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Side Effects of Male Cancers - Better Survival and Growing Social Acceptance of Impotence and Urinary Incontinence Equates to New Opportunities for Drug Therapies

Published by: Datamonitor

Published: Sep. 2, 2002 - 75 Pages


Table of Contents




Overview

Introduction

Male Cancers

DRIVERS AND TRENDS

Key drivers of the market for new approaches to the treatment of the side

effects of male cancers include increasing prevalence, increased visibility and

acknowledgement for side effects such as impotence and incontinence, increased

long-term survival leading to higher unmet need, and the commercial success of

products now entering the niche.

There will be higher consumer and physician demand for effective

pharmaceuticals.

Successful pharmaceuticals are likely to achieve commercial success because of

significant patient populations and high unmet need.

ETIOLOGY AND PREVALENCE

Identifies the side effects of male cancers that are the greatest barriers to

compliance and post-therapy quality of life. Projects the number of men who are

candidates for pharmaceutical therapy for side effects. Explains the etiology

and male cancer-specific frequency of impotence, incontinence, bone pain and

emotional changes—the hallmarks of therapy for many male cancers, and severe

enough to prevent or delay therapy in a significant population of men.

PHARMACOLOGICAL APPROACHES

Updates R&D managers on the clinical and commercial status of current and

pipeline agents for male cancers side effects. Products profiled include PEG5

erectile function drugs, incontinence, agents to control bone pain and

antidepressants commonly used in cancer patients.

ACTION POINTS

Prostate cancer is associated with the greatest unmet needs in terms of side

effects for male cancers and their treatment.

Pharmacological approaches to erectile dysfunction after prostate cancer offer

the greatest commercial potential in addressing unmet needs associated with

male cancer side effects

There is a clinical and commercial gap between pharmaceutical approaches to

managing the side effects of female cancers compared to those used for male

cancers. Closing this gap would translate into considerable commercial gain.

COMPARISONS WITH APPROACHES FOR WOMEN’S CANCERS

Gives insight into the historical factors behind the unmet needs in male cancers

side effects by comparing this indication with that for the more-prevalent, more

visible women’s cancers.

The side effects of male cancers have received less pharmaceutical attention

than have those associated with female cancers; the imbalance may be

attributable to differences in disease prevalence, to cultural and

psychological differences between men and women’s approaches to disease or to

the history of greater commercial success associated with women’s cancer

therapies.

Male cancers education and R&D are associated with fewer political,

educational or philanthropic efforts. Pharmaceutical companies interested in

expanding the commercial potential of their male cancers drugs could most

likely achieve greater visibility, with relatively little financial

investment, by establishing or working with a male cancer foundation on behalf

of patient and physician education and private research funding.

Abstract

Introduction: This Brief provides a survey and summary analysis of the commercially significant side effects of male cancers and their treatment. The Brief will prove most useful to pharmaceutical companies interested in opportunities for increased commercialization of drug therapy for managing male cancer side effects, and for closing the considerable gap in support for the side effects of male cancers (overall) versus female cancers such as breast and ovarian malignancies. Scope of this Report: * Estimates of the prevalence of male cancers across the major markets, 2001-2010 * Review and clinical analysis of the medical literature addressing male cancers side effects including impotence and incontinence * Analysis of the commercialization potential present in the context of these side effects within the male cancers population. Report Highlights: Prostate cancer is associated with the greatest unmet needs in terms of side effects for male cancers and their treatment. Pharmacological approaches to erectile dysfunction offer the greatest commercial potential in addressing unmet needs associated with male cancer side effects. There is a clinical and commercial gap between pharmaceutical approaches to managing the side effects of female cancers and those used for male cancers. Closing this gap would translate into considerable commercial gain. Key Reasons to Buy this Report: * Understand the prevalence of cancer-associated impotence and other side effects, and assess the level of opportunity for pharmaceutical responses * Grasp the present and emerging commercial dynamic among current and pipeline products for male cancers side effects. * Identify the potential for therapeutic control of side effects, and formulate strategies for using oncology as a platform for broader launch.

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