Providing market research reports, industry analysis, company profiles and country reports for strategic planning, competitive intelligence, marketing and business research.
Search for Market Research Reports:    

Fierce Competition for a Shrinking HCV Market

Published by: BioSeeker Group AB

Published: Oct. 21, 2002 - 55 Pages


Table of Contents


Executive Summary


Methodology


Information Sources


Analysts


Introduction


HCV Incidence From 240,000 To 25,000 In 20 Years


  • Figure 1 - Decreasing HCV Incidence
  • Figure 2 - Decreasing HCV Prevalence


Intravenous Transmission


A Growing Market In The Short Term


  • Figure 3 - HCV Market Size Estimations


Current Treatment Older Than The Virus


Drug Development Obstacles And Promises


Current Treatments - A Duel Between Two Companies


Genotype 1 Prevalent And Resistant


Interferon Yielding Modest Sustained Virological Response


Pegylation Improves Efficacy And Administration


The Launch Of Generic Ribavirin


Combination Therapy Cures Half Of The Patients


  • Figure 4 - An Anti-HCV Collaborative Cluster


Disturbing Side Effects


Will Future Treatments Be Revolutionizing?


Immunomodulators - Capitalizing The Immediate Opportunity


  • Company Activity: Big Pharma & Small Biotech
  • Triangle Drama In Human Lactoferrin R&D
  • Viragen In A Central Role For Success?
  • New Drug Delivery For Interferon
  • Intermune Well Seated?
  • Recombinant Fusion Protein Up For Proof
  • Combinatory Treatment With Three Drugs
  • A Long Line Of Company Collaborations Tie Immunomodulars Together
  • Figure 5 - Zandaxin Increases Resopnse Rates
  • Alternative To Ribavirin


Protease Inhibitors - A Molecular Approach

  • Small-Molecule Inhibitors
  • Peptide-Based Inhibitors
  • Ns4a Inhibitors
  • Macromolecular Inhibitors
  • Company Activity: At Least Six Of The Big Pharmas Involved


Prophylactic Vaccines Eradicating HCV?

  • Research Re_Earch
  • Company Activity: Almost 20 Companies With Interest In HCV Vaccines
  • Connection Of Companies Building The Core Of Genencor's Strength
  • Box 1. Results From Innogenetics’ Phase Ii Clinical Trial
  • Will Innogenetics Be The First With A Vaccine?
  • A Strong Alliance In The Dna Vaccine Business


Conclusions: Has The Train Already Passed?

  • Table 1 - Competitive Evaluation Of Short, Medium And Long Term Therapeutics For The HCV
    Market
  • Figure 6 - Predicted Number Of HCV Positive Patients In Need Of Treatment


Index


Disclaimer


Abstract

Hepatitis C virus (HCV) has already caused a global epidemic, but the worst may yet be to come. According to the CDC nearly 4 million people are or have been infected with HCV in the U.S. alone. Of these, 2.7 million have an ongoing chronic infection, the majority being between 40 to 60 years old. A fourfold increase in the number of adults diagnosed with chronic HCV infection is projected from 1990 to 2015, since most persons with chronic HCV infection have yet to be diagnosed but are likely to come to medical attention in the next decade.

The number of new infections per year, however, has declined from an average of 240,000 in the 1980s to about 25,000 in 2001. By 2020 almost all of the infected will have had the disease for more than 25 years. Between the years 2010 and 2020, most patients will then have reached an age of 55 to 75 years, many infected will die of other reasons before they will be diagnosed and started any anti-HCV therapy.

In this Highlight Report, BioSeeker has focused on three classes of therapeutic approaches as they represent different therapeutic strategies, but also as they target different time spans in the HCV market: immunomodulating substances, protease inhibitors, and vaccines. There is still a strong interest in developing new immunomodulating therapies for HCV despite the promise of the pegylated interferons. There is also increasing enthusiasm for targeting HCV molecular products such as protease inhibitors. The understanding of hepatitis C at a molecular level has also opened the door for more targeted development of a prophylactic or therapeutic HCV vaccine. The report analyzes the short, mid-range and long-term market development by studying three different therapeutic approaches in different developmental stages.

Several large pharmaceutical companies are conducting R&D related to HCV, but with different focus. BioSeeker Group tries to assess the competition between these therapeutic strategies and to correlate this with possible market development. Due to the high competition and a shrinking market some therapies will have difficulties to reach sufficient revenues within their lifecycle. Activities from a total of 50 companies are described.

Our Highlight Reports are produced to enable our customers to be updated on the progress within different sectors of the biotechnology industry, and will give you access to achievements and novel breakthroughs during the latest years of activities. Apart from the pharma industry itself, this report is of value to investors, science incubators, investigators, contract research organizations or any other types of organization that have an interest in new antifungal therapies.

Companies included in the report

Agouron, ALZA, Amarillo, Anadys, Axys, BioMedicines, Biopharm Group, BioVex, Boehringer Ingelheim, Bristol Myers Squibb, Chiron, Corvas, Dimethaid, Dynavax Technologies, Eli Lilly, Enzo, Epimmune, Eurodiagnostica, Fumapharm, Genencor, GeneTrol, GenPhar, GlaxoSmithKline, Hawaii Biotech Group, Human Genome Sciences, ICN Pharm., Immusystems, Inhale Thera., Innogenetics, InterCell, InterMune, Lexicon Genetics, Maxim Pharmaceuticals, Medivir, Merck, Metaphore Pharmaceuticals, Oxo Chemie, Pepgen Corp., Pharming, Phogen, Roche, Schering-Plough, SciClone, Toray Industries, Triangle Pharmaceuticals, Tripep, Vernalis, Vertex, Viragen, XTL Biopharmaceuticals



Get Full Details About This Report >>

US: 800.298.5699
Int'l: +1.240.747.3093
Buy this Report
Price and Delivery Options
Available by the section

Search Inside Report


 

About MarketResearch.com
MarketResearch.com is an online aggregator selling over 250,000 market research reports, company profiles and country profiles from over 650 research firms. Our reports will provide you with the critical business and competitive intelligence you need for strategic planning and marketing research. Coverage includes the US, UK, Europe, Asia and global markets.

 

© MarketResearch.com 2009