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High Density Multiplexed Assays: Obstacles & Opportunities for Bioscience Markets

Published by: Drug and Market Development Publishing

Published: Aug. 9, 2003 - 100 Pages


Table of Contents



1 Executive Summary



2 Introduction To Multiplexed Assays
    Limitations of Conventional Assays

    Enter Multiplexed Assays

    Scintillation Proximity Assay (SPA) - 1991

    Electrochemiluminescence (ECL)

    Multiplexed Assay Technologies Today

    Luminex

    Illumina

    Quantum Dot

    Nanoplex

    3D Molecular Sciences

    The Need for Multiplexing

    Drug Discovery and Development

    Clinical Diagnostics

    Benefits of Multiplexing


3 Applications of Multiplexed Assays Under Development
    Genomics

    SNP Profiling

    Pharmacogenomics

    Gene Expression Profiling

    Proteomics

    Immunoassay

    Glycomics


4 Future Trends Impacting Multiplexed Technologies
    Miniaturized Flow Cytometers

    Particle Separation & Recovery

    Large Scale Protein Synthesis


5 Conclusions
    High Density Multiplexing Drive

    Key Competitive Advantages of Multiplexed Assay Technologies Over Microarrays

    Key Application Areas for Multiplexed Assays (High-throughput Screening, Clinical

    Diagnostics, etc.)

    Key Technological Limitations in Extending Low Density Multiplexed Assays (<50)

    to High Density Multiplexed Assays

    Impact of Technologies on Trends in Stratifying Patients


6 Company Profiles
    Ambrigen, LLC

    BD Biosciences

    Corning

    Fluidigm

    GenoSpectra

    Guava Technologies

    Illumina

    Luminex

    Nanosphere

    NanoPlex

    Pharmaseq

    Quantum Dot

    SmartBead

    3D Molecular Sciences



7 References and Resources



8 Glossary and Abbreviations

Abstract

D&MD’s High Density Multiplexed Assays Market Analysis Report is the only publication focused solely on the increasing commercial interest in multiplexed assay technologies. This Report identifies both the technological and strategic reasons in support of high density multiplexed assay technologies becoming a major player in disease and patient stratification over the next five years, especially in major areas such as cancer—making it essential reading for those decision-makers in the pharmaceutical, biotechnology, and clinical diagnostic industries.

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