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Drug Markets by Price Tier

Published by: BCC Research

Published: Nov. 1, 2003 - 151 Pages


Table of Contents


Introduction

Prescription Drug Pricing Policy And Drug Industry Profitability



Study Background



Study Goals And Objectives



Intended Audience



Scope And Format



Methodology And Information Sources



Analyst Credentials



Related Bcc, Inc. Research



Bcc Online Services


Executive Summary

Summary Table: U.S. Prescription Drug Market By Price Segment, Through 2008 ($ Billions)


Overview Of U.S. Prescription Drug Market

Market Size And Segmentation



Figure 1 Trends In U.S. Prescription Drug Expenditures Vs. Total Health Care Expenditures, 2000-2002 ($ Billions)



Figure 1 (Continued)



Therapeutic Category



Comparison Of Therapeutic Drug Sales



Figure 2 U.S. Prescription Market Shares By Therapeutic Category, 2002 (Percent Of Total Sales)



Sales/Distribution Channels



Sales Channels



Figure 3 U.S. Prescription Drug Sales Channels, 2002 (% Of Total Sales)



Figure 3 (Continued)



Wholesale Distribution Channels



Direct Distribution



Figure 4 U.S. Prescription Drug Manufacturer Direct Sales To Dispensers (%)



Wholesalers



Rising Cost Of Prescription Drugs



Recent Price Trends



Figure 5 Trends In Average U.S. Retail Prescription Prices, 1990-2002 (Average Dollars Per Prescription)



Figure 5 (Continued)



Forces Driving Up Costs


Prescription Drug Basket

Table 1 Average Value Of Prescription Drug Basket, 2002 ($)



Central Nervous System Agents



Table 2 Sales, Number Of Prescriptions And Average Value Of Best Selling Cns Agents In The U.S., 2002



Cardiovascular Agents



Table 3 Sales, Number Of Prescriptions And Average Value Of Best Selling Cardiovascular Agents In The U.S., 2002



Gastrointestinal Agents



Table 4 Sales, Number Of Prescriptions And Average Value Of Best-Selling Gastrointestinal Agents In The U.S., 2002



Respiratory Agents



Table 5 Sales, Number Of Prescriptions And Average Value Of Best-Selling Respiratory Agents In The U.S., 2002



Anti-Infective Agents



Table 6 Sales, Number Of Prescriptions And Average Value Of Best-Selling Anti-Infective Agents In The U.S., 2002



Genito-Urinary Agents



Table 7 Sales, Number Of Prescriptions And Average Value Of Best-Selling Genito-Urinary Agents In The U.S., 2002



Musculo-Skeletal Agents



Table 8 Sales, Number Of Prescriptions And Average Value Of Best-Selling Musculo-Skeletal Agents In The U.S., 2002



Anti-Cancer Agents



Table 9 Sales, Number Of Prescriptions And Average Value Of Best-Selling Anti-Cancer Agents In The U.S., 2002



Dermatological Agents



Table 10 Sales, Number Of Prescriptions And Average Value Of Best-Selling Dermatological Agents In The U.S., 2002



Blood Agents



Table 11 Sales, Number Of Prescriptions And Average Value Of Best-Selling Blood Agents In The U.S., 2002



Diabetes Drugs



Table 12 Sales, Number Of Prescriptions And Average Value Of Best-Selling Diabetes Drugs In The U.S., 2002



Diuretics



Table 13 Sales, Number Of Prescriptions And Average Value Of Best Selling Diuretics In The U.S., 2002



Hormone Supplements And Contraceptives



Table 14 Sales, Number Of Prescriptions And Average Value Of Best-Selling Hormone Supplements/Contraceptives In The U.S., 2002



Ophthalmic Agents



Table 15 Sales, Number Of Prescriptions And Average Value Of Best-Selling Ophthalmic Agents In The U.S., 2002


