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Microfluidics TechnologiesPublished by: BCC Research Published: Mar. 1, 2004 - 184 Pages Table of ContentsINTRODUCTION STUDY GOALS AND OBJECTIVES REASONS FOR DOING THE STUDY SCOPE AND FORMAT METHODOLOGY AND INFORMATION SOURCES AUTHOR'S CREDENTIALS RELATED BCC PUBLICATIONS REPORTS MONTHLY NEWSLETTERS BCC ONLINE SERVICES SUMMARY Summary Table: WORLDWIDE MARKET FOR MICROFLUIDIC TECHNOLOGIES, 1997 THROUGH 2008 ($ MILLIONS) Summary Figure: WORLDWIDE MARKET FOR MICROFLUIDIC TECHNOLOGIES, 1997-2008 ($ MILLIONS) OVERVIEW OVERVIEW DEFINITION AND INDUSTRY STRUCTURE IMPORTANCE OF MICROFLUIDICS MICROFLUIDIC COMPONENTS MICROVALVES INJECTION NOZZLES PUMPS SENSORS Table 1 SENSORS UTILIZING MICROFLUIDIC TECHNOLOGY (%) Figure 1 SENSORS UTILIZING MICROFLUIDIC TECHNOLOGY (%) MICROFLUIDIC SYSTEMS MAJOR END-USER MARKETS HIGH THROUGHPUT SCREENING (HTS) AND COMPOUND PROFILING DIAGNOSTIC AND POINT-OF-CARE (POC) INKJET PRINTING CHEMICAL ANALYSIS DRUG DELIVERY/MEDICAL PROTEOMICS DISPENSING DEFENSE-RELATED INDUSTRY CONCEPTS MICROFLUIDICS MICROSCALE PHYSICS DRUG DISCOVERY LAB-ON-A-CHIP HIGH-THROUGHPUT SCREENING POC DIAGNOSTICS MEMS MATERIALS OF CONSTRUCTION MICROFABRICATION MARKET ENVIRONMENT Table 2 KEY MARKET PARAMETERS FOR MICROFLUIDICS BASIC CONCEPTS IN MICROFLUIDICS GENERAL WHAT IS A MICROFLUIDIC DEVICE? IMPORTANCE OF MEMS Table 3 WORLDWIDE MEMS MARKET INCLUDING MICROFLUIDICS, THROUGH 2008 ($ MILLIONS) Figure 2 WORLDWIDE MEMS MARKET, INCLUDING MICROFLUIDICS, 2001-2008 ($ MILLIONS) MEMS AND MICROFLUIDICS Figure 3 WORLDWIDE MEMS AND MICROFLUIDICS MARKETS, 2001-2008 ($ MILLIONS) BASIC PRINCIPLES OF MICROFLUIDICS Pressure Driven Flow Electrokinetic Flow Passive Fluid Control Technology Figure 4 PASSIVE MICROFLUIDIC VALVE Chemical Control Hydrogels Colloidal Microspheres FINITE ELEMENT MODELING IN FLUID MECHANICS The Utility of Modeling Phase Phenomena Table 4 DESIGN OF MICROFLUIDIC DEVICES - PHASE PHENOMENA CONSIDERATIONS Heat Removal Bimetallic Actuation SURFACE CHEMISTRY Substrate Factors Surface Coatings Hydrophilic Material Figure 5 THE HYDROPHILIC EFFECT IN MICROFLUIDIC CONDUITS Hydrophobic Material Figure 6 THE HYDROPHOBIC EFFECT IN MICROFLUIDIC CONDUITS Surface Finish DIFFUSION BONDING "MICROJAWS" FOR GENETIC ENGINEERING AND THERAPEUTICS Table 5 DESIGN OF MICROFLUIDIC DEVICES - ACTUATION PRINCIPLES AND APPLICATIONS FABRICATION OF MICROFLUIDIC COMPONENTS AND SYSTEMS SENSORS ACTUATORS MICROSTRUCTURES MICROSYSTEMS Construction MICROMACHINING Photopolymerization Process Photolithography Thin Films Wet Etching Dry Etching Surface Micromachining Laser Micromachining LIGA HexSil FEATURES OF MICROSYSTEMS HYBRID MICROSYSTEMS BioMEMs CORIOLIS MASS FLOW TECHNOLOGY MATERIALS OF CONSTRUCTION Silicon PDMS and Silicone Elastomers Polyimide Table 6 FABRICATION TECHNIQUES FOR MICROFLUIDIC DEVICES RELATED TECHNOLOGY CONSIDERATIONS EDM Fluidic Driving Force