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HIV Update 2002 (9) - September

Published by: Datamonitor

Published: Oct. 22, 2002 - 20 Pages


Table of Contents




Overview

Introduction

The monthly HIV update provides Datamonitor's assessment of the key market

events that took place during September 2002. Key events include new product

launches, clinical trial data and conference findings.

Scope

Key events are analyzed in the HIV market during September

Gain insight into the likely market impact of the events that took place in

September 2002 in the HIV market.

Report Highlights

Novel pipeline therapeutics eyed to hit the market in 2003-2004 A number of HIV

drug manufacturers have pipeline drugs that are anticipated to achieve market

approval in the next one to two years. One drug of immediate interest is Roche’s

fusion inhibitor, Fuzeon. This drug has attracted substantial patient and

physician interest in the last year. However, its complex manufacturing process

and expensive raw ingredients will increase its price point.

Research concentrates on pediatric HIV treatment Much of the current research on

HIV treatment centers around the adult population. However, in attempting to

stem the rate of HIV transmission, the emphasis has been placed on the

population that willgenerate the greatest revenue. However, there is money to be

made on the pediatric and neonatal population.

Reasons to Purchase

Stay informed of all of the important market led events taking place in the

HIV market

Gain insight into the likely market impact of the events that took place in

September 2002 in the HIV market.

DRIVERS AND TRENDS

Novel pipeline therapeutics eyed to hit the market in 2003-2004

Research concentrates on pediatric HIV treatment

COMPANY HEADLINES

A summary of the latest events from a company perspective

Triangle Resolves Patent Disputes for Amdoxovir

RESEARCH AND DEVELOPMENT HEADLINES

A summary of the key events from a pipeline drug perspective

Durable Virologic Response for Salvage Patients on Protease Inhibitor-Based

Regimens

Kaletra Implicated in Causing Cardiovascular Side Effects

Roche Submits NDA for Fuzeon (T-20)

EU Approval for Saquinavir-Ritonavir Combination

DISEASE SPECIFIC HEADLINES

An overview of the epidemiological, research and clinical perspective

HIV Therapy and Poor Adherence: All the pitfalls, and None of the Benefits

Pediatric Response to HAART is Independent of Viral Subtype

Lack of Adherence to Neonatal Prophylaxis in Mothers Without Social Support

Supervised Treatment Interruption of HIV Treatment May be Effective and Safe

Number of Resistance Mutations Can Predict Therapeutic Outcome in Salvage HIV

Patients

Discontinuation of Successful HAART Results in Gradual Decline in CD4 Levels

Genital Wart Risk Increased By HIV in Women with HPV

Many CD4 T Cells are HIV-specific in Patients Undergoing HAART

Structured treatment interruptions does not improve HIV-specific immune

response in chronically infected patients

Women May be Able to Delay HIV Therapy Until CD4 Counts Reach 200 Copies/ml

Use of Nonoxynol-9 May Increase Risk of HIV Transmission

EMERGING MARKETS HEADLINES

A summary of the key events from the emerging markets

Generic AIDS drug approved in China

HIV and AIDS Rates Skyrocketing in Eastern Europe



Abstract

Introduction: The monthly HIV update provides Datamonitor's assessment of the key market events that took place during September 2002. Key events include new product launches, clinical trial data and conference findings. Scope: * Key events are analyzed in the HIV market during September * Gain insight into the likely market impact of the events that took place in September 2002 in the HIV market. Report Highlights: Novel pipeline therapeutics eyed to hit the market in 2003-2004 A number of HIV drug manufacturers have pipeline drugs that are anticipated to achieve market approval in the next one to two years. One drug of immediate interest is Roche's fusion inhibitor, Fuzeon. This drug has attracted substantial patient and physician interest in the last year. However, its complex manufacturing process and expensive raw ingredients will increase its price point. Research concentrates on pediatric HIV treatment Much of the current research on HIV treatment centers around the adult population. However, in attempting to stem the rate of HIV transmission, the emphasis has been placed on the population that willgenerate the greatest revenue. However, there is money to be made on the pediatric and neonatal population. Reasons to Purchase: * Stay informed of all of the important market led events taking place in the HIV market * Gain insight into the likely market impact of the events that took place in September 2002 in the HIV market.

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