Public And Private Sector Responses To Rising Drug Costs

Private Sector Responses To Rising Drug Costs



Increasing Use Of Generic Drugs



Figure 6 Trends In Generic Drug Share Of U.S. Prescriptions, 1990-2002 (Percent Of Total Number Of Prescriptions)



Figure 7 Average Cost Of Generic Vs. Brand-Name Prescription Drugs, 2001 ($)



Growing Popularity Of Discount Sales Channels



Growth Rates



Figure 8 Growth Rates By Prescription Distribution Channel, 2001-2002



Projected Market Shares



Figure 9 Projected Changes In Prescription Drug Retail Market Shares, 2002-2008 (Percent Of Total Retail Sales)



International Purchases



Group Purchasing Organizations



Group Purchasing Organizations (Continued)



Rebate Negotiations With Drug Manufacturers



Development Of Pharmacy Networks



Formulary Management



Drug Utilization Reviews



Generic Drug Substitution



Disease State Management Programs



Impact Of Pbms On Drug Costs



Prescription Drug Discount Card Programs



Program Features



Advantages And Disadvantages



Manufacturers Discount Cards



Table 16 Summary Of Manufacturer Drugs Discount Card Programs



Table 16 (Continued)



Affinity Organization Programs



Private Programs



Public Sector Responses To Rising Drug Costs



Federal Programs



Medicare



Medigap



Medicare+Choice



Pharmacy Plus Waivers



Medicaid Drug Rebate Program



Other Federal Discount Programs



Public Health Service (340b) Discount Program



Federal Supply Schedule



"Big 4" Federal Ceiling Price



Sub-Ceiling Prices



State Programs



State Drug Discount Card Programs



Bulk Pharmaceutical Purchasing



Supplemental State Rebate Programs



Reduced Reimbursements



Legal Environment



Cost Controls


Major Price Segments

Definitions



Pharmaceutical Pricing Terms



Table 17 Pharmaceutical Pricing Definitions



Table 17 (Continued)



Price To Final Purchaser



Table 18 Final Drug Pricing For Different Types Of Customers ($)



Cash Customers



Private Insurers



Medicaid



Price Segments



Figure 10 Major Price Breaks In The U.S. Prescription Drug Market (Average Cost For A Representative Basket Of Prescription Drugs)



Cash Customers



Table 19 Retail Cash Customer Cost Of Prescription Drug Basket, By Type Of Outlet ($)



Savings Mechanisms Impact



Other Private Buyers



Public Sector Buyers



Public Sector Buyers (Continued)


Trends In Prescription Drug Price Segments

Sales By Price Segment, 2000-2002



Market Shares



Figure 11 Prescription Drug Market Shares By Price Segment, 2002 (Percent Of Total Sales)



Growth Trends, 2000 To 2002



Table 20 U.S. Prescription Drug Sales Trends By Price Segment, 2000-2002 ($ Billions, Percent Of Total Sales)



Cash Customers



Insurers And Pbms



Hospitals, Hmos And Other Health Care Providers



Medicaid



Federal Supply Schedule



340b Sales



Federal Ceiling Price



Dva/Dod National Contracts



Projected Sales, 2003 Through 2008



Overall Market Trends, 2003 Through 2008



Figure 12 Overall Trends In The U.S. Prescription Drug Market, 2000-2008 ($ Billions)



Figure 12 (Continued)



Growth Trends By Price Segment, 2003 Through 2008



Table 21 Prescription Drug Sales Trends By Price Segment, Through 2008 ($ Billions, Percent Of Total Sales)



Retail Drug Sales



Figure 13 Projected Total Retail Expenditures On Prescription Drugs, 2002-2008* ($ Billions)



Non-Medicaid Retail Market



Figure 14 Cash Customer Share Of Non-Medicaid Retail Prescription Market, 2000-2008 (Percent Of Total Non-Medicaid Retail Market)



Cash Customer Sales Projections For 2003 Through 2008



Figure 15 Projected Prescription Drug Sales To Cash Customers, 2002-2008 ($ Billions)



Insurers And Pbms Sales Projections 2003 Through 2008



Table 22 Projected Prescription Sales To Insurers/Pbms, Through 2008 ($ Billions)