GROWTH OBSTACLES Table 7 COMPARISON OF GROWTH OBSTACLES FOR MICROFLUIDIC TECHNOLOGIES GROWTH DRIVERS Table 8 KEY GROWTH DRIVERS FOR MICROFLUIDIC TECHNOLOGY ISSUES AFFECTING SALES OPPORTUNITIES ACCOUNTING FOR FACTORS WHEN PROJECTING DATA MICROFLUIDIC MARKET BY END-USER SEGMENTS OVERVIEW Table 9 WORLDWIDE MAJOR MARKET SEGMENTS FOR MICROFLUIDIC TECHNOLOGIES, THROUGH 2008 ($ MILLIONS) Figure 7 WORLDWIDE MAJOR MARKET SEGMENTS FOR MICROFLUIDIC TECHNOLOGIES, 2003 AND 2008 ($ MILLIONS) HIGH THROUGHPUT SCREENING AND COMPOUND PROFILING OVERVIEW APPLICATIONS Drug Discovery DNA Analysis Assays Compound Libraries Lab Automation MARKET FORECAST Forecast Assumptions MARKET SHARE Table 10 HTS/COMPOUND PROFILING COMPANIES -GLOBAL MARKET SHARE, 2002 (%) Figure 8 HTS/COMPOUND PROFILING COMPANIES - GLOBAL MARKET SHARE, 2002 (%) Tecan Orchid Caliper Nanogen Nanostream Aclara CLINICAL DIAGNOSTICS/POC TESTING OVERVIEW Acceptance of Technology APPLICATIONS Animal Healthcare Applications MARKET FORECAST Forecast Assumptions Table 11 WORLDWIDE POC PROJECTIONS BY TESTING CATEGORY, THROUGH 2008 ($ BILLIONS) Figure 9 WORLDWIDE POC PROJECTIONS BY TESTING CATEGORY, 2003-2008 ($ BILLIONS) Table 12 U.S. POC MARKET BY END USER - PROJECTIONS, THROUGH 2008 ($ MILLIONS) Figure 10 U.S. POC MARKET BY END USER - PROJECTIONS, 2003-2008 ($ MILLIONS) Table 13 WORLDWIDE MICROFLUIDICS-BASED POC MARKET FORECAST, THROUGH 2008 ($ MILLIONS) Figure 11 WORLDWIDE MICROFLUIDICS-BASED POC MARKET FORECAST, 1998-2008 ($ MILLIONS) MARKET SHARE Table 14 WORLDWIDE MARKET SHARE FOR GLUCOSE MONITORING EQUIPMENT MANUFACTURERS, 2002 ($ MILLIONS, %) Figure 12 WORLDWIDE MARKET SHARE FOR GLUCOSE MONITORING EQUIPMENT MANUFACTURERS, 2002 (%) Cygnus Minimed (Medtronic) Roche Spectrx/Abbott Gluko-Meditech Key Players Table 15 MICROFLUIDICS-BASED POC APPLICATIONS - KEY PLAYERS Gyros Handylab INKJET PRINTING OVERVIEW APPLICATIONS Ink Ejection Inkjet R&D Inkjet R&D (Continued) Inkjet Technology for Other Applications MARKET FORECAST Forecast Assumptions Table 16 WORLDWIDE REVENUE FORECAST FOR MICROFLUIDIC-BASED INKJET TECHNOLOGIES, THROUGH 2008 ($ MILLIONS, %) Figure 13 WORLDWIDE REVENUE FORECAST FOR MICROFLUIDIC-BASED INKJET TECHNOLOGIES, 1998-2008 ($ MILLIONS) MARKET SHARE Table 17 INKJET - WORLDWIDE COMPANY BREAKDOWN BY MARKET SHARE, 2003 (%) Figure 14 INKJET - WORLDWIDE COMPANY BREAKDOWN BY MARKET SHARE, 2003 (%) Key Players Kodak Hewlett-Packard Epson CHEMICAL ANALYSIS AND m-TAS OVERVIEW APPLICATIONS µTAS Multidisciplinary Development Effort Spatial Effects Microreactors MARKET FORECAST Forecast Assumptions Table 18 MICROFLUIDICS-BASED CHEMICAL ANALYSIS - WORLDWIDE REVENUE FORECAST, THROUGH 2008 ($ MILLIONS, %) Figure 15 MICROFLUIDICS-BASED CHEMICAL ANALYSIS - WORLDWIDE REVENUE FORECAST, 1998-2008 ($ MILLIONS) MARKET SHARE Table 19 CHEMICAL ANALYSIS - WORLDWIDE COMPANY BREAKDOWN BY MARKET SHARE, 2003 (%) Figure 16 CHEMICAL ANALYSIS - WORLDWIDE