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HIV Update 2002 (6): June

Published by: Datamonitor

Published: Oct. 3, 2002 - 25 Pages


Table of Contents


Overview

Introduction

June 2002 was an important month in the HIV market. Pricing pressure for HIV

therapies continued to intensify in the US market, with a major competitor

reprimanded for its pricing policy. The shift towards more fully recognising

side-effect profiles within treatment decisions continues, with clinical trial

data being published highlighting the importance of toxicity in maximising HIV

patients' QOL.

Scope

Datamonitor has provided a descriptive analysis of each of the key events,

commenting as to their likely market impact.

This Brief summarises the key events and developments that have taken place in

the HIV market during June 2002.

Report Highlights

Historically, the level of unmet need in the HIV market has meant that premuim

pricing strategies for new HIV products have been undertaken. However, the

increasing predominance of patient advocacy groups and awareness of healthcare

payors over the cost of HIV therapy is placing pressure on such pricing

strategies. Organisations such as Aids Healthcare Foundation in the US are now

seeking to restrict HIV sales force promotion activities on the basis of price.

Reasons to Purchase

Keep track of all of the important events taking place in the HIV market, with

comprehensive coverage of key clinical trial data and product news.

Gain insight into the likey market impact of the events that took place in

June in the HIV market.

DRIVERS AND TRENDS

The HIV pharmaceutical industry may start to face a changing trend with

increasing pressure from the developed world to cut prices of anti-retroviral

drugs. This is partly in response to overpricing of current drug, but also an

attempt to match price cuts in the developing world.

Not only is price an issue, but also side effects associated with currently

marketed drugs. Much more emphasis is being placed on quality of life issues,

with patients skipping doses if therapy becomes too hard to endure.

Consequently, much clinical research is being concentrated on attempting to

reduce drug-associated co-morbidities.

Current treatment strategies revolve around drugs that combat the virus after

it has infected an individual. Less emphasis is being placed on preventing

infection. Determining alternative avenues of combating HIV is at the

forefront of both patients and physicians minds.

COMPANY HEADLINES

A summary of the latest events from a company perspective

Anadys and Gilead Form Collaboration to Discover New Antiviral Compounds

GlaxoSmithKline Taken to Court Over Drug Pricing

Co-Distribution of Rapid HIV Kit: Agreement Between OraSure and Abbott

RESEARCH AND DEVELOPMENT HEADLINES

A summary of the key events from a clinical and pipeline drug perspective

Lipodystrophy Uncommon in Children taking HAART

Poor response to HAART may Boost Antifungal Sales

Ritonavir Could Combat Kaposi’s

New York AIDS Patients Given Glimmer of Hope

Ethnicity May Affect Side Effect Risks from HAART

Trials show Viread Effective in Treatment Experienced Patients

Limited HAART Risk During Pregnancy

Mortality and Pain Linked in HAART Treated HIV Infected Children

Mortality and Pain Linked in HAART Treated HIV Infected Children

Lopinavir Ritonavir Combination Proves Potent

Late Stage Symptoms Can Appear in Recently Infected HIV Patients

DISEASE SPECIFIC HEADLINES

An overview of the epidemiological and research perspective

T-Cell Repopulation Following HAART Linked to Thymus

Catabolic Cytokines Blamed for Loss of Lean Body Mass in HIV

Stem Cell Potential for HIV patient Immune Reconstitution

Gene Variation Ruled Out in HAART Complications

Monocytes Contribute to CD4 T-cell Apoptosis

EMERGING MARKETS HEADLINES

A summary of the key events from the emerging markets

HIV Subtype Differences May Not Affect Response to HAART

Heroin Use Related to Rise in HIV Incidence





Abstract

Introduction: June 2002 was an important month in the HIV market. Pricing pressure for HIV therapies continued to intensify in the US market, with a major competitor reprimanded for its pricing policy. The shift towards more fully recognizing side-effect profiles within treatment decisions continues, with clinical trial data being published highlighting the importance of toxicity in maximizing HIV patients' QOL. Scope of the Report: * Datamonitor has provided a descriptive analysis of each of the key events, commenting as to their likely market impact. * This Brief summarizes the key events and developments that have taken place in the HIV market during June 2002. Report Highlights: Historically, the level of unmet need in the HIV market has meant that premium pricing strategies for new HIV products have been undertaken. However, the increasing predominance of patient advocacy groups and awareness of healthcare payers over the cost of HIV therapy is placing pressure on such pricing strategies. Organizations such as AIDS Healthcare Foundation in the US are now seeking to restrict HIV sales force promotion activities on the basis of price. Key Reasons to Buy this Report: * Keep track of all of the important events taking place in the HIV market, with comprehensive coverage of key clinical trial data and product news. * Gain insight into the likely market impact of the events that took place in June 2002 in the HIV market.

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