in the market Identify and assess novel R&D compounds in the adult ADHD pipeline Get Full Details About This Report >> |
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