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HIV Update 2002 (7): July

Published by: Datamonitor

Published: Oct. 3, 2002 - 21 Pages


Table of Contents


Overview

Introduction

The monthly HIV update provides Datamonitor's assessment of the key market

events that took place during July 2002. Key events include new product

launches, clinical trial data and conference findings.

Scope

Key events are analyzed in the HIV market during July

Coverage includes emerging market headlines, R&D pipeline data, epidemiology

and disease specific factors.

Report Highlights

Biotech company pledges AIDS vaccine in three years.

Reasons to Purchase

Stay informed of all of the important market led events taking place in the

HIV market

Gain insight into the likely market impact of the events that took place in

July 2002 in the HIV market.

Report Highlights

Second generation fusion inhibitor holds promise.

PI boosting taken to the next level.

DRIVERS AND TRENDS

Latest data shows that an AIDS vaccine could be available as early as 2005.

Approval of such a vaccine could conceivably alter the balance of the epidemic.

However this may still be premature if the vaccine is not safe or globally

applicable.

Additional data from Roche shows that its second-generation fusion inhibitor

could be potent and safe in HIV-infected individuals. Although this fusion

inhibitor will not market till at least 2006, both physicians and patients are

placing their hopes on this new class of HIV drugs.

PI boosting strategies have provided physicians with an alternative means of

treating patients. Conventional PI therapy, although effective has proven

toxic to patients. Consequently PI boosting and double PI boosting have been

investigated in various contexts in order to maximize efficacy, whilst

minimizing toxicity.

COMPANY HEADLINES

A summary of the latest events from a company perspective

Vaxgen Claims that HIV Vaccine Could be Available in 3 Years

RESEARCH AND DEVELOPMENT HEADLINES

A summary of the key events from a pipeline drug perspective

Nonoxynol-9 Ineffective at Preventing HIV and Pregnancy

Promising Phase I/II Trial Data for T-1249

Double Boost May Give Kaletra the Edge

Early Trials Suggest Use for Growth Hormone in Combating HIV

DISEASE SPECIFIC HEADLINES

An overview of the epidemiological, research and clinical perspective

HAART Benefits Manifest in Reduced HIV Hospitalisations

Progression to AIDS not Influenced by Hepatitis C Infection

Cost Of AIDS Care Highlighted

Occupational HIV Prophylaxis Guidelines Proposed for EU

Severe HAART Related Hepatotoxicity Predictable by Sex

Skin Reactions Associated with CD8 Counts and Age

HIV Bone Pain May be on the Increase

HIV Matrix Protein Not Required for Nef-Boosted Infectivity

HIV Protection May Increase HCV Infection Risk

Short Term Success for Viral Suppression in Infants on HAART

Early Initiation of HAART May Benefit Asymptomatic Patients with High CD4 Cell

Counts

Salvage Patients May Benefit from Early Viramune to Sustiva Switch

Antibodies Active Against HIV Fusion Process

Repeated Murabutide Injections May Be Beneficial for HIV Patients

T-20 Administration Not A Cause For Compliance Concern?

EMERGING MARKETS HEADLINES

A summary of the key events from the emerging markets

HIV Manufacturers Agree to Supply Discounted Drugs to Caribbean

Simpler Treatment May Improve Proportions of Developing World HIV patients

Receiving Care





Abstract

Introduction: The monthly HIV update provides Datamonitor's assessment of the key market events that took place during July 2002. Key events include new product launches, clinical trial data and conference findings. Scope of the Report: * Key events are analyzed in the HIV market during July * Coverage includes emerging market headlines, R&D pipeline data, epidemiology and disease specific factors. Report Highlights: Biotech company pledges AIDS vaccine in three years. Second generation fusion inhibitor holds promise. PI boosting taken to the next level. Key Reasons to Buy this Report: * Stay informed of all of the important market led events taking place in the HIV market * Gain insight into the likely market impact of the events that took place in July 2002 in the HIV market.

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