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Rapid Cycling Bipolar Disorder: Another niche indication?

Published by: Datamonitor

Published: Aug. 31, 2003 - 38 Pages


Table of Contents


TABLE OF CONTENTS



About Datamonitor 2



Executive Summary 5

Introduction 5

Scope and coverage of the brief 5



Key findings about rapid cycling bipolar disorder 5

Introduction 8

Diagnositc criteria 8

Epidemiology 10

Prevalence rate of bipolar disorders 10



Drug Treatment 14

Introduction 14

Mood stabilizers 14

Antidepressants 20

Antipsychotics 21

Other pharmacotherapies 24

Common combination pharmacotherapies 25

Treatment strategies 26

Review of treatments 27

Datamonitor conclusions 28

Unmet Market Needs 30

Strategic Recommendations 32

Increased awareness 32

Treatment guidelines 32

Shared risk scheme 32



Appendix 33

Bibliography 33

Websites 37



Abstract

Introduction
Rapid cycling bipolar disorder (RCBD) is a market with many unmet needs, although barriers to entry are high. Pharmaceutical manufacturers need to invest substantial money into clinical trials to show a drug’s efficacy, although at first glance, a low diagnosed population and poorly defined treatment strategy offers intangible returns.

Scope
* Epidemiology of RCBD, including prevalence and diagnosis rates

* Analysis of current drug treatment, which includes mood stabilizers, antidepressants, and antipsychotics

* Identification of unmet market needs

* Datamonitor’s strategic recommendations

Report Highlights
Datamonitor believes combination therapy is the future of RCBD management. The recommended approach is for add-on rather than initial co-therapy. However, improved, better defined, and standardized treatment guidelines should be published.

The treatment strategy for rapid cycling bipolar is major barrier to the quality of treatment. Datamonitor believes that this is not due to a lack of efficacious drugs, but that low levels of research into drug combinations has resulted in an unclear treatment strategy.

Reasons to Purchase
* Identify current treatment options and unmet needs in the market

* Assess market opportunities and potential, and the barriers to market entry

* Understand the role of government in defining treatment strategies



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