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Systems Biology:Key to Unlocking the Value within the Omics Revolution

Published by: Drug and Market Development Publishing

Published: Jan. 1, 2004 - 185 Pages


Table of Contents



1 Executive Summary

Technology Background

Technologies for Systems Biology

Market Activity and Prospects

Future Trends

2 Introduction

Scope and Objectives of the Report



3 Technology Background

Definitions of Systems Biology

Computational Systems Biology

Data-Driven or Integrational Systems Biology

Evolution of Systems Biology

Origins of Systems Biology

Genomics and the Rebirth of Discovery Research in Biology

4 Technologies for Systems Biology

Data-Driven Systems Biology

Transcriptomics

Genetic Variation

Proteomics

Metabolomics

Informatics for Data-Driven Systems Biology

Progress in Data--Driven Systems Biology

Basic Systems Biology

Computational Systems Biology

Methodology

Progress in Computational Systems Biology

The Systems Biology Research Community

5 Commercial Applicability

Pharmaceutical Applications

Diagnostic Applications

Other Applications

6 Market Activity and Prospects

Systems Biology Company Business Models and Deals

7 Future Trends

8 Company Profiles

3rd Millennium, Inc.

Company Management

Company Overview

Company Financials

Technology, Research, and Development

Products and Product Pipeline

Strategic Alliances

Intellectual Property



Aclara Biosciences



Company Management

Company Overview

Company Financials

Technology, Research, and Development

Products and Product Pipeline

Strategic Alliances

Intellectual Property



Beyond Genomics



Company Management

Company Overview

Technology, Research, and Development

Products and Product Pipeline

Strategic Alliances

Intellectual Property



BioSeek, Inc



Company Management

Company Overview

Company Financials

Technology, Research, and Development

Products and Product Pipeline

Strategic Alliances

Intellectual Property



Cellzome AG



Company Management

Company Overview

Company Financials

Technology, Research, and Developmen.

Products and Product Pipeline

Strategic Alliances

Intellectual Property



Entelos, Inc.



Company Management

Company Overview

Company Financials

Technology, Research, and Development

Products and Product Pipeline

Strategic Alliances

Intellectual Property



Genedata AG



Company Management

Company Overview

Company Financials

Technology, Research, and Development

Products and Product Pipeline

Strategic Alliances

Intellectual Property



GeneGo, Inc.



Company Management

Company Overview

Company Financials

Technology, Research, and Development

Products and Product Pipeline

Strategic Alliances

Intellectual Property



Gene Network Sciences



Company Financials

Technology, Research, and Development

Products and Product Pipeline

Strategic Alliances

Intellectual Property



Gene Networks, Inc.



Company Management

Company Overview

Company Financials

Technology, Research, and Development

Products and Product Pipeline

Strategic Alliances

Intellectual Property



Genomatica, Inc.



Company Management

Company Overview

Company Financials

Technology, Research, and Development

Products and Product Pipeline

Strategic Alliances

Intellectual Property



IBM Corporation



Company Management

Company Overview

Company Financials

Technology, Research, and Development

Products and Product Pipeline

Strategic AlliancesIngenuity Systems



Company Management

Company Overview

Company Financials

Technology, Research, and Development

Products and Product Pipeline

Strategic Alliances

Intellectual Property



The Institute for Systems Biology



Company Management

Company Overview

Company Financials

Technology, Research, and Development

Products and Product Pipeline

Strategic Alliances



Paradigm Genetics



Company Management

Company Overview

Company Financials

Technology, Research, and Development

Products and Product Pipeline

Strategic Alliances

Intellectual Property



Predix Pharmaceuticals, Inc.



Company Management

Company Overview

Company Financials

Technology, Research, and Development

Products and Product Pipeline

Strategic Alliances

Intellectual Property



Protein Pathways, Inc.



Company Management

Company Overview

Company Financials

Technology, Research, and Development

Products and Product Pipeline

Strategic Alliances

Intellectual Property



Target Discovery



Company Management

Company Overview

Company Financials

Technology, Research, and Development

Products and Product Pipeline

Strategic Alliances

Intellectual Property

9 Interviews with Industry Experts

Michael French, Sr. VP, Business Development and Alliances, Entelos

Stephen Naylor, Ph.D., Consultant, Boston, Massachusetts

Colin Hill, Gene Network Sciences, CEO, President, and Chairman

Robert N. McBurney, CSO and Sr. VP. R&D, Beyond Genomics

Frank Mara, Sr. VP Marketing, Ingenuity Systems

Yury Rozenman, Senior Marketing Manger, Pharmaceutical Sector, IBM

Abstract

This Report describes the current state and future prospects of the rapidly developing systems biology field. D&MD's Systems Biology Report clearly defines what systems biology is and does. An historical overview of the field is provided and the technical and commercial background is detailed. The nature of systems biology is examined in its several manifestations; commercial applications in pharmaceutical, diagnostic, and other business segments; and market dynamics. A series of detailed profiles of companies active in the field is followed by in-depth interviews with six systems biology experts.

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