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HIV Update 2002 (10) - October

Published by: Datamonitor

Published: Nov. 19, 2002 - 21 Pages


Table of Contents




Overview

Introduction

Provides an account of all the key market events that took place during October

2002. Key events include new product launches, clinical trial data and

conference findings.

Scope

Key events are analyzed in the HIV market during October

Coverage includes emerging market headlines, R&D pipeline data, epidemiology

and disease specific factors

Reasons to Purchase

Stay informed of all of the important market led events taking place in the

HIV market

Gain insight into the likely market impact of the events that took place in

October 2002 in the HIV market

Report Highlights

Future of HIV therapy lies in simplication of drug regimens

Effective capture of switching patient populations will determine future

commercial returns

Structured treatment interruptions will play an important role in future HIV

treatment

DRIVERS AND TRENDS

Simplification of HIV therapy will start to play a more dominant role in the

next two to three years. Strategies to reduce pill burden and dosage

requirements will need to be driven by patient unmet needs. To compete

effectively in the HIV sector, competitors should seek to reformulate existing

products and develop novel products with once daily dosing profiles.

The HIV market is driven to a large extent by drug switching, especially in

patients entering latter stage therapy. This is due to the nature of the viral

infection and the fast mutation rate of the virus. Datamonitor forecasts an

increase in latter stage patients in the next two to three years. HIV drug

manufacturers should continue to target this niche patient population to

generate the greatest revenue.

Structured treatment interruptions is a treatment strategy that will

experience increased use in the near future. This strategy may be used for a

number of different patient populations. If patient compliance increases due

to a decrease in side effects with this treatment strategy, patients may be

kept longer on these strategies. Thus, the long-term profitability of drugs

used in these patients will increase.

COMPANY HEADLINES

A summary of the latest events from a company perspective

GlaxoSmithKline Faces Amended Lawsuit Regarding Patent Rights

RESEARCH AND DEVELOPMENT HEADLINES

A summary of the key events from a pipeline drug perspective

Clarithromycin Not Best Choice for MAC Prophylaxis in HIV Patients Treated

with Zidovudine

Once Daily Regimens Effective in Treatment Naïve Patients

2002: The Third Wave of HIV Vaccine Development

Switching to Sustiva Beneficial in Children on Protease Inhibitors

Filgrastim May Prevent Decrease in Viral Load Associated with PI Therapy

Atazanavir Shows Good Safety and Efficacy in Treatment- Naive Patients

DISEASE SPECIFIC HEADLINES

An overview of the epidemiological, research and clinical perspective

HIV Incidence in Intravenous Drug Users Decreases in the US

Supervised Treatment Interruption of HIV Treatment May be Effective and Safe

HAART May Not Contribute to Cardiovascular Risk in the Short Term

Wild-type Virus Persists in Treatment-Experienced HIV-infected Children

HIV Replication Can Be Blocked by RNA Interference Techniques

Treatment for FIV Shows Efficacy in HIV

Drug Resistance Common in Pediatric HIV-infected Individuals

Call for AIDS Vaccine Intensifies

HAART-Related Dyslipidemia Treated by Diet

PI Use May Accelerate Coronary Atherosclerosis

EMERGING MARKETS HEADLINES

A summary of the key events from the emerging markets

CIA Highlights HIV Explosion Risk

HIV Individuals in Thailand May Receive Cheap AIDS Drug

Africa AIDS Drugs Illegally Re-exported to EU

No Resolution Over Supply of Cheap Drugs to WTO Nations





Abstract

This brief provides an account of all the key market events that took place during October 2002. Key events include new product launches, clinical trial data and conference findings.Key events are analyzed in the HIV market during OctoberCoverage includes emerging market headlines, R&D pipeline data, epidemiology and disease specific factorsFuture of HIV therapy lies in simplication of drug regimensEffective capture of switching patient populations will determine future commercial returnsStructured treatment interruptions will play an important role in future HIV treatmentStay informed of all of the important market led events taking place in the HIV marketGain insight into the likely market impact of the events that took place in October 2002 in the HIV market

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