COMPANY BREAKDOWN BY MARKET SHARE, 2003 (%) Key Players Micronics Nanostream Cytoplex Biosciences Corning Intellisense Eksigent DRUG DELIVERY/MEDICAL APPLICATIONS OVERVIEW BioMEMs Dose Control APPLICATIONS Advanced Applications FABRICATION CONCERNS MICROTEETH DRUG DELIVERY CARDS Table 20 DRUG DELIVERY APPLICATIONS WORLDWIDE, 2003 Figure 17 DRUG DELIVERY APPLICATIONS WORLDWIDE, 2003 (%) MARKET FORECAST Forecast Assumptions: Table 21 MICROFLUIDICS-BASED DRUG DELIVERY - WORLDWIDE REVENUE FORECAST, THROUGH 2008 ($ MILLIONS) Figure 18 MICROFLUIDICS-BASED DRUG DELIVERY - WORLDWIDE REVENUE FORECAST, 1998-2008 ($ MILLIONS) MARKET SHARE Table 22 INSULIN PUMPS - COMPANY BREAKDOWN BY MARKET SHARE, 2003 ($ MILLIONS, %) Figure 19 INSULIN PUMPS - COMPANY BREAKDOWN BY MARKET SHARE, 2003 (%) Key Players ISSYS Debiotech Therafuse PROTEOMICS OVERVIEW Productivity Enhancement MARKET SHARE Table 23 PROTEOMICS - WORLDWIDE COMPANY BREAKDOWN BY MARKET SHARE, 2003 (%) Figure 20 PROTEOMICS - WORLDWIDE COMPANY BREAKDOWN BY MARKET SHARE, 2003 (%) Key Players Motorola Ciphergen Packard Bioscience (Perkin Elmer) COMMERCIAL DEVELOPMENTS RELATED TO PROTEOMICS Key Benefits MARKET FORECAST Forecast Assumptions: Table 24 MICROFLUIDICS-BASED PROTEOMICS APPLICATIONS - WORLDWIDE REVENUE FORECAST, 1998-2008 Figure 21 MICROFLUIDICS-BASED PROTEOMICS APPLICATIONS - WORLDWIDE REVENUE FORECAST, 1998-2008 ($ MILLIONS) DISPENSING OVERVIEW APPLICATIONS Positive-Displacement Pumps Pin Arrays Aerosol Systems Table 25 DISPENSING APPLICATIONS WORLDWIDE (%) MARKET FORECAST Forecast Assumptions: Table 26 MICROFLUIDICS-BASED DISPENSING APPLICATIONS - WORLDWIDE REVENUE FORECAST ($ MILLIONS, %) Figure 22 MICROFLUIDICS-BASED DISPENSING APPLICATIONS - WORLDWIDE REVENUE FORECAST, 1998-2008 ($ MILLIONS) DEFENSE-RELATED OVERVIEW AND APPLICATIONS Table 27 MICROFLUIDICS-BASED DEFENSE-RELATED APPLICATIONS - 2003 RESEARCH SPENDING WORLDWIDE ($ MILLIONS) Table 28 DEFENSE-RELATED MICROFLUIDICS RESEARCH ACTIVITIES DARPA PROGRAMS ARTIFICIAL MUSCLE MARKET FORECAST Forecast Assumptions: Table 29 MICROFLUIDICS-BASED WORLDWIDE DEFENSE-RELATED REVENUE FORECAST, THROUGH 2008 ($ MILLIONS, %) Figure 23 MICROFLUIDICS-BASED WORLDWIDE DEFENSE-RELATED REVENUE FORECAST, 2002-2008 ($ MILLIONS) OTHER ELECTRONIC COOLING FUEL CELLS MICROFLUIDICS COMPONENTS AND SYSTEMS BY MARKET SEGMENTS Table 30 MICROFLUIDIC SYSTEMS - KEY SYSTEM APPLICATIONS, 2003 MICROFLUIDICS COMPONENTS AND SYSTEMS…(CONTINUED) MICROFLUIDICS COMPONENTS AND SYSTEMS…(CONTINUED) MICROFLUIDICS COMPANIES Table 31 MICROFLUIDICS TECHNOLOGY - TOTAL WORLDWIDE R&D INVESTMENT ($ MILLIONS) Table 32 MICROFLUIDICS COMPANIES Table 32 (CONTINUED) Table 32 (CONTINUED) Table 32 (CONTINUED) Table 32 (CONTINUED) Table 32 (CONTINUED) ACLARA BIOSCIENCES ETAG ETAG (Continued) LABCARD CALIPER TECHNOLOGIES LABCHIP SYSTEM LabChip System (Continued) GYROS MICROLABS SPINNING DISCS PARTNERSHIPS TECAN TECAN (CONTINUED) CEPHEID SMART CYCLER NANOGEN NANOSTREAM NANOSTREAM (CONTINUED) ORCHID BIOSCIENCES FLUIDIGM FLUIDIGM (CONTINUED) BIOMICRO BIOMICRO (CONTINUED) EKSIGENT TECHNOLOGIES EKPUMPTM Figure 24 PRINCIPLE OF EKPUMPTM SMARTFLOWTM FEBIT GMBH BIOTROVE (FORMERLY ADVANCED INSTRUMENTATION SYSTEMS) MicroCHIPS SRU BIOSYSTEMS MICRONICS H-FILTER® KODAK MOTOROLA LIFE SCIENCES (FORMERLY CLINICAL MICROSENSORS) ESENSOR™ CODELINK™ MICROFLUIDIC SYSTEMS, INC. CORNING INTELLISENSE COVENTOR / TERAGENICS INTELLIGENT MICRO PATTERNING, LLC MICRALYNE, INC. µTK Table 33 MAJOR COMPETITORS' AREAS OF FOCUS - MICROFLUIDICS TECHNOLOGY Table 33 (CONTINUED) MICROFLUIDICS DEALS INTELLECTUAL PROPERTY CONSIDERATIONS Table 34 SELECTED MICROFLUIDICS-RELATED DEALS 1999-2002 Table 34 (CONTINUED) Table 34 (CONTINUED) OTHER NOTABLE DEALS BY YEAR 1999 2000 2000 (Continued) 2000 (Continued) 2001 2001 (Continued) 2001 (Continued) 2001 (Continued) 2001 (Continued) 2002 Table 35 DOMINANT BUSINESS MODELS IN THE MICROFLUIDICS ARENA PATENT LANDSCAPE (DEVELOPMENTS SINCE 1999) INTRODUCTION TRENDS BY COUNTRY Figure 25 U.S. PATENT TRENDS BY COUNTRY, JAN. 1, 1999 THROUGH SEPT. 30, 2003 (NUMBER OF PATENTS ISSUED) TRENDS BY ASSIGNEE Figure 26 SHARES OF U.S. PATENTS BY ASSIGNEE, JAN. 1, 1999 THROUGH SEPT. 30, 2003 (%) Table 36 COMPANIES AND INSTITUTIONS AWARDED THREE OR MORE NANOMATERIAL-RELATED PATENTS, SEPT. 1, 1998 THROUGH AUG. 31, 2000 TRENDS BY EMPHASIS: PRODUCTION VERSUS APPLICATION Figure 27 SHARES OF PATENTS ISSUED BY EMPHASIS, JAN. 1, 1999 THROUGH SEPT. 30, 2003 (%) OUTLOOK - TRENDS, CHALLENGES AND FORCES THAT ARE DRIVING THE INDUSTRY'S FUTURE TECHNICAL CHALLENGES TECHNICAL CHALLENGES (CONTINUED) TECHNICAL CHALLENGES (CONTINUED) FABRICATION METHODS OBSTACLES OBSTACLES (CONTINUED) OBSTACLES (CONTINUED) BUSINESS CONSIDERATIONS MICROFLUIDICS AND NANOTECHNOLOGY MICROFLUIDICS AND NANOTECHNOLOGY (CONTINUED) CONCLUSION CONCLUSION (CONTINUED) AbstractAdvances in drug discovery, genomics and laboratory automation are fueling exponential growth in the microfluidics area. This updated study details and analyzes the emerging market for microfluidic technologies and devices. With an estimated $2 billion market for microfluidics, technological breakthroughs in the life sciences and chemical analysis areas will significantly increase current demand for microfluidic products in the coming years. This report illustrates new developments and their anticipated impact, including improvements in fluid flow detection and sensitivity along with improvements in integration with robotics equipment. Critical market segments include drug discovery, drug delivery, in-vitro diagnostics, ink jet printing, chemical analysis and high-throughput screening. Additionally, five-year forecasts by segment are provided along with an assessment of the competitive landscape.Get Full Details About This Report >> |
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