Medicaid



Figure 16 Trends In Prescription Drugs As A Percentage Of Total Medicaid Spending, 1998-2002 (% Of Total Medicaid Spending)



Figure 16 (Continued)



Figure 17 Projected Trends In Medicaid Spending On Prescription Drugs, 2002-2008 ($ Billions)



Figure 17 (Continued)



Hospitals, Hmos, And Other Large Health Care Providers



Figure 18 Trends In Prescription Drug Sales As A Percentage Of Total Hospital And Other Health Care Provider Costs, 2000-2002



Hospital And Other Healthcare Sales Projections 2003 Through 2008



Federal Supply Schedule



Figure 19 Projected Trends In Federal Supply Schedule Spending On Prescription Drugs, 2002-2008 ($ Billions)



340b Prices



Figure 20 Projected Trends In 340b Spending On Prescription Drugs, 2002-2008 ($ Billions)



Federal Ceiling Prices



Department Of Defense And Veterans Administration Healthcare Expenditures



Figure 21 Projected Increases In Dod/Dva Medical And Healthcare Spending, 2002-2008 ($ Billions)



Figure 21 (Continued)



Figure 22 Total Dod/Dva Prescription Drug Expenditures, 2000-2008 ($ Billions)



Figure 22 (Continued)



Figure 23 Projected Trends In Dva/Dod Prescription Drug Expenditures Under Fcp, 2002-2008 ($ Billions)



Figure 23 (Continued)



National Contracts



Figure 24 Projected Trends In Dva/Dod Prescription Drug Expenditures Under National Contracts, 2002-2008 ($ Billions)



Figure 24 (Continued)



Market Share By Price Segment, 2003 Through 2008



Figure 25 Prescription Drug Market Shares By Price Segment, 2003 And 2008 (Percent Of Total Sales)


Developments That Could Influence Baseline Projections

"Discount-Only" Programs



Vermont Pharmacy Discount Program



"Healthy Maine" Program



Future Initiatives



Medicare Prescription Drug Benefit



Recent Administration Proposals



Summary Of President’s Medicare Plan



Congressional Proposals



Impacts



Three Legislative Scenarios



Scenario Impacts On Drug Sales



Table 23 Baseline Prescription Drug Sales Vs. Scenarios 1-3, 2003 And 2008 ($ Billions)



Scenario Impacts On Market Price Structure



Figure 26 Price Structure Of Prescription Drug Market Under Different Scenarios, 2008 (% Of Total Sales)



Scenario 1 (Medicare Prescription Drug Benefit) Description



Impact On Drug Sales And Market Structure By Price Segment



Table 24 Potential Impact Of Medicare Prescription Drug Benefit On Market Size And Structure By Segment, 2003 Through 2008 ($ Billions)



Scenario 2 (State Discount Cards Only) Description



Impact On Drug Sales And Market Structure By Price Segment



Impact On Drug Sales And Market Structure By Price Segment (Continued)



Table 25 Potential Impact Of State Discount-Only Cards On Market Size And Structure, 2003 Through 2008 ($ Billions)



Scenario 3 (Medicaid Prescription Drug Benefit Plus State Discount-Only Card For Low-Income Uninsured) Description



Impact On Drug Sales And Market Structure By Price Segment



Table 26 Potential Impact Of Medicare Drug Benefit Plus State Discount-Only Cards On Market Size And Structure, 2003 Through 2008 ($ Billions)


Prescription Drug Industry

Leading Drug Manufacturer Revenues



Table 27 Top U.S. Drug Company Revenues, 2000-2002 ($ Billions)



Leading Drug Manufacturer Profitability



Table 28 Top U.S. Drug Company Profitability, 2000-2002 (Net Income As A Percent Of Total Revenues



Table 29 Most Profitable Fortune 500 Industries, 2002



Fortune 500 Drug Company Operating Performance



Figure 27 Fortune 500 Drug Companies’ Application Of Revenues, 2002 (Percent Of Total Revenues)



