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42nd ICAAC 2002 - Biodefense and Emerging Infections

Published by: Datamonitor

Published: Nov. 28, 2002 - 42 Pages


Table of Contents






Overview

Introduction

The Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) is

the world's premier meeting on infectious diseases and antimicrobial agents,

organized by the American Society for Microbiology. This Brief discusses some of

the keynote lectures at the 42nd ICAAC 2002, focusing on emerging and

re-emerging infections and the increasing threat of bioterrorism.

Scope

The key pathogens and bioterrorism threats are identified. Incentives for

developing new products for biodefense are discussed.

Emerging and re-emerging infections are profiled. Key commercial opportunities

to develop and commercialize relevant products are identified.

Report Highlights

The Bioterrorism related pharmaceutical market can offer potential benefits for

smaller niche players. Whilst the potential for blockbusters is limited,

government grants can lead to assured revenues, without the need for extensive

detailing activities. In addition, the publicity surrounding platform

technologies arising from government purchase of such products can give a major

boost to small players at minimal cost.

The low incidence of rare and emerging infectious diseases, such as West Nile

disease, present market opportunities for prophylactics, if not for novel

therapeutics. Given the probable reluctance of government agencies to reimburse

prophylactic products in non-risk groups, there is potential to introduce

schemes such as co- or full- patient payment.

Reasons to Purchase

Identify the commercial potential of entering into biodefense and emerging

disease niche markets

Understand how compulsory licensing could act as a major disincentive to

expanding the indication of existing products to meet bioterrorist threats.

DRIVERS AND TRENDS

The keynote lectures at the 42nd ICAAC 2002 focused on emerging and re-emerging

infections and the increasing threat of bioterrorism.

The events of September 2001 highlighted the fact that Western civilization is

not unassailable, and that the unpredictability of terrorist attacks are a

realistic threat to the lives and economies of target countries. There has,

therefore, been increasing government activity to prepare for the threat of

further such attacks. The market for biodefense is guaranteed but limited. There

are, however, a number of factors that could attract smaller companies to enter

the market. Likewise, the market for emerging infections, such as West Nile

Virus, is highly specific. This brief explores the commercial opportunities to

be found within both markets.

BIOTERRORISM

What is the current market potential for biodefense products? What are the risks

involved in market entrance? This section provides:

An overview of the pathogens that the CDC considers to be the most dangerous

agents that could be used as bioterrorist weapons

The commercial opportunities for companies looking to enter this market are

discussed, alongside the risks involved in the development of biodefense

agents

Anthrax and smallpox are explored in greater detail, as the two agents that

the CDC is currently giving highest priority to, including an assessment of

current and future product pipelines.

EMERGING AND RE-EMERGING INFECTIONS

Emerging and re-emerging diseases can pose a threat to entire populations. The

most recent emerging disease to hit the headlines in the US is West Nile Virus

(WNV). This section of the brief summarizes the epidemiology of the disease, and

current and future product pipelines. The potential strategies to maximize

revenue gained from entering this market are also discussed.

In addition to WNV, the potential threats of a major flu pandemic, and current

strategies that are in place to deal with this eventuality are discussed.

ACTION POINTS

Understand the key themes arising from the 42nd ICAAC conference

Identify the commercial potential of entering into the biodefense market

Pinpoint current economically important emerging infections

DATASETS

Table 1: CDC classification of potential agents of bioterrorism

Table 2: Potential agents of bioterrorist attacks

Table 3: Current anthrax products for treatment and prophylaxis

Table 4: Pipeline products for anthrax treatment and prophylaxis

Table 5: Current smallpox vaccines in development

Table 6: Companies developing West Nile Virus prophylaxis

Table 7: Currently manufactured influenza vaccines

Table 8: Marketed products used for influenza treatment

Figure 1: Influenza Pandemics 1900-2000





Abstract

The Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) is the world's premier meeting on infectious diseases and antimicrobial agents, organized by the American Society for Microbiology. This Brief discusses some of the keynote lectures at the 42nd ICAAC 2002, focusing on emerging and re-emerging infections and the increasing threat of bioterrorism.The key pathogens and bioterrorism threats are identified. Incentives for developing new products for biodefense are discussed.Emerging and re-emerging infections are profiled. Key commercial opportunities to develop and commercialize relevant products are identified.The bioterrorism-related pharmaceutical market can offer potential benefits for smaller niche players. Whilst the potential for blockbusters is limited, government grants can lead to assured revenues, without the need for extensive detailing activities. In addition, the publicity surrounding platform technologies arising from government purchase of such products can give a major boost to small players at minimal cost.The low incidence of rare and emerging infectious diseases, such as West Nile disease, present market opportunities for prophylactics, if not for novel therapeutics. Given the probable reluctance of government agencies to reimburse prophylactic products in non-risk groups, there is potential to introduce schemes such as co- or full- patient payment.Identify the commercial potential of entering into biodefense and emerging disease niche marketsUnderstand how compulsory licensing could act as a major disincentive to expanding the indication of existing products to meet bioterrorist threats.

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