Figure 27 (Continued)



Pharmaceutical Wholesalers



Financial Performance



Table 30 Selected Drug Wholesaler Financial Performance, 2000-2002 ($ Billions/Percent)



Table 30 (Continued)



Operating Performance



Figure 28 Major Drug Wholesaler Application Of Revenues, 2002 (Percent Of Total Revenues)



Figure 28 (Continued)



Pharmacies And Other Drug Retailers



Financial Performance



Table 31 Selected Drug Retailer Financial Performance, 2000-2002 ($ Billions/Percent)



Operating Performance



Figure 29 Selected Drug Retailer Application Of Revenues, 2002 (Percent Of Total Revenues)


Impacts Of Price Segmentation

Impact Of Price Segments On Overall Prescription Drug Costs



Figure 30 Trends In Discount Sales Vs. Average Price Of Prescription Drugs, 2000-2002 (2000 = 1.0)



Impact Of Price Segments On Prices Paid By Specific Drug Customer Groups



Impact Of Price Segments On Size And Patterns Of Demand For Prescription Drugs



Impact Of Price Segments On Pricing Transparency And Decision-Making



Impact Of Price Segments On Drug Industry Financial Performance



Value Chain Analysis



Figure 31 Average Prescription Drug Value Chain ($)



Value Chain Analysis By Price Segment



Table 32 Value Chain By Price Segment ($)



Cash Sales



Insurers/Pbms



Hospitals/Hmos



Medicaid



Federal Programs



Profitability Impacts Of Potential Changes In Price Structure



Impact On Drug Manufacturers



Table 33 Impact Of Sales Projections On Drug Manufacturers’ Profitability, Through 2008



Drug Retailers



Conclusions



Conclusions (Continued)


Appendix

State Discount Drug Programs For Seniors



Table 34 State Drug Discount Program Characteristics



Table 34 (Continued)



Table 34 (Continued)



Table 34 (Continued)



Prescription Drug Basket Prices



Table 35 Independent Pharmacy Prescription Drug Basket Prices, 2003



Table 35 (Continued)



Table 36 Chain Pharmacy Prescription Drug Basket Prices, 2003



Table 37 Mass Merchants Prescription Drug Basket Prices, 2003



Table 38 Mail Order Prescription Drug Basket Prices, 2003



Table 39 Internet Pharmacy Prescription Drug Basket Prices, 2003



Table 40 Offshore Pharmacy Prescription Drug Basket Prices, 2003



Table 41 Insurers/Pbms Prescription Drug Basket Prices, 2003



Table 42 Hospital/Hmo Prescription Drug Basket Prices, 2003



Table 43 Medicaid Prescription Drug Basket Prices, 2003



Table 44 Federal Supply Schedule Prescription Drug Basket Prices, 2003



Table 45 340b Price Prescription Drug Basket Prices, 2003



Table 46 Federal Ceiling Price Prescription Drug Basket Prices, 2003



Table 47 Va/Dod National Contract Prescription Drug Basket Prices, 2003



Company Financial Data



Financial Statement Data



Table 48 Largest U.S. Drug Manufacturers 2002 Financial Results



Table 49 Largest U.S. Drug Wholesalers 2002 Financial Results



Table 50 Selected U.S. Drug Retailers 2002 Financial Results



Abstract

The U.S. prescription drug market exhibits a complicated price structure, in which the price of a prescription can vary by 200% or more, depending on where the prescription is bought and who pays for it. While a number of recent studies have addressed the price of prescription drugs, they have typically examined it from a single perspective, such as the price of generics or the impact of high prescription prices on seniors. There is thus a need for an up-to-date study that addresses the growing trend towards price segmentation of the U.S. prescription drug market in its totality, and the business impact that this highly price-segmented market has had on manufacturers, distributors and dispensers of prescription drugs. This study uses a basket of widely used prescription drugs to identify the major price breaks in the market, and develops detailed market projections for each price tier through 2008.

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